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Summit Therapeutics Inc.

SMMT
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001599298

No open-market purchases or sales by Summit Therapeutics Inc. insiders were filed in the last 90 days; 242 institutions reported holding it in 13F filings for Q2 2026, worth $1.98B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Summit Therapeutics Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
206
−25 vs. Q3 2025
Shares held
117.8M
+14.9M (+14.5%) vs. Q3 2025
Total value
$2.06B
−$66.0M (−3.1%) vs. Q3 2025
New holders
35
75 more added
Sold out
60
65 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SMMT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 206 institutions
Q1 2021: 38 institutionsQ2 2021: 54 institutionsQ3 2021: 51 institutionsQ4 2021: 52 institutionsQ1 2022: 48 institutionsQ2 2022: 41 institutionsQ3 2022: 42 institutionsQ4 2022: 57 institutionsQ1 2023: 86 institutionsQ2 2023: 96 institutionsQ3 2023: 91 institutionsQ4 2023: 95 institutionsQ1 2024: 103 institutionsQ2 2024: 121 institutionsQ3 2024: 164 institutionsQ4 2024: 196 institutionsQ1 2025: 202 institutionsQ2 2025: 226 institutionsQ3 2025: 232 institutionsQ4 2025: 206 institutionsQ1 2026: 222 institutionsQ2 2026: 242 institutions
Value heldQ4 2025: $2.06B
Q1 2021: $54.5MQ2 2021: $82.4MQ3 2021: $55.3MQ4 2021: $30.0MQ1 2022: $27.4MQ2 2022: $8.46MQ3 2022: $3.78MQ4 2022: $34.5MQ1 2023: $37.0MQ2 2023: $87.6MQ3 2023: $60.4MQ4 2023: $84.4MQ1 2024: $205.5MQ2 2024: $563.0MQ3 2024: $1.85BQ4 2024: $1.65BQ1 2025: $1.91BQ2 2025: $2.08BQ3 2025: $2.13BQ4 2025: $2.06BQ1 2026: $2.25BQ2 2026: $1.98B
Institutions holding SMMT and their total value by quarter
QuarterHoldersValue
Q2 2026242$1.98B
Q1 2026222$2.25B
Q4 2025206$2.06B
Q3 2025232$2.13B
Q2 2025226$2.08B
Q1 2025202$1.91B
Q4 2024196$1.65B
Q3 2024164$1.85B
Q2 2024121$563.0M
Q1 2024103$205.5M
Q4 202395$84.4M
Q3 202391$60.4M
Q2 202396$87.6M
Q1 202386$37.0M
Q4 202257$34.5M
Q3 202242$3.78M
Q2 202241$8.46M
Q1 202248$27.4M
Q4 202152$30.0M
Q3 202151$55.3M
Q2 202154$82.4M
Q1 202138$54.5M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Summit Therapeutics Inc.; share changes are against Q3 2025.

Institutions holding SMMT in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
CIBC Asset Management Inc24,289$424.8K0.00%+2,166+9.8%Added
Steward Partners Investment Advisory, LLC23,045$403.1K0.00%+3,133+15.7%Added
Wealth Enhancement Advisory Services, LLC20,875$389.5K0.00%+4,464+27.2%Added
Allianz Asset Management GmbH22,200$388.3K0.00%00.0%Unchanged
Cynosure Management, LLC22,070$386.0K0.04%+3,461+18.6%Added
Alliancebernstein L.P.20,606$360.4K0.00%+383+1.9%Added
Vance Wealth, Inc.19,983$349.5K0.10%+79+0.4%Added
Q3 Asset Management19,567$342.0K0.08%00.0%Unchanged
Raymond James Financial Inc17,851$312.2K0.00%+3,743+26.5%Added
Xponance, Inc.17,503$306.1K0.00%+460+2.7%Added
Russell Investments Group, Ltd.16,966$296.7K0.00%−41,133−70.8%Reduced
Mirae Asset Global ETFs Holdings Ltd.16,860$294.9K0.00%−1,136−6.3%Reduced
Qsemble Capital Management, LP16,419$287.2K0.02%−879−5.1%Reduced
Gotham Asset Management, LLC15,727$275.1K0.00%00.0%Unchanged
SG Americas Securities, LLC15,589$273.0K0.00%+10,472+204.7%Added
Campbell & CO Investment Adviser LLC15,407$269.5K0.01%+15,407New
Virtus Investment Advisers, Inc.15,141$264.8K0.07%+9,497+168.3%Added
GF Fund Management Co. Ltd.14,629$255.9K0.00%−1,353−8.5%Reduced
Quantinno Capital Management LP14,323$250.5K0.00%+14,323New
Bellevue Group AG14,262$249.4K0.00%−4,720−24.9%Reduced
LPL Financial LLC13,160$230.2K0.00%−9,633−42.3%Reduced
Three Seasons Wealth, LLC12,869$225.1K0.02%00.0%Unchanged
Creative Planning12,811$224.1K0.00%−2,679−17.3%Reduced
Blankinship & Foster, LLC12,777$223.5K0.05%00.0%Unchanged
U.S. Capital Wealth Advisors, LLC12,000$209.9K0.01%00.0%Unchanged
Machina Capital S.A.S.11,636$203.5K0.04%+11,636New
State of Wyoming11,533$201.7K0.02%+11,533New
Hudson Bay Capital Management LP11,440$200.1K0.00%+11,440New
Advisors Asset Management, Inc.11,125$194.6K0.00%−50.0%Reduced
Evoke Wealth, LLC11,052$193.3K0.00%−2,339−17.5%Reduced
Two Sigma Advisers, LP10,700$187.1K0.00%+10,700New
Willis Investment Counsel10,390$181.7K0.01%+390+3.9%Added
SEI Investments Co10,063$176.0K0.00%−17,100−63.0%Reduced
Sargent Investment Group, LLC10,000$174.9K0.02%00.0%Unchanged
Amalgamated Bank9,465$166.0K0.00%+913+10.7%Added
Federation des caisses Desjardins du Quebec8,613$150.6K0.00%−690−7.4%Reduced
MetLife Investment Management7,544$131.9K0.00%+66+0.9%Added
California State Teachers Retirement System7,270$127.2K0.00%−103−1.4%Reduced
Havemeyer Place LP6,254$109.4K0.02%+6,254New
Quest Partners LLC6,188$108.2K0.01%−13,108−67.9%Reduced
Advisor Group Holdings, Inc.5,281$92.4K0.00%−212−3.9%Reduced
Osterweis Capital Management Inc5,000$87.5K0.00%00.0%Unchanged
IFP Advisors, Inc4,429$77.5K0.00%00.0%Unchanged
Royal Bank of Canada3,196$56.0K0.00%−182,617−98.3%Reduced
Fifth Third Bancorp3,000$52.5K0.00%00.0%Unchanged
STRS Ohio2,798$48.9K0.00%+5+0.2%Added
Truvestments Capital LLC2,603$45.5K0.01%+1,736+200.2%Added
Adirondack Trust Co2,500$43.7K0.01%00.0%Unchanged
Daiwa Securities Group Inc.2,157$38.0K0.00%−10,507−83.0%Reduced
T. Rowe Price Investment Management, Inc.1,873$33.0K0.00%+1,805+2,654.4%Added
Larson Financial Group LLC1,823$31.9K0.00%+108+6.3%Added
National Bank of Canada1,695$29.6K0.00%+931+121.9%Added
Kestra Advisory Services, LLC1,622$28.4K0.00%+1,622New
Sound Income Strategies, LLC1,005$17.1K0.00%00.0%Unchanged
Bessemer Group Inc1,015$17.0K0.00%+880+651.9%Added
Sterling Capital Management LLC836$14.6K0.00%+659+372.3%Added
Golden State Wealth Management, LLC828$14.5K0.00%00.0%Unchanged
GAMMA Investing LLC805$14.1K0.00%−173−17.7%Reduced
Covestor Ltd658$12.0K0.01%00.0%Unchanged
Smartleaf Asset Management LLC635$11.1K0.00%+64+11.2%Added
Jones Financial Companies LLLP548$9.59K0.00%+114+26.3%Added
Vermillion Wealth Management, Inc.504$8.81K0.00%00.0%Unchanged
Rosenberg Matthew Hamilton501$8.76K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.489$8.55K0.00%−1,301−72.7%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)424$7.42K0.00%00.0%Unchanged
US Bancorp325$5.68K0.00%−356−52.3%Reduced
SBI Securities Co., Ltd.289$5.05K0.00%+81+38.9%Added
WPG Advisers, LLC288$5.04K0.00%+288New
CWM, LLC295$5.00K0.00%+172+139.8%Added
Nisa Investment Advisors, LLC237$4.14K0.00%−64−21.3%Reduced
AdvisorNet Financial, Inc228$3.99K0.00%+228New
Gunpowder Capital Management, LLC dba Oliver Wealth Management200$3.50K0.00%+200New
EverSource Wealth Advisors, LLC139$2.43K0.00%+40+40.4%Added
SRS Capital Advisors, Inc.94$1.64K0.00%−12−11.3%Reduced
Toth Financial Advisory Corp90$1.57K0.00%+90New
J.Safra Asset Management Corp83$1.45K0.00%00.0%Unchanged
Signaturefd, LLC78$1.36K0.00%−74−48.7%Reduced
TD Private Client Wealth LLC74$1.29K0.00%00.0%Unchanged
Allworth Financial LP69$1.21K0.00%−288−80.7%Reduced
Harbour Investments, Inc.57$9970.00%−284−83.3%Reduced
UMA Financial Services, Inc.55$9620.00%00.0%Unchanged
Parallel Advisors, LLC50$8750.00%−1,814−97.3%Reduced
Litman Gregory Asset Management LLC50$8750.00%+50New
Assetmark, Inc44$7700.00%−29,822−99.9%Reduced
CVA Family Office, LLC40$7000.00%00.0%Unchanged
ORG Partners LLC40$6990.00%00.0%Unchanged
Comerica Bank32$5600.00%−732−95.8%Reduced
Rialto Wealth Management, LLC29$5080.00%+29New
Marquette Asset Management, LLC28$4900.00%+28New
United Financial Planning Group LLC20$3500.00%+20New
JFS Wealth Advisors, LLC13$2280.00%−22−62.9%Reduced
Versant Capital Management, Inc10$1750.00%+10New
SHP Wealth Management10$1750.00%+10New
Hughes Financial Services, LLC7$1220.00%+7New
True Wealth Design, LLC6$1050.00%−1−14.3%Reduced
Transamerica Financial Advisors, Inc.6$1050.00%+2+50.0%Added
Stone House Investment Management, LLC6$1050.00%+6New
Rakuten Securities, Inc.5$870.00%00.0%Unchanged
CIBC Private Wealth Group, LLC3$520.00%+3New
Root Financial Partners, LLC2$350.00%−34−94.4%Reduced