Twist Bioscience Corp

TWST

Exchange: Nasdaq
Industry: Biological Products, (No Diagnostic Substances)
SEC CIK: 0001581280

SEC filings (opens in a new tab)

In the last 90 days, Twist Bioscience Corp insiders filed 0 open-market purchases and 30 sales; 337 institutions reported holding it in 13F filings for Q2 2026, worth $7.85B in total; ARK Invest is the only superinvestor holding it.

Q4 2025 vs. Q3 2025

How the institutions holding Twist Bioscience Corp changed between Q3 2025 and Q4 2025.

All holders in Q4 2025 All holders in Q3 2025

13F holders of TWST: Q3 2025 compared with Q4 2025
Measure	Q3 2025	Of which not filed for Q4 2025	Q4 2025	Change
Holders	239	5	244	+10
Shares	73.8M	110.6K	75.0M	+1.35M (+1.8%)
Value	$2.08B	$3.11M	$2.38B	+$306.8M (+14.8%)

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (48)

Institutions that held Twist Bioscience Corp at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to TWST in Q4 2025
Institution	Shares	Value	% of portfolio
StemPoint Capital LP	518,355	$16.4M	2.82%
Freshford Capital Management, LLC	420,171	$13.3M	5.35%
Blue Water Life Science Advisors, LLC	383,000	$12.1M	7.63%
Osterweis Capital Management Inc	256,878	$8.15M	0.34%
Natixis	103,688	$3.29M	0.01%
Nomura Asset Management International Inc.	80,552	$2.56M	0.00%
HRT Financial LP	73,127	$2.32M	0.01%
Maxi Investments CY Ltd	35,000	$1.11M	0.20%
D. E. Shaw & Co., Inc.	27,581	$874.9K	0.00%
Prelude Capital Management, LLC	22,035	$699.0K	0.05%
Meridiem Capital Partners LP	21,205	$672.6K	0.04%
Odyssean, LLC	18,935	$600.6K	0.43%
Quantinno Capital Management LP	17,675	$560.7K	0.00%
Jump Financial, LLC	16,707	$529.9K	0.01%
Cambridge Investment Research Advisors, Inc.	15,236	$483.0K	0.00%
Quadrature Capital Ltd	14,998	$475.7K	0.00%
Pekin Hardy Strauss, Inc.	14,450	$458.4K	0.04%
Massar Capital Management, LP	12,250	$388.6K	0.08%
Quantbot Technologies LP	10,252	$325.2K	0.01%
Creative Planning	10,211	$323.9K	0.00%
Arrowpoint Investment Partners (Singapore) Pte. Ltd.	9,992	$316.9K	0.05%
Entropy Technologies, LP	9,132	$289.7K	0.02%
Cetera Investment Advisers	8,424	$267.2K	0.00%
VARCOV Co.	8,278	$262.6K	0.10%
Los Angeles Capital Management LLC	7,884	$245.7K	0.00%
Mercer Global Advisors Inc	7,619	$241.7K	0.00%
Axxcess Wealth Management, LLC	6,323	$200.6K	0.00%
Acadian Asset Management LLC	3,653	$115.0K	0.00%
Simplex Trading, LLC	698	$22.1K	0.00%
Caitong International Asset Management Co., Ltd	626	$19.9K	0.00%
Trifecta Capital Advisors, LLC	475	$15.1K	0.00%
Sound Income Strategies, LLC	271	$11.2K	0.00%
Lodestone Wealth Management LLC	290	$9.20K	0.00%
Torren Management, LLC	217	$6.88K	0.00%
Align Financial, LLC	6,407	$6.41K	0.00%
Eastern Bank	131	$4.16K	0.00%
International Assets Investment Management, LLC	127	$4.03K	0.00%
Louisbourg Investments Inc.	95	$3.01K	0.00%
Parkside Financial Bank & Trust	62	$1.97K	0.00%
SHP Wealth Management	28	$888	0.00%
United Financial Planning Group LLC	25	$793	0.00%
ORG Partners LLC	20	$634	0.00%
SageView Advisory Group, LLC	14	$445	0.00%
Pinnacle Wealth Planning Services, Inc.	8	$254	0.00%
Godfrey Financial Associates, Inc.	7	$222	0.00%
Dunhill Financial, LLC	1	$34	0.00%
SJS Investment Consulting Inc.	1	$32	0.00%
Aster Capital Management (DIFC) Ltd	1	$32	0.00%

Sold out (38)

Institutions that held Twist Bioscience Corp at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of TWST in Q4 2025
Institution	Shares, Q3 2025	Value, Q3 2025
Point72 Asset Management, L.P.	530,032	$14.9M
Macquarie Group Ltd	82,248	$2.31M
Man Group plc	76,124	$2.14M
Prosight Management, LP	75,000	$2.11M
Two Sigma Investments, LP	73,755	$2.08M
Voloridge Investment Management, LLC	60,502	$1.70M
Campbell & CO Investment Adviser LLC	47,200	$1.33M
Perbak Capital Partners LLP	46,415	$1.31M
Marshall Wace, LLP	44,066	$1.24M
Engineers Gate Manager LP	40,135	$1.13M
JBF Capital, Inc.	37,100	$1.04M
Tudor Investment Corp Et Al	25,465	$716.6K
Deerfield Management Company, L.P. (Series C)	23,827	$670.5K
First Trust Advisors LP	20,413	$574.4K
Prudential Financial Inc	18,974	$533.9K
Lombard Odier Asset Management (USA) Corp	17,494	$492.3K
Fox Run Management, L.L.C.	15,623	$439.6K
Aigen Investment Management, LP	15,212	$428.1K
Bridgefront Capital, LLC	13,482	$379.4K
Verition Fund Management LLC	12,908	$363.2K
GTS Securities LLC	11,863	$333.8K
STRS Ohio	10,900	$306.7K
DRW Securities, LLC	9,523	$275.6K
Dynamic Technology Lab Private Ltd	9,454	$266.0K
Sherbrooke Park Advisers LLC	8,609	$242.3K
Bayforest Capital Ltd	2,436	$68.5K
Quarry LP	1,000	$28.1K
State of Wyoming	843	$23.7K
Principal Securities, Inc.	593	$16.7K
Advisory Services Network, LLC	402	$11.3K
Optiver Holding B.V.	324	$9.12K
Group One Trading, L.P.	252	$7.09K
Halbert Hargrove Global Advisors, LLC	105	$2.96K
Harbour Investments, Inc.	72	$2.03K
Federation des caisses Desjardins du Quebec	46	$1.29K
Washington Trust Advisors, Inc.	32	$900
Massmutual Trust Co FSB	12	$338
Ronald Blue Trust, Inc.	11	$310

Not filed for Q4 2025 yet (5)

Institutions that held Twist Bioscience Corp at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding TWST in Q3 2025 that haven't filed for Q4 2025
Institution	Shares, Q3 2025	Value, Q3 2025
Cubist Systematic Strategies, LLC	87,518	$2.46M
Point72 (DIFC) Ltd	16,939	$476.7K
Point72 Asia (Singapore) Pte. Ltd.	4,453	$125.3K
Point72 Europe (London) LLP	1,717	$48.3K
Guerra Advisors Inc	20	$563