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Pacific Biosciences of California, Inc.

PACB
Exchange
Nasdaq
Industry
Laboratory Analytical Instruments
SEC CIK
0001299130

In the last 90 days, Pacific Biosciences of California, Inc. insiders filed 0 open-market purchases and 1 sale; 223 institutions reported holding it in 13F filings for Q2 2026, worth $320.8M in total; superinvestors ARK Invest and HHLR Advisors (Hillhouse) hold it.

13F holders, Q4 2021

Institutional positions in Pacific Biosciences of California, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
256
+11 vs. Q3 2021
Shares held
205.4M
+16.4M (+8.7%) vs. Q3 2021
Total value
$4.20B
−$628.7M (−13.0%) vs. Q3 2021
New holders
51
87 more added
Sold out
40
79 more reduced

1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PACB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 256 institutions
Q1 2021: 263 institutionsQ2 2021: 261 institutionsQ3 2021: 246 institutionsQ4 2021: 256 institutionsQ1 2022: 250 institutionsQ2 2022: 230 institutionsQ3 2022: 227 institutionsQ4 2022: 237 institutionsQ1 2023: 260 institutionsQ2 2023: 272 institutionsQ3 2023: 275 institutionsQ4 2023: 274 institutionsQ1 2024: 268 institutionsQ2 2024: 229 institutionsQ3 2024: 226 institutionsQ4 2024: 227 institutionsQ1 2025: 225 institutionsQ2 2025: 207 institutionsQ3 2025: 208 institutionsQ4 2025: 216 institutionsQ1 2026: 231 institutionsQ2 2026: 223 institutions
Value heldQ4 2021: $4.20B
Q1 2021: $5.47BQ2 2021: $6.04BQ3 2021: $4.83BQ4 2021: $4.20BQ1 2022: $2.03BQ2 2022: $1.03BQ3 2022: $1.23BQ4 2022: $1.84BQ1 2023: $2.93BQ2 2023: $3.37BQ3 2023: $2.20BQ4 2023: $2.76BQ1 2024: $1.01BQ2 2024: $331.9MQ3 2024: $394.3MQ4 2024: $475.1MQ1 2025: $265.6MQ2 2025: $245.8MQ3 2025: $237.8MQ4 2025: $373.5MQ1 2026: $248.5MQ2 2026: $320.8M
Institutions holding PACB and their total value by quarter
QuarterHoldersValue
Q2 2026223$320.8M
Q1 2026231$248.5M
Q4 2025216$373.5M
Q3 2025208$237.8M
Q2 2025207$245.8M
Q1 2025225$265.6M
Q4 2024227$475.1M
Q3 2024226$394.3M
Q2 2024229$331.9M
Q1 2024268$1.01B
Q4 2023274$2.76B
Q3 2023275$2.20B
Q2 2023272$3.37B
Q1 2023260$2.93B
Q4 2022237$1.84B
Q3 2022227$1.23B
Q2 2022230$1.03B
Q1 2022250$2.03B
Q4 2021256$4.20B
Q3 2021246$4.83B
Q2 2021261$6.04B
Q1 2021263$5.47B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Pacific Biosciences of California, Inc.; share changes are against Q3 2021.

Institutions holding PACB in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
State Board of Administration of Florida Retirement System71,091$1.46M0.00%−640−0.9%Reduced
MetLife Investment Management69,267$1.42M0.01%00.0%Unchanged
AtonRa Partners69,095$1.41M0.49%−25,205−26.7%Reduced
Dimensional Fund Advisors LP65,657$1.34M0.00%+310+0.5%Added
Stifel Financial Corp65,253$1.33M0.00%−62,514−48.9%Reduced
Snowden Capital Advisors LLC63,802$1.30M0.07%−108,816−63.0%Reduced
DekaBank Deutsche Girozentrale66,600$1.28M0.00%+1,800+2.8%Added
AQR Capital Management LLC62,416$1.28M0.00%−75,003−54.6%Reduced
Royal Bank of Canada62,078$1.27M0.00%−18,802−23.2%Reduced
Fisher Asset Management, LLC54,892$1.12M0.00%+6,043+12.4%Added
Metropolitan Life Insurance Co51,430$1.05M0.01%00.0%Unchanged
Cresset Asset Management, LLC50,989$1.04M0.01%−16,118−24.0%Reduced
Arizona State Retirement System50,882$1.04M0.01%−451−0.9%Reduced
Allianz Asset Management GmbH50,096$1.02M0.00%−7,881−13.6%Reduced
Evolution Wealth Advisors, LLC50,000$1.02M0.18%00.0%Unchanged
Commonwealth Equity Services, LLC49,941$1.02M0.00%+29,338+142.4%Added
Assenagon Asset Management S.A.48,822$999.0K0.00%+16,281+50.0%Added
Principal Financial Group Inc48,236$986.0K0.00%−18,355−27.6%Reduced
Panagora Asset Management Inc45,963$940.0K0.00%−17,261−27.3%Reduced
Ensign Peak Advisors, Inc45,150$924.0K0.00%+45,150New
Cubist Systematic Strategies, LLC45,128$923.0K0.01%+45,128New
HSBC Holdings PLC43,034$880.0K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)42,428$868.0K0.00%+7,154+20.3%Added
Carnegie Capital Asset Management, LLC40,672$832.0K0.03%−3,300−7.5%Reduced
Handelsbanken Fonder AB40,300$825.0K0.00%+1,300+3.3%Added
Trellus Management Company, LLC40,000$818.0K0.96%+21,500+116.2%Added
Janus Henderson Group PLC37,431$765.0K0.00%+18,898+102.0%Added
Teacher Retirement System of Texas37,011$757.0K0.00%+7,450+25.2%Added
Profund Advisors LLC36,905$755.0K0.02%−1,056−2.8%Reduced
Victory Capital Management Inc31,331$641.0K0.00%−9,156−22.6%Reduced
Amalgamated Bank29,329$600.0K0.00%−291−1.0%Reduced
Janney Montgomery Scott LLC28,622$586.0K0.00%−86−0.3%Reduced
Ford Foundation28,181$577.0K0.41%+28,181New
American Portfolios Advisors28,156$576.1K0.02%+14,724+109.6%Added
Green Alpha Advisors, LLC28,047$574.0K0.39%+2,818+11.2%Added
Susquehanna Fundamental Investments, LLC27,560$564.0K0.01%−15,599−36.1%Reduced
First Quadrant L P27,200$557.0K0.06%00.0%Unchanged
Connective Portfolio Management, LLC26,960$552.0K0.97%+26,960New
AdvisorNet Financial, Inc26,672$546.0K0.03%−1,180−4.2%Reduced
Sciencast Management LP28,918$543.0K0.10%+28,918New
Public Employees Retirement Association of Colorado26,468$542.0K0.00%00.0%Unchanged
Balyasny Asset Management LLC26,309$538.0K0.00%+26,309New
Weiss Multi-Strategy Advisers LLC25,885$530.0K0.01%−115−0.4%Reduced
Laurel Wealth Advisors, Inc.25,243$516.0K0.04%−60−0.2%Reduced
Skandinaviska Enskilda Banken AB (publ)24,505$512.0K0.00%00.0%Unchanged
Pictet & Cie (Europe) SA24,393$499.0K0.02%+9,052+59.0%Added
Sandbox Financial Partners, LLC24,000$491.0K0.31%+24,000New
HarbourVest Partners LLC23,484$480.0K0.06%00.0%Unchanged
US Bancorp23,292$477.0K0.00%+4,462+23.7%Added
GAM Holding AG22,659$464.0K0.02%−7,011−23.6%Reduced
Franklin Resources Inc22,661$463.0K0.00%−17,490−43.6%Reduced
Virtu Financial LLC22,480$460.0K0.05%−978−4.2%Reduced
Oppenheimer & Co Inc22,125$452.0K0.01%+22,125New
Los Angeles Capital Management LLC22,061$451.0K0.00%−614−2.7%Reduced
Wedbush Securities Inc20,945$429.0K0.02%+505+2.5%Added
Envestnet Asset Management Inc20,025$410.0K0.00%+20,025New
Private Advisor Group, LLC19,487$399.0K0.00%+3,300+20.4%Added
Squarepoint Ops LLC19,295$395.0K0.00%−357,381−94.9%Reduced
Axxcess Wealth Management, LLC17,745$363.0K0.03%+17,745New
IHT Wealth Management, LLC17,700$362.0K0.03%+5,039+39.8%Added
Blair William & Co17,079$349.0K0.00%+3,970+30.3%Added
Graham Capital Management, L.P.16,475$337.0K0.02%−15,000−47.7%Reduced
Beacon Investment Advisory Services, Inc.15,813$324.0K0.01%+132+0.8%Added
Harbor Capital Advisors, Inc.15,596$319.0K0.12%+15,596New
Ameritas Investment Partners, Inc.14,908$305.0K0.01%00.0%Unchanged
Prudential Financial Inc14,722$301.0K0.00%−2,531−14.7%Reduced
Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors14,653$300.0K0.09%+150+1.0%Added
Advisor Group Holdings, Inc.14,522$299.0K0.00%+6,050+71.4%Added
Hamilton Lane Advisors LLC14,091$288.0K0.04%00.0%Unchanged
Simplex Trading, LLC13,497$276.0K0.01%−45,811−77.2%Reduced
Twin Lakes Capital Management, LLC13,341$273.0K0.15%00.0%Unchanged
STRS Ohio13,200$270.0K0.00%−7,400−35.9%Reduced
Engineers Gate Manager LP13,048$267.0K0.01%−11,619−47.1%Reduced
Ambassador Advisors, LLC13,000$266.0K0.05%−7,500−36.6%Reduced
Pluribus Labs, LLC12,130$248.0K0.26%+12,130New
Horizon Kinetics Asset Management LLC12,000$246.0K0.01%00.0%Unchanged
Dark Forest Capital Management LP11,536$236.0K0.09%+11,536New
Baird Financial Group, Inc.11,377$233.0K0.00%−135−1.2%Reduced
Titus Wealth Management11,261$230.0K0.10%+325+3.0%Added
V Wealth Advisors LLC11,102$227.0K0.03%+11,102New
Aigen Investment Management, LP10,145$219.0K0.01%+10,145New
Mackenzie Financial Corp10,631$218.0K0.00%−754−6.6%Reduced
Clearwater Capital Advisors, LLC10,394$213.0K0.02%+1,365+15.1%Added
Bank of Montreal10,085$212.0K0.00%+875+9.5%Added
Pathstone Family Office, LLC10,341$212.0K0.01%+1,406+15.7%Added
Great West Life Assurance Co10,331$210.0K0.00%+144+1.4%Added
ExodusPoint Capital Management, LP10,110$207.0K0.00%+10,110New
Cutler Group LP10,014$204.0K0.01%+10,014New
Walleye Capital LLC9,953$204.0K0.01%+9,953New
Shell Asset Management Co9,734$199.0K0.00%+39+0.4%Added
The PNC Financial Services Group, Inc.9,404$192.0K0.00%−182−1.9%Reduced
Tower Research Capital LLC (TRC)9,297$190.0K0.00%−5,866−38.7%Reduced
Essex Investment Management Co LLC9,058$185.0K0.02%+1,225+15.6%Added
Foundations Investment Advisors, LLC10,688$154.0K0.01%+10,688New
Twin Tree Management, LP7,412$152.0K0.00%+2,624+54.8%Added
Vienna Asset Management LLC7,366$151.0K0.14%+7,366New
Belpointe Asset Management LLC6,500$133.0K0.01%+866+15.4%Added
Manchester Capital Management LLC5,361$110.0K0.01%+5,021+1,476.8%Added
Covington Capital Management4,975$102.0K0.00%+4,975New
Smithfield Trust Co4,862$99.0K0.01%00.0%Unchanged