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Ultragenyx Pharmaceutical Inc.

RARE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001515673

In the last 90 days, Ultragenyx Pharmaceutical Inc. insiders filed 0 open-market purchases and 5 sales; 311 institutions reported holding it in 13F filings for Q2 2026, worth $3.55B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Ultragenyx Pharmaceutical Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
288
−8 vs. Q3 2025
Shares held
93.9M
−797.2K (−0.8%) vs. Q3 2025
Total value
$2.16B
−$688.2M (−24.1%) vs. Q3 2025
New holders
57
111 more added
Sold out
65
91 more reduced

7 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RARE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 288 institutions
Q1 2021: 255 institutionsQ2 2021: 242 institutionsQ3 2021: 223 institutionsQ4 2021: 235 institutionsQ1 2022: 240 institutionsQ2 2022: 225 institutionsQ3 2022: 233 institutionsQ4 2022: 228 institutionsQ1 2023: 230 institutionsQ2 2023: 243 institutionsQ3 2023: 221 institutionsQ4 2023: 237 institutionsQ1 2024: 270 institutionsQ2 2024: 275 institutionsQ3 2024: 302 institutionsQ4 2024: 314 institutionsQ1 2025: 301 institutionsQ2 2025: 311 institutionsQ3 2025: 303 institutionsQ4 2025: 288 institutionsQ1 2026: 298 institutionsQ2 2026: 311 institutions
Value heldQ4 2025: $2.16B
Q1 2021: $7.73BQ2 2021: $6.24BQ3 2021: $6.01BQ4 2021: $5.69BQ1 2022: $4.87BQ2 2022: $4.03BQ3 2022: $2.81BQ4 2022: $3.15BQ1 2023: $2.76BQ2 2023: $3.21BQ3 2023: $2.52BQ4 2023: $3.84BQ1 2024: $3.73BQ2 2024: $3.63BQ3 2024: $4.83BQ4 2024: $3.68BQ1 2025: $3.25BQ2 2025: $3.42BQ3 2025: $2.87BQ4 2025: $2.16BQ1 2026: $2.05BQ2 2026: $3.55B
Institutions holding RARE and their total value by quarter
QuarterHoldersValue
Q2 2026311$3.55B
Q1 2026298$2.05B
Q4 2025288$2.16B
Q3 2025303$2.87B
Q2 2025311$3.42B
Q1 2025301$3.25B
Q4 2024314$3.68B
Q3 2024302$4.83B
Q2 2024275$3.63B
Q1 2024270$3.73B
Q4 2023237$3.84B
Q3 2023221$2.52B
Q2 2023243$3.21B
Q1 2023230$2.76B
Q4 2022228$3.15B
Q3 2022233$2.81B
Q2 2022225$4.03B
Q1 2022240$4.87B
Q4 2021235$5.69B
Q3 2021223$6.01B
Q2 2021242$6.24B
Q1 2021255$7.73B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Ultragenyx Pharmaceutical Inc.; share changes are against Q3 2025.

Institutions holding RARE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Jump Financial, LLC115,928$2.67M0.03%+58,460+101.7%Added
Pinnacle Associates Ltd111,560$2.57M0.03%−3,285−2.9%Reduced
Brevan Howard Capital Management LP107,903$2.42M0.05%+40,868+61.0%Added
Rhumbline Advisers101,826$2.34M0.00%−3,905−3.7%Reduced
Twinbeech Capital LP100,152$2.30M0.16%+100,152New
Crestwood Advisors Group LLC100,131$2.30M0.04%−513−0.5%Reduced
Edgestream Partners, L.P.99,873$2.30M0.06%+99,873New
Worldquant Millennium Advisors LLC96,908$2.23M0.01%+96,908New
State Board of Administration of Florida Retirement System96,836$2.23M0.00%+4,070+4.4%Added
Aquatic Capital Management LLC87,464$2.01M0.06%−103,994−54.3%Reduced
California State Teachers Retirement System83,337$1.92M0.00%+2,447+3.0%Added
Sofinnova Investments, Inc.83,300$1.92M0.08%+83,300New
TD Asset Management Inc81,964$1.89M0.00%−15,034−15.5%Reduced
Man Group plc78,371$1.80M0.00%+71,219+995.8%Added
Engineers Gate Manager LP76,702$1.76M0.02%+43,579+131.6%Added
Affinity Asset Advisors, LLC75,000$1.73M0.12%+75,000New
F/M Investments LLC73,484$1.69M0.06%+11,731+19.0%Added
Motley Fool Asset Management LLC72,448$1.67M0.06%−10,152−12.3%Reduced
Marshall Wace, LLP72,168$1.66M0.00%−73,926−50.6%Reduced
Citigroup Inc69,511$1.60M0.00%+43,322+165.4%Added
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main67,339$1.55M0.00%−213,127−76.0%Reduced
Mirae Asset Global ETFs Holdings Ltd.66,175$1.52M0.00%+3,572+5.7%Added
Quadrature Capital Ltd66,001$1.52M0.02%+66,001New
Wells Fargo & Company63,563$1.46M0.00%+38,615+154.8%Added
Hennion & Walsh Asset Management, Inc.62,173$1.43M0.05%−11,621−15.7%Reduced
Parkman Healthcare Partners LLC62,030$1.43M0.14%−6,606−9.6%Reduced
Birchview Capital, LP62,000$1.43M0.83%+40,000+181.8%Added
Fideuram - Intesa Sanpaolo Private Banking S.P.A.61,329$1.41M0.05%+61,329New
Entropy Technologies, LP60,641$1.39M0.08%+40,577+202.2%Added
State of Wisconsin Investment Board58,657$1.35M0.00%−22,281−27.5%Reduced
Nordea Investment Management AB58,838$1.32M0.00%−6,899−10.5%Reduced
Profund Advisors LLC56,624$1.30M0.04%+24,360+75.5%Added
Flax Pond Capital, LLC56,238$1.29M0.96%+56,238New
Ishara Investments LP50,000$1.15M1.34%+50,000New
Quantinno Capital Management LP49,750$1.14M0.00%+11,245+29.2%Added
Guggenheim Capital LLC49,137$1.13M0.01%+2,061+4.4%Added
Scientech Research LLC48,032$1.10M0.69%+16,727+53.4%Added
Wedge Capital Management L L P42,302$972.9K0.02%−877−2.0%Reduced
Police & Firemen's Retirement System of New Jersey39,398$906.2K0.01%+54+0.1%Added
Treasurer of the State of North Carolina38,620$888.0K0.00%−1,763−4.4%Reduced
Alberta Investment Management Corp38,400$883.2K0.01%+38,400New
Janus Henderson Group PLC36,543$840.5K0.00%00.0%Unchanged
Walleye Capital LLC36,484$839.1K0.00%−31,449−46.3%Reduced
Pathstone Holdings, LLC34,339$789.8K0.00%+413+1.2%Added
New York State Common Retirement Fund34,024$782.6K0.00%−1,322−3.7%Reduced
Handelsbanken Fonder AB33,523$771.0K0.00%+6,400+23.6%Added
SG Americas Securities, LLC32,204$741.0K0.00%−93,225−74.3%Reduced
Superstring Capital Management LP31,738$730.0K0.39%+31,738New
Toronto Dominion Bank31,700$729.1K0.00%+31,700New
State of New Jersey Common Pension Fund D29,604$680.9K0.00%−42,451−58.9%Reduced
HSBC Holdings PLC29,679$662.7K0.00%−47,206−61.4%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)28,240$649.5K0.00%+1,875+7.1%Added
Headlands Technologies LLC28,207$648.8K0.05%+2,778+10.9%Added
Public Employees Retirement System of Ohio27,747$638.2K0.00%−312−1.1%Reduced
Alliancebernstein L.P.27,285$627.6K0.00%+577+2.2%Added
S&CO Inc25,255$580.0K0.04%00.0%Unchanged
Arizona State Retirement System23,969$551.3K0.00%−1,207−4.8%Reduced
IMC-Chicago, LLC23,397$538.1K0.01%+23,397New
Group One Trading, L.P.23,208$533.8K0.02%+23,208New
Odyssean, LLC22,230$511.3K0.37%+22,230New
LMR Partners LLP21,674$498.5K0.00%+21,674New
Natixis Advisors, L.P.21,077$485.0K0.00%+1,498+7.7%Added
Oxford Asset Management LLP20,475$470.9K0.17%+20,475New
Virginia Retirement Systems Et Al20,119$462.7K0.00%+6,350+46.1%Added
Envestnet Asset Management Inc20,112$462.6K0.00%−4,921−19.7%Reduced
Knott David M Jr20,006$460.1K0.21%−31,994−61.5%Reduced
Voya Investment Management LLC19,934$458.5K0.00%−679−3.3%Reduced
Victory Capital Management Inc19,907$457.9K0.00%−278,984−93.3%Reduced
Raymond James Financial Inc19,851$456.6K0.00%−4,706−19.2%Reduced
Inceptionr LLC19,714$453.4K0.13%+19,714New
Stifel Financial Corp18,997$436.9K0.00%−6,461−25.4%Reduced
Virtus Investment Advisers, Inc.18,862$433.8K0.12%+7,551+66.8%Added
KLP Kapitalforvaltning AS18,500$425.5K0.00%+800+4.5%Added
First Trust Advisors LP16,642$382.8K0.00%−19,692−54.2%Reduced
Fiduciary Trust Co16,268$374.2K0.00%+3,152+24.0%Added
DAFNA Capital Management LLC16,000$368.0K0.09%+16,000New
China Universal Asset Management Co., Ltd.15,721$361.6K0.03%−1,172−6.9%Reduced
Cerity Partners LLC15,678$360.6K0.00%+15,678New
Xponance, Inc.14,390$331.0K0.00%+896+6.6%Added
Summit Trail Advisors, LLC14,339$329.8K0.01%+5,497+62.2%Added
Universal- Beteiligungs- und Servicegesellschaft mbH14,094$322.9K0.00%−77,300−84.6%Reduced
Mercer Global Advisors Inc13,965$321.2K0.00%+2,036+17.1%Added
Voleon Capital Management LP13,956$321.0K0.01%+13,956New
Tudor Investment Corp Et Al13,416$308.6K0.00%−45,862−77.4%Reduced
Oak Ridge Investments LLC13,394$308.1K0.02%−3,232−19.4%Reduced
Walleye Trading LLC13,167$302.8K0.00%+4,911+59.5%Added
CWM, LLC13,125$302.0K0.00%+9,028+220.4%Added
Erste Asset Management GmbH15,010$296.0K0.00%00.0%Unchanged
B. Metzler seel. Sohn & Co. AG12,862$295.8K0.00%−17,176−57.2%Reduced
Ikarian Capital, LLC12,671$291.4K0.04%+12,671New
SBI Okasan Asset Management Co.Ltd.14,400$284.0K0.02%+14,400New
Blueshift Asset Management, LLC12,343$283.9K0.08%+12,343New
Wealth Enhancement Advisory Services, LLC11,706$263.9K0.00%+1,892+19.3%Added
Captrust Financial Advisors11,378$261.7K0.00%+2,358+26.1%Added
Creative Planning11,266$259.1K0.00%+11,266New
Persistent Asset Partners Ltd11,029$253.7K0.12%+8,947+429.7%Added
Great West Life Assurance Co10,623$245.0K0.00%−16,309−60.6%Reduced
Mariner, LLC10,245$235.7K0.00%+10,245New
Pale Fire Capital SE10,211$234.9K0.03%+10,211New
Marex Group plc9,658$222.1K0.00%+9,658New