Spyre Therapeutics, Inc.
SYRE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001636282
In the last 90 days, Spyre Therapeutics, Inc. insiders filed 0 open-market purchases and 9 sales; 265 institutions reported holding it in 13F filings for Q2 2026, worth $8.52B in total; no superinvestor holds it.
Q3 2021 vs. Q2 2021
How the institutions holding Spyre Therapeutics, Inc. changed between Q2 2021 and Q3 2021.
All holders in Q3 2021All holders in Q2 2021
| Measure | Q2 2021 | Of which not filed for Q3 2021 | Q3 2021 | Change |
|---|---|---|---|---|
| Holders | 78 | 1 | 77 | 0 |
| Shares | 41.1M | 2.53M | 40.6M | +2.04M (+5.3%) |
| Value | $285.8M | $17.6M | $322.5M | +$54.3M (+20.2%) |
1 institution that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so the changes leave them out.
New holders (10)
Institutions that held Spyre Therapeutics, Inc. at the end of Q3 2021 but not at the end of Q2 2021.
| Institution | Shares | Value | % of portfolio |
|---|---|---|---|
| Pictet Asset Management SA | 2,532,799 | $20.1M | 0.02% |
| Laurion Capital Management LP | 606,638 | $4.82M | 0.07% |
| SG Americas Securities, LLC | 28,578 | $227.0K | 0.00% |
| MetLife Investment Management | 15,353 | $122.1K | 0.00% |
| HighVista Strategies LLC | 13,137 | $105.0K | 0.07% |
| Metropolitan Life Insurance Co | 11,616 | $92.3K | 0.00% |
| Gsa Capital Partners LLP | 11,242 | $89.0K | 0.01% |
| Susquehanna International Group, LLP | 11,192 | $89.0K | 0.00% |
| Lazard Asset Management LLC | 8,801 | $69.0K | 0.00% |
| Berman Capital Advisors, LLC | 56 | $0 | 0.00% |
Sold out (10)
Institutions that held Spyre Therapeutics, Inc. at the end of Q2 2021 and filed for Q3 2021 without it.
| Institution | Shares, Q2 2021 | Value, Q2 2021 |
|---|---|---|
| Boxer Capital, LLC | 550,000 | $3.83M |
| Point72 Asset Management, L.P. | 469,765 | $3.27M |
| Jacobs Levy Equity Management, Inc | 59,294 | $413.0K |
| Ergoteles LLC | 34,100 | $237.0K |
| California Public Employees Retirement System | 20,841 | $145.0K |
| Cerity Partners LLC | 18,000 | $125.0K |
| Cubist Systematic Strategies, LLC | 11,722 | $82.0K |
| O'Shaughnessy Asset Management, LLC | 1,654 | $12.0K |
| Group One Trading, L.P. | 300 | $2.00K |
| Ellevest, Inc. | 150 | $1.00K |
Not filed for Q3 2021 yet (1)
Institutions that held Spyre Therapeutics, Inc. at the end of Q2 2021 and haven't filed a 13F for Q3 2021. Not filing isn't selling, so they aren't counted as sold out.
| Institution | Shares, Q2 2021 | Value, Q2 2021 |
|---|---|---|
| Pictet Asset Management Ltd | 2,532,799 | $17.6M |