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Synlogic, Inc.

SYBX
Exchange
OTC
Industry
Pharmaceutical Preparations
SEC CIK
0001527599

No open-market purchases or sales by Synlogic, Inc. insiders were filed in the last 90 days; 1 institution reported holding it in 13F filings for Q2 2026, worth $16.7K in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Synlogic, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
62
−7 vs. Q3 2021
Shares held
43.3M
−574.8K (−1.3%) vs. Q3 2021
Total value
$104.8M
−$29.1M (−21.7%) vs. Q3 2021
New holders
10
16 more added
Sold out
17
13 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SYBX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 62 institutions
Q1 2021: 55 institutionsQ2 2021: 60 institutionsQ3 2021: 69 institutionsQ4 2021: 62 institutionsQ1 2022: 51 institutionsQ2 2022: 51 institutionsQ3 2022: 52 institutionsQ4 2022: 51 institutionsQ1 2023: 51 institutionsQ2 2023: 45 institutionsQ3 2023: 28 institutionsQ4 2023: 24 institutionsQ1 2024: 17 institutionsQ2 2024: 17 institutionsQ3 2024: 17 institutionsQ4 2024: 18 institutionsQ1 2025: 18 institutionsQ2 2025: 19 institutionsQ3 2025: 23 institutionsQ4 2025: 25 institutionsQ1 2026: 2 institutionsQ2 2026: 1 institution
Value heldQ4 2021: $104.8M
Q1 2021: $65.8MQ2 2021: $114.6MQ3 2021: $133.9MQ4 2021: $104.8MQ1 2022: $102.4MQ2 2022: $46.9MQ3 2022: $37.8MQ4 2022: $25.8MQ1 2023: $21.9MQ2 2023: $13.9MQ3 2023: $7.34MQ4 2023: $18.2MQ1 2024: $12.4MQ2 2024: $10.4MQ3 2024: $10.2MQ4 2024: $9.46MQ1 2025: $8.41MQ2 2025: $8.60MQ3 2025: $11.1MQ4 2025: $7.71MQ1 2026: $14.5KQ2 2026: $16.7K
Institutions holding SYBX and their total value by quarter
QuarterHoldersValue
Q2 20261$16.7K
Q1 20262$14.5K
Q4 202525$7.71M
Q3 202523$11.1M
Q2 202519$8.60M
Q1 202518$8.41M
Q4 202418$9.46M
Q3 202417$10.2M
Q2 202417$10.4M
Q1 202417$12.4M
Q4 202324$18.2M
Q3 202328$7.34M
Q2 202345$13.9M
Q1 202351$21.9M
Q4 202251$25.8M
Q3 202252$37.8M
Q2 202251$46.9M
Q1 202251$102.4M
Q4 202162$104.8M
Q3 202169$133.9M
Q2 202160$114.6M
Q1 202155$65.8M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Synlogic, Inc.; share changes are against Q3 2021.

Institutions holding SYBX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC10,456,385$25.3M0.00%+350,084+3.5%Added
Ra Capital Management, L.P.6,666,666$16.1M0.28%00.0%Unchanged
OrbiMed Advisors LLC6,029,995$14.6M0.19%00.0%Unchanged
NEA Management Company, LLC4,229,410$10.2M0.21%00.0%Unchanged
Atlas Venture Associates IX, LLC2,651,963$6.42M2.80%00.0%Unchanged
Alyeska Investment Group, L.P.2,516,706$6.09M0.07%+460,413+22.4%Added
Vanguard Group Inc2,252,000$5.45M0.00%+32,314+1.5%Added
Stonepine Capital Management, LLC1,064,135$2.58M1.18%+64,135+6.4%Added
Opaleye Management Inc.850,000$2.06M0.44%+850,000New
Dimensional Fund Advisors LP632,168$1.53M0.00%−81,721−11.4%Reduced
Sofinnova Investments, Inc.574,972$1.39M0.09%00.0%Unchanged
LMR Partners LLP550,000$1.33M0.02%+50,000+10.0%Added
Ikarian Capital, LLC483,818$1.17M0.34%−305,000−38.7%Reduced
Royce & Associates LP484,041$1.17M0.01%00.0%Unchanged
Harbor Capital Advisors, Inc.437,550$1.06M0.39%+437,550New
BlackRock Inc.401,129$971.0K0.00%+28,170+7.6%Added
Two Sigma Advisers, LP384,200$930.0K0.00%−18,700−4.6%Reduced
Two Sigma Investments, LP346,107$838.0K0.00%−101,543−22.7%Reduced
Geode Capital Management, LLC328,986$796.0K0.00%+20,479+6.6%Added
Millennium Management LLC293,859$711.0K0.00%+192,033+188.6%Added
Bridgeway Capital Management, LLC280,000$678.0K0.01%+100,000+55.6%Added
ABG Innovation Capital Partners III GP Ltd205,906$498.0K28.80%00.0%Unchanged
Susquehanna International Group, LLP132,916$322.0K0.00%+83,329+168.0%Added
Franklin Resources Inc101,443$245.0K0.00%−257−0.3%Reduced
State Street Corp86,256$209.0K0.00%00.0%Unchanged
Triumph Capital Management83,592$202.0K0.09%+83,592New
Northern Trust Corp77,159$187.0K0.00%+10,224+15.3%Added
Acadian Asset Management LLC77,655$186.0K0.00%+68,991+796.3%Added
Flagship Harbor Advisors, LLC69,000$167.0K0.02%00.0%Unchanged
Bank of New York Mellon Corp68,580$166.0K0.00%00.0%Unchanged
Nan Fung Group Holdings Ltd68,634$166.0K0.05%00.0%Unchanged
Renaissance Technologies LLC54,700$132.0K0.00%−133,972−71.0%Reduced
Morgan Stanley49,902$121.0K0.00%−26,255−34.5%Reduced
Boothbay Fund Management, LLC46,712$113.0K0.00%−97,740−67.7%Reduced
Jump Financial, LLC37,700$91.0K0.01%+37,700New
Connor, Clark & Lunn Investment Management Ltd.32,161$78.0K0.00%+32,161New
Charles Schwab Investment Management Inc25,000$61.0K0.00%+25,000New
Jacobs Levy Equity Management, Inc18,973$46.0K0.00%−77,018−80.2%Reduced
Tower Research Capital LLC (TRC)17,612$43.0K0.00%+15,341+675.5%Added
Envestnet Asset Management Inc16,081$39.0K0.00%+965+6.4%Added
Burney Co15,000$36.0K0.00%+15,000New
Parametric Portfolio Associates LLC12,885$31.0K0.00%−13,567−51.3%Reduced
Citadel Advisors LLC11,293$27.0K0.00%−736−6.1%Reduced
Raymond James & Associates11,000$27.0K0.00%00.0%Unchanged
Janney Montgomery Scott LLC11,000$27.0K0.00%00.0%Unchanged
Bank of America Corp10,867$26.0K0.00%+9,443+663.1%Added
ExodusPoint Capital Management, LP10,924$26.0K0.00%+10,924New
Soundmark Wealth Management, LLC10,000$24.0K0.02%00.0%Unchanged
Bank Julius Baer & Co. Ltd, Zurich8,000$19.0K0.00%00.0%Unchanged
Group One Trading, L.P.5,875$14.0K0.00%−3,401−36.7%Reduced
Evoke Wealth, LLC5,591$14.0K0.00%00.0%Unchanged
Endurance Wealth Management, Inc.4,900$12.0K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.4,868$12.0K0.00%00.0%Unchanged
Simplex Trading, LLC4,893$11.0K0.00%+4,893New
Total Clarity Wealth Management, Inc.1,000$2.00K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA502$1.22K0.00%00.0%Unchanged
Wells Fargo & Company316$1.00K0.00%+101+47.0%Added
Federated Hermes, Inc.232$1.00K0.00%−122−34.5%Reduced
Captrust Financial Advisors239$1.00K0.00%00.0%Unchanged
High Net Worth Advisory Group LLC500$1.00K0.00%+500New
JPMorgan Chase & Co19$00.00%00.0%Unchanged
Versant Capital Management, Inc121$00.00%00.0%Unchanged
Logos Global Management LP0$00.00%−1,500,000−100.0%Sold out
Maven Securities LTD0$00.00%−416,943−100.0%Sold out
Gilder Gagnon Howe & Co LLC0$00.00%−165,909−100.0%Sold out
Monashee Investment Management LLC0$00.00%−150,000−100.0%Sold out
Walleye Capital LLC0$00.00%−98,500−100.0%Sold out
Laurion Capital Management LP0$00.00%−80,100−100.0%Sold out
Suvretta Capital Management, LLC0$00.00%−60,000−100.0%Sold out
Archford Capital Strategies, LLC0$00.00%−50,000−100.0%Sold out
Caas Capital Management LP0$00.00%−50,000−100.0%Sold out
Squarepoint Ops LLC0$00.00%−38,116−100.0%Sold out
Magnetar Financial LLC0$00.00%−32,881−100.0%Sold out
Virtu Financial LLC0$00.00%−27,559−100.0%Sold out
XTX Topco Ltd0$00.00%−13,289−100.0%Sold out
Barclays PLC0$00.00%−8,374−100.0%Sold out
UBS Group AG0$00.00%−3,908−100.0%Sold out
Harbour Investments, Inc.0$00.00%−1,690−100.0%Sold out
Cutler Group LP0$00.00%−800−100.0%Sold out