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uniQure N.V.

QURE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001590560

No open-market purchases or sales by uniQure N.V. insiders were filed in the last 90 days; 254 institutions reported holding it in 13F filings for Q2 2026, worth $3.02B in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in uniQure N.V. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
226
+10 vs. Q3 2025
Shares held
62.0M
+6.68M (+12.1%) vs. Q3 2025
Total value
$1.48B
−$1.74B (−54.0%) vs. Q3 2025
New holders
73
73 more added
Sold out
63
61 more reduced

3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting QURE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 226 institutions
Q1 2021: 156 institutionsQ2 2021: 156 institutionsQ3 2021: 176 institutionsQ4 2021: 177 institutionsQ1 2022: 175 institutionsQ2 2022: 169 institutionsQ3 2022: 162 institutionsQ4 2022: 178 institutionsQ1 2023: 175 institutionsQ2 2023: 178 institutionsQ3 2023: 160 institutionsQ4 2023: 144 institutionsQ1 2024: 132 institutionsQ2 2024: 117 institutionsQ3 2024: 131 institutionsQ4 2024: 138 institutionsQ1 2025: 141 institutionsQ2 2025: 143 institutionsQ3 2025: 219 institutionsQ4 2025: 226 institutionsQ1 2026: 214 institutionsQ2 2026: 254 institutions
Value heldQ4 2025: $1.48B
Q1 2021: $1.22BQ2 2021: $1.11BQ3 2021: $1.19BQ4 2021: $783.5MQ1 2022: $685.7MQ2 2022: $756.3MQ3 2022: $788.8MQ4 2022: $912.1MQ1 2023: $838.6MQ2 2023: $412.8MQ3 2023: $240.1MQ4 2023: $255.8MQ1 2024: $168.5MQ2 2024: $142.2MQ3 2024: $193.4MQ4 2024: $735.8MQ1 2025: $533.2MQ2 2025: $738.3MQ3 2025: $3.23BQ4 2025: $1.48BQ1 2026: $972.4MQ2 2026: $3.02B
Institutions holding QURE and their total value by quarter
QuarterHoldersValue
Q2 2026254$3.02B
Q1 2026214$972.4M
Q4 2025226$1.48B
Q3 2025219$3.23B
Q2 2025143$738.3M
Q1 2025141$533.2M
Q4 2024138$735.8M
Q3 2024131$193.4M
Q2 2024117$142.2M
Q1 2024132$168.5M
Q4 2023144$255.8M
Q3 2023160$240.1M
Q2 2023178$412.8M
Q1 2023175$838.6M
Q4 2022178$912.1M
Q3 2022162$788.8M
Q2 2022169$756.3M
Q1 2022175$685.7M
Q4 2021177$783.5M
Q3 2021176$1.19B
Q2 2021156$1.11B
Q1 2021156$1.22B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding uniQure N.V.; share changes are against Q3 2025.

Institutions holding QURE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
StemPoint Capital LP43,485$1.04M0.18%−478,670−91.7%Reduced
Engineers Gate Manager LP43,356$1.04M0.01%+43,356New
Bank of New York Mellon Corp43,309$1.04M0.00%+21,098+95.0%Added
Tejara Capital Ltd42,000$1.01M0.42%+42,000New
Shay Capital LLC41,073$982.9K0.16%+6,076+17.4%Added
Massar Capital Management, LP40,529$969.9K0.19%+20,529+102.6%Added
Headlands Technologies LLC39,616$948.0K0.08%−17,792−31.0%Reduced
PFM Health Sciences, LP39,499$945.2K0.10%−6,854−14.8%Reduced
Ci Investments Inc.37,841$905.5K0.00%−9,595−20.2%Reduced
California State Teachers Retirement System35,947$860.2K0.00%+4,636+14.8%Added
MML Investors Services, LLC33,937$812.1K0.00%+33,937New
Diamond Hill Capital Management Inc33,333$797.7K0.00%00.0%Unchanged
Legal & General Group Plc31,964$764.9K0.00%−3,657−10.3%Reduced
BIT Capital GmbH31,614$756.5K0.03%+31,614New
Birchview Capital, LP30,789$736.8K0.43%−47,939−60.9%Reduced
Sectoral Asset Management Inc30,585$731.9K0.59%−155−0.5%Reduced
Boothbay Fund Management, LLC30,448$728.6K0.02%−8,955−22.7%Reduced
Havemeyer Place LP29,655$709.6K0.14%+29,655New
Pekin Hardy Strauss, Inc.29,300$701.1K0.06%+29,300New
Voya Investment Management LLC28,850$690.4K0.00%−73,274−71.8%Reduced
Susquehanna Portfolio Strategies, LLC28,708$687.0K0.01%−840−2.8%Reduced
SummitTX Capital, L.P.27,708$663.1K0.02%+22,010+386.3%Added
DnB Asset Management AS27,342$654.3K0.00%+15,540+131.7%Added
Monimus Capital Management, LP25,878$619.3K0.41%+25,878New
Monaco Asset Management SAM25,000$598.3K0.18%−14,913−37.4%Reduced
Point72 Asset Management, L.P.24,439$584.8K0.00%−229,643−90.4%Reduced
TD Asset Management Inc23,734$568.0K0.00%−71,410−75.1%Reduced
Russell Investments Group, Ltd.23,707$567.3K0.00%−126,144−84.2%Reduced
LPL Financial LLC21,969$525.7K0.00%−24,145−52.4%Reduced
Marshall Wace, LLP21,159$506.3K0.00%−87,051−80.4%Reduced
J. Goldman & Co LP20,250$484.6K0.02%+20,250New
Voleon Capital Management LP20,243$484.4K0.01%+20,243New
Burkehill Global Management, LP20,000$478.6K0.03%00.0%Unchanged
State of Wisconsin Investment Board19,390$464.0K0.00%+15,822+443.4%Added
Zurcher Kantonalbank (Zurich Cantonalbank)19,007$454.8K0.00%−890−4.5%Reduced
Assetmark, Inc18,613$445.4K0.00%+18,613New
Clear Harbor Asset Management, LLC16,900$404.4K0.03%+9,900+141.4%Added
Janus Henderson Group PLC16,900$404.3K0.00%−3,000−15.1%Reduced
Manufacturers Life Insurance Company, The16,462$391.5K0.00%−32,300−66.2%Reduced
Qsemble Capital Management, LP15,931$381.2K0.03%+15,931New
Prelude Capital Management, LLC15,739$376.6K0.03%+3,579+29.4%Added
Nomura Holdings Inc15,584$372.9K0.00%+15,584New
Handelsbanken Fonder AB14,900$357.0K0.00%+14,900New
Lion Point Capital, LP14,700$351.8K1.82%+14,700New
Farallon Capital Management, L.L.C.14,000$335.0K0.00%−551,000−97.5%Reduced
SEI Investments Co13,938$333.4K0.00%−53,335−79.3%Reduced
Virtus Investment Advisers, Inc.13,636$326.3K0.09%+6,520+91.6%Added
Lido Advisors, LLC5,544$323.6K0.00%00.0%Unchanged
FORA Capital, LLC13,313$318.6K0.04%+13,313New
Freestone Grove Partners LP12,984$310.7K0.00%+12,984New
Lighthouse Investment Partners, LLC12,500$299.1K0.01%+12,500New
JustInvest LLC12,356$295.7K0.00%−83−0.7%Reduced
Vontobel Holding Ltd.11,933$285.6K0.00%+11,933New
Diametric Capital, LP11,822$282.9K0.08%+6,439+119.6%Added
Arizona State Retirement System11,141$266.6K0.00%+627+6.0%Added
Persistent Asset Partners Ltd11,014$263.6K0.13%+11,014New
Brinker Capital Investments, LLC10,768$257.7K0.00%+10,768New
Sassicaia Capital Advisers LLC10,400$248.9K0.55%−5,600−35.0%Reduced
Scientech Research LLC10,203$244.2K0.15%−19,092−65.2%Reduced
China Universal Asset Management Co., Ltd.10,150$242.9K0.02%+533+5.5%Added
Quinn Opportunity Partners LLC10,000$239.3K0.01%−97,600−90.7%Reduced
Ashford Capital Management Inc10,000$239.3K0.03%+10,000New
Pavaki Capital Management LLC9,810$234.8K0.16%+9,810New
Graham Capital Management, L.P.9,013$215.7K0.01%+9,013New
Seven Fleet Capital Management LP8,742$209.2K0.14%+8,742New
Militia Capital Partners, LP8,500$203.4K0.08%−26,500−75.7%Reduced
Rangeley Capital, LLC8,500$203.4K0.18%+8,500New
Mraz, Amerine & Associates, Inc.8,495$203.3K0.03%−824−8.8%Reduced
KLP Kapitalforvaltning AS8,400$201.0K0.00%00.0%Unchanged
Cetera Investment Advisers8,366$200.2K0.00%+8,366New
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.8,098$189.4K0.00%−7,352−47.6%Reduced
Walleye Trading LLC7,657$183.2K0.00%−39,664−83.8%Reduced
US Bancorp6,171$147.7K0.00%+5,466+775.3%Added
Quantbot Technologies LP5,444$130.3K0.00%+5,444New
Activest Wealth Management5,000$119.7K0.02%00.0%Unchanged
Bellevue Group AG4,763$114.0K0.00%00.0%Unchanged
Deutsche Bank AG4,621$110.6K0.00%+2,291+98.3%Added
Knott David M Jr4,000$95.7K0.04%+2,000+100.0%Added
Ensign Peak Advisors, Inc3,650$87.3K0.00%+650+21.7%Added
Mirae Asset Global Investments Co., Ltd.3,027$72.4K0.00%+906+42.7%Added
FNY Investment Advisers, LLC2,080$49.0K0.01%+426+25.8%Added
IFP Advisors, Inc1,989$47.6K0.00%+1,989New
Smartleaf Asset Management LLC2,000$47.6K0.00%+2,000New
GF Fund Management Co. Ltd.1,223$29.3K0.00%+43+3.6%Added
Torren Management, LLC1,169$28.0K0.01%+1,169New
CIBC Private Wealth Group, LLC850$20.3K0.00%00.0%Unchanged
Parallel Advisors, LLC848$20.3K0.00%+848New
Comerica Bank637$15.2K0.00%+230+56.5%Added
Advisor Group Holdings, Inc.587$14.0K0.00%+476+428.8%Added
Jones Financial Companies LLLP418$10.0K0.00%−191−31.4%Reduced
Cygnus Capital Advisors, LLC288$7.00K0.01%+288New
SBI Securities Co., Ltd.280$6.70K0.00%−858−75.4%Reduced
CWM, LLC247$6.00K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC250$5.98K0.00%00.0%Unchanged
Signaturefd, LLC249$5.96K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.247$5.91K0.00%−753−75.3%Reduced
Umb Bank N A200$4.79K0.00%00.0%Unchanged
Entrust Financial LLC190$4.55K0.00%+190New
Quadrant Capital Group LLC187$4.47K0.00%00.0%Unchanged
Allworth Financial LP174$4.16K0.00%00.0%Unchanged