Twist Bioscience Corp
TWST- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001581280
In the last 90 days, Twist Bioscience Corp insiders filed 0 open-market purchases and 30 sales; 337 institutions reported holding it in 13F filings for Q2 2026, worth $7.85B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Twist Bioscience Corp as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 244
- +10 vs. Q3 2025
- Shares held
- 75.0M
- +1.35M (+1.8%) vs. Q3 2025
- Total value
- $2.38B
- +$306.8M (+14.8%) vs. Q3 2025
- New holders
- 48
- 75 more added
- Sold out
- 38
- 77 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TWST on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 337 | $7.85B |
| Q1 2026 | 281 | $3.66B |
| Q4 2025 | 244 | $2.38B |
| Q3 2025 | 239 | $2.08B |
| Q2 2025 | 244 | $2.62B |
| Q1 2025 | 263 | $2.73B |
| Q4 2024 | 247 | $3.08B |
| Q3 2024 | 246 | $2.99B |
| Q2 2024 | 263 | $3.25B |
| Q1 2024 | 238 | $2.30B |
| Q4 2023 | 219 | $2.46B |
| Q3 2023 | 196 | $1.34B |
| Q2 2023 | 194 | $1.39B |
| Q1 2023 | 203 | $956.8M |
| Q4 2022 | 199 | $1.45B |
| Q3 2022 | 221 | $2.04B |
| Q2 2022 | 205 | $2.01B |
| Q1 2022 | 213 | $2.92B |
| Q4 2021 | 237 | $3.96B |
| Q3 2021 | 238 | $5.20B |
| Q2 2021 | 245 | $6.40B |
| Q1 2021 | 240 | $5.82B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Twist Bioscience Corp; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| ARK Investment Management LLCSuperinvestorARK Invest | 7,559,495 | $239.8M | 1.59% | +832,687+12.4% | Added |
| William Blair Investment Management, LLC | 5,954,429 | $188.9M | 0.53% | +1,812,146+43.7% | Added |
| BlackRock, Inc. | 5,894,972 | $187.0M | 0.00% | −283,404−4.6% | Reduced |
| Artisan Partners Limited Partnership | 5,830,205 | $184.9M | 0.28% | −580,695−9.1% | Reduced |
| Vanguard Group Inc | 5,776,198 | $183.2M | 0.00% | +8,049+0.1% | Added |
| EdgePoint Investment Group Inc. | 5,377,991 | $170.6M | 1.40% | +1,295,672+31.7% | Added |
| State Street Corp | 3,627,818 | $115.1M | 0.00% | +538,755+17.4% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 1,902,829 | $60.4M | 0.04% | −217,377−10.3% | Reduced |
| Nikko Asset Management Americas, Inc. | 1,902,829 | $60.3M | 0.70% | −217,377−10.3% | Reduced |
| Soleus Capital Management, L.P. | 1,861,802 | $59.1M | 2.51% | −4,432−0.2% | Reduced |
| Goldman Sachs Group Inc | 1,696,594 | $53.8M | 0.01% | +69,574+4.3% | Added |
| Millennium Management LLC | 1,497,746 | $47.5M | 0.03% | −296,104−16.5% | Reduced |
| Geode Capital Management, LLC | 1,459,274 | $46.3M | 0.00% | +10,861+0.7% | Added |
| Thrivent Financial for Lutherans | 1,361,355 | $43.2M | 0.08% | −101,730−7.0% | Reduced |
| Invesco Ltd. | 1,290,271 | $40.9M | 0.00% | −504,872−28.1% | Reduced |
| Baillie Gifford & Co | 1,276,195 | $40.5M | 0.03% | +13,456+1.1% | Added |
| UBS Asset Management Americas Inc | 1,173,100 | $37.2M | 0.01% | +49,403+4.4% | Added |
| First Light Asset Management, LLC | 1,140,771 | $36.2M | 2.77% | −54,112−4.5% | Reduced |
| Morgan Stanley | 866,356 | $27.5M | 0.00% | −625,750−41.9% | Reduced |
| American Century Companies Inc | 865,634 | $27.5M | 0.01% | +27,570+3.3% | Added |
| Tao Capital Management LP | 828,815 | $26.3M | 22.63% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 815,369 | $25.9M | 0.01% | +24,476+3.1% | Added |
| Wellington Management Group LLP | 813,122 | $25.8M | 0.00% | +513,309+171.2% | Added |
| UBS Group AG | 662,317 | $21.0M | 0.00% | +147,389+28.6% | Added |
| Jennison Associates LLC | 618,933 | $19.6M | 0.01% | −15,667−2.5% | Reduced |
| New York State Common Retirement Fund | 591,180 | $18.8M | 0.03% | +6,486+1.1% | Added |
| Balyasny Asset Management LLC | 579,370 | $18.4M | 0.03% | +333,134+135.3% | Added |
| Charles Schwab Investment Management Inc | 548,392 | $17.4M | 0.00% | −25,240−4.4% | Reduced |
| StemPoint Capital LP | 518,355 | $16.4M | 2.82% | +518,355 | New |
| Northern Trust Corp | 504,838 | $16.0M | 0.00% | −20,204−3.8% | Reduced |
| Freshford Capital Management, LLC | 420,171 | $13.3M | 5.35% | +420,171 | New |
| BNP Paribas Arbitrage, SA | 415,609 | $13.2M | 0.01% | +294,144+242.2% | Added |
| Citigroup Inc | 401,282 | $12.7M | 0.01% | +307,824+329.4% | Added |
| Bank of America Corp | 399,354 | $12.7M | 0.00% | −51,020−11.3% | Reduced |
| Blue Water Life Science Advisors, LLC | 383,000 | $12.1M | 7.63% | +383,000 | New |
| Davy Global Fund Management Ltd | 371,552 | $11.8M | 0.81% | +105,701+39.8% | Added |
| Standard Life Aberdeen plc | 308,116 | $9.77M | 0.02% | −12,167−3.8% | Reduced |
| Nuveen, LLC | 290,556 | $9.22M | 0.00% | −261,585−47.4% | Reduced |
| Peregrine Capital Management LLC | 288,283 | $9.14M | 0.28% | −3,870−1.3% | Reduced |
| SEI Investments Co | 270,099 | $8.57M | 0.01% | −26,819−9.0% | Reduced |
| Silvercrest Asset Management Group LLC | 269,093 | $8.54M | 0.06% | +767+0.3% | Added |
| Osterweis Capital Management Inc | 256,878 | $8.15M | 0.34% | +256,878 | New |
| Jupiter Asset Management Ltd | 243,669 | $7.73M | 0.06% | −1,429−0.6% | Reduced |
| Pictet Asset Management Holding SA | 222,647 | $7.30M | 0.01% | +115,880+108.5% | Added |
| JPMorgan Chase & Co | 215,147 | $6.82M | 0.00% | −803,087−78.9% | Reduced |
| Ensign Peak Advisors, Inc | 212,593 | $6.74M | 0.01% | −13,679−6.0% | Reduced |
| Trexquant Investment LP | 198,473 | $6.30M | 0.06% | −134,225−40.3% | Reduced |
| Barclays PLC | 194,071 | $6.16M | 0.00% | −32,597−14.4% | Reduced |
| Bank of New York Mellon Corp | 182,941 | $5.80M | 0.00% | −315,320−63.3% | Reduced |
| Qube Research & Technologies Ltd | 171,972 | $5.45M | 0.01% | −400,463−70.0% | Reduced |
| Legal & General Group Plc | 171,206 | $5.43M | 0.00% | +45,920+36.7% | Added |
| State of Michigan Retirement System | 153,172 | $4.86M | 0.02% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 139,893 | $4.44M | 0.02% | +74,444+113.7% | Added |
| Oddo BHF Asset Management SAS | 135,650 | $4.30M | 0.16% | −36,137−21.0% | Reduced |
| Neuberger Berman Group LLC | 135,622 | $4.30M | 0.00% | −25,552−15.9% | Reduced |
| Vestmark Advisory Solutions, Inc. | 129,990 | $4.12M | 0.06% | +12,741+10.9% | Added |
| AQR Capital Management LLC | 129,552 | $4.11M | 0.00% | −78,356−37.7% | Reduced |
| Swiss National Bank | 119,000 | $3.77M | 0.00% | +2,900+2.5% | Added |
| Rafferty Asset Management, LLC | 114,258 | $3.62M | 0.01% | −100.0% | Reduced |
| Natixis | 103,688 | $3.29M | 0.01% | +103,688 | New |
| Jacobs Levy Equity Management, Inc | 103,117 | $3.27M | 0.01% | −394,021−79.3% | Reduced |
| Fred Alger Management, LLC | 94,111 | $2.99M | 0.01% | −2,950−3.0% | Reduced |
| Rhumbline Advisers | 91,122 | $2.89M | 0.00% | −4,085−4.3% | Reduced |
| Blair William & Co | 81,561 | $2.59M | 0.01% | +22,482+38.1% | Added |
| Nomura Asset Management International Inc. | 80,552 | $2.56M | 0.00% | +80,552 | New |
| Aquatic Capital Management LLC | 78,469 | $2.49M | 0.07% | +56,206+252.5% | Added |
| SG Americas Securities, LLC | 76,484 | $2.43M | 0.00% | +59,500+350.3% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 76,318 | $2.42M | 0.00% | +855+1.1% | Added |
| Wells Fargo & Company | 74,819 | $2.37M | 0.00% | +28,059+60.0% | Added |
| HRT Financial LP | 73,127 | $2.32M | 0.01% | +73,127 | New |
| Susquehanna International Group, LLP | 70,753 | $2.24M | 0.00% | +53,798+317.3% | Added |
| FMR LLC | 68,937 | $2.19M | 0.00% | −150,595−68.6% | Reduced |
| Alliancebernstein L.P. | 66,524 | $2.11M | 0.00% | −76−0.1% | Reduced |
| Lazard Asset Management LLC | 66,027 | $2.09M | 0.00% | −12,323−15.7% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 65,122 | $2.08M | 0.00% | −468−0.7% | Reduced |
| Canada Pension Plan Investment Board | 60,200 | $1.91M | 0.00% | +11,300+23.1% | Added |
| Price T Rowe Associates Inc | 58,985 | $1.87M | 0.00% | +5,135+9.5% | Added |
| California State Teachers Retirement System | 58,337 | $1.85M | 0.00% | −80.0% | Reduced |
| Conestoga Capital Advisors, LLC | 56,785 | $1.80M | 0.03% | +1,185+2.1% | Added |
| Deutsche Bank AG | 55,671 | $1.77M | 0.00% | −44,844−44.6% | Reduced |
| Franklin Resources Inc | 53,881 | $1.71M | 0.00% | −204,818−79.2% | Reduced |
| LPL Financial LLC | 53,043 | $1.68M | 0.00% | +17,644+49.8% | Added |
| Ieq Capital, LLC | 51,335 | $1.63M | 0.00% | +51+0.1% | Added |
| Clarius Group, LLC | 49,635 | $1.57M | 0.09% | 00.0% | Unchanged |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 44,668 | $1.45M | 0.00% | +4,704+11.8% | Added |
| Profund Advisors LLC | 42,355 | $1.34M | 0.04% | +17,701+71.8% | Added |
| Algert Global LLC | 40,601 | $1.29M | 0.02% | −19,700−32.7% | Reduced |
| HighMark Wealth Management LLC | 39,462 | $1.25M | 0.51% | 00.0% | Unchanged |
| Envestnet Asset Management Inc | 38,649 | $1.23M | 0.00% | −11,191−22.5% | Reduced |
| Victory Capital Management Inc | 37,555 | $1.19M | 0.00% | −9,690−20.5% | Reduced |
| Squarepoint Ops LLC | 35,717 | $1.13M | 0.00% | −40,080−52.9% | Reduced |
| Maxi Investments CY Ltd | 35,000 | $1.11M | 0.20% | +35,000 | New |
| State of Wisconsin Investment Board | 34,547 | $1.10M | 0.00% | −2,639−7.1% | Reduced |
| Ameriprise Financial Inc | 33,348 | $1.06M | 0.00% | −62,933−65.4% | Reduced |
| MetLife Investment Management | 33,236 | $1.05M | 0.01% | −1,491−4.3% | Reduced |
| Royal Bank of Canada | 33,234 | $1.05M | 0.00% | −95,256−74.1% | Reduced |
| Citadel Advisors LLC | 32,049 | $1.02M | 0.00% | −83,196−72.2% | Reduced |
| Two Sigma Advisers, LP | 31,400 | $996.0K | 0.00% | +5,400+20.8% | Added |
| Benjamin Edwards Inc | 29,632 | $939.8K | 0.01% | +1,309+4.6% | Added |
| D. E. Shaw & Co., Inc. | 27,581 | $874.9K | 0.00% | +27,581 | New |