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Nautilus Biotechnology, Inc.

NAUT
Exchange
Nasdaq
Industry
Laboratory Analytical Instruments
SEC CIK
0001808805

No open-market purchases or sales by Nautilus Biotechnology, Inc. insiders were filed in the last 90 days; 93 institutions reported holding it in 13F filings for Q2 2026, worth $93.7M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Nautilus Biotechnology, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
81
+9 vs. Q3 2021
Shares held
59.6M
+18.6M (+45.4%) vs. Q3 2021
Total value
$234.8M
−$10.3M (−4.2%) vs. Q3 2021
New holders
22
24 more added
Sold out
13
13 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting NAUT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 81 institutions
Q1 2021: 0 institutionsQ2 2021: 56 institutionsQ3 2021: 72 institutionsQ4 2021: 81 institutionsQ1 2022: 82 institutionsQ2 2022: 83 institutionsQ3 2022: 86 institutionsQ4 2022: 81 institutionsQ1 2023: 73 institutionsQ2 2023: 75 institutionsQ3 2023: 75 institutionsQ4 2023: 76 institutionsQ1 2024: 73 institutionsQ2 2024: 77 institutionsQ3 2024: 83 institutionsQ4 2024: 88 institutionsQ1 2025: 88 institutionsQ2 2025: 71 institutionsQ3 2025: 68 institutionsQ4 2025: 68 institutionsQ1 2026: 81 institutionsQ2 2026: 93 institutions
Value heldQ4 2021: $234.8M
Q1 2021: $0Q2 2021: $379.7MQ3 2021: $245.1MQ4 2021: $234.8MQ1 2022: $243.5MQ2 2022: $154.7MQ3 2022: $119.7MQ4 2022: $82.9MQ1 2023: $123.3MQ2 2023: $173.4MQ3 2023: $142.5MQ4 2023: $189.6MQ1 2024: $185.9MQ2 2024: $149.8MQ3 2024: $182.9MQ4 2024: $107.3MQ1 2025: $54.0MQ2 2025: $43.3MQ3 2025: $48.9MQ4 2025: $113.7MQ1 2026: $210.8MQ2 2026: $93.7M
Institutions holding NAUT and their total value by quarter
QuarterHoldersValue
Q2 202693$93.7M
Q1 202681$210.8M
Q4 202568$113.7M
Q3 202568$48.9M
Q2 202571$43.3M
Q1 202588$54.0M
Q4 202488$107.3M
Q3 202483$182.9M
Q2 202477$149.8M
Q1 202473$185.9M
Q4 202376$189.6M
Q3 202375$142.5M
Q2 202375$173.4M
Q1 202373$123.3M
Q4 202281$82.9M
Q3 202286$119.7M
Q2 202283$154.7M
Q1 202282$243.5M
Q4 202181$234.8M
Q3 202172$245.1M
Q2 202156$379.7M
Q1 20210$0

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Nautilus Biotechnology, Inc.; share changes are against Q3 2021.

Institutions holding NAUT in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Perceptive Advisors LLC9,111,151$47.2M0.73%+200,000+2.2%Added
Madrona Venture Group, LLC6,020,770$31.2M5.89%00.0%Unchanged
AH Equity Partners Bio II, L.L.C.16,298,006$16.3M8.49%+16,298,006New
Ra Capital Management, L.P.2,436,430$12.6M0.22%00.0%Unchanged
Comprehensive Financial Management LLC2,224,619$11.5M0.15%00.0%Unchanged
Bain Capital Life Sciences Investors, LLC2,000,000$10.4M0.82%00.0%Unchanged
Amazon.com, Inc.1,457,055$7.55M0.04%00.0%Unchanged
OrbiMed Advisors LLC1,452,774$7.53M0.10%00.0%Unchanged
Botty Investors LLC1,449,551$7.51M2.23%+1,449,551New
Franklin Resources Inc1,424,982$7.38M0.00%−75,018−5.0%Reduced
Vanguard Group Inc1,285,297$6.66M0.00%+699,435+119.4%Added
BlackRock Inc.1,251,848$6.49M0.00%+23,560+1.9%Added
Tikvah Management LLC1,231,835$6.38M1.78%+523,295+73.9%Added
Ally Bridge Group (NY) LLC1,225,060$6.35M2.22%−274,940−18.3%Reduced
RTW Investments, LP1,100,000$5.70M0.08%00.0%Unchanged
Affinity Asset Advisors, LLC1,049,721$5.44M2.32%+74,721+7.7%Added
Nantahala Capital Management, LLC1,029,872$5.33M0.33%−14,395−1.4%Reduced
Sphera Funds Management Ltd.800,000$4.14M0.49%00.0%Unchanged
Rubric Capital Management LP747,607$3.87M0.18%00.0%Unchanged
Alyeska Investment Group, L.P.495,986$2.57M0.03%00.0%Unchanged
Geode Capital Management, LLC495,198$2.56M0.00%+109,327+28.3%Added
Clarius Group, LLC426,924$2.21M0.17%+408,663+2,237.9%Added
Board of Trustees of The Leland Stanford Junior University309,492$1.60M0.10%00.0%Unchanged
Bridger Management, LLC289,000$1.50M0.19%+163,000+129.4%Added
AH Equity Partners LSV II, L.L.C.1,355,911$1.36M0.73%+1,355,911New
Clearline Capital LP228,525$1.18M0.16%+69,395+43.6%Added
Hillman Co200,000$1.04M0.38%00.0%Unchanged
State Street Corp177,200$918.0K0.00%+19,500+12.4%Added
Susquehanna International Group, LLP158,252$820.0K0.00%−55,593−26.0%Reduced
Candriam Luxembourg S.C.A.155,000$803.0K0.01%00.0%Unchanged
Northern Trust Corp144,347$748.0K0.00%+53,763+59.4%Added
Pura Vida Investments, LLC143,798$745.0K0.08%−4,502−3.0%Reduced
Sender Co & Partners, Inc.143,335$742.0K0.47%+143,335New
Ensign Peak Advisors, Inc134,695$698.0K0.00%+134,695New
Skye Global Management LP110,000$570.0K0.01%+64,500+141.8%Added
Millennium Management LLC89,557$464.0K0.00%−198,092−68.9%Reduced
Simplex Trading, LLC80,731$418.0K0.01%+78,291+3,208.6%Added
Cubist Systematic Strategies, LLC69,934$362.0K0.00%−4,547−6.1%Reduced
Goldman Sachs Group Inc57,676$299.0K0.00%+47,253+453.4%Added
Lombard Odier Asset Management (USA) Corp50,000$259.0K0.04%00.0%Unchanged
Dowling & Yahnke LLC45,350$235.0K0.01%+45,350New
Vanguard Capital Wealth Advisors45,500$235.0K0.17%+45,500New
Morgan Stanley42,431$221.0K0.00%+11,675+38.0%Added
Marshall Wace, LLP37,713$195.0K0.00%−128,613−77.3%Reduced
Signaturefd, LLC37,313$193.0K0.01%+37,313New
Paloma Partners Management Co36,294$188.0K0.01%+14,503+66.6%Added
Aristides Capital LLC36,100$187.0K0.11%+36,100New
LMR Partners LLP27,248$141.0K0.00%+27,248New
Alpine Global Management, LLC26,477$137.0K0.02%00.0%Unchanged
Virtu Financial LLC25,495$132.0K0.01%+25,495New
Verition Fund Management LLC25,000$130.0K0.00%+10,000+66.7%Added
Qube Research & Technologies Ltd25,166$130.0K0.00%+10,138+67.5%Added
Charles Schwab Investment Management Inc22,256$116.0K0.00%00.0%Unchanged
Shay Capital LLC20,627$107.0K0.04%+20,627New
Bank of New York Mellon Corp20,096$104.0K0.00%00.0%Unchanged
Integrity Capital Management (HK) Ltd19,048$99.0K0.32%+19,048New
HSBC Holdings PLC18,464$96.0K0.00%+18,464New
ProShare Advisors LLC17,485$91.0K0.00%+17,485New
Citadel Advisors LLC15,638$81.0K0.00%−21,254−57.6%Reduced
Principal Financial Group Inc14,853$77.0K0.00%+14,853New
Mirabella Financial Services LLP14,437$75.0K0.01%+14,437New
Jane Street Group, LLC12,443$65.0K0.00%−516−4.0%Reduced
FNY Investment Advisers, LLC12,600$65.0K0.04%+12,600New
Stifel Financial Corp11,856$61.0K0.00%+1,045+9.7%Added
JPMorgan Chase & Co10,946$57.0K0.00%+10,946New
UBS Group AG5,631$30.0K0.00%−31,682−84.9%Reduced
Penserra Capital Management LLC5,859$30.0K0.00%+895+18.0%Added
Citigroup Inc4,510$23.0K0.00%+3,325+280.6%Added
Bank of America Corp4,153$22.0K0.00%−17,448−80.8%Reduced
American Portfolios Advisors3,440$17.8K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.3,000$16.0K0.00%+3,000New
Tower Research Capital LLC (TRC)2,570$14.0K0.00%+1,570+157.0%Added
Rockefeller Capital Management L.P.2,000$10.0K0.00%+1,000+100.0%Added
Advisor Group Holdings, Inc.1,280$7.00K0.00%00.0%Unchanged
TD Waterhouse Canada Inc.1,000$5.07K0.00%+1,000New
Wells Fargo & Company300$2.00K0.00%−312−51.0%Reduced
Eagle Bay Advisors LLC337$2.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.362$2.00K0.00%+362New
Your Advocates Ltd., LLP150$1.00K0.00%00.0%Unchanged
State of Wyoming198$1.00K0.00%+126+175.0%Added
Optimum Investment Advisors50$00.00%00.0%Unchanged
Federated Hermes, Inc.0$00.00%−800,000−100.0%Sold out
Boxer Capital, LLC0$00.00%−750,000−100.0%Sold out
Avidity Partners Management LP0$00.00%−600,000−100.0%Sold out
Suvretta Capital Management, LLC0$00.00%−314,835−100.0%Sold out
Casdin Capital, LLC0$00.00%−225,000−100.0%Sold out
Occudo Quantitative Strategies LP0$00.00%−85,148−100.0%Sold out
Belvedere Trading LLC0$00.00%−52,539−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−20,672−100.0%Sold out
Group One Trading, L.P.0$00.00%−20,252−100.0%Sold out
Raymond James & Associates0$00.00%−18,797−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−13,438−100.0%Sold out
Red Tortoise LLC0$00.00%−600−100.0%Sold out
Cutler Group LP0$00.00%−131−100.0%Sold out