Nautilus Biotechnology, Inc.
NAUT- Exchange
- Nasdaq
- Industry
- Laboratory Analytical Instruments
- SEC CIK
- 0001808805
No open-market purchases or sales by Nautilus Biotechnology, Inc. insiders were filed in the last 90 days; 93 institutions reported holding it in 13F filings for Q2 2026, worth $93.7M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Nautilus Biotechnology, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 68
- +4 vs. Q3 2025
- Shares held
- 58.3M
- +414.1K (+0.7%) vs. Q3 2025
- Total value
- $113.7M
- +$64.8M (+132.5%) vs. Q3 2025
- New holders
- 11
- 18 more added
- Sold out
- 7
- 15 more reduced
4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting NAUT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 93 | $93.7M |
| Q1 2026 | 81 | $210.8M |
| Q4 2025 | 68 | $113.7M |
| Q3 2025 | 68 | $48.9M |
| Q2 2025 | 71 | $43.3M |
| Q1 2025 | 88 | $54.0M |
| Q4 2024 | 88 | $107.3M |
| Q3 2024 | 83 | $182.9M |
| Q2 2024 | 77 | $149.8M |
| Q1 2024 | 73 | $185.9M |
| Q4 2023 | 76 | $189.6M |
| Q3 2023 | 75 | $142.5M |
| Q2 2023 | 75 | $173.4M |
| Q1 2023 | 73 | $123.3M |
| Q4 2022 | 81 | $82.9M |
| Q3 2022 | 86 | $119.7M |
| Q2 2022 | 83 | $154.7M |
| Q1 2022 | 82 | $243.5M |
| Q4 2021 | 81 | $234.8M |
| Q3 2021 | 72 | $245.1M |
| Q2 2021 | 56 | $379.7M |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Nautilus Biotechnology, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| AH Capital Management, L.L.C. | 17,653,917 | $34.4M | 2.18% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 12,594,211 | $24.6M | 0.45% | 00.0% | Unchanged |
| Cercano Management LLC | 7,172,985 | $14.0M | 0.53% | 00.0% | Unchanged |
| Madrona Venture Group, LLC | 6,020,770 | $11.7M | 53.24% | 00.0% | Unchanged |
| Vanguard Group Inc | 2,598,223 | $5.07M | 0.00% | +166,394+6.8% | Added |
| Comprehensive Financial Management LLC | 2,207,619 | $4.30M | 0.13% | 00.0% | Unchanged |
| Amazon.com, Inc. | 1,457,055 | $2.84M | 0.08% | 00.0% | Unchanged |
| Clarius Group, LLC | 1,209,646 | $2.36M | 0.13% | 00.0% | Unchanged |
| Millennium Management LLC | 1,019,996 | $1.99M | 0.00% | +52,448+5.4% | Added |
| Sentinel Trust Co Lba | 750,000 | $1.46M | 0.14% | +750,000 | New |
| Tikvah Management LLC | 726,895 | $1.42M | 0.38% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 611,984 | $1.19M | 0.00% | +368,711+151.6% | Added |
| Geode Capital Management, LLC | 560,909 | $1.09M | 0.00% | +7,307+1.3% | Added |
| Goldman Sachs Group Inc | 297,437 | $580.0K | 0.00% | +179,721+152.7% | Added |
| Dimensional Fund Advisors LP | 285,439 | $556.3K | 0.00% | −79,236−21.7% | Reduced |
| Renaissance Technologies LLC | 259,900 | $506.8K | 0.00% | −747,762−74.2% | Reduced |
| Alyeska Investment Group, L.P. | 253,468 | $494.3K | 0.00% | 00.0% | Unchanged |
| Jane Street Group, LLC | 206,837 | $403.3K | 0.00% | +58,649+39.6% | Added |
| State Street Corp | 201,255 | $392.4K | 0.00% | +22,500+12.6% | Added |
| Hillman Co | 200,000 | $390.0K | 0.14% | 00.0% | Unchanged |
| BlackRock, Inc. | 189,431 | $369.4K | 0.00% | −12,013−6.0% | Reduced |
| Crewe Advisors LLC | 136,052 | $265.3K | 0.02% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 130,000 | $253.5K | 0.01% | +5,000+4.0% | Added |
| Gsa Capital Partners LLP | 124,051 | $242.0K | 0.02% | −135,152−52.1% | Reduced |
| Qube Research & Technologies Ltd | 123,121 | $240.1K | 0.00% | +71,454+138.3% | Added |
| Marshall Wace, LLP | 117,059 | $228.3K | 0.00% | +117,059 | New |
| CI Private Wealth, LLC | 114,788 | $223.8K | 0.00% | −204,352−64.0% | Reduced |
| Northern Trust Corp | 107,011 | $208.7K | 0.00% | −10,825−9.2% | Reduced |
| Omers Administration Corp | 104,785 | $204.3K | 0.00% | +104,785 | New |
| Citigroup Inc | 61,712 | $120.3K | 0.00% | +60,828+6,881.0% | Added |
| Point72 Asset Management, L.P. | 60,833 | $118.6K | 0.00% | +60,833 | New |
| HSBC Holdings PLC | 49,449 | $97.9K | 0.00% | −149−0.3% | Reduced |
| Barclays PLC | 48,254 | $94.1K | 0.00% | 00.0% | Unchanged |
| Fayez Sarofim & Co | 45,000 | $87.8K | 0.00% | 00.0% | Unchanged |
| Ashton Thomas Private Wealth, LLC | 45,000 | $87.8K | 0.00% | 00.0% | Unchanged |
| CAPROCK Group, Inc. | 44,090 | $86.0K | 0.00% | +27,000+158.0% | Added |
| Susquehanna International Group, LLP | 42,916 | $83.7K | 0.00% | +42,916 | New |
| Palumbo Wealth Management LLC | 41,133 | $80.2K | 0.02% | −984−2.3% | Reduced |
| Lighthouse Investment Partners, LLC | 40,200 | $78.4K | 0.00% | +40,200 | New |
| Morgan Stanley | 38,584 | $75.2K | 0.00% | +12,856+50.0% | Added |
| Presidio Capital Management, LLC | 34,664 | $67.6K | 0.02% | 00.0% | Unchanged |
| Captrust Financial Advisors | 34,011 | $66.3K | 0.00% | +34,011 | New |
| XTX Topco Ltd | 33,608 | $65.5K | 0.00% | −12,116−26.5% | Reduced |
| Badgley Phelps Wealth Managers, LLC | 30,000 | $58.5K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 27,711 | $54.0K | 0.00% | +26,246+1,791.5% | Added |
| Callan Family Office, LLC | 25,970 | $50.6K | 0.00% | +11,140+75.1% | Added |
| Virtu Financial LLC | 23,532 | $46.0K | 0.00% | +3,849+19.6% | Added |
| Bank of America Corp | 20,167 | $39.3K | 0.00% | +19,354+2,380.6% | Added |
| Hudson Bay Capital Management LP | 19,062 | $37.2K | 0.00% | +19,062 | New |
| Garde Capital, Inc. | 18,000 | $35.1K | 0.00% | +18,000 | New |
| Two Sigma Securities, LLC | 16,239 | $31.7K | 0.00% | +16,239 | New |
| FNY Investment Advisers, LLC | 14,000 | $27.0K | 0.01% | 00.0% | Unchanged |
| Vanguard Capital Wealth Advisors | 13,000 | $25.4K | 0.02% | −500−3.7% | Reduced |
| Squarepoint Ops LLC | 11,316 | $22.1K | 0.00% | −120,511−91.4% | Reduced |
| UBS Group AG | 5,163 | $10.1K | 0.00% | +4,693+998.5% | Added |
| Rockefeller Capital Management L.P. | 5,000 | $9.75K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 3,880 | $7.57K | 0.00% | +3,880 | New |
| FMR LLC | 3,486 | $6.80K | 0.00% | −5,174−59.7% | Reduced |
| Royal Bank of Canada | 3,274 | $6.00K | 0.00% | +1,452+79.7% | Added |
| TD Waterhouse Canada Inc. | 1,000 | $1.93K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 715 | $1.39K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 560 | $1.09K | 0.00% | 00.0% | Unchanged |
| Your Advocates Ltd., LLP | 150 | $293 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 49 | $96 | 0.00% | −180−78.6% | Reduced |
| Optiver Holding B.V. | 40 | $78 | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 5 | $10 | 0.00% | −5,598−99.9% | Reduced |
| CWM, LLC | 55 | $0 | 0.00% | −127−69.8% | Reduced |
| Covestor Ltd | 8 | $0 | 0.00% | 00.0% | Unchanged |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −301,012−100.0% | Sold out |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −254,161−100.0% | Sold out |
| JPMorgan Chase & Co | 0 | $0 | 0.00% | −2,121−100.0% | Sold out |
| Aventura Private Wealth, LLC | 0 | $0 | 0.00% | −350−100.0% | Sold out |
| SRS Capital Advisors, Inc. | 0 | $0 | 0.00% | −148−100.0% | Sold out |
| True Wealth Design, LLC | 0 | $0 | 0.00% | −17−100.0% | Sold out |
| Cloud Capital Management, LLC | 0 | $0 | 0.00% | −49−100.0% | Sold out |
| Point72 Asia (Singapore) Pte. Ltd. | – | – | – | – | Not filed |
| Point72 (DIFC) Ltd | – | – | – | – | Not filed |
| Guerra Advisors Inc | – | – | – | – | Not filed |
| Cubist Systematic Strategies, LLC | – | – | – | – | Not filed |