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Pliant Therapeutics, Inc.

PLRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001746473

No open-market purchases or sales by Pliant Therapeutics, Inc. insiders were filed in the last 90 days; 86 institutions reported holding it in 13F filings for Q2 2026, worth $54.8M in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Pliant Therapeutics, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
161
+11 vs. Q3 2024
Shares held
64.8M
+1.55M (+2.5%) vs. Q3 2024
Total value
$852.6M
+$145.2M (+20.5%) vs. Q3 2024
New holders
24
55 more added
Sold out
13
43 more reduced

1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PLRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 161 institutions
Q1 2021: 76 institutionsQ2 2021: 81 institutionsQ3 2021: 77 institutionsQ4 2021: 88 institutionsQ1 2022: 92 institutionsQ2 2022: 88 institutionsQ3 2022: 110 institutionsQ4 2022: 125 institutionsQ1 2023: 143 institutionsQ2 2023: 144 institutionsQ3 2023: 136 institutionsQ4 2023: 134 institutionsQ1 2024: 135 institutionsQ2 2024: 144 institutionsQ3 2024: 151 institutionsQ4 2024: 161 institutionsQ1 2025: 141 institutionsQ2 2025: 114 institutionsQ3 2025: 100 institutionsQ4 2025: 98 institutionsQ1 2026: 91 institutionsQ2 2026: 86 institutions
Value heldQ4 2024: $852.6M
Q1 2021: $1.21BQ2 2021: $893.6MQ3 2021: $512.8MQ4 2021: $416.5MQ1 2022: $222.1MQ2 2022: $241.5MQ3 2022: $948.1MQ4 2022: $864.1MQ1 2023: $1.50BQ2 2023: $1.05BQ3 2023: $1.04BQ4 2023: $1.14BQ1 2024: $971.3MQ2 2024: $687.2MQ3 2024: $710.6MQ4 2024: $852.6MQ1 2025: $78.5MQ2 2025: $59.7MQ3 2025: $74.7MQ4 2025: $57.0MQ1 2026: $62.5MQ2 2026: $54.8M
Institutions holding PLRX and their total value by quarter
QuarterHoldersValue
Q2 202686$54.8M
Q1 202691$62.5M
Q4 202598$57.0M
Q3 2025100$74.7M
Q2 2025114$59.7M
Q1 2025141$78.5M
Q4 2024161$852.6M
Q3 2024151$710.6M
Q2 2024144$687.2M
Q1 2024135$971.3M
Q4 2023134$1.14B
Q3 2023136$1.04B
Q2 2023144$1.05B
Q1 2023143$1.50B
Q4 2022125$864.1M
Q3 2022110$948.1M
Q2 202288$241.5M
Q1 202292$222.1M
Q4 202188$416.5M
Q3 202177$512.8M
Q2 202181$893.6M
Q1 202176$1.21B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Pliant Therapeutics, Inc.; share changes are against Q3 2024.

Institutions holding PLRX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Harbor Capital Advisors, Inc.95,801$1.26M0.06%+3,822+4.2%Added
Two Sigma Investments, LP97,078$1.28M0.00%−38,044−28.2%Reduced
American Century Companies Inc100,849$1.33M0.00%+9,944+10.9%Added
Barclays PLC101,823$1.34M0.00%−319,676−75.8%Reduced
Exome Asset Management LLC103,504$1.36M1.03%−46,096−30.8%Reduced
UBS Oconnor LLC103,563$1.36M0.03%+18,678+22.0%Added
Algert Global LLC107,603$1.42M0.03%+1,041+1.0%Added
Hennion & Walsh Asset Management, Inc.108,608$1.43M0.06%+16,634+18.1%Added
Royal Bank of Canada112,517$1.48M0.00%+6,947+6.6%Added
Rhenman & Partners Asset Management AB116,250$1.53M0.16%−4,000−3.3%Reduced
Bank of America Corp120,977$1.59M0.00%−506,719−80.7%Reduced
Woodline Partners LP127,295$1.68M0.01%+15,635+14.0%Added
Atom Investors LP130,448$1.72M0.21%+130,448New
ADAR1 Capital Management, LLC134,798$1.78M0.37%−111,330−45.2%Reduced
Two Sigma Advisers, LP135,700$1.79M0.00%−22,100−14.0%Reduced
UBS Asset Management Americas Inc139,574$1.84M0.00%+21,637+18.3%Added
Caption Management, LLC142,404$1.88M0.08%+142,404New
Rice Hall James & Associates, LLC160,522$2.11M0.12%+3,305+2.1%Added
Jane Street Group, LLC182,015$2.40M0.00%−4,711−2.5%Reduced
Bank of New York Mellon Corp184,382$2.43M0.00%−172−0.1%Reduced
JPMorgan Chase & Co197,251$2.60M0.00%+148,039+300.8%Added
Nuveen Asset Management, LLC206,947$2.73M0.00%−128,533−38.3%Reduced
ArrowMark Colorado Holdings LLC281,189$3.70M0.05%00.0%Unchanged
Sphera Funds Management Ltd.297,362$3.92M0.72%00.0%Unchanged
Integral Health Asset Management, LLC300,000$3.95M0.35%00.0%Unchanged
AXA S.A.346,941$4.57M0.01%−546−0.2%Reduced
Citadel Advisors LLC401,689$5.29M0.00%+366,635+1,045.9%Added
Rock Springs Capital Management LP404,796$5.33M0.20%+19,800+5.1%Added
Fernwood Investment Management, LLC425,424$5.60M1.95%−87,712−17.1%Reduced
Goldman Sachs Group Inc446,700$5.88M0.00%+99,303+28.6%Added
Charles Schwab Investment Management Inc459,384$6.05M0.00%+2,721+0.6%Added
Granahan Investment Management Inc527,147$6.94M0.29%−211,105−28.6%Reduced
Bessemer Group Inc532,174$7.01M0.01%00.0%Unchanged
Checkpoint Capital L.P.535,494$7.05M3.59%+155,494+40.9%Added
Dimensional Fund Advisors LP547,297$7.21M0.00%+91,131+20.0%Added
Northern Trust Corp555,600$7.32M0.00%+53,584+10.7%Added
UBS Group AG628,281$8.27M0.00%+397,973+172.8%Added
Adage Capital Partners GP, L.L.C.649,660$8.56M0.01%+649,660New
Logos Global Management LP750,000$9.88M1.16%+750,000New
Morgan Stanley782,004$10.3M0.00%−35,119−4.3%Reduced
Candriam Luxembourg S.C.A.900,104$11.9M0.07%+66,888+8.0%Added
Franklin Resources Inc1,045,577$13.8M0.00%+5,673+0.5%Added
Great Point Partners LLC1,055,000$13.9M6.55%−855,121−44.8%Reduced
Frazier Life Sciences Management, L.P.1,120,803$14.8M0.61%+1,120,803New
Pictet Asset Management Holding SA1,266,030$16.7M0.02%−13,687−1.1%Reduced
Ra Capital Management, L.P.1,281,000$16.9M0.22%00.0%Unchanged
Silverarc Capital Management, LLC1,315,601$17.3M3.87%+1,315,601New
Geode Capital Management, LLC1,316,648$17.3M0.00%−1,660−0.1%Reduced
State Street Corp1,385,236$18.2M0.00%−17,494−1.2%Reduced
First Light Asset Management, LLC1,681,110$22.1M2.12%−894,436−34.7%Reduced
Polar Capital Holdings Plc2,015,000$26.5M0.15%00.0%Unchanged
TRV GP IV, LLC2,132,867$28.1M35.03%00.0%Unchanged
Deutsche Bank AG2,551,865$33.6M0.01%+1,017,500+66.3%Added
Blue Owl Capital Holdings LP2,769,199$36.5M8.62%−235,000−7.8%Reduced
Redmile Group, LLC2,895,478$38.1M2.66%−302,013−9.4%Reduced
Paradigm Biocapital Advisors LP3,197,050$42.1M1.46%+92,564+3.0%Added
Vanguard Group Inc3,228,755$42.5M0.00%−297,759−8.4%Reduced
FMR LLC3,876,598$51.1M0.00%−22,883−0.6%Reduced
Price T Rowe Associates Inc4,634,486$61.0M0.01%−200,327−4.1%Reduced
BlackRock, Inc.5,179,977$68.2M0.00%−38,988−0.7%Reduced
Deep Track Capital, LP5,972,257$78.7M2.95%00.0%Unchanged
Millennium Management LLC0$00.00%−244,640−100.0%Sold out
Capital International Investors0$00.00%−224,997−100.0%Sold out
Natixis0$00.00%−55,000−100.0%Sold out
HarbourVest Partners LLC0$00.00%−49,434−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−34,611−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−30,471−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−22,628−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−13,986−100.0%Sold out
Engineers Gate Manager LP0$00.00%−12,229−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−10,260−100.0%Sold out
Profund Advisors LLC0$00.00%−10,077−100.0%Sold out
Northwestern Mutual Wealth Management Co0$00.00%−30−100.0%Sold out
National Bank of Canada0$00.00%−8−100.0%Sold out
Mass General Brigham, Inc––––Not filed