Ultragenyx Pharmaceutical Inc.
RARE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001515673
In the last 90 days, Ultragenyx Pharmaceutical Inc. insiders filed 0 open-market purchases and 5 sales; 311 institutions reported holding it in 13F filings for Q2 2026, worth $3.55B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Ultragenyx Pharmaceutical Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 288
- −8 vs. Q3 2025
- Shares held
- 93.9M
- −797.2K (−0.8%) vs. Q3 2025
- Total value
- $2.16B
- −$688.2M (−24.1%) vs. Q3 2025
- New holders
- 57
- 111 more added
- Sold out
- 65
- 91 more reduced
7 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RARE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 311 | $3.55B |
| Q1 2026 | 298 | $2.05B |
| Q4 2025 | 288 | $2.16B |
| Q3 2025 | 303 | $2.87B |
| Q2 2025 | 311 | $3.42B |
| Q1 2025 | 301 | $3.25B |
| Q4 2024 | 314 | $3.68B |
| Q3 2024 | 302 | $4.83B |
| Q2 2024 | 275 | $3.63B |
| Q1 2024 | 270 | $3.73B |
| Q4 2023 | 237 | $3.84B |
| Q3 2023 | 221 | $2.52B |
| Q2 2023 | 243 | $3.21B |
| Q1 2023 | 230 | $2.76B |
| Q4 2022 | 228 | $3.15B |
| Q3 2022 | 233 | $2.81B |
| Q2 2022 | 225 | $4.03B |
| Q1 2022 | 240 | $4.87B |
| Q4 2021 | 235 | $5.69B |
| Q3 2021 | 223 | $6.01B |
| Q2 2021 | 242 | $6.24B |
| Q1 2021 | 255 | $7.73B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Ultragenyx Pharmaceutical Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 10,263,815 | $236.1M | 0.00% | +131,087+1.3% | Added |
| BlackRock, Inc. | 6,631,554 | $152.5M | 0.00% | +206,291+3.2% | Added |
| State Street Corp | 4,303,046 | $99.0M | 0.00% | +610,559+16.5% | Added |
| JPMorgan Chase & Co | 3,974,030 | $91.4M | 0.01% | −37,399−0.9% | Reduced |
| Sands Capital Management, LLC | 3,485,724 | $80.2M | 0.24% | −284,129−7.5% | Reduced |
| RTW Investments, LP | 3,000,139 | $69.0M | 0.69% | −258,127−7.9% | Reduced |
| Baker Bros. Advisors LP | 2,772,692 | $63.8M | 0.37% | 00.0% | Unchanged |
| FMR LLC | 2,666,249 | $61.3M | 0.00% | −4,617,047−63.4% | Reduced |
| Wellington Management Group LLP | 2,461,910 | $56.6M | 0.01% | +516,781+26.6% | Added |
| Citadel Advisors LLC | 2,326,125 | $53.5M | 0.04% | +1,995,172+602.9% | Added |
| Suvretta Capital Management, LLC | 2,019,000 | $46.4M | 1.16% | 00.0% | Unchanged |
| Frontier Capital Management Co LLC | 1,965,084 | $45.2M | 0.48% | +895,986+83.8% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,899,661 | $43.7M | 0.05% | +354,382+22.9% | Added |
| Geode Capital Management, LLC | 1,838,208 | $42.3M | 0.00% | +257,701+16.3% | Added |
| Morgan Stanley | 1,826,295 | $42.0M | 0.00% | +916,112+100.7% | Added |
| Jacobs Levy Equity Management, Inc | 1,749,268 | $40.2M | 0.16% | −418,461−19.3% | Reduced |
| Price T Rowe Associates Inc | 1,554,366 | $35.8M | 0.00% | −755,808−32.7% | Reduced |
| Standard Life Aberdeen plc | 1,469,951 | $33.8M | 0.05% | +496,295+51.0% | Added |
| GW&K Investment Management, LLC | 1,375,407 | $31.6M | 0.27% | +225,238+19.6% | Added |
| AQR Capital Management LLC | 1,360,497 | $31.3M | 0.02% | +614,315+82.3% | Added |
| Rock Springs Capital Management LP | 1,267,241 | $29.1M | 1.50% | +20,900+1.7% | Added |
| Norges Bank | 1,261,026 | $29.0M | 0.00% | +1,261,026 | New |
| Bank of America Corp | 1,213,928 | $27.9M | 0.00% | +558,907+85.3% | Added |
| Pictet Asset Management Holding SA | 1,231,331 | $26.6M | 0.03% | −226,856−15.6% | Reduced |
| Jane Street Group, LLC | 1,021,499 | $23.5M | 0.03% | +667,331+188.4% | Added |
| BNP Paribas Arbitrage, SA | 903,050 | $20.8M | 0.01% | +330,031+57.6% | Added |
| Millennium Management LLC | 880,644 | $20.3M | 0.01% | +781,431+787.6% | Added |
| Russell Investments Group, Ltd. | 840,820 | $19.3M | 0.02% | +3690.0% | Added |
| Nuveen, LLC | 801,473 | $18.4M | 0.00% | +119,329+17.5% | Added |
| Candriam Luxembourg S.C.A. | 799,384 | $18.4M | 0.09% | +44,670+5.9% | Added |
| Schonfeld Strategic Advisors LLC | 741,618 | $17.1M | 0.09% | −402,971−35.2% | Reduced |
| UBS Group AG | 668,811 | $15.4M | 0.00% | +121,786+22.3% | Added |
| Voloridge Investment Management, LLC | 643,356 | $14.8M | 0.05% | +160,774+33.3% | Added |
| Deutsche Bank AG | 599,473 | $13.8M | 0.00% | −946,628−61.2% | Reduced |
| Charles Schwab Investment Management Inc | 598,924 | $13.8M | 0.00% | −1,236−0.2% | Reduced |
| Polar Capital Holdings Plc | 556,628 | $12.8M | 0.06% | −27,082−4.6% | Reduced |
| Northern Trust Corp | 526,686 | $12.1M | 0.00% | +27,454+5.5% | Added |
| Balyasny Asset Management LLC | 520,054 | $12.0M | 0.02% | +520,054 | New |
| HRT Financial LP | 501,679 | $11.5M | 0.04% | +501,679 | New |
| Two Sigma Advisers, LP | 481,600 | $11.1M | 0.02% | −36,100−7.0% | Reduced |
| Jefferies Financial Group Inc. | 477,092 | $11.0M | 0.09% | +477,092 | New |
| Palo Alto Investors LP | 461,294 | $10.6M | 1.48% | +91,763+24.8% | Added |
| Two Sigma Investments, LP | 424,049 | $9.75M | 0.01% | +97,869+30.0% | Added |
| Fred Alger Management, LLC | 411,863 | $9.47M | 0.04% | −36,854−8.2% | Reduced |
| Legal & General Group Plc | 411,273 | $9.46M | 0.00% | +8,458+2.1% | Added |
| Goldman Sachs Group Inc | 400,358 | $9.21M | 0.00% | −76,580−16.1% | Reduced |
| Squarepoint Ops LLC | 390,599 | $8.98M | 0.02% | +256,827+192.0% | Added |
| Renaissance Technologies LLC | 366,100 | $8.42M | 0.01% | +344,200+1,571.7% | Added |
| Barclays PLC | 359,148 | $8.26M | 0.00% | −66,203−15.6% | Reduced |
| Privium Fund Management B.V. | 357,502 | $8.22M | 1.51% | +67,698+23.4% | Added |
| Teacher Retirement System of Texas | 348,350 | $8.01M | 0.03% | +327,502+1,570.9% | Added |
| D. E. Shaw & Co., Inc. | 344,763 | $7.93M | 0.01% | +107,123+45.1% | Added |
| Manufacturers Life Insurance Company, The | 331,169 | $7.61M | 0.01% | −13,754−4.0% | Reduced |
| GordonMD Global Investments LP | 329,101 | $7.57M | 5.43% | +329,101 | New |
| Eversept Partners, LP | 317,182 | $7.30M | 0.41% | +317,182 | New |
| Massachusetts Financial Services Co | 310,108 | $7.13M | 0.00% | −191,055−38.1% | Reduced |
| Franklin Resources Inc | 309,062 | $7.11M | 0.00% | −368,122−54.4% | Reduced |
| Sphera Funds Management Ltd. | 300,623 | $6.91M | 1.44% | −51,935−14.7% | Reduced |
| Great Point Partners LLC | 300,000 | $6.90M | 2.24% | +300,000 | New |
| Bank of New York Mellon Corp | 298,706 | $6.87M | 0.00% | −26,139−8.0% | Reduced |
| Motley Fool Wealth Management, LLC | 297,486 | $6.84M | 0.53% | −58,054−16.3% | Reduced |
| Newtyn Management, LLC | 295,915 | $6.81M | 0.72% | +295,915 | New |
| Verition Fund Management LLC | 282,376 | $6.49M | 0.04% | +258,856+1,100.6% | Added |
| Adage Capital Partners GP, L.L.C. | 280,000 | $6.44M | 0.01% | −150,000−34.9% | Reduced |
| Ameriprise Financial Inc | 276,927 | $6.37M | 0.00% | +138,243+99.7% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 263,869 | $6.07M | 0.02% | +184,947+234.3% | Added |
| Ensign Peak Advisors, Inc | 250,571 | $5.76M | 0.01% | +73,150+41.2% | Added |
| Invesco Ltd. | 230,271 | $5.30M | 0.00% | −564,578−71.0% | Reduced |
| 683 Capital Management, LLC | 222,395 | $5.12M | 0.43% | +116,395+109.8% | Added |
| Caption Management, LLC | 219,500 | $5.05M | 0.22% | +54,999+33.4% | Added |
| Algert Global LLC | 219,232 | $5.04M | 0.08% | −102,401−31.8% | Reduced |
| Blue Owl Capital Holdings LP | 212,638 | $4.89M | 1.51% | −209,800−49.7% | Reduced |
| Emerald Advisers, LLC | 212,358 | $4.88M | 0.15% | −206,208−49.3% | Reduced |
| Los Angeles Capital Management LLC | 134,467 | $4.73M | 0.02% | −60,515−31.0% | Reduced |
| UBS Asset Management Americas Inc | 204,107 | $4.69M | 0.00% | −2,935−1.4% | Reduced |
| Moore Capital Management, LP | 200,000 | $4.60M | 0.09% | −70,000−25.9% | Reduced |
| Assenagon Asset Management S.A. | 199,720 | $4.59M | 0.01% | −52,949−21.0% | Reduced |
| Fisher Asset Management, LLC | 198,696 | $4.57M | 0.00% | +30,612+18.2% | Added |
| Nomura Asset Management International Inc. | 182,808 | $4.21M | 0.01% | +182,808 | New |
| PDT Partners, LLC | 176,813 | $4.07M | 0.26% | +20,120+12.8% | Added |
| Schroder Investment Management Group | 175,635 | $4.00M | 0.00% | +25,064+16.6% | Added |
| Woodline Partners LP | 171,805 | $3.95M | 0.02% | −101,446−37.1% | Reduced |
| Swiss National Bank | 171,052 | $3.93M | 0.00% | +6,100+3.7% | Added |
| Trexquant Investment LP | 165,017 | $3.80M | 0.03% | +9,629+6.2% | Added |
| Royal Bank of Canada | 163,227 | $3.75M | 0.00% | −73,062−30.9% | Reduced |
| Catalio Capital Management, LP | 162,550 | $3.74M | 0.66% | −128,712−44.2% | Reduced |
| WCM Investment Management, LLC | 163,272 | $3.72M | 0.01% | −124,837−43.3% | Reduced |
| Rafferty Asset Management, LLC | 157,061 | $3.61M | 0.01% | +577+0.4% | Added |
| SEI Investments Co | 153,726 | $3.54M | 0.00% | −36,736−19.3% | Reduced |
| Susquehanna International Group, LLP | 152,316 | $3.50M | 0.00% | −81,810−34.9% | Reduced |
| Capital Fund Management S.A. | 150,201 | $3.45M | 0.03% | −26,860−15.2% | Reduced |
| Krensavage Asset Management, LLC | 149,634 | $3.44M | 1.22% | +149,634 | New |
| Sr One Capital Management, LP | 137,753 | $3.17M | 0.45% | +137,753 | New |
| ExodusPoint Capital Management, LP | 137,392 | $3.16M | 0.04% | +30,817+28.9% | Added |
| B Group, Inc. | 135,000 | $3.10M | 2.30% | 00.0% | Unchanged |
| DekaBank Deutsche Girozentrale | 57,000 | $2.90M | 0.01% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 122,854 | $2.83M | 0.69% | +122,843+1,116,754.5% | Added |
| Emerald Mutual Fund Advisers Trust | 120,505 | $2.77M | 0.14% | −122,297−50.4% | Reduced |
| XTX Topco Ltd | 119,996 | $2.76M | 0.07% | +105,622+734.8% | Added |
| Comerica Bank | 118,422 | $2.72M | 0.01% | +34,711+41.5% | Added |