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Synlogic, Inc.

SYBX
Exchange
OTC
Industry
Pharmaceutical Preparations
SEC CIK
0001527599

No open-market purchases or sales by Synlogic, Inc. insiders were filed in the last 90 days; 1 institution reported holding it in 13F filings for Q2 2026, worth $16.7K in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Synlogic, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
51
−1 vs. Q3 2022
Shares held
34.0M
−5.81M (−14.6%) vs. Q3 2022
Total value
$25.8M
−$12.0M (−31.7%) vs. Q3 2022
New holders
8
13 more added
Sold out
9
9 more reduced

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SYBX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 51 institutions
Q1 2021: 55 institutionsQ2 2021: 60 institutionsQ3 2021: 69 institutionsQ4 2021: 62 institutionsQ1 2022: 51 institutionsQ2 2022: 51 institutionsQ3 2022: 52 institutionsQ4 2022: 51 institutionsQ1 2023: 51 institutionsQ2 2023: 45 institutionsQ3 2023: 28 institutionsQ4 2023: 24 institutionsQ1 2024: 17 institutionsQ2 2024: 17 institutionsQ3 2024: 17 institutionsQ4 2024: 18 institutionsQ1 2025: 18 institutionsQ2 2025: 19 institutionsQ3 2025: 23 institutionsQ4 2025: 25 institutionsQ1 2026: 2 institutionsQ2 2026: 1 institution
Value heldQ4 2022: $25.8M
Q1 2021: $65.8MQ2 2021: $114.6MQ3 2021: $133.9MQ4 2021: $104.8MQ1 2022: $102.4MQ2 2022: $46.9MQ3 2022: $37.8MQ4 2022: $25.8MQ1 2023: $21.9MQ2 2023: $13.9MQ3 2023: $7.34MQ4 2023: $18.2MQ1 2024: $12.4MQ2 2024: $10.4MQ3 2024: $10.2MQ4 2024: $9.46MQ1 2025: $8.41MQ2 2025: $8.60MQ3 2025: $11.1MQ4 2025: $7.71MQ1 2026: $14.5KQ2 2026: $16.7K
Institutions holding SYBX and their total value by quarter
QuarterHoldersValue
Q2 20261$16.7K
Q1 20262$14.5K
Q4 202525$7.71M
Q3 202523$11.1M
Q2 202519$8.60M
Q1 202518$8.41M
Q4 202418$9.46M
Q3 202417$10.2M
Q2 202417$10.4M
Q1 202417$12.4M
Q4 202324$18.2M
Q3 202328$7.34M
Q2 202345$13.9M
Q1 202351$21.9M
Q4 202251$25.8M
Q3 202252$37.8M
Q2 202251$46.9M
Q1 202251$102.4M
Q4 202162$104.8M
Q3 202169$133.9M
Q2 202160$114.6M
Q1 202155$65.8M

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Synlogic, Inc.; share changes are against Q3 2022.

Institutions holding SYBX in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC10,577,970$8.04M0.00%+43,600+0.4%Added
OrbiMed Advisors LLC6,029,995$4.58M0.09%00.0%Unchanged
NEA Management Company, LLC4,228,940$3.21M0.18%−4700.0%Reduced
Alyeska Investment Group, L.P.2,702,063$2.05M0.02%−991,613−26.8%Reduced
Atlas Venture Associates IX, LLC2,651,963$2.02M10.03%00.0%Unchanged
Vanguard Group Inc2,243,586$1.71M0.00%+7950.0%Added
Morgan Stanley680,270$517.0K0.00%+620+0.1%Added
Sofinnova Investments, Inc.574,972$437.0K0.03%00.0%Unchanged
LMR Partners LLP515,000$391.4K0.01%00.0%Unchanged
Dimensional Fund Advisors LP471,173$359.0K0.00%00.0%Unchanged
BlackRock Inc.436,922$332.1K0.00%+6,385+1.5%Added
Geode Capital Management, LLC400,006$304.0K0.00%+6,013+1.5%Added
Harbor Capital Advisors, Inc.311,563$236.8K0.23%−6,746−2.1%Reduced
Ikarian Capital, LLC306,757$233.1K0.10%00.0%Unchanged
Bridgeway Capital Management, LLC230,000$174.8K0.00%00.0%Unchanged
ABG Innovation Capital Partners III GP Ltd205,906$156.5K11.95%00.0%Unchanged
State Street Corp154,284$117.3K0.00%00.0%Unchanged
Two Sigma Advisers, LP141,700$107.7K0.00%−10,100−6.7%Reduced
Renaissance Technologies LLC96,400$73.0K0.00%−19,200−16.6%Reduced
Millennium Management LLC95,434$73.0K0.00%+73,422+333.6%Added
Northern Trust Corp93,863$71.3K0.00%00.0%Unchanged
Two Sigma Investments, LP81,952$62.3K0.00%−12,050−12.8%Reduced
Envestnet Asset Management Inc78,671$59.8K0.00%+57,604+273.4%Added
Franklin Resources Inc77,998$59.3K0.00%00.0%Unchanged
PVG Asset Management Corp70,220$53.4K0.24%+51,350+272.1%Added
Nan Fung Group Holdings Ltd68,634$52.2K0.04%00.0%Unchanged
Bank of New York Mellon Corp67,719$51.5K0.00%−458−0.7%Reduced
Acadian Asset Management LLC50,182$37.0K0.00%00.0%Unchanged
Flagship Harbor Advisors, LLC40,000$30.4K0.00%−16,000−28.6%Reduced
Ensign Peak Advisors, Inc33,109$25.2K0.00%00.0%Unchanged
Boothbay Fund Management, LLC30,870$23.5K0.00%00.0%Unchanged
Prudential Financial Inc30,200$23.0K0.00%+30,200New
Charles Schwab Investment Management Inc25,000$19.0K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.22,269$17.0K0.00%+14,223+176.8%Added
UMA Financial Services, Inc.17,302$16.6K0.00%00.0%Unchanged
Tri Locum Partners LP20,961$16.0K0.01%+20,961New
Virtu Financial LLC18,110$14.0K0.00%+18,110New
Jane Street Group, LLC16,411$12.5K0.00%+16,411New
Tower Research Capital LLC (TRC)15,921$12.0K0.00%+8,665+119.4%Added
Cetera Investment Advisers15,414$11.7K0.00%+15,414New
Burney Co15,000$11.4K0.00%00.0%Unchanged
Royal Bank of Canada15,100$11.0K0.00%+4,471+42.1%Added
Soundmark Wealth Management, LLC12,163$9.24K0.01%00.0%Unchanged
Raymond James & Associates12,000$9.12K0.00%00.0%Unchanged
Endurance Wealth Management, Inc.11,900$9.00K0.00%+11,900New
HighTower Advisors, LLC10,000$8.00K0.00%+10,000New
BNP Paribas Arbitrage, SA363$2760.00%00.0%Unchanged
Wells Fargo & Company317$2410.00%+9+2.9%Added
Bank of America Corp116$880.00%+116New
JPMorgan Chase & Co468$00.00%+449+2,363.2%Added
Simplex Trading, LLC139$00.00%−248−64.1%Reduced
Ra Capital Management, L.P.0$00.00%−4,618,415−100.0%Sold out
UBS Oconnor LLC0$00.00%−465,741−100.0%Sold out
Citadel Advisors LLC0$00.00%−14,998−100.0%Sold out
HRT Financial LP0$00.00%−13,198−100.0%Sold out
Tiaa, FSB0$00.00%−12,250−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−11,705−100.0%Sold out
PFS Partners, LLC0$00.00%−2,000−100.0%Sold out
Hazlett, Burt & Watson, Inc.0$00.00%−1,500−100.0%Sold out
Axiom Investment Management LLC0$00.00%−1,500−100.0%Sold out