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Pacific Biosciences of California, Inc.

PACB
Exchange
Nasdaq
Industry
Laboratory Analytical Instruments
SEC CIK
0001299130

In the last 90 days, Pacific Biosciences of California, Inc. insiders filed 0 open-market purchases and 1 sale; 223 institutions reported holding it in 13F filings for Q2 2026, worth $320.8M in total; superinvestors ARK Invest and HHLR Advisors (Hillhouse) hold it.

13F holders, Q1 2022

Institutional positions in Pacific Biosciences of California, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
250
−4 vs. Q4 2021
Shares held
223.1M
+17.8M (+8.7%) vs. Q4 2021
Total value
$2.03B
−$2.17B (−51.6%) vs. Q4 2021
New holders
44
93 more added
Sold out
48
70 more reduced

2 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PACB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 250 institutions
Q1 2021: 263 institutionsQ2 2021: 261 institutionsQ3 2021: 246 institutionsQ4 2021: 256 institutionsQ1 2022: 250 institutionsQ2 2022: 230 institutionsQ3 2022: 227 institutionsQ4 2022: 237 institutionsQ1 2023: 260 institutionsQ2 2023: 272 institutionsQ3 2023: 275 institutionsQ4 2023: 274 institutionsQ1 2024: 268 institutionsQ2 2024: 229 institutionsQ3 2024: 226 institutionsQ4 2024: 227 institutionsQ1 2025: 225 institutionsQ2 2025: 207 institutionsQ3 2025: 208 institutionsQ4 2025: 216 institutionsQ1 2026: 231 institutionsQ2 2026: 223 institutions
Value heldQ1 2022: $2.03B
Q1 2021: $5.47BQ2 2021: $6.04BQ3 2021: $4.83BQ4 2021: $4.20BQ1 2022: $2.03BQ2 2022: $1.03BQ3 2022: $1.23BQ4 2022: $1.84BQ1 2023: $2.93BQ2 2023: $3.37BQ3 2023: $2.20BQ4 2023: $2.76BQ1 2024: $1.01BQ2 2024: $331.9MQ3 2024: $394.3MQ4 2024: $475.1MQ1 2025: $265.6MQ2 2025: $245.8MQ3 2025: $237.8MQ4 2025: $373.5MQ1 2026: $248.5MQ2 2026: $320.8M
Institutions holding PACB and their total value by quarter
QuarterHoldersValue
Q2 2026223$320.8M
Q1 2026231$248.5M
Q4 2025216$373.5M
Q3 2025208$237.8M
Q2 2025207$245.8M
Q1 2025225$265.6M
Q4 2024227$475.1M
Q3 2024226$394.3M
Q2 2024229$331.9M
Q1 2024268$1.01B
Q4 2023274$2.76B
Q3 2023275$2.20B
Q2 2023272$3.37B
Q1 2023260$2.93B
Q4 2022237$1.84B
Q3 2022227$1.23B
Q2 2022230$1.03B
Q1 2022250$2.03B
Q4 2021256$4.20B
Q3 2021246$4.83B
Q2 2021261$6.04B
Q1 2021263$5.47B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Pacific Biosciences of California, Inc.; share changes are against Q4 2021.

Institutions holding PACB in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Banque Pictet & Cie SA400,722$3.65M0.03%−3,634−0.9%Reduced
Engineers Gate Manager LP402,217$3.66M0.14%+389,169+2,982.6%Added
Granahan Investment Management Inc412,183$3.75M0.09%−76,712−15.7%Reduced
Guggenheim Capital LLC450,108$4.10M0.02%+31,330+7.5%Added
Polar Asset Management Partners Inc.476,500$4.34M0.05%+476,500New
Swiss National Bank495,546$4.51M0.00%+80,000+19.3%Added
Bourne Lent Asset Management Inc556,865$5.07M1.59%+1,115+0.2%Added
Bank of America Corp593,831$5.40M0.00%+137,847+30.2%Added
Cubist Systematic Strategies, LLC622,494$5.67M0.05%+577,366+1,279.4%Added
WCM Investment Management, LLC679,803$6.19M0.02%+341,557+101.0%Added
D. E. Shaw & Co., Inc.722,527$6.58M0.01%−461,687−39.0%Reduced
Squarepoint Ops LLC819,470$7.46M0.06%+800,175+4,147.1%Added
Voloridge Investment Management, LLC846,180$7.70M0.04%+846,180New
Renaissance Technologies LLC868,700$7.91M0.01%+868,700New
Bank of New York Mellon Corp997,044$9.07M0.00%−9,695−1.0%Reduced
JPMorgan Chase & Co1,015,819$9.24M0.00%+748,630+280.2%Added
Two Sigma Advisers, LP1,088,300$9.90M0.03%+705,900+184.6%Added
Nuveen Asset Management, LLC1,070,303$10.6M0.00%−102,415−8.7%Reduced
Oracle Investment Management Inc1,225,395$11.2M2.24%−195,257−13.7%Reduced
Norges Bank1,281,967$11.7M0.00%−444,602−25.8%Reduced
Decheng Capital Management III (Cayman), LLC1,463,872$13.3M4.08%+1,463,872New
FMR LLC1,479,433$13.5M0.00%−312,858−17.5%Reduced
Charles Schwab Investment Management Inc1,627,942$14.8M0.00%+36,617+2.3%Added
Farallon Capital Management, L.L.C.1,631,800$14.8M0.08%−413,688−20.2%Reduced
SB Management Ltd1,886,107$17.2M3.35%−6,270,000−76.9%Reduced
Morgan Stanley1,948,642$17.7M0.00%+840,967+75.9%Added
Northern Trust Corp1,979,768$18.0M0.00%−4,190−0.2%Reduced
Citadel Advisors LLC2,248,249$20.5M0.02%+1,893,895+534.5%Added
Millennium Management LLC2,436,902$22.2M0.03%+1,978,498+431.6%Added
Blue Water Life Science Advisors, LLC2,660,000$24.2M11.49%+2,660,000New
Goldman Sachs Group Inc2,904,619$26.4M0.01%+228,964+8.6%Added
Two Sigma Investments, LP3,088,155$28.1M0.08%+2,699,194+693.9%Added
Capital World Investors3,390,000$30.8M0.01%00.0%Unchanged
Macquarie Group Ltd3,841,026$35.0M0.03%+1,941,270+102.2%Added
Geode Capital Management, LLC3,842,564$35.0M0.00%+138,571+3.7%Added
SEI Investments Co3,936,287$35.8M0.07%+1,261,333+47.2%Added
State Street Corp4,428,965$40.3M0.00%+271,315+6.5%Added
Bellevue Group AG4,881,752$44.4M0.52%+3,328,729+214.3%Added
Baker Bros. Advisors LP5,444,963$49.5M0.28%00.0%Unchanged
Price T Rowe Associates Inc6,104,093$55.5M0.01%+270,289+4.6%Added
Casdin Capital, LLC7,990,652$72.7M3.26%00.0%Unchanged
Capital International Investors12,781,855$116.3M0.03%+675,537+5.6%Added
Sumitomo Mitsui Trust Holdings, Inc.14,021,205$127.6M0.08%+2,106,180+17.7%Added
Nikko Asset Management Americas, Inc.14,021,205$127.9M0.94%+2,106,180+17.7%Added
BlackRock Inc.16,609,353$151.1M0.00%+40,109+0.2%Added
Vanguard Group Inc19,945,092$181.5M0.00%+90,216+0.5%Added
Jackson Square Partners, LLC22,542,589$205.1M2.04%+8,039,420+55.4%Added
ARK Investment Management LLCSuperinvestorARK Invest27,259,521$248.1M1.04%+876,418+3.3%Added
Advisor Group Holdings, Inc.14,852––+330+2.3%Added
Sofos Investments, Inc.18––−22−55.0%Reduced
William Blair Investment Management, LLC0$00.00%−5,469,636−100.0%Sold out
Westfield Capital Management Co LP0$00.00%−858,583−100.0%Sold out
Pura Vida Investments, LLC0$00.00%−330,033−100.0%Sold out
Kennedy Capital Management, Inc.0$00.00%−220,106−100.0%Sold out
Alyeska Investment Group, L.P.0$00.00%−173,885−100.0%Sold out
Putnam Investments LLC0$00.00%−139,254−100.0%Sold out
SG Americas Securities, LLC0$00.00%−126,676−100.0%Sold out
Baker Chad R0$00.00%−82,875−100.0%Sold out
ClariVest Asset Management LLC0$00.00%−80,304−100.0%Sold out
Goldstream Capital Management Ltd0$00.00%−72,386−100.0%Sold out
Dimensional Fund Advisors LP0$00.00%−65,657−100.0%Sold out
AQR Capital Management LLC0$00.00%−62,416−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−50,096−100.0%Sold out
Assenagon Asset Management S.A.0$00.00%−48,822−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−27,560−100.0%Sold out
First Quadrant L P0$00.00%−27,200−100.0%Sold out
Connective Portfolio Management, LLC0$00.00%−26,960−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−26,309−100.0%Sold out
Skandinaviska Enskilda Banken AB (publ)0$00.00%−24,505−100.0%Sold out
GAM Holding AG0$00.00%−22,659−100.0%Sold out
Blair William & Co0$00.00%−17,079−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−16,475−100.0%Sold out
Harbor Capital Advisors, Inc.0$00.00%−15,596−100.0%Sold out
Hamilton Lane Advisors LLC0$00.00%−14,091−100.0%Sold out
STRS Ohio0$00.00%−13,200−100.0%Sold out
Pluribus Labs, LLC0$00.00%−12,130−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−11,536−100.0%Sold out
Titus Wealth Management0$00.00%−11,261−100.0%Sold out
V Wealth Advisors LLC0$00.00%−11,102−100.0%Sold out
Bank of Montreal0$00.00%−10,085−100.0%Sold out
Twin Tree Management, LP0$00.00%−7,412−100.0%Sold out
Vienna Asset Management LLC0$00.00%−7,366−100.0%Sold out
Belpointe Asset Management LLC0$00.00%−6,500−100.0%Sold out
KRS Capital Management, LLC0$00.00%−3,500−100.0%Sold out
Pacer Advisors, Inc.0$00.00%−3,049−100.0%Sold out
Credit Agricole S A0$00.00%−1,635−100.0%Sold out
TFC Financial Management0$00.00%−1,425−100.0%Sold out
First Horizon Advisors, Inc.0$00.00%−1,283−100.0%Sold out
Walleye Trading LLC0$00.00%−788−100.0%Sold out
CoreCap Advisors, LLC0$00.00%−785−100.0%Sold out
Total Clarity Wealth Management, Inc.0$00.00%−230−100.0%Sold out
JNBA Financial Advisors0$00.00%−201−100.0%Sold out
Spire Wealth Management0$00.00%−200−100.0%Sold out
Amplius Wealth Advisors, LLC0$00.00%−143−100.0%Sold out
Umb Bank N A0$00.00%−47−100.0%Sold out
Lee Financial Co0$00.00%−28−100.0%Sold out
Point72 Hong Kong Ltd0$00.00%−35−100.0%Sold out
Koshinski Asset Management, Inc.0$00.00%−20−100.0%Sold out
NEXT Financial Group, Inc––––Not filed
Bell Investment Advisors, Inc––––Not filed