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Summit Therapeutics Inc.

SMMT
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001599298

No open-market purchases or sales by Summit Therapeutics Inc. insiders were filed in the last 90 days; 242 institutions reported holding it in 13F filings for Q2 2026, worth $1.98B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Summit Therapeutics Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
232
+10 vs. Q2 2025
Shares held
102.9M
+6.43M (+6.7%) vs. Q2 2025
Total value
$2.13B
+$76.2M (+3.7%) vs. Q2 2025
New holders
51
77 more added
Sold out
41
68 more reduced

4 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SMMT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 232 institutions
Q1 2021: 38 institutionsQ2 2021: 54 institutionsQ3 2021: 51 institutionsQ4 2021: 52 institutionsQ1 2022: 48 institutionsQ2 2022: 41 institutionsQ3 2022: 42 institutionsQ4 2022: 57 institutionsQ1 2023: 86 institutionsQ2 2023: 96 institutionsQ3 2023: 91 institutionsQ4 2023: 95 institutionsQ1 2024: 103 institutionsQ2 2024: 121 institutionsQ3 2024: 164 institutionsQ4 2024: 196 institutionsQ1 2025: 202 institutionsQ2 2025: 226 institutionsQ3 2025: 232 institutionsQ4 2025: 206 institutionsQ1 2026: 222 institutionsQ2 2026: 242 institutions
Value heldQ3 2025: $2.13B
Q1 2021: $54.5MQ2 2021: $82.4MQ3 2021: $55.3MQ4 2021: $30.0MQ1 2022: $27.4MQ2 2022: $8.46MQ3 2022: $3.78MQ4 2022: $34.5MQ1 2023: $37.0MQ2 2023: $87.6MQ3 2023: $60.4MQ4 2023: $84.4MQ1 2024: $205.5MQ2 2024: $563.0MQ3 2024: $1.85BQ4 2024: $1.65BQ1 2025: $1.91BQ2 2025: $2.08BQ3 2025: $2.13BQ4 2025: $2.06BQ1 2026: $2.25BQ2 2026: $1.98B
Institutions holding SMMT and their total value by quarter
QuarterHoldersValue
Q2 2026242$1.98B
Q1 2026222$2.25B
Q4 2025206$2.06B
Q3 2025232$2.13B
Q2 2025226$2.08B
Q1 2025202$1.91B
Q4 2024196$1.65B
Q3 2024164$1.85B
Q2 2024121$563.0M
Q1 2024103$205.5M
Q4 202395$84.4M
Q3 202391$60.4M
Q2 202396$87.6M
Q1 202386$37.0M
Q4 202257$34.5M
Q3 202242$3.78M
Q2 202241$8.46M
Q1 202248$27.4M
Q4 202152$30.0M
Q3 202151$55.3M
Q2 202154$82.4M
Q1 202138$54.5M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Summit Therapeutics Inc.; share changes are against Q2 2025.

Institutions holding SMMT in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Baker Bros. Advisors LP33,722,974$696.7M5.03%00.0%Unchanged
Vanguard Group Inc11,379,728$235.1M0.00%+2,706,056+31.2%Added
FMR LLC8,917,887$184.2M0.01%−308,489−3.3%Reduced
BlackRock, Inc.7,363,793$152.1M0.00%+517,126+7.6%Added
State Street Corp6,361,936$131.4M0.00%+2,344,239+58.3%Added
Price T Rowe Associates Inc4,538,823$93.8M0.01%+633,675+16.2%Added
Geode Capital Management, LLC3,132,735$64.7M0.00%+197,920+6.7%Added
Morgan Stanley1,926,828$39.8M0.00%+1,284,827+200.1%Added
Pictet Asset Management Holding SA1,604,163$33.5M0.03%−559,710−25.9%Reduced
Apeiron Capital Ltd1,310,941$27.1M12.87%+110,000+9.2%Added
UBS Group AG1,278,783$26.4M0.01%−815,175−38.9%Reduced
Standard Life Aberdeen plc1,139,530$23.5M0.04%00.0%Unchanged
Nomura Holdings Inc1,048,927$21.7M0.10%+1,004,971+2,286.3%Added
Charles Schwab Investment Management Inc876,390$18.1M0.00%−415,281−32.2%Reduced
Polymer Capital Management (HK) LTD817,276$16.9M2.35%−72,753−8.2%Reduced
Fiera Capital Corp762,094$15.7M0.05%−20,753−2.7%Reduced
Polar Capital Holdings Plc746,393$15.4M0.07%−253,607−25.4%Reduced
Rock Springs Capital Management LP710,000$14.7M0.86%00.0%Unchanged
Bank of America Corp657,313$13.6M0.00%+91,166+16.1%Added
Tang Capital Management LLC550,000$11.4M0.44%+300,000+120.0%Added
Northern Trust Corp546,262$11.3M0.00%+14,634+2.8%Added
TD Asset Management Inc537,530$11.1M0.01%+53,520+11.1%Added
Candriam Luxembourg S.C.A.513,763$10.6M0.06%00.0%Unchanged
Goldman Sachs Group Inc497,547$10.3M0.00%+194,121+64.0%Added
Capricorn Fund Managers Ltd496,266$10.3M3.44%+496,266New
Barclays PLC475,777$9.83M0.00%+161,953+51.6%Added
Invesco Ltd.426,075$8.80M0.00%+2,048+0.5%Added
Dimensional Fund Advisors LP374,583$7.74M0.00%−5,421−1.4%Reduced
Bank of New York Mellon Corp367,126$7.58M0.00%+23,602+6.9%Added
QVT Financial LP360,524$7.45M0.83%00.0%Unchanged
Tudor Investment Corp Et Al347,241$7.17M0.05%+347,241New
Rafferty Asset Management, LLC339,176$7.01M0.02%+140,323+70.6%Added
Skandinaviska Enskilda Banken AB (publ)338,363$6.99M0.03%+271,912+409.2%Added
Sculptor Capital LP333,500$6.89M0.09%+333,500New
Manufacturers Life Insurance Company, The299,546$6.19M0.01%+35,905+13.6%Added
Deutsche Bank AG269,884$5.58M0.00%+2,096+0.8%Added
New York State Common Retirement Fund264,290$5.46M0.01%+7,400+2.9%Added
Schroder Investment Management Group242,619$5.13M0.00%+98,112+67.9%Added
Susquehanna International Group, LLP246,562$5.09M0.01%−53,411−17.8%Reduced
Nuveen, LLC232,642$4.81M0.00%+52,193+28.9%Added
Woodline Partners LP214,507$4.43M0.02%+32,495+17.9%Added
Citadel Advisors LLC202,712$4.19M0.00%+100,295+97.9%Added
Voya Investment Management LLC202,618$4.19M0.00%−3,081−1.5%Reduced
Superstring Capital Management LP197,253$4.08M4.01%+197,253New
Balyasny Asset Management LLC194,851$4.03M0.01%+194,851New
Wells Fargo & Company192,876$3.98M0.00%−41,844−17.8%Reduced
AQR Capital Management LLC187,484$3.87M0.00%+165,172+740.3%Added
Royal Bank of Canada185,813$3.84M0.00%+99,319+114.8%Added
First Trust Advisors LP171,524$3.54M0.00%+171,524New
Verition Fund Management LLC165,602$3.42M0.02%−16,381−9.0%Reduced
Citigroup Inc159,873$3.30M0.00%+46,535+41.1%Added
Griffin Asset Management, Inc.140,282$2.90M0.33%+20,900+17.5%Added
JPMorgan Chase & Co136,626$2.82M0.00%−69,481−33.7%Reduced
D. E. Shaw & Co., Inc.130,627$2.70M0.00%−6,818−5.0%Reduced
China Universal Asset Management Co., Ltd.130,210$2.69M0.22%−18,952−12.7%Reduced
Rhumbline Advisers122,922$2.54M0.00%+528+0.4%Added
Millennium Management LLC120,514$2.49M0.00%−435,495−78.3%Reduced
Cerity Partners LLC114,657$2.37M0.00%−187−0.2%Reduced
Dark Forest Capital Management LP112,199$2.32M0.09%+112,199New
Squarepoint Ops LLC109,826$2.27M0.00%−181,396−62.3%Reduced
ADAR1 Capital Management, LLC102,969$2.13M0.21%+90,969+758.1%Added
Yong Rong (HK) Asset Management Ltd100,000$2.07M0.43%+100,000New
HealthInvest Partners AB92,737$2.03M0.75%00.0%Unchanged
Bank of Montreal98,018$2.03M0.00%−2,502−2.5%Reduced
State Board of Administration of Florida Retirement System96,009$1.98M0.00%−1,493−1.5%Reduced
Envestnet Asset Management Inc92,538$1.91M0.00%−2,012−2.1%Reduced
State of Wisconsin Investment Board91,835$1.90M0.00%+91,835New
Colony Group, LLC88,419$1.83M0.00%+1,979+2.3%Added
NEOS Investment Management LLC80,284$1.66M0.01%−26,659−24.9%Reduced
Tema ETFs LLC80,284$1.66M0.14%−26,659−24.9%Reduced
UBS Asset Management Americas Inc79,589$1.64M0.00%−7,300−8.4%Reduced
Mariner, LLC79,572$1.64M0.00%+67,810+576.5%Added
Polianta Ltd74,700$1.54M0.64%+14,100+23.3%Added
Wealth Management Partners, LLC74,570$1.54M0.49%−1,042−1.4%Reduced
Capital Fund Management S.A.74,153$1.53M0.02%+74,153New
Sectoral Asset Management Inc74,070$1.53M0.94%+8,850+13.6%Added
Profund Advisors LLC69,933$1.44M0.05%+30,293+76.4%Added
Illinois Municipal Retirement Fund68,673$1.42M0.02%+37,611+121.1%Added
Winton Group Ltd64,900$1.34M0.05%+64,900New
Perseverance Asset Management International59,745$1.23M0.21%−80,183−57.3%Reduced
Russell Investments Group, Ltd.58,099$1.20M0.00%−145,779−71.5%Reduced
Farther Finance Advisors, LLC55,236$1.14M0.02%+55,236New
Ameriprise Financial Inc53,512$1.11M0.00%+20,685+63.0%Added
Treasurer of the State of North Carolina52,519$1.08M0.00%−2,041−3.7%Reduced
Police & Firemen's Retirement System of New Jersey52,505$1.08M0.01%+7,917+17.8%Added
Guggenheim Capital LLC40,997$847.0K0.01%+6,538+19.0%Added
Verde Servicos Internacionais S.A.40,000$826.0K0.24%+40,000New
Levin Capital Strategies, L.P.36,676$757.7K0.07%+500+1.4%Added
Vident Advisory, LLC36,646$757.1K0.01%−2,510−6.4%Reduced
Public Employees Retirement System of Ohio36,492$753.9K0.00%+227+0.6%Added
Beacon Pointe Advisors, LLC35,726$738.1K0.01%+35,726New
Handelsbanken Fonder AB34,200$707.0K0.00%00.0%Unchanged
DnB Asset Management AS30,923$638.9K0.00%−1,354−4.2%Reduced
Mirae Asset Global Investments Co., Ltd.30,588$631.9K0.00%+40+0.1%Added
Group One Trading, L.P.30,250$625.0K0.02%+30,250New
Assetmark, Inc29,866$617.0K0.00%−1,218−3.9%Reduced
Man Group plc29,550$610.5K0.00%−10,857−26.9%Reduced
BNP Paribas Arbitrage, SA29,176$602.8K0.00%−668−2.2%Reduced
Caption Management, LLC28,264$583.9K0.03%−238,991−89.4%Reduced
SEI Investments Co27,163$561.2K0.00%+860+3.3%Added