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uniQure N.V.

QURE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001590560

In the last 90 days, uniQure N.V. insiders filed 0 open-market purchases and 1 sale; 254 institutions reported holding it in 13F filings for Q2 2026, worth $3.02B in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in uniQure N.V. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
226
+10 vs. Q3 2025
Shares held
62.0M
+6.68M (+12.1%) vs. Q3 2025
Total value
$1.48B
−$1.74B (−54.0%) vs. Q3 2025
New holders
73
73 more added
Sold out
63
61 more reduced

3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting QURE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 226 institutions
Q1 2021: 156 institutionsQ2 2021: 156 institutionsQ3 2021: 176 institutionsQ4 2021: 177 institutionsQ1 2022: 175 institutionsQ2 2022: 169 institutionsQ3 2022: 162 institutionsQ4 2022: 178 institutionsQ1 2023: 175 institutionsQ2 2023: 178 institutionsQ3 2023: 160 institutionsQ4 2023: 144 institutionsQ1 2024: 132 institutionsQ2 2024: 117 institutionsQ3 2024: 131 institutionsQ4 2024: 138 institutionsQ1 2025: 141 institutionsQ2 2025: 143 institutionsQ3 2025: 219 institutionsQ4 2025: 226 institutionsQ1 2026: 214 institutionsQ2 2026: 254 institutions
Value heldQ4 2025: $1.48B
Q1 2021: $1.22BQ2 2021: $1.11BQ3 2021: $1.19BQ4 2021: $783.5MQ1 2022: $685.7MQ2 2022: $756.3MQ3 2022: $788.8MQ4 2022: $912.1MQ1 2023: $838.6MQ2 2023: $412.8MQ3 2023: $240.1MQ4 2023: $255.8MQ1 2024: $168.5MQ2 2024: $142.2MQ3 2024: $193.4MQ4 2024: $735.8MQ1 2025: $533.2MQ2 2025: $738.3MQ3 2025: $3.23BQ4 2025: $1.48BQ1 2026: $972.4MQ2 2026: $3.02B
Institutions holding QURE and their total value by quarter
QuarterHoldersValue
Q2 2026254$3.02B
Q1 2026214$972.4M
Q4 2025226$1.48B
Q3 2025219$3.23B
Q2 2025143$738.3M
Q1 2025141$533.2M
Q4 2024138$735.8M
Q3 2024131$193.4M
Q2 2024117$142.2M
Q1 2024132$168.5M
Q4 2023144$255.8M
Q3 2023160$240.1M
Q2 2023178$412.8M
Q1 2023175$838.6M
Q4 2022178$912.1M
Q3 2022162$788.8M
Q2 2022169$756.3M
Q1 2022175$685.7M
Q4 2021177$783.5M
Q3 2021176$1.19B
Q2 2021156$1.11B
Q1 2021156$1.22B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding uniQure N.V.; share changes are against Q3 2025.

Institutions holding QURE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
NBC Securities, Inc.2$470.00%+2New
Huntington National Bank2$480.00%00.0%Unchanged
First Horizon Corp3$720.00%−383−99.2%Reduced
Northwestern Mutual Wealth Management Co3$720.00%+3New
Montag A & Associates Inc5$1180.00%+5New
SRS Capital Advisors, Inc.6$1440.00%−61−91.0%Reduced
Larson Financial Group LLC8$1910.00%00.0%Unchanged
GAMMA Investing LLC8$1910.00%+4+100.0%Added
WPG Advisers, LLC10$2390.00%−186−94.9%Reduced
CoreCap Advisors, LLC19$4550.00%+19New
MAI Capital Management28$6710.00%+17+154.5%Added
Cullen/Frost Bankers, Inc.34$8140.00%+34New
Cape Investment Advisory, Inc.40$9570.00%+40New
Motiv8 Investments LLC45$1.00K0.00%+45New
Greenline Wealth Management LLC52$1.24K0.00%+52New
Global Retirement Partners, LLC67$1.60K0.00%−233−77.7%Reduced
Transamerica Financial Advisors, Inc.71$1.70K0.00%+71New
Tower Research Capital LLC (TRC)76$1.82K0.00%−966−92.7%Reduced
Versant Capital Management, Inc85$2.03K0.00%−80−48.5%Reduced
Basecamp Wealth Advisors LLC91$2.18K0.00%+91New
Toth Financial Advisory Corp100$2.39K0.00%−65−39.4%Reduced
EverSource Wealth Advisors, LLC109$2.61K0.00%00.0%Unchanged
ORG Partners LLC114$2.72K0.00%+114New
Farther Finance Advisors, LLC114$2.73K0.00%+114New
State of Wyoming161$3.85K0.00%+161New
Daiwa Securities Group Inc.158$4.00K0.00%00.0%Unchanged
Allworth Financial LP174$4.16K0.00%00.0%Unchanged
Quadrant Capital Group LLC187$4.47K0.00%00.0%Unchanged
Entrust Financial LLC190$4.55K0.00%+190New
Umb Bank N A200$4.79K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.247$5.91K0.00%−753−75.3%Reduced
Signaturefd, LLC249$5.96K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC250$5.98K0.00%00.0%Unchanged
CWM, LLC247$6.00K0.00%00.0%Unchanged
SBI Securities Co., Ltd.280$6.70K0.00%−858−75.4%Reduced
Cygnus Capital Advisors, LLC288$7.00K0.01%+288New
Jones Financial Companies LLLP418$10.0K0.00%−191−31.4%Reduced
Advisor Group Holdings, Inc.587$14.0K0.00%+476+428.8%Added
Comerica Bank637$15.2K0.00%+230+56.5%Added
Parallel Advisors, LLC848$20.3K0.00%+848New
CIBC Private Wealth Group, LLC850$20.3K0.00%00.0%Unchanged
Torren Management, LLC1,169$28.0K0.01%+1,169New
GF Fund Management Co. Ltd.1,223$29.3K0.00%+43+3.6%Added
Smartleaf Asset Management LLC2,000$47.6K0.00%+2,000New
IFP Advisors, Inc1,989$47.6K0.00%+1,989New
FNY Investment Advisers, LLC2,080$49.0K0.01%+426+25.8%Added
Mirae Asset Global Investments Co., Ltd.3,027$72.4K0.00%+906+42.7%Added
Ensign Peak Advisors, Inc3,650$87.3K0.00%+650+21.7%Added
Knott David M Jr4,000$95.7K0.04%+2,000+100.0%Added
Deutsche Bank AG4,621$110.6K0.00%+2,291+98.3%Added
Bellevue Group AG4,763$114.0K0.00%00.0%Unchanged
Activest Wealth Management5,000$119.7K0.02%00.0%Unchanged
Quantbot Technologies LP5,444$130.3K0.00%+5,444New
US Bancorp6,171$147.7K0.00%+5,466+775.3%Added
Walleye Trading LLC7,657$183.2K0.00%−39,664−83.8%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.8,098$189.4K0.00%−7,352−47.6%Reduced
Cetera Investment Advisers8,366$200.2K0.00%+8,366New
KLP Kapitalforvaltning AS8,400$201.0K0.00%00.0%Unchanged
Mraz, Amerine & Associates, Inc.8,495$203.3K0.03%−824−8.8%Reduced
Militia Capital Partners, LP8,500$203.4K0.08%−26,500−75.7%Reduced
Rangeley Capital, LLC8,500$203.4K0.18%+8,500New
Seven Fleet Capital Management LP8,742$209.2K0.14%+8,742New
Graham Capital Management, L.P.9,013$215.7K0.01%+9,013New
Pavaki Capital Management LLC9,810$234.8K0.16%+9,810New
Quinn Opportunity Partners LLC10,000$239.3K0.01%−97,600−90.7%Reduced
Ashford Capital Management Inc10,000$239.3K0.03%+10,000New
China Universal Asset Management Co., Ltd.10,150$242.9K0.02%+533+5.5%Added
Scientech Research LLC10,203$244.2K0.15%−19,092−65.2%Reduced
Sassicaia Capital Advisers LLC10,400$248.9K0.55%−5,600−35.0%Reduced
Brinker Capital Investments, LLC10,768$257.7K0.00%+10,768New
Persistent Asset Partners Ltd11,014$263.6K0.13%+11,014New
Arizona State Retirement System11,141$266.6K0.00%+627+6.0%Added
Diametric Capital, LP11,822$282.9K0.08%+6,439+119.6%Added
Vontobel Holding Ltd.11,933$285.6K0.00%+11,933New
JustInvest LLC12,356$295.7K0.00%−83−0.7%Reduced
Lighthouse Investment Partners, LLC12,500$299.1K0.01%+12,500New
Freestone Grove Partners LP12,984$310.7K0.00%+12,984New
FORA Capital, LLC13,313$318.6K0.04%+13,313New
Lido Advisors, LLC5,544$323.6K0.00%00.0%Unchanged
Virtus Investment Advisers, Inc.13,636$326.3K0.09%+6,520+91.6%Added
SEI Investments Co13,938$333.4K0.00%−53,335−79.3%Reduced
Farallon Capital Management, L.L.C.14,000$335.0K0.00%−551,000−97.5%Reduced
Lion Point Capital, LP14,700$351.8K1.82%+14,700New
Handelsbanken Fonder AB14,900$357.0K0.00%+14,900New
Nomura Holdings Inc15,584$372.9K0.00%+15,584New
Prelude Capital Management, LLC15,739$376.6K0.03%+3,579+29.4%Added
Qsemble Capital Management, LP15,931$381.2K0.03%+15,931New
Manufacturers Life Insurance Company, The16,462$391.5K0.00%−32,300−66.2%Reduced
Janus Henderson Group PLC16,900$404.3K0.00%−3,000−15.1%Reduced
Clear Harbor Asset Management, LLC16,900$404.4K0.03%+9,900+141.4%Added
Assetmark, Inc18,613$445.4K0.00%+18,613New
Zurcher Kantonalbank (Zurich Cantonalbank)19,007$454.8K0.00%−890−4.5%Reduced
State of Wisconsin Investment Board19,390$464.0K0.00%+15,822+443.4%Added
Burkehill Global Management, LP20,000$478.6K0.03%00.0%Unchanged
Voleon Capital Management LP20,243$484.4K0.01%+20,243New
J. Goldman & Co LP20,250$484.6K0.02%+20,250New
Marshall Wace, LLP21,159$506.3K0.00%−87,051−80.4%Reduced
LPL Financial LLC21,969$525.7K0.00%−24,145−52.4%Reduced
Russell Investments Group, Ltd.23,707$567.3K0.00%−126,144−84.2%Reduced
TD Asset Management Inc23,734$568.0K0.00%−71,410−75.1%Reduced