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Pliant Therapeutics, Inc.

PLRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001746473

No open-market purchases or sales by Pliant Therapeutics, Inc. insiders were filed in the last 90 days; 86 institutions reported holding it in 13F filings for Q2 2026, worth $54.8M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Pliant Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
100
−13 vs. Q2 2025
Shares held
50.4M
−884.8K (−1.7%) vs. Q2 2025
Total value
$74.7M
+$15.2M (+25.5%) vs. Q2 2025
New holders
13
22 more added
Sold out
26
42 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PLRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 100 institutions
Q1 2021: 76 institutionsQ2 2021: 81 institutionsQ3 2021: 77 institutionsQ4 2021: 88 institutionsQ1 2022: 92 institutionsQ2 2022: 88 institutionsQ3 2022: 110 institutionsQ4 2022: 125 institutionsQ1 2023: 143 institutionsQ2 2023: 144 institutionsQ3 2023: 136 institutionsQ4 2023: 134 institutionsQ1 2024: 135 institutionsQ2 2024: 144 institutionsQ3 2024: 151 institutionsQ4 2024: 161 institutionsQ1 2025: 141 institutionsQ2 2025: 114 institutionsQ3 2025: 100 institutionsQ4 2025: 98 institutionsQ1 2026: 91 institutionsQ2 2026: 86 institutions
Value heldQ3 2025: $74.7M
Q1 2021: $1.21BQ2 2021: $893.6MQ3 2021: $512.8MQ4 2021: $416.5MQ1 2022: $222.1MQ2 2022: $241.5MQ3 2022: $948.1MQ4 2022: $864.1MQ1 2023: $1.50BQ2 2023: $1.05BQ3 2023: $1.04BQ4 2023: $1.14BQ1 2024: $971.3MQ2 2024: $687.2MQ3 2024: $710.6MQ4 2024: $852.6MQ1 2025: $78.5MQ2 2025: $59.7MQ3 2025: $74.7MQ4 2025: $57.0MQ1 2026: $62.5MQ2 2026: $54.8M
Institutions holding PLRX and their total value by quarter
QuarterHoldersValue
Q2 202686$54.8M
Q1 202691$62.5M
Q4 202598$57.0M
Q3 2025100$74.7M
Q2 2025114$59.7M
Q1 2025141$78.5M
Q4 2024161$852.6M
Q3 2024151$710.6M
Q2 2024144$687.2M
Q1 2024135$971.3M
Q4 2023134$1.14B
Q3 2023136$1.04B
Q2 2023144$1.05B
Q1 2023143$1.50B
Q4 2022125$864.1M
Q3 2022110$948.1M
Q2 202288$241.5M
Q1 202292$222.1M
Q4 202188$416.5M
Q3 202177$512.8M
Q2 202181$893.6M
Q1 202176$1.21B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Pliant Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding PLRX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Tang Capital Management LLC6,003,446$8.89M0.34%+3,446+0.1%Added
Woodline Partners LP4,504,817$6.67M0.03%+2,156,291+91.8%Added
Point72 Asset Management, L.P.4,338,394$6.42M0.01%+4,338,394New
Morgan Stanley3,507,288$5.19M0.00%−246,325−6.6%Reduced
Blue Owl Capital Holdings LP2,969,199$4.39M1.36%00.0%Unchanged
Vanguard Group Inc2,775,938$4.11M0.00%−226,410−7.5%Reduced
Acadian Asset Management LLC2,369,542$3.50M0.01%+739,129+45.3%Added
Citadel Advisors LLC2,339,468$3.46M0.00%−16,431−0.7%Reduced
JPMorgan Chase & Co2,130,489$3.15M0.00%+172,056+8.8%Added
Redmile Group, LLC1,591,695$2.36M0.23%−40,882−2.5%Reduced
BlackRock, Inc.1,420,863$2.10M0.00%−709,656−33.3%Reduced
UBS Group AG1,322,017$1.96M0.00%−1,324,539−50.0%Reduced
Peapod Lane Capital LLC1,097,028$1.62M1.45%+203,298+22.7%Added
Two Sigma Advisers, LP1,072,500$1.59M0.00%+617,300+135.6%Added
Renaissance Technologies LLC1,011,802$1.50M0.00%+811,854+406.0%Added
Great Point Partners LLC850,000$1.26M0.53%00.0%Unchanged
Eversept Partners, LP824,594$1.22M0.09%+824,594New
Monaco Asset Management SAM822,693$1.22M0.45%+120,300+17.1%Added
Two Sigma Investments, LP783,255$1.16M0.00%+505,097+181.6%Added
Bank of America Corp708,056$1.05M0.00%+227,526+47.3%Added
Geode Capital Management, LLC587,409$869.8K0.00%+4,823+0.8%Added
Goldman Sachs Group Inc555,076$821.5K0.00%−41,622−7.0%Reduced
Millennium Management LLC537,337$795.3K0.00%−313,137−36.8%Reduced
Bessemer Group Inc532,079$787.0K0.00%−390.0%Reduced
XTX Topco Ltd466,984$691.1K0.04%+37,974+8.9%Added
Jane Street Group, LLC380,327$562.9K0.00%+56,915+17.6%Added
Barclays PLC369,556$546.9K0.00%+356,670+2,767.9%Added
Jacobs Levy Equity Management, Inc367,113$543.3K0.00%+367,113New
Marshall Wace, LLP299,461$443.2K0.00%+299,461New
SEI Investments Co297,291$440.0K0.00%00.0%Unchanged
Stonepine Capital Management, LLC289,237$428.1K0.35%+289,237New
ArrowMark Colorado Holdings LLC281,189$416.2K0.01%00.0%Unchanged
State Street Corp253,834$375.7K0.00%00.0%Unchanged
HighMark Wealth Management LLC219,000$324.1K0.14%+78,000+55.3%Added
BNP Paribas Arbitrage, SA182,356$269.9K0.00%+27,665+17.9%Added
Gsa Capital Partners LLP160,884$238.0K0.02%+146,742+1,037.6%Added
Dimensional Fund Advisors LP151,673$224.5K0.00%−164,214−52.0%Reduced
Voleon Capital Management LP149,041$220.6K0.01%+149,041New
Rice Hall James & Associates, LLC144,843$214.4K0.01%−16,405−10.2%Reduced
Northern Trust Corp136,500$202.0K0.00%−28,940−17.5%Reduced
Torno Capital, LLC130,916$193.8K0.03%+130,916New
Advisor Group Holdings, Inc.125,376$185.6K0.00%+115,262+1,139.6%Added
Invesco Ltd.107,096$158.5K0.00%+33,602+45.7%Added
Algert Global LLC104,382$154.5K0.00%+15,692+17.7%Added
Bond & Devick Financial Network, Inc.100,160$148.2K0.04%00.0%Unchanged
Hennion & Walsh Asset Management, Inc.98,034$145.1K0.01%−1,785−1.8%Reduced
Bridgeway Capital Management, LLC82,300$121.8K0.00%00.0%Unchanged
Susquehanna International Group, LLP73,954$109.5K0.00%−96,032−56.5%Reduced
Rangeley Capital, LLC60,220$89.1K0.08%00.0%Unchanged
Catalyst Funds Management Pty Ltd59,539$88.1K0.01%+25,524+75.0%Added
Federated Hermes, Inc.55,296$81.8K0.00%−30,125−35.3%Reduced
Cubist Systematic Strategies, LLC54,367$80.5K0.00%−213,986−79.7%Reduced
Qube Research & Technologies Ltd49,515$73.3K0.00%−102,147−67.4%Reduced
Bluefin Capital Management, LLC–$61.0K0.03%–New
DekaBank Deutsche Girozentrale40,000$57.0K0.00%00.0%Unchanged
Quadrature Capital Ltd37,595$55.5K0.00%−23,626−38.6%Reduced
JustInvest LLC34,743$51.4K0.00%−797−2.2%Reduced
Squarepoint Ops LLC33,842$50.1K0.00%−124,002−78.6%Reduced
Tudor Investment Corp Et Al29,729$44.0K0.00%00.0%Unchanged
Jain Global LLC25,037$37.1K0.00%−116,460−82.3%Reduced
FNY Investment Advisers, LLC25,400$37.0K0.01%+25,400New
Connor, Clark & Lunn Investment Management Ltd.24,340$36.0K0.00%+24,340New
Engineers Gate Manager LP23,488$34.8K0.00%−7,935−25.3%Reduced
Blackstone Group Inc.22,206$32.9K0.00%00.0%Unchanged
Point72 Asia (Singapore) Pte. Ltd.21,905$32.4K0.01%−26,102−54.4%Reduced
Tower Research Capital LLC (TRC)20,749$30.7K0.00%−2,561−11.0%Reduced
Prosight Management, LP20,487$30.3K0.01%−816,913−97.6%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH18,065$26.7K0.00%00.0%Unchanged
SG Americas Securities, LLC16,783$25.0K0.00%−12,582−42.8%Reduced
Royal Bank of Canada16,175$24.0K0.00%−28,457−63.8%Reduced
Bank of New York Mellon Corp15,933$23.6K0.00%−102−0.6%Reduced
Simplex Trading, LLC12,989$19.0K0.00%−297−2.2%Reduced
Quest Partners LLC11,716$17.3K0.00%00.0%Unchanged
Fiduciary Trust Co11,620$17.2K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.10,760$15.9K0.00%−1,569−12.7%Reduced
FMR LLC4,974$7.36K0.00%−1,533−23.6%Reduced
Citigroup Inc4,319$6.39K0.00%−19,605−81.9%Reduced
Group One Trading, L.P.3,121$4.62K0.00%−1,500−32.5%Reduced
Rhumbline Advisers2,379$3.52K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.2,373$3.51K0.00%+2+0.1%Added
Caitong International Asset Management Co., Ltd2,047$3.03K0.00%−3,501−63.1%Reduced
Russell Investments Group, Ltd.1,406$2.08K0.00%−867−38.1%Reduced
Fortitude Family Office, LLC1,278$1.89K0.00%+1,278New
GF Fund Management Co. Ltd.1,264$1.87K0.00%−245−16.2%Reduced
Rockefeller Capital Management L.P.1,085$1.61K0.00%+1,085New
The PNC Financial Services Group, Inc.984$1.46K0.00%−735−42.8%Reduced
Rise Advisors, LLC740$1.09K0.00%00.0%Unchanged
CWM, LLC657$1.00K0.00%−2,643−80.1%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)606$8970.00%−265−30.4%Reduced
MAI Capital Management400$5920.00%00.0%Unchanged
SBI Securities Co., Ltd.320$4740.00%00.0%Unchanged
Bell Investment Advisors, Inc307$4550.00%+307New
Point72 (DIFC) Ltd112$1660.00%−6,996−98.4%Reduced
Wells Fargo & Company50$740.00%−2,279−97.9%Reduced
Truvestments Capital LLC50$740.00%−117−70.1%Reduced
Comerica Bank14$210.00%00.0%Unchanged
Farther Finance Advisors, LLC5$70.00%00.0%Unchanged
Global Retirement Partners, LLC4$60.00%00.0%Unchanged
Daiwa Securities Group Inc.196$00.00%00.0%Unchanged
Covestor Ltd46$00.00%00.0%Unchanged