Nautilus Biotechnology, Inc.
NAUT- Exchange
- Nasdaq
- Industry
- Laboratory Analytical Instruments
- SEC CIK
- 0001808805
No open-market purchases or sales by Nautilus Biotechnology, Inc. insiders were filed in the last 90 days; 93 institutions reported holding it in 13F filings for Q2 2026, worth $93.7M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Nautilus Biotechnology, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 68
- +4 vs. Q3 2025
- Shares held
- 58.3M
- +414.1K (+0.7%) vs. Q3 2025
- Total value
- $113.7M
- +$64.8M (+132.5%) vs. Q3 2025
- New holders
- 11
- 18 more added
- Sold out
- 7
- 15 more reduced
4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting NAUT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 93 | $93.7M |
| Q1 2026 | 81 | $210.8M |
| Q4 2025 | 68 | $113.7M |
| Q3 2025 | 68 | $48.9M |
| Q2 2025 | 71 | $43.3M |
| Q1 2025 | 88 | $54.0M |
| Q4 2024 | 88 | $107.3M |
| Q3 2024 | 83 | $182.9M |
| Q2 2024 | 77 | $149.8M |
| Q1 2024 | 73 | $185.9M |
| Q4 2023 | 76 | $189.6M |
| Q3 2023 | 75 | $142.5M |
| Q2 2023 | 75 | $173.4M |
| Q1 2023 | 73 | $123.3M |
| Q4 2022 | 81 | $82.9M |
| Q3 2022 | 86 | $119.7M |
| Q2 2022 | 83 | $154.7M |
| Q1 2022 | 82 | $243.5M |
| Q4 2021 | 81 | $234.8M |
| Q3 2021 | 72 | $245.1M |
| Q2 2021 | 56 | $379.7M |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Nautilus Biotechnology, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| CWM, LLC | 55 | $0 | 0.00% | −127−69.8% | Reduced |
| Covestor Ltd | 8 | $0 | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 5 | $10 | 0.00% | −5,598−99.9% | Reduced |
| Optiver Holding B.V. | 40 | $78 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 49 | $96 | 0.00% | −180−78.6% | Reduced |
| Your Advocates Ltd., LLP | 150 | $293 | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 560 | $1.09K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 715 | $1.39K | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 1,000 | $1.93K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 3,274 | $6.00K | 0.00% | +1,452+79.7% | Added |
| FMR LLC | 3,486 | $6.80K | 0.00% | −5,174−59.7% | Reduced |
| Group One Trading, L.P. | 3,880 | $7.57K | 0.00% | +3,880 | New |
| Rockefeller Capital Management L.P. | 5,000 | $9.75K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 5,163 | $10.1K | 0.00% | +4,693+998.5% | Added |
| Squarepoint Ops LLC | 11,316 | $22.1K | 0.00% | −120,511−91.4% | Reduced |
| Vanguard Capital Wealth Advisors | 13,000 | $25.4K | 0.02% | −500−3.7% | Reduced |
| FNY Investment Advisers, LLC | 14,000 | $27.0K | 0.01% | 00.0% | Unchanged |
| Two Sigma Securities, LLC | 16,239 | $31.7K | 0.00% | +16,239 | New |
| Garde Capital, Inc. | 18,000 | $35.1K | 0.00% | +18,000 | New |
| Hudson Bay Capital Management LP | 19,062 | $37.2K | 0.00% | +19,062 | New |
| Bank of America Corp | 20,167 | $39.3K | 0.00% | +19,354+2,380.6% | Added |
| Virtu Financial LLC | 23,532 | $46.0K | 0.00% | +3,849+19.6% | Added |
| Callan Family Office, LLC | 25,970 | $50.6K | 0.00% | +11,140+75.1% | Added |
| BNP Paribas Arbitrage, SA | 27,711 | $54.0K | 0.00% | +26,246+1,791.5% | Added |
| Badgley Phelps Wealth Managers, LLC | 30,000 | $58.5K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 33,608 | $65.5K | 0.00% | −12,116−26.5% | Reduced |
| Captrust Financial Advisors | 34,011 | $66.3K | 0.00% | +34,011 | New |
| Presidio Capital Management, LLC | 34,664 | $67.6K | 0.02% | 00.0% | Unchanged |
| Morgan Stanley | 38,584 | $75.2K | 0.00% | +12,856+50.0% | Added |
| Lighthouse Investment Partners, LLC | 40,200 | $78.4K | 0.00% | +40,200 | New |
| Palumbo Wealth Management LLC | 41,133 | $80.2K | 0.02% | −984−2.3% | Reduced |
| Susquehanna International Group, LLP | 42,916 | $83.7K | 0.00% | +42,916 | New |
| CAPROCK Group, Inc. | 44,090 | $86.0K | 0.00% | +27,000+158.0% | Added |
| Fayez Sarofim & Co | 45,000 | $87.8K | 0.00% | 00.0% | Unchanged |
| Ashton Thomas Private Wealth, LLC | 45,000 | $87.8K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 48,254 | $94.1K | 0.00% | 00.0% | Unchanged |
| HSBC Holdings PLC | 49,449 | $97.9K | 0.00% | −149−0.3% | Reduced |
| Point72 Asset Management, L.P. | 60,833 | $118.6K | 0.00% | +60,833 | New |
| Citigroup Inc | 61,712 | $120.3K | 0.00% | +60,828+6,881.0% | Added |
| Omers Administration Corp | 104,785 | $204.3K | 0.00% | +104,785 | New |
| Northern Trust Corp | 107,011 | $208.7K | 0.00% | −10,825−9.2% | Reduced |
| CI Private Wealth, LLC | 114,788 | $223.8K | 0.00% | −204,352−64.0% | Reduced |
| Marshall Wace, LLP | 117,059 | $228.3K | 0.00% | +117,059 | New |
| Qube Research & Technologies Ltd | 123,121 | $240.1K | 0.00% | +71,454+138.3% | Added |
| Gsa Capital Partners LLP | 124,051 | $242.0K | 0.02% | −135,152−52.1% | Reduced |
| Bridgeway Capital Management, LLC | 130,000 | $253.5K | 0.01% | +5,000+4.0% | Added |
| Crewe Advisors LLC | 136,052 | $265.3K | 0.02% | 00.0% | Unchanged |
| BlackRock, Inc. | 189,431 | $369.4K | 0.00% | −12,013−6.0% | Reduced |
| Hillman Co | 200,000 | $390.0K | 0.14% | 00.0% | Unchanged |
| State Street Corp | 201,255 | $392.4K | 0.00% | +22,500+12.6% | Added |
| Jane Street Group, LLC | 206,837 | $403.3K | 0.00% | +58,649+39.6% | Added |
| Alyeska Investment Group, L.P. | 253,468 | $494.3K | 0.00% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 259,900 | $506.8K | 0.00% | −747,762−74.2% | Reduced |
| Dimensional Fund Advisors LP | 285,439 | $556.3K | 0.00% | −79,236−21.7% | Reduced |
| Goldman Sachs Group Inc | 297,437 | $580.0K | 0.00% | +179,721+152.7% | Added |
| Geode Capital Management, LLC | 560,909 | $1.09M | 0.00% | +7,307+1.3% | Added |
| Acadian Asset Management LLC | 611,984 | $1.19M | 0.00% | +368,711+151.6% | Added |
| Tikvah Management LLC | 726,895 | $1.42M | 0.38% | 00.0% | Unchanged |
| Sentinel Trust Co Lba | 750,000 | $1.46M | 0.14% | +750,000 | New |
| Millennium Management LLC | 1,019,996 | $1.99M | 0.00% | +52,448+5.4% | Added |
| Clarius Group, LLC | 1,209,646 | $2.36M | 0.13% | 00.0% | Unchanged |
| Amazon.com, Inc. | 1,457,055 | $2.84M | 0.08% | 00.0% | Unchanged |
| Comprehensive Financial Management LLC | 2,207,619 | $4.30M | 0.13% | 00.0% | Unchanged |
| Vanguard Group Inc | 2,598,223 | $5.07M | 0.00% | +166,394+6.8% | Added |
| Madrona Venture Group, LLC | 6,020,770 | $11.7M | 53.24% | 00.0% | Unchanged |
| Cercano Management LLC | 7,172,985 | $14.0M | 0.53% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 12,594,211 | $24.6M | 0.45% | 00.0% | Unchanged |
| AH Capital Management, L.L.C. | 17,653,917 | $34.4M | 2.18% | 00.0% | Unchanged |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −301,012−100.0% | Sold out |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −254,161−100.0% | Sold out |
| JPMorgan Chase & Co | 0 | $0 | 0.00% | −2,121−100.0% | Sold out |
| Aventura Private Wealth, LLC | 0 | $0 | 0.00% | −350−100.0% | Sold out |
| SRS Capital Advisors, Inc. | 0 | $0 | 0.00% | −148−100.0% | Sold out |
| True Wealth Design, LLC | 0 | $0 | 0.00% | −17−100.0% | Sold out |
| Cloud Capital Management, LLC | 0 | $0 | 0.00% | −49−100.0% | Sold out |
| Point72 Asia (Singapore) Pte. Ltd. | – | – | – | – | Not filed |
| Point72 (DIFC) Ltd | – | – | – | – | Not filed |
| Guerra Advisors Inc | – | – | – | – | Not filed |
| Cubist Systematic Strategies, LLC | – | – | – | – | Not filed |