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Twist Bioscience Corp

TWST
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001581280

In the last 90 days, Twist Bioscience Corp insiders filed 0 open-market purchases and 30 sales; 337 institutions reported holding it in 13F filings for Q2 2026, worth $7.85B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Twist Bioscience Corp as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
244
+10 vs. Q3 2025
Shares held
75.0M
+1.35M (+1.8%) vs. Q3 2025
Total value
$2.38B
+$306.8M (+14.8%) vs. Q3 2025
New holders
48
75 more added
Sold out
38
77 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TWST on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 244 institutions
Q1 2021: 240 institutionsQ2 2021: 245 institutionsQ3 2021: 238 institutionsQ4 2021: 237 institutionsQ1 2022: 213 institutionsQ2 2022: 205 institutionsQ3 2022: 221 institutionsQ4 2022: 199 institutionsQ1 2023: 203 institutionsQ2 2023: 194 institutionsQ3 2023: 196 institutionsQ4 2023: 219 institutionsQ1 2024: 238 institutionsQ2 2024: 263 institutionsQ3 2024: 246 institutionsQ4 2024: 247 institutionsQ1 2025: 263 institutionsQ2 2025: 244 institutionsQ3 2025: 239 institutionsQ4 2025: 244 institutionsQ1 2026: 281 institutionsQ2 2026: 337 institutions
Value heldQ4 2025: $2.38B
Q1 2021: $5.82BQ2 2021: $6.40BQ3 2021: $5.20BQ4 2021: $3.96BQ1 2022: $2.92BQ2 2022: $2.01BQ3 2022: $2.04BQ4 2022: $1.45BQ1 2023: $956.8MQ2 2023: $1.39BQ3 2023: $1.34BQ4 2023: $2.46BQ1 2024: $2.30BQ2 2024: $3.25BQ3 2024: $2.99BQ4 2024: $3.08BQ1 2025: $2.73BQ2 2025: $2.62BQ3 2025: $2.08BQ4 2025: $2.38BQ1 2026: $3.66BQ2 2026: $7.85B
Institutions holding TWST and their total value by quarter
QuarterHoldersValue
Q2 2026337$7.85B
Q1 2026281$3.66B
Q4 2025244$2.38B
Q3 2025239$2.08B
Q2 2025244$2.62B
Q1 2025263$2.73B
Q4 2024247$3.08B
Q3 2024246$2.99B
Q2 2024263$3.25B
Q1 2024238$2.30B
Q4 2023219$2.46B
Q3 2023196$1.34B
Q2 2023194$1.39B
Q1 2023203$956.8M
Q4 2022199$1.45B
Q3 2022221$2.04B
Q2 2022205$2.01B
Q1 2022213$2.92B
Q4 2021237$3.96B
Q3 2021238$5.20B
Q2 2021245$6.40B
Q1 2021240$5.82B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Twist Bioscience Corp; share changes are against Q3 2025.

Institutions holding TWST in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Exchange Traded Concepts, LLC26,323$835.0K0.01%−2,778−9.5%Reduced
Comprehensive Financial Management LLC26,273$833.4K0.03%00.0%Unchanged
Manufacturers Life Insurance Company, The25,865$820.4K0.00%−2,268−8.1%Reduced
Janus Henderson Group PLC25,580$810.6K0.00%00.0%Unchanged
Intech Investment Management LLC25,477$808.1K0.01%+643+2.6%Added
D.A. Davidson & Co.25,237$800.5K0.00%+305+1.2%Added
Knights of Columbus Asset Advisors LLC23,005$729.7K0.04%−117−0.5%Reduced
Raymond James Financial Inc22,959$728.3K0.00%−18,850−45.1%Reduced
Russell Investments Group, Ltd.22,444$711.9K0.00%−41,454−64.9%Reduced
Guggenheim Capital LLC22,428$711.4K0.01%−1,312−5.5%Reduced
Prelude Capital Management, LLC22,035$699.0K0.05%+22,035New
US Bancorp21,366$677.7K0.00%+20,594+2,667.6%Added
Meridiem Capital Partners LP21,205$672.6K0.04%+21,205New
Zurcher Kantonalbank (Zurich Cantonalbank)21,057$667.9K0.00%+2,893+15.9%Added
Brandywine Managers, LLC20,970$665.2K0.33%00.0%Unchanged
Steel Peak Wealth Management LLC20,868$661.9K0.02%+2,570+14.0%Added
Handelsbanken Fonder AB20,400$647.0K0.00%+2,500+14.0%Added
Odyssean, LLC18,935$600.6K0.43%+18,935New
State Board of Administration of Florida Retirement System18,539$588.1K0.00%00.0%Unchanged
CIBC Private Wealth Group, LLC18,028$571.8K0.00%+10.0%Added
Quantinno Capital Management LP17,675$560.7K0.00%+17,675New
Virginia Retirement Systems Et Al17,538$556.3K0.00%−2,150−10.9%Reduced
Arizona State Retirement System16,810$533.2K0.00%−874−4.9%Reduced
Jump Financial, LLC16,707$529.9K0.01%+16,707New
Police & Firemen's Retirement System of New Jersey15,308$485.6K0.00%−1,057−6.5%Reduced
Cambridge Investment Research Advisors, Inc.15,236$483.0K0.00%+15,236New
Quadrature Capital Ltd14,998$475.7K0.00%+14,998New
Rockefeller Capital Management L.P.14,970$474.8K0.00%+3,359+28.9%Added
CWM Advisors, LLC14,808$469.7K0.04%−1,595−9.7%Reduced
Pekin Hardy Strauss, Inc.14,450$458.4K0.04%+14,450New
ProShare Advisors LLC13,636$432.5K0.00%+1,375+11.2%Added
KLP Kapitalforvaltning AS12,900$409.2K0.00%+800+6.6%Added
Massar Capital Management, LP12,250$388.6K0.08%+12,250New
QRG Capital Management, Inc.12,049$382.2K0.00%+325+2.8%Added
Isthmus Partners, LLC11,145$353.5K0.04%00.0%Unchanged
Voya Investment Management LLC10,598$336.2K0.00%00.0%Unchanged
Quantbot Technologies LP10,252$325.2K0.01%+10,252New
Creative Planning10,211$323.9K0.00%+10,211New
Great West Life Assurance Co10,153$321.0K0.00%−10,332−50.4%Reduced
Arrowpoint Investment Partners (Singapore) Pte. Ltd.9,992$316.9K0.05%+9,992New
China Universal Asset Management Co., Ltd.9,964$316.1K0.02%−616−5.8%Reduced
Quest Partners LLC9,455$299.9K0.02%−13,100−58.1%Reduced
Entropy Technologies, LP9,132$289.7K0.02%+9,132New
Geneos Wealth Management Inc.8,950$283.9K0.01%+3,500+64.2%Added
Teacher Retirement System of Texas8,935$283.4K0.00%−5,732−39.1%Reduced
Cerity Partners LLC8,865$281.2K0.00%−204−2.2%Reduced
Keybank National Association8,747$277.5K0.00%+10.0%Added
HSBC Holdings PLC8,654$276.3K0.00%−17,384−66.8%Reduced
Cetera Investment Advisers8,424$267.2K0.00%+8,424New
VARCOV Co.8,278$262.6K0.10%+8,278New
Clearstead Advisors, LLC8,013$254.2K0.00%+7,986+29,577.8%Added
Stifel Financial Corp7,769$246.4K0.00%+271+3.6%Added
Los Angeles Capital Management LLC7,884$245.7K0.00%+7,884New
Farallon Capital Management, L.L.C.7,650$242.7K0.00%00.0%Unchanged
Mercer Global Advisors Inc7,619$241.7K0.00%+7,619New
Mariner, LLC6,926$219.9K0.00%−1,557−18.4%Reduced
Advisor Group Holdings, Inc.6,427$203.9K0.00%−1,176−15.5%Reduced
Axxcess Wealth Management, LLC6,323$200.6K0.00%+6,323New
Public Employees Retirement Association of Colorado5,056$160.0K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.4,940$156.7K0.00%00.0%Unchanged
CWM, LLC4,738$150.0K0.00%+407+9.4%Added
Acadian Asset Management LLC3,653$115.0K0.00%+3,653New
Mirae Asset Global Investments Co., Ltd.2,971$94.2K0.00%+637+27.3%Added
Comerica Bank2,494$79.1K0.00%+1,567+169.0%Added
Nisa Investment Advisors, LLC2,473$78.4K0.00%+191+8.4%Added
KBC Group NV2,121$67.0K0.00%00.0%Unchanged
Van Eck Associates Corp2,076$66.0K0.00%+1,034+99.2%Added
Smartleaf Asset Management LLC1,955$62.9K0.00%+887+83.1%Added
National Bank of Canada1,968$62.3K0.00%+343+21.1%Added
Amalgamated Bank1,880$60.0K0.00%−158−7.8%Reduced
Truvestments Capital LLC1,773$56.2K0.01%+1,109+167.0%Added
Leonteq Securities AG1,500$47.6K0.00%00.0%Unchanged
SBI Securities Co., Ltd.1,400$44.4K0.00%+571+68.9%Added
GF Fund Management Co. Ltd.1,201$38.1K0.00%−98−7.5%Reduced
Strategic Advocates LLC1,067$34.3K0.01%+906+562.7%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.780$25.0K0.00%+241+44.7%Added
Bryn Mawr Trust Co700$22.2K0.00%00.0%Unchanged
Simplex Trading, LLC698$22.1K0.00%+698New
Caitong International Asset Management Co., Ltd626$19.9K0.00%+626New
The PNC Financial Services Group, Inc.505$16.0K0.00%−611−54.7%Reduced
Tower Research Capital LLC (TRC)497$15.8K0.00%−33,790−98.6%Reduced
GAMMA Investing LLC496$15.7K0.00%+239+93.0%Added
Trifecta Capital Advisors, LLC475$15.1K0.00%+475New
Larson Financial Group LLC470$14.9K0.00%+90+23.7%Added
GWM Advisors LLC405$12.8K0.00%+5+1.3%Added
Sterling Capital Management LLC393$12.5K0.00%+250+174.8%Added
Sound Income Strategies, LLC271$11.2K0.00%+271New
Farther Finance Advisors, LLC336$10.6K0.00%−230−40.6%Reduced
Lodestone Wealth Management LLC290$9.20K0.00%+290New
Allworth Financial LP279$8.85K0.00%+21+8.1%Added
Jones Financial Companies LLLP269$8.53K0.00%−66−19.7%Reduced
Essential Partners LLC253$8.03K0.00%+8+3.3%Added
Signaturefd, LLC241$7.64K0.00%−42−14.8%Reduced
Bessemer Group Inc210$7.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.210$7.00K0.00%00.0%Unchanged
Torren Management, LLC217$6.88K0.00%+217New
Align Financial, LLC6,407$6.41K0.00%+6,407New
Blue Bell Private Wealth Management, LLC166$5.27K0.00%00.0%Unchanged
Quadrant Capital Group LLC156$4.95K0.00%00.0%Unchanged
Eastern Bank131$4.16K0.00%+131New