Spero Therapeutics, Inc.
SPRO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001701108
No open-market purchases or sales by Spero Therapeutics, Inc. insiders were filed in the last 90 days; 59 institutions reported holding it in 13F filings for Q2 2026, worth $47.5M in total; no superinvestor holds it.
Q1 2025 vs. Q4 2024
How the institutions holding Spero Therapeutics, Inc. changed between Q4 2024 and Q1 2025.
All holders in Q1 2025All holders in Q4 2024
| Measure | Q4 2024 | Of which not filed for Q1 2025 | Q1 2025 | Change |
|---|---|---|---|---|
| Holders | 50 | 1 | 38 | −11 |
| Shares | 15.7M | 2.60K | 15.1M | −569.4K (−3.6%) |
| Value | $16.1M | $2.68K | $10.9M | −$5.27M (−32.6%) |
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so the changes leave them out.
New holders (1)
Institutions that held Spero Therapeutics, Inc. at the end of Q1 2025 but not at the end of Q4 2024.
| Institution | Shares | Value | % of portfolio |
|---|---|---|---|
| EP Wealth Advisors, LLC | 16,500 | $11.9K | 0.00% |
Sold out (12)
Institutions that held Spero Therapeutics, Inc. at the end of Q4 2024 and filed for Q1 2025 without it.
| Institution | Shares, Q4 2024 | Value, Q4 2024 |
|---|---|---|
| Jane Street Group, LLC | 52,869 | $54.5K |
| Virtu Financial LLC | 46,046 | $47.0K |
| XTX Topco Ltd | 30,138 | $31.0K |
| Susquehanna International Group, LLP | 29,755 | $30.6K |
| PFG Investments, LLC | 24,534 | $25.3K |
| HRT Financial LP | 14,692 | $15.0K |
| Dimensional Fund Advisors LP | 10,003 | $10.3K |
| National Bank of Canada | 10,000 | $10.3K |
| Tower Research Capital LLC (TRC) | 929 | $957 |
| Advisor Group Holdings, Inc. | 295 | $304 |
| Richards, Merrill & Peterson, Inc. | 150 | $155 |
| Federation des caisses Desjardins du Quebec | 30 | $31 |
Not filed for Q1 2025 yet (1)
Institutions that held Spero Therapeutics, Inc. at the end of Q4 2024 and haven't filed a 13F for Q1 2025. Not filing isn't selling, so they aren't counted as sold out.
| Institution | Shares, Q4 2024 | Value, Q4 2024 |
|---|---|---|
| WR Wealth Planners, LLC | 2,600 | $2.68K |