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Pacific Biosciences of California, Inc.

PACB
Exchange
Nasdaq
Industry
Laboratory Analytical Instruments
SEC CIK
0001299130

In the last 90 days, Pacific Biosciences of California, Inc. insiders filed 0 open-market purchases and 1 sale; 223 institutions reported holding it in 13F filings for Q2 2026, worth $320.8M in total; superinvestors ARK Invest and HHLR Advisors (Hillhouse) hold it.

13F holders, Q4 2025

Institutional positions in Pacific Biosciences of California, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
216
+12 vs. Q3 2025
Shares held
200.7M
+18.9M (+10.4%) vs. Q3 2025
Total value
$373.5M
+$141.3M (+60.8%) vs. Q3 2025
New holders
43
69 more added
Sold out
31
50 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PACB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 216 institutions
Q1 2021: 263 institutionsQ2 2021: 261 institutionsQ3 2021: 246 institutionsQ4 2021: 256 institutionsQ1 2022: 250 institutionsQ2 2022: 230 institutionsQ3 2022: 227 institutionsQ4 2022: 237 institutionsQ1 2023: 260 institutionsQ2 2023: 272 institutionsQ3 2023: 275 institutionsQ4 2023: 274 institutionsQ1 2024: 268 institutionsQ2 2024: 229 institutionsQ3 2024: 226 institutionsQ4 2024: 227 institutionsQ1 2025: 225 institutionsQ2 2025: 207 institutionsQ3 2025: 208 institutionsQ4 2025: 216 institutionsQ1 2026: 231 institutionsQ2 2026: 223 institutions
Value heldQ4 2025: $373.5M
Q1 2021: $5.47BQ2 2021: $6.04BQ3 2021: $4.83BQ4 2021: $4.20BQ1 2022: $2.03BQ2 2022: $1.03BQ3 2022: $1.23BQ4 2022: $1.84BQ1 2023: $2.93BQ2 2023: $3.37BQ3 2023: $2.20BQ4 2023: $2.76BQ1 2024: $1.01BQ2 2024: $331.9MQ3 2024: $394.3MQ4 2024: $475.1MQ1 2025: $265.6MQ2 2025: $245.8MQ3 2025: $237.8MQ4 2025: $373.5MQ1 2026: $248.5MQ2 2026: $320.8M
Institutions holding PACB and their total value by quarter
QuarterHoldersValue
Q2 2026223$320.8M
Q1 2026231$248.5M
Q4 2025216$373.5M
Q3 2025208$237.8M
Q2 2025207$245.8M
Q1 2025225$265.6M
Q4 2024227$475.1M
Q3 2024226$394.3M
Q2 2024229$331.9M
Q1 2024268$1.01B
Q4 2023274$2.76B
Q3 2023275$2.20B
Q2 2023272$3.37B
Q1 2023260$2.93B
Q4 2022237$1.84B
Q3 2022227$1.23B
Q2 2022230$1.03B
Q1 2022250$2.03B
Q4 2021256$4.20B
Q3 2021246$4.83B
Q2 2021261$6.04B
Q1 2021263$5.47B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Pacific Biosciences of California, Inc.; share changes are against Q3 2025.

Institutions holding PACB in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Ameritas Investment Partners, Inc.26,094$48.8K0.00%00.0%Unchanged
Atria Investments LLC27,496$51.4K0.00%+5,735+26.4%Added
Sandbox Financial Partners, LLC27,517$51.5K0.01%00.0%Unchanged
Axxcess Wealth Management, LLC28,603$53.5K0.00%−257−0.9%Reduced
FMR LLC29,855$55.8K0.00%+11,279+60.7%Added
Ambassador Advisors, LLC30,000$56.1K0.01%00.0%Unchanged
Citigroup Inc30,200$56.5K0.00%+10,620+54.2%Added
Venture Visionary Partners LLC30,300$56.7K0.00%00.0%Unchanged
Hartline Investment Corp31,000$58.0K0.01%00.0%Unchanged
Victory Capital Management Inc31,184$58.3K0.00%+725+2.4%Added
Magnetar Financial LLC31,602$59.1K0.00%+31,602New
Jump Financial, LLC33,746$63.1K0.00%+33,746New
JustInvest LLC33,880$63.4K0.00%−675−2.0%Reduced
Kestra Advisory Services, LLC34,858$65.2K0.00%+652+1.9%Added
Sanctuary Advisors, LLC34,880$65.2K0.00%+3,371+10.7%Added
Western Wealth Management, LLC35,345$66.1K0.00%−5,000−12.4%Reduced
Polymer Capital Management (US) LLC37,558$70.2K0.01%+37,558New
Wealthfront Advisers LLC38,041$71.1K0.00%−52,164−57.8%Reduced
Mariner, LLC40,004$74.8K0.00%+28,608+251.0%Added
Captrust Financial Advisors42,959$80.3K0.00%+42,959New
Wealth Architects, LLC48,725$91.1K0.01%00.0%Unchanged
Cetera Investment Advisers48,943$91.5K0.00%−101,238−67.4%Reduced
China Universal Asset Management Co., Ltd.49,196$92.0K0.01%−3,454−6.6%Reduced
Evolution Wealth Advisors, LLC50,000$93.5K0.01%00.0%Unchanged
Kestra Private Wealth Services, LLC51,200$95.7K0.00%+1,300+2.6%Added
Voya Investment Management LLC51,548$96.4K0.00%00.0%Unchanged
HSBC Holdings PLC52,708$97.8K0.00%+52,708New
IFP Advisors, Inc52,787$98.7K0.00%−42,825−44.8%Reduced
Clear Harbor Asset Management, LLC58,710$109.8K0.01%−66,584−53.1%Reduced
TCG Advisory Services, LLC61,900$115.8K0.00%00.0%Unchanged
ProShare Advisors LLC63,799$119.3K0.00%+5,883+10.2%Added
BNP Paribas Arbitrage, SA66,055$123.5K0.00%+7,729+13.3%Added
Stifel Financial Corp70,860$132.5K0.00%+16,151+29.5%Added
State Board of Administration of Florida Retirement System71,941$134.5K0.00%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey79,955$149.5K0.00%−1,193−1.5%Reduced
Steel Peak Wealth Management LLC81,422$152.3K0.01%+51,492+172.0%Added
Manufacturers Life Insurance Company, The82,527$154.3K0.00%−11,315−12.1%Reduced
New York State Common Retirement Fund84,825$158.6K0.00%00.0%Unchanged
AQR Capital Management LLC86,964$162.6K0.00%+35,629+69.4%Added
American Century Companies Inc94,063$175.9K0.00%+94,063New
Gabelli Funds LLC100,000$187.0K0.00%00.0%Unchanged
Abacus Planning Group, Inc.100,000$187.0K0.02%00.0%Unchanged
SG Americas Securities, LLC100,751$188.0K0.00%+30,078+42.6%Added
Envestnet Asset Management Inc104,621$195.6K0.00%−36,347−25.8%Reduced
Abacus Wealth Partners, LLC113,889$213.0K0.02%+113,889New
MetLife Investment Management116,188$217.3K0.00%−20,728−15.1%Reduced
Koa Wealth Management, LLC120,000$224.4K0.15%00.0%Unchanged
Benjamin Edwards Inc121,926$227.9K0.00%−11,951−8.9%Reduced
Intech Investment Management LLC123,936$231.8K0.00%−8,432−6.4%Reduced
Bank of Montreal126,923$237.3K0.00%+18,353+16.9%Added
AdvisorNet Financial, Inc133,767$250.1K0.01%+7,950+6.3%Added
Farallon Capital Management, L.L.C.135,000$252.4K0.00%00.0%Unchanged
Polen Capital Management LLC137,149$256.5K0.00%+137,149New
DekaBank Deutsche Girozentrale73,300$296.0K0.00%00.0%Unchanged
Price T Rowe Associates Inc163,527$306.0K0.00%+17,663+12.1%Added
Raymond James Financial Inc183,278$342.7K0.00%+21,413+13.2%Added
Green Alpha Advisors, LLC183,466$343.1K0.31%+9,441+5.4%Added
Graham Capital Management, L.P.188,485$352.5K0.01%+188,485New
Quadrature Capital Ltd206,410$386.0K0.00%−145,945−41.4%Reduced
Deutsche Bank AG218,981$409.5K0.00%+10,107+4.8%Added
Scientech Research LLC252,887$472.9K0.30%+252,887New
LPL Financial LLC274,247$512.8K0.00%+60,124+28.1%Added
Gsa Capital Partners LLP305,177$571.0K0.05%−104,193−25.5%Reduced
Wells Fargo & Company314,014$587.2K0.00%+82,059+35.4%Added
Dimensional Fund Advisors LP323,749$603.5K0.00%−39,074−10.8%Reduced
Mirae Asset Global ETFs Holdings Ltd.325,139$608.0K0.00%−110.0%Reduced
Rhumbline Advisers360,963$675.0K0.00%−54,716−13.2%Reduced
Alliancebernstein L.P.387,060$723.8K0.00%00.0%Unchanged
Acadian Asset Management LLC441,250$822.0K0.00%+418,134+1,808.9%Added
Squarepoint Ops LLC448,558$838.8K0.00%−483,518−51.9%Reduced
JPMorgan Chase & Co456,908$854.4K0.00%−11,972−2.6%Reduced
Group One Trading, L.P.460,250$860.7K0.03%+5,382+1.2%Added
ArrowMark Colorado Holdings LLC468,382$875.9K0.02%00.0%Unchanged
Carret Asset Management, LLC470,000$878.9K0.08%+50,000+11.9%Added
Barclays PLC472,108$882.8K0.00%+72,201+18.1%Added
Birchview Capital, LP500,000$935.0K0.55%00.0%Unchanged
Creative Planning519,726$971.9K0.00%+200,876+63.0%Added
Vestmark Advisory Solutions, Inc.550,344$1.03M0.01%−51,179−8.5%Reduced
Mirador Capital Partners LP591,005$1.11M0.15%+9,612+1.7%Added
XTX Topco Ltd628,222$1.17M0.03%+615,907+5,001.3%Added
Caxton Associates LLP641,724$1.20M0.02%+641,724New
Headlands Technologies LLC733,840$1.37M0.11%+733,840New
Universal- Beteiligungs- und Servicegesellschaft mbH808,700$1.40M0.00%00.0%Unchanged
Two Sigma Advisers, LP827,500$1.55M0.00%+827,500New
Bank of New York Mellon Corp834,573$1.56M0.00%+29,017+3.6%Added
Nuveen, LLC848,219$1.59M0.00%+578,035+213.9%Added
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)918,892$1.72M0.06%00.0%Unchanged
Bourne Lent Asset Management Inc967,055$1.81M0.60%00.0%Unchanged
HRT Financial LP1,363,577$2.55M0.01%+1,363,577New
Goldman Sachs Group Inc1,378,872$2.58M0.00%+869,445+170.7%Added
Invesco Ltd.1,433,011$2.68M0.00%+326,238+29.5%Added
Jane Street Group, LLC1,500,518$2.81M0.00%+1,263,495+533.1%Added
Amiral Gestion2,733,290$3.21M1.18%00.0%Unchanged
Bank of America Corp1,854,814$3.47M0.00%+382,124+25.9%Added
Davy Global Fund Management Ltd1,894,931$3.54M0.24%+606,239+47.0%Added
Northern Trust Corp2,046,839$3.83M0.00%−242,057−10.6%Reduced
Morgan Stanley2,410,540$4.51M0.00%+1,959,325+434.2%Added
Charles Schwab Investment Management Inc2,465,853$4.61M0.00%+38,499+1.6%Added
Koss-Olinger Consulting, LLC2,600,000$4.86M0.38%−700,000−21.2%Reduced
Susquehanna International Group, LLP2,611,543$4.88M0.01%+1,236,284+89.9%Added