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uniQure N.V.

QURE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001590560

In the last 90 days, uniQure N.V. insiders filed 0 open-market purchases and 1 sale; 254 institutions reported holding it in 13F filings for Q2 2026, worth $3.02B in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in uniQure N.V. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
226
+10 vs. Q3 2025
Shares held
62.0M
+6.68M (+12.1%) vs. Q3 2025
Total value
$1.48B
−$1.74B (−54.0%) vs. Q3 2025
New holders
73
73 more added
Sold out
63
61 more reduced

3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting QURE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 226 institutions
Q1 2021: 156 institutionsQ2 2021: 156 institutionsQ3 2021: 176 institutionsQ4 2021: 177 institutionsQ1 2022: 175 institutionsQ2 2022: 169 institutionsQ3 2022: 162 institutionsQ4 2022: 178 institutionsQ1 2023: 175 institutionsQ2 2023: 178 institutionsQ3 2023: 160 institutionsQ4 2023: 144 institutionsQ1 2024: 132 institutionsQ2 2024: 117 institutionsQ3 2024: 131 institutionsQ4 2024: 138 institutionsQ1 2025: 141 institutionsQ2 2025: 143 institutionsQ3 2025: 219 institutionsQ4 2025: 226 institutionsQ1 2026: 214 institutionsQ2 2026: 254 institutions
Value heldQ4 2025: $1.48B
Q1 2021: $1.22BQ2 2021: $1.11BQ3 2021: $1.19BQ4 2021: $783.5MQ1 2022: $685.7MQ2 2022: $756.3MQ3 2022: $788.8MQ4 2022: $912.1MQ1 2023: $838.6MQ2 2023: $412.8MQ3 2023: $240.1MQ4 2023: $255.8MQ1 2024: $168.5MQ2 2024: $142.2MQ3 2024: $193.4MQ4 2024: $735.8MQ1 2025: $533.2MQ2 2025: $738.3MQ3 2025: $3.23BQ4 2025: $1.48BQ1 2026: $972.4MQ2 2026: $3.02B
Institutions holding QURE and their total value by quarter
QuarterHoldersValue
Q2 2026254$3.02B
Q1 2026214$972.4M
Q4 2025226$1.48B
Q3 2025219$3.23B
Q2 2025143$738.3M
Q1 2025141$533.2M
Q4 2024138$735.8M
Q3 2024131$193.4M
Q2 2024117$142.2M
Q1 2024132$168.5M
Q4 2023144$255.8M
Q3 2023160$240.1M
Q2 2023178$412.8M
Q1 2023175$838.6M
Q4 2022178$912.1M
Q3 2022162$788.8M
Q2 2022169$756.3M
Q1 2022175$685.7M
Q4 2021177$783.5M
Q3 2021176$1.19B
Q2 2021156$1.11B
Q1 2021156$1.22B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding uniQure N.V.; share changes are against Q3 2025.

Institutions holding QURE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Tyro Capital Management LLC663,929$15.9M4.94%+663,929New
Logos Global Management LP675,000$16.2M1.08%+375,000+125.0%Added
Nantahala Capital Management, LLC699,298$16.7M1.00%−308,194−30.6%Reduced
Morgan Stanley716,927$17.2M0.00%+395,426+123.0%Added
OrbiMed Advisors LLC737,400$17.6M0.36%+278,900+60.8%Added
Franklin Resources Inc746,602$17.9M0.00%−1,241,979−62.5%Reduced
Fiera Capital Corp768,510$18.4M0.06%+768,510New
Geode Capital Management, LLC776,071$18.6M0.00%+54,419+7.5%Added
Millennium Management LLC803,605$19.2M0.01%+612,005+319.4%Added
Integral Health Asset Management, LLC900,000$21.5M1.09%+300,000+50.0%Added
Artia Global Partners LP1,023,539$24.5M3.94%+364,700+55.4%Added
Vanguard Group Inc1,051,379$25.2M0.00%−73,729−6.6%Reduced
Two Sigma Advisers, LP1,110,400$26.6M0.05%+700,900+171.2%Added
Goldman Sachs Group Inc1,167,608$27.9M0.00%+505,400+76.3%Added
Suvretta Capital Management, LLC1,216,734$29.1M0.73%+1,216,734New
Susquehanna International Group, LLP1,218,350$29.2M0.04%+992,810+440.2%Added
Jennison Associates LLC1,371,190$32.8M0.02%+371,706+37.2%Added
MPM Oncology Impact Management LP1,381,628$33.1M3.78%+1,381,628New
Two Sigma Investments, LP1,451,284$34.7M0.05%+553,746+61.7%Added
BlackRock, Inc.1,974,988$47.3M0.00%+528,889+36.6%Added
JPMorgan Chase & Co2,934,626$70.2M0.00%+1,785,275+155.3%Added
State Street Corp3,231,043$77.3M0.00%+1,787,033+123.8%Added
Standard Life Aberdeen plc3,678,640$88.0M0.14%+738,897+25.1%Added
RTW Investments, LP3,711,462$88.8M0.89%−713,506−16.1%Reduced
Avoro Capital Advisors LLC6,150,000$147.2M1.45%+1,705,556+38.4%Added
FMR LLC6,240,936$149.3M0.01%+181,362+3.0%Added
EcoR1 Capital, LLC0$00.00%−3,988,971−100.0%Sold out
Deep Track Capital, LP0$00.00%−483,092−100.0%Sold out
Darwin Global Management, Ltd.0$00.00%−400,000−100.0%Sold out
Siren, L.L.C.0$00.00%−275,200−100.0%Sold out
Macquarie Group Ltd0$00.00%−258,211−100.0%Sold out
Vestal Point Capital, LP0$00.00%−225,000−100.0%Sold out
Ra Capital Management, L.P.0$00.00%−200,000−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−200,000−100.0%Sold out
Lord, Abbett & Co. LLC0$00.00%−176,025−100.0%Sold out
Boone Capital Management LLC0$00.00%−147,317−100.0%Sold out
Group One Trading, L.P.0$00.00%−140,227−100.0%Sold out
Woodline Partners LP0$00.00%−130,615−100.0%Sold out
Rosalind Advisors, Inc.0$00.00%−125,000−100.0%Sold out
Atika Capital Management LLC0$00.00%−90,000−100.0%Sold out
Sanders Morris Harris LLC0$00.00%−87,054−100.0%Sold out
Patient Square Capital LP0$00.00%−75,000−100.0%Sold out
Apis Capital Advisors, LLC0$00.00%−63,800−100.0%Sold out
Verition Fund Management LLC0$00.00%−57,968−100.0%Sold out
Longaeva Partners L.P.0$00.00%−55,000−100.0%Sold out
Owl Creek Asset Management, L.P.0$00.00%−49,389−100.0%Sold out
Monashee Investment Management LLC0$00.00%−40,000−100.0%Sold out
Gilder Gagnon Howe & Co LLC0$00.00%−34,084−100.0%Sold out
Superstring Capital Management LP0$00.00%−33,175−100.0%Sold out
Velan Capital Investment Management LP0$00.00%−32,000−100.0%Sold out
Invesco Ltd.0$00.00%−30,264−100.0%Sold out
Virtu Financial LLC0$00.00%−28,201−100.0%Sold out
Sphera Funds Management Ltd.0$00.00%−24,900−100.0%Sold out
Aristides Capital LLC0$00.00%−22,500−100.0%Sold out
Exome Asset Management LLC0$00.00%−22,090−100.0%Sold out
Palumbo Wealth Management LLC0$00.00%−21,778−100.0%Sold out
Perceptive Advisors LLC0$00.00%−20,000−100.0%Sold out
Resolute Capital Asset Partners LLC0$00.00%−20,000−100.0%Sold out
Polymer Capital Management (US) LLC0$00.00%−17,835−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−15,125−100.0%Sold out
Raymond James Financial Inc0$00.00%−14,698−100.0%Sold out
CI Private Wealth, LLC0$00.00%−10,562−100.0%Sold out
Teacher Retirement System of Texas0$00.00%−8,646−100.0%Sold out
Sig Brokerage, LP0$00.00%−7,831−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−7,771−100.0%Sold out
Total Clarity Wealth Management, Inc.0$00.00%−7,608−100.0%Sold out
NEOS Investment Management LLC0$00.00%−6,250−100.0%Sold out
Tema ETFs LLC0$00.00%−6,250−100.0%Sold out
SCS Capital Management LLC0$00.00%−6,164−100.0%Sold out
Pictet Asset Management Holding SA0$00.00%−5,900−100.0%Sold out
Ballentine Partners, LLC0$00.00%−5,153−100.0%Sold out
Financial Engines Advisors L.L.C.0$00.00%−4,767−100.0%Sold out
Creative Planning0$00.00%−4,735−100.0%Sold out
Sigma Planning Corp0$00.00%−4,500−100.0%Sold out
Requisite Capital Management, LLC0$00.00%−4,092−100.0%Sold out
Coppell Advisory Solutions LLC0$00.00%−4,000−100.0%Sold out
Gordian Capital Singapore Pte Ltd0$00.00%−3,900−100.0%Sold out
Commonwealth Equity Services, LLC0$00.00%−3,880−100.0%Sold out
Westfield Capital Management Co LP0$00.00%−3,828−100.0%Sold out
T. Rowe Price Investment Management, Inc.0$00.00%−977−100.0%Sold out
Private Trust Co NA0$00.00%−485−100.0%Sold out
Salem Investment Counselors Inc0$00.00%−300−100.0%Sold out
Washington Trust Advisors, Inc.0$00.00%−121−100.0%Sold out
Caitong International Asset Management Co., Ltd0$00.00%−116−100.0%Sold out
LRI Investments, LLC0$00.00%−87−100.0%Sold out
Grove Bank & Trust0$00.00%−70−100.0%Sold out
Ancora Advisors, LLC0$00.00%−51−100.0%Sold out
Bellevue Asset Management, LLC0$00.00%−46−100.0%Sold out
Principal Securities, Inc.0$00.00%−19−100.0%Sold out
Cubist Systematic Strategies, LLC––––Not filed
Wolverine Trading, LLC––––Not filed
Point72 Europe (London) LLP––––Not filed