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uniQure N.V.

QURE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001590560

In the last 90 days, uniQure N.V. insiders filed 0 open-market purchases and 3 sales; 254 institutions reported holding it in 13F filings for Q2 2026, worth $3.02B in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in uniQure N.V. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
226
+10 vs. Q3 2025
Shares held
62.0M
+6.68M (+12.1%) vs. Q3 2025
Total value
$1.48B
−$1.74B (−54.0%) vs. Q3 2025
New holders
73
73 more added
Sold out
63
61 more reduced

3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting QURE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 226 institutions
Q1 2021: 156 institutionsQ2 2021: 156 institutionsQ3 2021: 176 institutionsQ4 2021: 177 institutionsQ1 2022: 175 institutionsQ2 2022: 169 institutionsQ3 2022: 162 institutionsQ4 2022: 178 institutionsQ1 2023: 175 institutionsQ2 2023: 178 institutionsQ3 2023: 160 institutionsQ4 2023: 144 institutionsQ1 2024: 132 institutionsQ2 2024: 117 institutionsQ3 2024: 131 institutionsQ4 2024: 138 institutionsQ1 2025: 141 institutionsQ2 2025: 143 institutionsQ3 2025: 219 institutionsQ4 2025: 226 institutionsQ1 2026: 214 institutionsQ2 2026: 254 institutions
Value heldQ4 2025: $1.48B
Q1 2021: $1.22BQ2 2021: $1.11BQ3 2021: $1.19BQ4 2021: $783.5MQ1 2022: $685.7MQ2 2022: $756.3MQ3 2022: $788.8MQ4 2022: $912.1MQ1 2023: $838.6MQ2 2023: $412.8MQ3 2023: $240.1MQ4 2023: $255.8MQ1 2024: $168.5MQ2 2024: $142.2MQ3 2024: $193.4MQ4 2024: $735.8MQ1 2025: $533.2MQ2 2025: $738.3MQ3 2025: $3.23BQ4 2025: $1.48BQ1 2026: $972.4MQ2 2026: $3.02B
Institutions holding QURE and their total value by quarter
QuarterHoldersValue
Q2 2026254$3.02B
Q1 2026214$972.4M
Q4 2025226$1.48B
Q3 2025219$3.23B
Q2 2025143$738.3M
Q1 2025141$533.2M
Q4 2024138$735.8M
Q3 2024131$193.4M
Q2 2024117$142.2M
Q1 2024132$168.5M
Q4 2023144$255.8M
Q3 2023160$240.1M
Q2 2023178$412.8M
Q1 2023175$838.6M
Q4 2022178$912.1M
Q3 2022162$788.8M
Q2 2022169$756.3M
Q1 2022175$685.7M
Q4 2021177$783.5M
Q3 2021176$1.19B
Q2 2021156$1.11B
Q1 2021156$1.22B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding uniQure N.V.; share changes are against Q3 2025.

Institutions holding QURE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC6,240,936$149.3M0.01%+181,362+3.0%Added
Avoro Capital Advisors LLC6,150,000$147.2M1.45%+1,705,556+38.4%Added
RTW Investments, LP3,711,462$88.8M0.89%−713,506−16.1%Reduced
Standard Life Aberdeen plc3,678,640$88.0M0.14%+738,897+25.1%Added
State Street Corp3,231,043$77.3M0.00%+1,787,033+123.8%Added
JPMorgan Chase & Co2,934,626$70.2M0.00%+1,785,275+155.3%Added
BlackRock, Inc.1,974,988$47.3M0.00%+528,889+36.6%Added
Two Sigma Investments, LP1,451,284$34.7M0.05%+553,746+61.7%Added
MPM Oncology Impact Management LP1,381,628$33.1M3.78%+1,381,628New
Jennison Associates LLC1,371,190$32.8M0.02%+371,706+37.2%Added
Susquehanna International Group, LLP1,218,350$29.2M0.04%+992,810+440.2%Added
Suvretta Capital Management, LLC1,216,734$29.1M0.73%+1,216,734New
Goldman Sachs Group Inc1,167,608$27.9M0.00%+505,400+76.3%Added
Two Sigma Advisers, LP1,110,400$26.6M0.05%+700,900+171.2%Added
Vanguard Group Inc1,051,379$25.2M0.00%−73,729−6.6%Reduced
Artia Global Partners LP1,023,539$24.5M3.94%+364,700+55.4%Added
Integral Health Asset Management, LLC900,000$21.5M1.09%+300,000+50.0%Added
Millennium Management LLC803,605$19.2M0.01%+612,005+319.4%Added
Geode Capital Management, LLC776,071$18.6M0.00%+54,419+7.5%Added
Fiera Capital Corp768,510$18.4M0.06%+768,510New
Franklin Resources Inc746,602$17.9M0.00%−1,241,979−62.5%Reduced
OrbiMed Advisors LLC737,400$17.6M0.36%+278,900+60.8%Added
Morgan Stanley716,927$17.2M0.00%+395,426+123.0%Added
Nantahala Capital Management, LLC699,298$16.7M1.00%−308,194−30.6%Reduced
Logos Global Management LP675,000$16.2M1.08%+375,000+125.0%Added
Tyro Capital Management LLC663,929$15.9M4.94%+663,929New
Maverick Capital LtdSuperinvestorMaverick Capital661,820$15.8M0.17%+661,820New
Assenagon Asset Management S.A.606,923$14.5M0.02%+606,923New
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.521,677$12.5M1.11%00.0%Unchanged
Eventide Asset Management, LLC498,212$11.9M0.19%+498,212New
UBS Group AG491,454$11.8M0.00%+286,465+139.7%Added
Citadel Advisors LLC469,300$11.2M0.01%+39,590+9.2%Added
Whitefort Capital Management, LP459,000$11.0M3.32%+459,000New
Privium Fund Management B.V.416,270$9.96M1.83%+30,270+7.8%Added
683 Capital Management, LLC384,950$9.21M0.77%−685,050−64.0%Reduced
Charles Schwab Investment Management Inc362,878$8.68M0.00%+5,193+1.5%Added
Readystate Asset Management LP361,560$8.65M0.38%+361,560New
Fred Alger Management, LLC344,878$8.25M0.03%−945,513−73.3%Reduced
Bank of America Corp329,525$7.89M0.00%+34,394+11.7%Added
First Turn Management, LLC321,655$7.70M0.88%+321,655New
HRT Financial LP310,050$7.42M0.02%+310,050New
Jump Financial, LLC306,131$7.33M0.09%+302,305+7,901.3%Added
Boxer Capital Management, LLC290,000$6.94M1.52%−510,000−63.7%Reduced
Catalio Capital Management, LP288,345$6.90M1.22%+5,405+1.9%Added
Nomura Asset Management International Inc.258,211$6.18M0.01%+258,211New
Parkman Healthcare Partners LLC257,382$6.16M0.59%−87,974−25.5%Reduced
ADAR1 Capital Management, LLC235,155$5.63M0.42%+101,839+76.4%Added
Freshford Capital Management, LLC229,613$5.49M2.20%+229,613New
BNP Paribas Arbitrage, SA221,343$5.30M0.00%−164,266−42.6%Reduced
Voss Capital, LLC210,000$5.03M0.27%+85,000+68.0%Added
Barclays PLC209,790$5.02M0.00%+94,228+81.5%Added
Price T Rowe Associates Inc208,646$4.99M0.00%−704,534−77.2%Reduced
Eagle Health Investments LP205,247$4.91M1.08%+205,247New
Citigroup Inc184,765$4.42M0.00%+173,190+1,496.2%Added
Caption Management, LLC177,277$4.24M0.19%−281,023−61.3%Reduced
Sofinnova Investments, Inc.176,513$4.22M0.18%+39,651+29.0%Added
Squarepoint Ops LLC176,000$4.21M0.01%−5,902−3.2%Reduced
Northern Trust Corp168,820$4.04M0.00%+16,383+10.7%Added
Rafferty Asset Management, LLC164,937$3.95M0.01%+82,081+99.1%Added
Alyeska Investment Group, L.P.151,058$3.61M0.01%+111,058+277.6%Added
New York State Common Retirement Fund147,549$3.53M0.00%+147,549New
Flax Pond Capital, LLC146,498$3.51M2.61%+146,498New
Balyasny Asset Management LLC135,644$3.25M0.01%−197,591−59.3%Reduced
D. E. Shaw & Co., Inc.131,956$3.16M0.00%+99,419+305.6%Added
Silverarc Capital Management, LLC126,047$3.02M0.44%−328,953−72.3%Reduced
Hudson Bay Capital Management LP125,500$3.00M0.02%+121,182+2,806.4%Added
Schonfeld Strategic Advisors LLC122,529$2.93M0.01%−65,668−34.9%Reduced
Nan Fung Trinity (HK) Ltd115,494$2.76M0.22%+115,494New
Simplex Trading, LLC110,675$2.65M0.07%+42,680+62.8%Added
Envestnet Asset Management Inc99,593$2.38M0.00%+88,044+762.4%Added
Ikarian Capital, LLC91,060$2.18M0.28%+32,450+55.4%Added
Jefferies Financial Group Inc.90,542$2.17M0.02%00.0%Unchanged
Deeter Investments LLP89,085$2.13M0.46%+89,085New
Marex Group plc85,993$2.06M0.02%−866−1.0%Reduced
Royal Bank of Canada85,640$2.05M0.00%−125,773−59.5%Reduced
Clearline Capital LP83,681$2.00M0.15%+83,681New
Capital Fund Management S.A.82,978$1.99M0.02%+82,978New
UBS Asset Management Americas Inc80,249$1.92M0.00%+80,249New
Rhenman & Partners Asset Management AB79,375$1.90M0.18%+79,375New
Swiss National Bank79,000$1.89M0.00%+2,700+3.5%Added
Walleye Capital LLC78,996$1.89M0.01%−23,913−23.2%Reduced
Atom Investors LP78,209$1.87M0.15%+30,918+65.4%Added
Moore Capital Management, LP75,000$1.79M0.04%+75,000New
Tudor Investment Corp Et Al74,036$1.77M0.01%+45,319+157.8%Added
ExodusPoint Capital Management, LP73,775$1.77M0.02%+73,775New
Algert Global LLC72,150$1.73M0.03%+49,340+216.3%Added
Ameriprise Financial Inc70,796$1.69M0.00%−88,147−55.5%Reduced
Wells Fargo & Company70,236$1.68M0.00%+59,393+547.8%Added
Hennion & Walsh Asset Management, Inc.67,739$1.62M0.06%+16,126+31.2%Added
SG Americas Securities, LLC64,326$1.54M0.00%+53,747+508.1%Added
Eversept Partners, LP62,820$1.50M0.08%−814,553−92.8%Reduced
Profund Advisors LLC59,463$1.42M0.04%+42,379+248.1%Added
Schroder Investment Management Group55,015$1.31M0.00%+55,015New
Affinity Asset Advisors, LLC50,000$1.20M0.09%−250,000−83.3%Reduced
Senvest Management, LLC50,000$1.20M0.04%+50,000New
Winton Group Ltd48,185$1.15M0.04%+7,209+17.6%Added
Stifel Financial Corp45,987$1.10M0.00%−12,289−21.1%Reduced
Y-Intercept (Hong Kong) Ltd45,778$1.10M0.02%+23,074+101.6%Added
Diadema Partners LP45,000$1.08M0.64%+45,000New
Mirae Asset Global ETFs Holdings Ltd.44,250$1.06M0.00%+6,961+18.7%Added