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X4 Pharmaceuticals, Inc

XFOR
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001501697

In the last 90 days, X4 Pharmaceuticals, Inc insiders filed 0 open-market purchases and 3 sales; 89 institutions reported holding it in 13F filings for Q2 2026, worth $491.9M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in X4 Pharmaceuticals, Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
52
+2 vs. Q3 2021
Shares held
17.6M
+1.70M (+10.7%) vs. Q3 2021
Total value
$40.2M
−$43.7M (−52.1%) vs. Q3 2021
New holders
13
12 more added
Sold out
11
14 more reduced

2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XFOR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 52 institutions
Q1 2021: 61 institutionsQ2 2021: 63 institutionsQ3 2021: 52 institutionsQ4 2021: 52 institutionsQ1 2022: 56 institutionsQ2 2022: 51 institutionsQ3 2022: 59 institutionsQ4 2022: 54 institutionsQ1 2023: 59 institutionsQ2 2023: 96 institutionsQ3 2023: 91 institutionsQ4 2023: 93 institutionsQ1 2024: 98 institutionsQ2 2024: 99 institutionsQ3 2024: 98 institutionsQ4 2024: 90 institutionsQ1 2025: 94 institutionsQ2 2025: 52 institutionsQ3 2025: 42 institutionsQ4 2025: 79 institutionsQ1 2026: 84 institutionsQ2 2026: 89 institutions
Value heldQ4 2021: $40.4M
Q1 2021: $139.0MQ2 2021: $111.5MQ3 2021: $85.7MQ4 2021: $40.4MQ1 2022: $30.7MQ2 2022: $16.6MQ3 2022: $74.0MQ4 2022: $60.2MQ1 2023: $53.7MQ2 2023: $219.2MQ3 2023: $122.6MQ4 2023: $87.1MQ1 2024: $147.1MQ2 2024: $60.7MQ3 2024: $67.4MQ4 2024: $73.3MQ1 2025: $23.6MQ2 2025: $5.33MQ3 2025: $55.3MQ4 2025: $357.7MQ1 2026: $407.0MQ2 2026: $491.9M
Institutions holding XFOR and their total value by quarter
QuarterHoldersValue
Q2 202689$491.9M
Q1 202684$407.0M
Q4 202579$357.7M
Q3 202542$55.3M
Q2 202552$5.33M
Q1 202594$23.6M
Q4 202490$73.3M
Q3 202498$67.4M
Q2 202499$60.7M
Q1 202498$147.1M
Q4 202393$87.1M
Q3 202391$122.6M
Q2 202396$219.2M
Q1 202359$53.7M
Q4 202254$60.2M
Q3 202259$74.0M
Q2 202251$16.6M
Q1 202256$30.7M
Q4 202152$40.4M
Q3 202152$85.7M
Q2 202163$111.5M
Q1 202161$139.0M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding X4 Pharmaceuticals, Inc; share changes are against Q3 2021.

Institutions holding XFOR in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Bain Capital Life Sciences Investors, LLC2,886,542$6.61M0.52%+767,002+36.2%Added
Ikarian Capital, LLC2,264,491$5.19M1.48%−275,426−10.8%Reduced
Point72 Asset Management, L.P.1,633,204$3.74M0.02%+1,633,204New
Tri Locum Partners LP1,578,947$3.62M1.45%+1,578,947New
AIGH Capital Management LLC1,464,099$3.35M1.05%−200,441−12.0%Reduced
OrbiMed Advisors LLC1,373,849$3.15M0.04%00.0%Unchanged
AXA S.A.1,151,819$2.64M0.01%+561,550+95.1%Added
Vanguard Group Inc933,240$2.14M0.00%−1,112−0.1%Reduced
BVF Inc847,879$1.94M0.07%00.0%Unchanged
Worth Venture Partners, LLC340,495$780.0K0.39%−45,980−11.9%Reduced
New Leaf Venture Partners, L.L.C.335,000$767.0K0.28%00.0%Unchanged
SV Health Investors, LLC311,490$713.0K0.46%00.0%Unchanged
Sio Capital Management, LLC276,909$634.0K0.19%−527,688−65.6%Reduced
BlackRock Inc.274,548$628.0K0.00%+6,098+2.3%Added
Boothbay Fund Management, LLC238,566$546.0K0.02%−29,016−10.8%Reduced
Millennium Management LLC202,483$464.0K0.00%−64,885−24.3%Reduced
Geode Capital Management, LLC178,060$407.0K0.00%00.0%Unchanged
Ensign Peak Advisors, Inc176,530$404.0K0.00%+147,937+517.4%Added
Renaissance Technologies LLC137,294$314.0K0.00%+16,900+14.0%Added
Kennedy Capital Management, Inc.131,501$301.0K0.01%+131,501New
Cormorant Asset Management, LP103,980$238.0K0.01%00.0%Unchanged
Susquehanna International Group, LLP78,271$179.0K0.00%−59,760−43.3%Reduced
Citadel Advisors LLC77,700$178.0K0.00%+43,768+129.0%Added
Northern Trust Corp67,504$155.0K0.00%−355−0.5%Reduced
Dimensional Fund Advisors LP66,170$152.0K0.00%−7,325−10.0%Reduced
Marshall Wace, LLP60,479$139.0K0.00%+35,256+139.8%Added
Acadian Asset Management LLC57,270$130.0K0.00%+57,270New
FMR LLC53,031$121.0K0.00%−99,800−65.3%Reduced
State Street Corp48,480$111.0K0.00%00.0%Unchanged
Bleichroeder LP35,730$82.0K0.01%00.0%Unchanged
Norges Bank27,700$63.0K0.00%00.0%Unchanged
Goldman Sachs Group Inc20,949$48.0K0.00%+10,474+100.0%Added
XTX Topco Ltd19,938$46.0K0.03%+19,938New
Group One Trading, L.P.13,750$31.0K0.00%+11,667+560.1%Added
Connor, Clark & Lunn Investment Management Ltd.12,786$29.0K0.00%+12,786New
Morgan Stanley12,058$27.0K0.00%+3,258+37.0%Added
Engineers Gate Manager LP11,874$27.0K0.00%+11,874New
The PNC Financial Services Group, Inc.10,350$24.0K0.00%00.0%Unchanged
Moody Lynn & Lieberson, LLC10,000$23.0K0.00%+10,000New
Mayflower Financial Advisors, LLC10,000$23.0K0.00%+10,000New
Bank of America Corp9,406$22.0K0.00%−7,776−45.3%Reduced
Barclays PLC7,804$18.0K0.00%−2,095−21.2%Reduced
American Portfolios Advisors6,250$14.3K0.00%00.0%Unchanged
Simplex Trading, LLC5,309$12.0K0.00%+5,256+9,917.0%Added
Clearstead Advisors, LLC2,100$5.00K0.00%+2,000+2,000.0%Added
High Net Worth Advisory Group LLC1,100$3.00K0.00%+1,100New
UBS Group AG668$2.00K0.00%+668New
Rockefeller Capital Management L.P.1,000$2.00K0.00%+1,000New
Advisor Group Holdings, Inc.400$1.00K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA278$6370.00%−17−5.8%Reduced
Wells Fargo & Company125$00.00%00.0%Unchanged
JPMorgan Chase & Co203$00.00%+203New
Altium Capital Management LP0$00.00%−804,598−100.0%Sold out
Monashee Investment Management LLC0$00.00%−561,421−100.0%Sold out
Driehaus Capital Management LLC0$00.00%−505,752−100.0%Sold out
Ergoteles LLC0$00.00%−68,938−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−45,893−100.0%Sold out
HRT Financial LP0$00.00%−34,719−100.0%Sold out
Minot Wealth Management LLC0$00.00%−17,000−100.0%Sold out
Trexquant Investment LP0$00.00%−16,625−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−1,250−100.0%Sold out
IFP Advisors, Inc0$00.00%−1,000−100.0%Sold out
Harbour Investments, Inc.0$00.00%−10−100.0%Sold out
Polaris Venture Management Co. V, L.L.C.––––Not filed
Marshall Wace North America L.P.––––Not filed