Summit Therapeutics Inc.
SMMT- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001599298
No open-market purchases or sales by Summit Therapeutics Inc. insiders were filed in the last 90 days; 242 institutions reported holding it in 13F filings for Q2 2026, worth $1.98B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Summit Therapeutics Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 206
- −25 vs. Q3 2025
- Shares held
- 117.8M
- +14.9M (+14.5%) vs. Q3 2025
- Total value
- $2.06B
- −$66.0M (−3.1%) vs. Q3 2025
- New holders
- 35
- 75 more added
- Sold out
- 60
- 65 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SMMT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 242 | $1.98B |
| Q1 2026 | 222 | $2.25B |
| Q4 2025 | 206 | $2.06B |
| Q3 2025 | 232 | $2.13B |
| Q2 2025 | 226 | $2.08B |
| Q1 2025 | 202 | $1.91B |
| Q4 2024 | 196 | $1.65B |
| Q3 2024 | 164 | $1.85B |
| Q2 2024 | 121 | $563.0M |
| Q1 2024 | 103 | $205.5M |
| Q4 2023 | 95 | $84.4M |
| Q3 2023 | 91 | $60.4M |
| Q2 2023 | 96 | $87.6M |
| Q1 2023 | 86 | $37.0M |
| Q4 2022 | 57 | $34.5M |
| Q3 2022 | 42 | $3.78M |
| Q2 2022 | 41 | $8.46M |
| Q1 2022 | 48 | $27.4M |
| Q4 2021 | 52 | $30.0M |
| Q3 2021 | 51 | $55.3M |
| Q2 2021 | 54 | $82.4M |
| Q1 2021 | 38 | $54.5M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Summit Therapeutics Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baker Bros. Advisors LP | 36,391,063 | $636.5M | 3.73% | +2,668,089+7.9% | Added |
| FMR LLC | 13,360,807 | $233.7M | 0.01% | +4,442,920+49.8% | Added |
| Vanguard Group Inc | 11,177,220 | $195.5M | 0.00% | −202,508−1.8% | Reduced |
| Price T Rowe Associates Inc | 9,371,415 | $163.9M | 0.02% | +4,832,592+106.5% | Added |
| BlackRock, Inc. | 9,361,921 | $163.7M | 0.00% | +1,998,128+27.1% | Added |
| State Street Corp | 6,636,361 | $116.1M | 0.00% | +274,425+4.3% | Added |
| Geode Capital Management, LLC | 3,147,480 | $55.1M | 0.00% | +14,745+0.5% | Added |
| Citadel Advisors LLC | 2,475,708 | $43.3M | 0.03% | +2,272,996+1,121.3% | Added |
| Polymer Capital Management (HK) LTD | 1,421,155 | $24.9M | 3.87% | +603,879+73.9% | Added |
| Pictet Asset Management Holding SA | 1,383,775 | $24.4M | 0.02% | −220,388−13.7% | Reduced |
| Norges Bank | 1,373,943 | $24.0M | 0.00% | +1,373,943 | New |
| Apeiron Capital Ltd | 1,309,241 | $22.9M | 26.48% | −1,700−0.1% | Reduced |
| TD Asset Management Inc | 1,205,272 | $21.1M | 0.02% | +667,742+124.2% | Added |
| Standard Life Aberdeen plc | 927,171 | $16.2M | 0.03% | −212,359−18.6% | Reduced |
| Morgan Stanley | 926,579 | $16.2M | 0.00% | −1,000,249−51.9% | Reduced |
| Charles Schwab Investment Management Inc | 892,629 | $15.6M | 0.00% | +16,239+1.9% | Added |
| UBS Group AG | 870,719 | $15.2M | 0.00% | −408,064−31.9% | Reduced |
| Squarepoint Ops LLC | 715,410 | $12.5M | 0.03% | +605,584+551.4% | Added |
| Rock Springs Capital Management LP | 710,000 | $12.4M | 0.64% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 578,248 | $10.1M | 0.02% | +553,218+2,210.2% | Added |
| Nomura Holdings Inc | 542,234 | $9.48M | 0.03% | −506,693−48.3% | Reduced |
| Candriam Luxembourg S.C.A. | 540,662 | $9.46M | 0.05% | +26,899+5.2% | Added |
| Northern Trust Corp | 528,487 | $9.24M | 0.00% | −17,775−3.3% | Reduced |
| Goldman Sachs Group Inc | 485,566 | $8.49M | 0.00% | −11,981−2.4% | Reduced |
| Bank of America Corp | 477,393 | $8.35M | 0.00% | −179,920−27.4% | Reduced |
| Millennium Management LLC | 469,017 | $8.20M | 0.01% | +348,503+289.2% | Added |
| Invesco Ltd. | 461,301 | $8.07M | 0.00% | +35,226+8.3% | Added |
| Manufacturers Life Insurance Company, The | 440,953 | $7.71M | 0.01% | +141,407+47.2% | Added |
| Tudor Investment Corp Et Al | 423,084 | $7.40M | 0.04% | +75,843+21.8% | Added |
| D. E. Shaw & Co., Inc. | 415,284 | $7.26M | 0.01% | +284,657+217.9% | Added |
| Dimensional Fund Advisors LP | 376,563 | $6.59M | 0.00% | +1,980+0.5% | Added |
| QVT Financial LP | 360,524 | $6.31M | 0.60% | 00.0% | Unchanged |
| Sculptor Capital LP | 356,900 | $6.24M | 0.07% | +23,400+7.0% | Added |
| AQR Capital Management LLC | 357,870 | $6.19M | 0.00% | +170,386+90.9% | Added |
| Bank of New York Mellon Corp | 353,756 | $6.19M | 0.00% | −13,370−3.6% | Reduced |
| Barclays PLC | 338,390 | $5.92M | 0.00% | −137,387−28.9% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 338,363 | $5.91M | 0.02% | 00.0% | Unchanged |
| Readystate Asset Management LP | 306,184 | $5.36M | 0.24% | +306,184 | New |
| Rafferty Asset Management, LLC | 287,810 | $5.03M | 0.02% | −51,366−15.1% | Reduced |
| Schroder Investment Management Group | 251,391 | $4.40M | 0.00% | +8,772+3.6% | Added |
| Deutsche Bank AG | 237,788 | $4.16M | 0.00% | −32,096−11.9% | Reduced |
| Nuveen, LLC | 232,642 | $4.07M | 0.00% | 00.0% | Unchanged |
| Verition Fund Management LLC | 228,990 | $4.01M | 0.02% | +63,388+38.3% | Added |
| Woodline Partners LP | 214,507 | $3.75M | 0.01% | 00.0% | Unchanged |
| Griffin Asset Management, Inc. | 195,547 | $3.42M | 0.37% | +55,265+39.4% | Added |
| Wells Fargo & Company | 130,886 | $2.29M | 0.00% | −61,990−32.1% | Reduced |
| Citigroup Inc | 129,926 | $2.27M | 0.00% | −29,947−18.7% | Reduced |
| Rhumbline Advisers | 121,341 | $2.12M | 0.00% | −1,581−1.3% | Reduced |
| China Universal Asset Management Co., Ltd. | 121,307 | $2.12M | 0.16% | −8,903−6.8% | Reduced |
| Capital Fund Management S.A. | 113,391 | $1.98M | 0.02% | +39,238+52.9% | Added |
| Cerity Partners LLC | 112,878 | $1.97M | 0.00% | −1,779−1.6% | Reduced |
| Voya Investment Management LLC | 112,437 | $1.97M | 0.00% | −90,181−44.5% | Reduced |
| Profund Advisors LLC | 103,761 | $1.81M | 0.06% | +33,828+48.4% | Added |
| Jefferies Financial Group Inc. | 100,000 | $1.75M | 0.01% | +85,000+566.7% | Added |
| Illinois Municipal Retirement Fund | 99,367 | $1.74M | 0.02% | +30,694+44.7% | Added |
| HSBC Holdings PLC | 98,766 | $1.72M | 0.00% | +98,766 | New |
| NEOS Investment Management LLC | 97,217 | $1.70M | 0.01% | +16,933+21.1% | Added |
| State Board of Administration of Florida Retirement System | 96,009 | $1.68M | 0.00% | 00.0% | Unchanged |
| Tema ETFs LLC | 95,782 | $1.68M | 0.13% | +15,498+19.3% | Added |
| Bank of Montreal | 95,371 | $1.67M | 0.00% | −2,647−2.7% | Reduced |
| State of Wisconsin Investment Board | 92,882 | $1.62M | 0.00% | +1,047+1.1% | Added |
| ADAR1 Capital Management, LLC | 91,869 | $1.61M | 0.12% | −11,100−10.8% | Reduced |
| Colony Group, LLC | 88,448 | $1.55M | 0.00% | +290.0% | Added |
| Dark Forest Capital Management LP | 87,069 | $1.52M | 0.07% | −25,130−22.4% | Reduced |
| Axq Capital, LP | 81,519 | $1.43M | 0.32% | +64,051+366.7% | Added |
| UBS Asset Management Americas Inc | 79,626 | $1.39M | 0.00% | +370.0% | Added |
| Sectoral Asset Management Inc | 79,625 | $1.39M | 1.12% | +5,555+7.5% | Added |
| LMR Partners LLP | 75,200 | $1.32M | 0.01% | +75,200 | New |
| Polianta Ltd | 74,700 | $1.31M | 0.17% | 00.0% | Unchanged |
| Mariner, LLC | 73,497 | $1.29M | 0.00% | −6,075−7.6% | Reduced |
| JPMorgan Chase & Co | 67,422 | $1.18M | 0.00% | −69,204−50.7% | Reduced |
| DnB Asset Management AS | 61,061 | $1.07M | 0.00% | +30,138+97.5% | Added |
| Aquatic Capital Management LLC | 59,945 | $1.05M | 0.03% | +59,945 | New |
| Assenagon Asset Management S.A. | 59,621 | $1.04M | 0.00% | +59,621 | New |
| Wealth Management Partners, LLC | 59,430 | $1.04M | 0.30% | −15,140−20.3% | Reduced |
| Farther Finance Advisors, LLC | 57,282 | $1.00M | 0.01% | +2,046+3.7% | Added |
| Ameriprise Financial Inc | 54,012 | $944.7K | 0.00% | +500+0.9% | Added |
| New York State Common Retirement Fund | 53,777 | $940.6K | 0.00% | −210,513−79.7% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 52,619 | $920.3K | 0.01% | +114+0.2% | Added |
| Balyasny Asset Management LLC | 50,298 | $879.7K | 0.00% | −144,553−74.2% | Reduced |
| Guggenheim Capital LLC | 49,798 | $871.0K | 0.01% | +8,801+21.5% | Added |
| Treasurer of the State of North Carolina | 48,940 | $856.0K | 0.00% | −3,579−6.8% | Reduced |
| Worldquant Millennium Advisors LLC | 41,734 | $729.9K | 0.00% | +41,734 | New |
| Beacon Pointe Advisors, LLC | 39,611 | $692.8K | 0.00% | +3,885+10.9% | Added |
| Mirae Asset Global Investments Co., Ltd. | 37,991 | $664.5K | 0.00% | +7,403+24.2% | Added |
| Levin Capital Strategies, L.P. | 37,676 | $659.0K | 0.06% | +1,000+2.7% | Added |
| Handelsbanken Fonder AB | 37,600 | $658.0K | 0.00% | +3,400+9.9% | Added |
| BNP Paribas Arbitrage, SA | 37,084 | $648.6K | 0.00% | +7,908+27.1% | Added |
| Vident Advisory, LLC | 35,880 | $627.5K | 0.01% | −766−2.1% | Reduced |
| Public Employees Retirement System of Ohio | 35,158 | $614.9K | 0.00% | −1,334−3.7% | Reduced |
| ProShare Advisors LLC | 32,881 | $575.1K | 0.00% | +6,418+24.3% | Added |
| Group One Trading, L.P. | 31,410 | $549.4K | 0.02% | +1,160+3.8% | Added |
| IMC-Chicago, LLC | 29,704 | $519.5K | 0.01% | +29,704 | New |
| Capstone Capital Management Ltd | 28,190 | $493.0K | 0.47% | +28,190 | New |
| First Trust Advisors LP | 28,115 | $491.7K | 0.00% | −143,409−83.6% | Reduced |
| Legal & General Group Plc | 27,359 | $478.5K | 0.00% | +823+3.1% | Added |
| Schonfeld Strategic Advisors LLC | 27,304 | $477.5K | 0.00% | +27,304 | New |
| Eurizon Capital SGR S.p.A. | 25,662 | $448.8K | 0.00% | +25,662 | New |
| Great Valley Advisor Group, Inc. | 25,640 | $448.4K | 0.01% | −33−0.1% | Reduced |
| Entropy Technologies, LP | 25,162 | $440.1K | 0.02% | +25,162 | New |