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X4 Pharmaceuticals, Inc

XFOR
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001501697

In the last 90 days, X4 Pharmaceuticals, Inc insiders filed 0 open-market purchases and 3 sales; 89 institutions reported holding it in 13F filings for Q2 2026, worth $463.0M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in X4 Pharmaceuticals, Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
84
+7 vs. Q4 2025
Shares held
93.9M
+7.90M (+9.2%) vs. Q4 2025
Total value
$388.1M
+$44.1M (+12.8%) vs. Q4 2025
New holders
18
22 more added
Sold out
11
23 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XFOR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 84 institutions
Q1 2021: 61 institutionsQ2 2021: 63 institutionsQ3 2021: 52 institutionsQ4 2021: 52 institutionsQ1 2022: 56 institutionsQ2 2022: 51 institutionsQ3 2022: 59 institutionsQ4 2022: 54 institutionsQ1 2023: 59 institutionsQ2 2023: 96 institutionsQ3 2023: 91 institutionsQ4 2023: 93 institutionsQ1 2024: 98 institutionsQ2 2024: 99 institutionsQ3 2024: 98 institutionsQ4 2024: 90 institutionsQ1 2025: 94 institutionsQ2 2025: 52 institutionsQ3 2025: 42 institutionsQ4 2025: 79 institutionsQ1 2026: 84 institutionsQ2 2026: 89 institutions
Value heldQ1 2026: $388.1M
Q1 2021: $138.7MQ2 2021: $107.8MQ3 2021: $85.7MQ4 2021: $40.2MQ1 2022: $28.6MQ2 2022: $15.5MQ3 2022: $66.9MQ4 2022: $60.2MQ1 2023: $53.6MQ2 2023: $219.1MQ3 2023: $122.6MQ4 2023: $81.2MQ1 2024: $143.2MQ2 2024: $58.9MQ3 2024: $67.3MQ4 2024: $73.2MQ1 2025: $23.3MQ2 2025: $5.33MQ3 2025: $55.3MQ4 2025: $357.7MQ1 2026: $388.1MQ2 2026: $463.0M
Institutions holding XFOR and their total value by quarter
QuarterHoldersValue
Q2 202689$463.0M
Q1 202684$388.1M
Q4 202579$357.7M
Q3 202542$55.3M
Q2 202552$5.33M
Q1 202594$23.3M
Q4 202490$73.2M
Q3 202498$67.3M
Q2 202499$58.9M
Q1 202498$143.2M
Q4 202393$81.2M
Q3 202391$122.6M
Q2 202396$219.1M
Q1 202359$53.6M
Q4 202254$60.2M
Q3 202259$66.9M
Q2 202251$15.5M
Q1 202256$28.6M
Q4 202152$40.2M
Q3 202152$85.7M
Q2 202163$107.8M
Q1 202161$138.7M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding X4 Pharmaceuticals, Inc; share changes are against Q4 2025.

Institutions holding XFOR in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Morgan Stanley9,466,992$39.1M0.00%+1,258,977+15.3%Added
Empery Asset Management, LP8,944,118$36.9M44.50%−6,987−0.1%Reduced
FMR LLC8,103,400$33.5M0.00%−395,700−4.7%Reduced
Bain Capital Life Sciences Investors, LLC7,967,454$32.9M2.97%00.0%Unchanged
Perceptive Advisors LLC6,737,648$27.8M0.55%+423,196+6.7%Added
Saturn V Capital Management LLC6,456,646$26.7M4.83%+656,116+11.3%Added
Deep Track Capital, LP6,339,535$26.2M0.54%+1,325,874+26.4%Added
Kalehua Capital Management LLC3,722,840$15.4M10.88%00.0%Unchanged
Vanguard Capital Management LLC3,497,612$14.4M0.00%+3,497,612New
Braidwell LP3,272,954$13.5M0.45%−95,950−2.8%Reduced
NEA Management Company, LLC3,233,743$13.4M0.76%00.0%Unchanged
Rosalind Advisors, Inc.3,214,766$13.3M5.44%+608,846+23.4%Added
Blackstone Group Inc.2,681,922$11.1M0.05%00.0%Unchanged
Trails Edge Capital Partners, LP2,571,478$10.6M2.50%00.0%Unchanged
Nantahala Capital Management, LLC2,449,468$10.1M0.63%00.0%Unchanged
BVF Inc2,233,742$9.23M0.29%00.0%Unchanged
Samsara BioCapital, LLC1,832,566$7.57M0.74%−127,434−6.5%Reduced
BlackRock, Inc.1,211,794$5.00M0.00%−15,014−1.2%Reduced
Millennium Management LLC1,210,514$5.00M0.00%+1,154,536+2,062.5%Added
Woodline Partners LP1,001,095$4.13M0.02%+2400.0%Added
Geode Capital Management, LLC939,726$3.88M0.00%−721−0.1%Reduced
Goldman Sachs Group Inc882,134$3.64M0.00%+50,244+6.0%Added
Susquehanna International Group, LLP856,222$3.54M0.00%+834,087+3,768.2%Added
StemPoint Capital LP850,742$3.51M0.68%−47,723−5.3%Reduced
Vanguard Fiduciary Trust Co480,733$1.99M0.00%+480,733New
State Street Corp403,534$1.67M0.00%+205,300+103.6%Added
Marshall Wace, LLP336,834$1.39M0.00%+256,378+318.7%Added
Stonepine Capital Management, LLC335,309$1.38M1.22%−258,264−43.5%Reduced
VR Adviser, LLC330,525$1.37M0.05%+330,525New
UBS Group AG267,340$1.10M0.00%+263,211+6,374.7%Added
Acorn Capital Advisors, LLC234,039$966.6K0.27%−39,310−14.4%Reduced
Qube Research & Technologies Ltd218,954$904.3K0.00%+151,207+223.2%Added
Northern Trust Corp178,235$736.1K0.00%00.0%Unchanged
Pale Fire Capital SE167,590$692.1K0.06%00.0%Unchanged
Bank of America Corp150,676$622.3K0.00%+114,915+321.3%Added
Affinity Asset Advisors, LLC145,000$598.9K0.04%00.0%Unchanged
Palumbo Wealth Management LLC131,014$541.1K0.13%+17,657+15.6%Added
Brevan Howard Capital Management LP127,321$525.8K0.01%+127,321New
Susquehanna Portfolio Strategies, LLC102,599$423.7K0.01%+59,340+137.2%Added
Dynamic Technology Lab Private Ltd36,221$384.7K0.06%+36,221New
Charles Schwab Investment Management Inc66,749$275.7K0.00%−39−0.1%Reduced
Omers Administration Corp57,300$236.6K0.00%−51,900−47.5%Reduced
Hudson Bay Capital Management LP50,287$207.7K0.00%+18,048+56.0%Added
Catalyst Funds Management Pty Ltd47,383$195.7K0.03%+47,383New
Jane Street Group, LLC37,143$153.4K0.00%−54,270−59.4%Reduced
Citigroup Inc35,765$147.7K0.00%+3,433+10.6%Added
Vanguard Global Advisers, LLC32,977$136.2K0.00%+32,977New
Diametric Capital, LP28,973$119.7K0.03%+28,973New
Stifel Financial Corp21,789$90.0K0.00%+1,293+6.3%Added
Invesco Ltd.19,968$82.5K0.00%+19,968New
Schonfeld Strategic Advisors LLC19,514$80.6K0.00%+19,514New
Jefferies Financial Group Inc.19,474$80.4K0.00%−6,644−25.4%Reduced
Caxton Corp15,557$64.2K1.60%00.0%Unchanged
ExodusPoint Capital Management, LP14,703$60.7K0.00%−64,369−81.4%Reduced
Two Sigma Investments, LP13,868$57.3K0.00%−3,378−19.6%Reduced
Creative Planning13,819$57.1K0.00%−2,608−15.9%Reduced
Virtu Financial LLC12,730$53.0K0.00%−9,759−43.4%Reduced
Jump Financial, LLC12,317$50.9K0.00%+12,317New
JustInvest LLC11,525$47.6K0.00%+11,525New
SummitTX Capital, L.P.11,200$46.3K0.00%+11,200New
Winton Group Ltd10,600$43.8K0.00%+10,600New
Indivisible Partners10,000$37.0K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA4,756$19.6K0.00%+4,245+830.7%Added
Barclays PLC2,814$11.6K0.00%−54,686−95.1%Reduced
Signaturefd, LLC1,996$8.24K0.00%−758−27.5%Reduced
The PNC Financial Services Group, Inc.1,759$7.26K0.00%00.0%Unchanged
State of Wyoming1,065$4.40K0.00%+1,065New
Russell Investments Group, Ltd.729$3.01K0.00%00.0%Unchanged
Acadian Asset Management LLC802$3.00K0.00%+802New
Group One Trading, L.P.712$2.94K0.00%−3,286−82.2%Reduced
Bleichroeder LP595$2.46K0.00%00.0%Unchanged
Farther Finance Advisors, LLC331$1.44K0.00%00.0%Unchanged
Allworth Financial LP310$1.28K0.00%−405−56.6%Reduced
Ronald Blue Trust, Inc.284$1.17K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)180$7430.00%−10,266−98.3%Reduced
Quadrant Capital Group LLC128$5290.00%+128New
Parallel Advisors, LLC116$4790.00%+116New
SBI Securities Co., Ltd.54$2230.00%+4+8.0%Added
Jones Financial Companies LLLP38$1540.00%00.0%Unchanged
Rockefeller Capital Management L.P.33$1360.00%00.0%Unchanged
JPMorgan Chase & Co33$1320.00%−4,548−99.3%Reduced
HighMark Wealth Management LLC6$240.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co5$210.00%00.0%Unchanged
Royal Bank of Canada115$00.00%+11+10.6%Added
Siren, L.L.C.0$00.00%−1,500,000−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−808,154−100.0%Sold out
Silverarc Capital Management, LLC0$00.00%−357,387−100.0%Sold out
Citadel Advisors LLC0$00.00%−128,675−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−64,505−100.0%Sold out
Man Group plc0$00.00%−24,187−100.0%Sold out
Lighthouse Investment Partners, LLC0$00.00%−22,200−100.0%Sold out
Squarepoint Ops LLC0$00.00%−12,518−100.0%Sold out
Fortitude Family Office, LLC0$00.00%−137−100.0%Sold out
GWM Advisors LLC0$00.00%−33−100.0%Sold out
RMG Wealth Management LLC0$00.00%−28−100.0%Sold out
Vanguard Group Inc––––Not filed
CIBC Private Wealth Group, LLC––––Not filed