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Ultragenyx Pharmaceutical Inc.

RARE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001515673

In the last 90 days, Ultragenyx Pharmaceutical Inc. insiders filed 0 open-market purchases and 5 sales; 311 institutions reported holding it in 13F filings for Q2 2026, worth $3.55B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Ultragenyx Pharmaceutical Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
303
−4 vs. Q2 2025
Shares held
95.5M
+2.33M (+2.5%) vs. Q2 2025
Total value
$2.87B
−$515.2M (−15.2%) vs. Q2 2025
New holders
52
132 more added
Sold out
56
91 more reduced

4 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RARE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 303 institutions
Q1 2021: 255 institutionsQ2 2021: 242 institutionsQ3 2021: 223 institutionsQ4 2021: 235 institutionsQ1 2022: 240 institutionsQ2 2022: 225 institutionsQ3 2022: 233 institutionsQ4 2022: 228 institutionsQ1 2023: 230 institutionsQ2 2023: 243 institutionsQ3 2023: 221 institutionsQ4 2023: 237 institutionsQ1 2024: 270 institutionsQ2 2024: 275 institutionsQ3 2024: 302 institutionsQ4 2024: 314 institutionsQ1 2025: 301 institutionsQ2 2025: 311 institutionsQ3 2025: 303 institutionsQ4 2025: 288 institutionsQ1 2026: 298 institutionsQ2 2026: 311 institutions
Value heldQ3 2025: $2.87B
Q1 2021: $7.73BQ2 2021: $6.24BQ3 2021: $6.01BQ4 2021: $5.69BQ1 2022: $4.87BQ2 2022: $4.03BQ3 2022: $2.81BQ4 2022: $3.15BQ1 2023: $2.76BQ2 2023: $3.21BQ3 2023: $2.52BQ4 2023: $3.84BQ1 2024: $3.73BQ2 2024: $3.63BQ3 2024: $4.83BQ4 2024: $3.68BQ1 2025: $3.25BQ2 2025: $3.42BQ3 2025: $2.87BQ4 2025: $2.16BQ1 2026: $2.05BQ2 2026: $3.55B
Institutions holding RARE and their total value by quarter
QuarterHoldersValue
Q2 2026311$3.55B
Q1 2026298$2.05B
Q4 2025288$2.16B
Q3 2025303$2.87B
Q2 2025311$3.42B
Q1 2025301$3.25B
Q4 2024314$3.68B
Q3 2024302$4.83B
Q2 2024275$3.63B
Q1 2024270$3.73B
Q4 2023237$3.84B
Q3 2023221$2.52B
Q2 2023243$3.21B
Q1 2023230$2.76B
Q4 2022228$3.15B
Q3 2022233$2.81B
Q2 2022225$4.03B
Q1 2022240$4.87B
Q4 2021235$5.69B
Q3 2021223$6.01B
Q2 2021242$6.24B
Q1 2021255$7.73B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Ultragenyx Pharmaceutical Inc.; share changes are against Q2 2025.

Institutions holding RARE in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc10,132,728$304.8M0.00%−80,694−0.8%Reduced
FMR LLC7,283,296$219.1M0.01%+4,678,708+179.6%Added
BlackRock, Inc.6,425,263$193.3M0.00%+169,118+2.7%Added
JPMorgan Chase & Co4,011,429$120.7M0.01%+750,561+23.0%Added
Sands Capital Management, LLC3,769,853$113.4M0.31%−173,632−4.4%Reduced
State Street Corp3,692,487$111.1M0.00%+1,120,247+43.6%Added
RTW Investments, LP3,258,266$98.0M1.21%+1,550,864+90.8%Added
Baker Bros. Advisors LP2,772,692$83.4M0.60%00.0%Unchanged
Price T Rowe Associates Inc2,310,174$69.5M0.01%−576,094−20.0%Reduced
Jacobs Levy Equity Management, Inc2,167,729$65.2M0.26%+1,864,164+614.1%Added
Suvretta Capital Management, LLC2,019,000$60.7M1.84%−259,000−11.4%Reduced
Wellington Management Group LLP1,945,129$58.5M0.01%+73,309+3.9%Added
Geode Capital Management, LLC1,580,507$47.6M0.00%−132,424−7.7%Reduced
Deutsche Bank AG1,546,101$46.5M0.02%−119,751−7.2%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,545,279$46.5M0.12%+93,149+6.4%Added
Pictet Asset Management Holding SA1,458,187$44.0M0.04%−241,757−14.2%Reduced
Rock Springs Capital Management LP1,246,341$37.5M2.19%−144,731−10.4%Reduced
GW&K Investment Management, LLC1,150,169$34.6M0.31%+668,881+139.0%Added
Schonfeld Strategic Advisors LLC1,144,589$34.4M0.24%+577,414+101.8%Added
Frontier Capital Management Co LLC1,069,098$32.2M0.29%+543,634+103.5%Added
Frazier Life Sciences Management, L.P.983,715$29.6M0.89%00.0%Unchanged
Standard Life Aberdeen plc973,656$29.3M0.05%+472,600+94.3%Added
Morgan Stanley910,183$27.4M0.00%+271,304+42.5%Added
Russell Investments Group, Ltd.840,451$25.3M0.03%+720,256+599.2%Added
Invesco Ltd.794,849$23.9M0.00%+70,734+9.8%Added
Candriam Luxembourg S.C.A.754,714$22.7M0.12%+228,447+43.4%Added
Vestal Point Capital, LP750,000$22.6M1.02%+750,000New
AQR Capital Management LLC746,182$22.4M0.01%+493,849+195.7%Added
Eagle Health Investments LP697,000$21.0M5.50%+69,400+11.1%Added
Nuveen, LLC682,144$20.5M0.01%+176,992+35.0%Added
Franklin Resources Inc677,184$20.4M0.01%+202,028+42.5%Added
Bank of America Corp655,021$19.7M0.00%+17,331+2.7%Added
Driehaus Capital Management LLC603,397$18.2M0.13%−3,010−0.5%Reduced
Charles Schwab Investment Management Inc600,160$18.1M0.00%−15,809−2.6%Reduced
Braidwell LP588,700$17.7M0.53%+588,700New
Polar Capital Holdings Plc583,710$17.6M0.08%+32,327+5.9%Added
BNP Paribas Arbitrage, SA573,019$17.2M0.01%+347,193+153.7%Added
UBS Group AG547,025$16.5M0.00%+106,593+24.2%Added
Alyeska Investment Group, L.P.531,996$16.0M0.05%−897,441−62.8%Reduced
Two Sigma Advisers, LP517,700$15.6M0.03%−342,700−39.8%Reduced
Massachusetts Financial Services Co501,163$15.1M0.00%+14,531+3.0%Added
Northern Trust Corp499,232$15.0M0.00%+5,762+1.2%Added
Federated Hermes, Inc.496,060$14.9M0.03%−1,553,441−75.8%Reduced
Voloridge Investment Management, LLC482,582$14.5M0.05%+482,582New
Goldman Sachs Group Inc476,938$14.3M0.00%+50,944+12.0%Added
Fred Alger Management, LLC448,717$13.5M0.05%+18,378+4.3%Added
Adage Capital Partners GP, L.L.C.430,000$12.9M0.02%−1,099,474−71.9%Reduced
Barclays PLC425,351$12.8M0.00%+246,740+138.1%Added
Blue Owl Capital Holdings LP422,438$12.7M3.94%+167,200+65.5%Added
Emerald Advisers, LLC418,566$12.6M0.40%−42,836−9.3%Reduced
AXA Investment Managers S.A.417,198$12.5M0.03%+417,198New
Legal & General Group Plc402,815$12.1M0.00%+89,011+28.4%Added
MPM Oncology Impact Management LP395,700$11.9M1.95%00.0%Unchanged
Palo Alto Investors LP369,531$11.1M2.06%+320,781+658.0%Added
Motley Fool Wealth Management, LLC355,540$10.7M0.73%+80,458+29.2%Added
Jane Street Group, LLC354,168$10.7M0.01%+242,442+217.0%Added
Sphera Funds Management Ltd.352,558$10.6M2.52%+252,473+252.3%Added
Manufacturers Life Insurance Company, The344,923$10.4M0.01%−45,466−11.6%Reduced
Citadel Advisors LLC330,953$9.96M0.01%+293,326+779.6%Added
Two Sigma Investments, LP326,180$9.81M0.02%−250,721−43.5%Reduced
Bank of New York Mellon Corp324,845$9.77M0.00%−149,042−31.5%Reduced
Algert Global LLC321,633$9.67M0.16%+205,286+176.4%Added
Victory Capital Management Inc298,891$8.99M0.01%−116,842−28.1%Reduced
Catalio Capital Management, LP291,262$8.76M1.62%+77,860+36.5%Added
WCM Investment Management, LLC288,109$8.75M0.02%+77,640+36.9%Added
Privium Fund Management B.V.289,804$8.72M1.57%+36,500+14.4%Added
First Light Asset Management, LLC285,699$8.59M0.81%−262,206−47.9%Reduced
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main280,466$8.44M0.01%−30,635−9.8%Reduced
Woodline Partners LP273,251$8.22M0.04%00.0%Unchanged
Moore Capital Management, LP270,000$8.12M0.16%−20,000−6.9%Reduced
Hudson Bay Capital Management LP265,000$7.97M0.05%+6,319+2.4%Added
Assenagon Asset Management S.A.252,669$7.60M0.01%−911,086−78.3%Reduced
Emerald Mutual Fund Advisers Trust242,802$7.30M0.38%−52,515−17.8%Reduced
D. E. Shaw & Co., Inc.237,640$7.15M0.01%−303,161−56.1%Reduced
Royal Bank of Canada236,289$7.11M0.00%+226,246+2,252.8%Added
Susquehanna International Group, LLP234,126$7.04M0.01%+153,903+191.8%Added
Yiheng Capital Management, L.P.225,758$6.79M2.25%+225,758New
UBS Asset Management Americas Inc207,042$6.23M0.00%−93,920−31.2%Reduced
Macquarie Group Ltd200,717$6.04M0.01%−34,380−14.6%Reduced
Los Angeles Capital Management LLC194,982$5.87M0.02%+194,982New
Aquatic Capital Management LLC191,458$5.76M0.11%+84,559+79.1%Added
SEI Investments Co190,462$5.73M0.01%+100,270+111.2%Added
Ensign Peak Advisors, Inc177,421$5.34M0.01%+141,350+391.9%Added
Capital Fund Management S.A.177,061$5.33M0.05%+85,074+92.5%Added
Cubist Systematic Strategies, LLC172,674$5.19M0.07%+87,392+102.5%Added
Fisher Asset Management, LLC168,084$5.06M0.00%−17,672−9.5%Reduced
Swiss National Bank164,952$4.96M0.00%+3,900+2.4%Added
Caption Management, LLC164,501$4.95M0.29%−72,999−30.7%Reduced
PDT Partners, LLC156,693$4.71M0.30%00.0%Unchanged
Rafferty Asset Management, LLC156,484$4.71M0.02%+75,388+93.0%Added
Clearbridge Investments, LLC155,752$4.69M0.00%−1,984,825−92.7%Reduced
Trexquant Investment LP155,388$4.67M0.05%−79,524−33.9%Reduced
Schroder Investment Management Group150,571$4.57M0.00%−185,602−55.2%Reduced
Marshall Wace, LLP146,094$4.39M0.00%+80,223+121.8%Added
Ameriprise Financial Inc138,684$4.17M0.00%+29,447+27.0%Added
B Group, Inc.135,000$4.06M3.88%+25,000+22.7%Added
Squarepoint Ops LLC133,772$4.02M0.01%+112,089+516.9%Added
EFG Asset Management (North America) Corp.127,985$3.85M0.50%−7,865−5.8%Reduced
SG Americas Securities, LLC125,429$3.77M0.01%+125,429New
Gilder Gagnon Howe & Co LLC121,941$3.67M0.04%−1,186−1.0%Reduced