Mineralys Therapeutics, Inc.
MLYS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001933414
In the last 90 days, Mineralys Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 225 institutions reported holding it in 13F filings for Q2 2026, worth $2.69B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Mineralys Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 223
- +32 vs. Q3 2025
- Shares held
- 88.4M
- +9.06M (+11.4%) vs. Q3 2025
- Total value
- $3.21B
- +$199.8M (+6.6%) vs. Q3 2025
- New holders
- 52
- 82 more added
- Sold out
- 20
- 72 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MLYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 225 | $2.69B |
| Q1 2026 | 215 | $2.46B |
| Q4 2025 | 223 | $3.21B |
| Q3 2025 | 193 | $3.01B |
| Q2 2025 | 166 | $888.8M |
| Q1 2025 | 149 | $966.2M |
| Q4 2024 | 109 | $572.2M |
| Q3 2024 | 106 | $540.1M |
| Q2 2024 | 94 | $516.6M |
| Q1 2024 | 92 | $540.6M |
| Q4 2023 | 87 | $298.5M |
| Q3 2023 | 77 | $252.1M |
| Q2 2023 | 68 | $429.2M |
| Q1 2023 | 68 | $385.4M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Mineralys Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sectoral Asset Management Inc | 31,625 | $1.15M | 0.92% | −2,260−6.7% | Reduced |
| Victory Capital Management Inc | 32,881 | $1.19M | 0.00% | +27,174+476.2% | Added |
| HRT Financial LP | 37,236 | $1.35M | 0.00% | −96,802−72.2% | Reduced |
| Deutsche Bank AG | 37,245 | $1.35M | 0.00% | +6,315+20.4% | Added |
| DAFNA Capital Management LLC | 38,490 | $1.40M | 0.32% | −45,000−53.9% | Reduced |
| Tudor Investment Corp Et Al | 39,046 | $1.42M | 0.01% | +39,046 | New |
| Seven Fleet Capital Management LP | 42,025 | $1.53M | 1.03% | +42,025 | New |
| California State Teachers Retirement System | 43,348 | $1.57M | 0.00% | +6,749+18.4% | Added |
| Legal & General Group Plc | 43,938 | $1.59M | 0.00% | −1,491−3.3% | Reduced |
| Erste Asset Management GmbH | 45,000 | $1.66M | 0.01% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 46,246 | $1.68M | 0.00% | −50,901−52.4% | Reduced |
| JPMorgan Chase & Co | 46,683 | $1.69M | 0.00% | −136,997−74.6% | Reduced |
| Profund Advisors LLC | 47,024 | $1.71M | 0.05% | +39,768+548.1% | Added |
| J. Goldman & Co LP | 47,288 | $1.72M | 0.07% | +3,420+7.8% | Added |
| Algert Global LLC | 47,500 | $1.72M | 0.03% | 00.0% | Unchanged |
| PFM Health Sciences, LP | 47,637 | $1.73M | 0.18% | +47,637 | New |
| Schonfeld Strategic Advisors LLC | 49,821 | $1.81M | 0.01% | +35,203+240.8% | Added |
| State of Wisconsin Investment Board | 49,941 | $1.81M | 0.00% | +23,015+85.5% | Added |
| Findell Capital Management LLC | 50,000 | $1.81M | 0.60% | −200,000−80.0% | Reduced |
| Rhumbline Advisers | 54,284 | $1.97M | 0.00% | −1,007−1.8% | Reduced |
| Wells Fargo & Company | 56,756 | $2.06M | 0.00% | +26,702+88.8% | Added |
| Zimmer Partners, LP | 57,500 | $2.09M | 0.05% | −42,500−42.5% | Reduced |
| Moore Capital Management, LP | 60,000 | $2.18M | 0.04% | −105,000−63.6% | Reduced |
| AQR Capital Management LLC | 62,300 | $2.26M | 0.00% | +44,178+243.8% | Added |
| Winton Group Ltd | 64,806 | $2.35M | 0.08% | +64,806 | New |
| Alps Advisors Inc | 64,987 | $2.36M | 0.01% | +64,987 | New |
| Blue Owl Capital Holdings LP | 65,944 | $2.39M | 0.74% | −35,000−34.7% | Reduced |
| Greenland Capital Management LP | 69,000 | $2.50M | 0.36% | −36,853−34.8% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 69,362 | $2.52M | 0.09% | +16,514+31.2% | Added |
| XTX Topco Ltd | 73,678 | $2.67M | 0.07% | +54,838+291.1% | Added |
| UBS Asset Management Americas Inc | 75,897 | $2.75M | 0.00% | +16,855+28.5% | Added |
| Susquehanna Portfolio Strategies, LLC | 78,092 | $2.83M | 0.04% | 00.0% | Unchanged |
| Millennium Management LLC | 78,625 | $2.85M | 0.00% | −325,964−80.6% | Reduced |
| Verition Fund Management LLC | 83,840 | $3.04M | 0.02% | +65,377+354.1% | Added |
| Prudential Financial Inc | 89,065 | $3.23M | 0.00% | +38,640+76.6% | Added |
| Swiss National Bank | 90,100 | $3.27M | 0.00% | +1,600+1.8% | Added |
| Silverarc Capital Management, LLC | 94,983 | $3.45M | 0.50% | +14,983+18.7% | Added |
| EAM Investors, LLC | 96,135 | $3.49M | 0.39% | −31,412−24.6% | Reduced |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 111,753 | $4.06M | 0.00% | +111,753 | New |
| Ensign Peak Advisors, Inc | 112,190 | $4.07M | 0.01% | +4,550+4.2% | Added |
| Voya Investment Management LLC | 112,672 | $4.09M | 0.00% | −25,854−18.7% | Reduced |
| Trexquant Investment LP | 112,788 | $4.09M | 0.04% | +68,815+156.5% | Added |
| Nantahala Capital Management, LLC | 113,285 | $4.11M | 0.25% | −45,428−28.6% | Reduced |
| Simplify Asset Management Inc. | 114,182 | $4.14M | 0.07% | −104,544−47.8% | Reduced |
| Nuveen, LLC | 122,947 | $4.46M | 0.00% | +36,031+41.5% | Added |
| HighVista Strategies LLC | 124,544 | $4.52M | 1.16% | −85,285−40.6% | Reduced |
| Schroder Investment Management Group | 130,592 | $4.64M | 0.00% | +130,592 | New |
| Rafferty Asset Management, LLC | 127,917 | $4.64M | 0.02% | +96,232+303.7% | Added |
| Bank of New York Mellon Corp | 131,839 | $4.78M | 0.00% | +18,042+15.9% | Added |
| ADAR1 Capital Management, LLC | 136,231 | $4.94M | 0.37% | +57,993+74.1% | Added |
| Brevan Howard Capital Management LP | 139,293 | $4.98M | 0.10% | +139,293 | New |
| Dimensional Fund Advisors LP | 137,636 | $4.99M | 0.00% | −9,142−6.2% | Reduced |
| Artia Global Partners LP | 137,800 | $5.00M | 0.80% | +81,200+143.5% | Added |
| Rhenman & Partners Asset Management AB | 142,571 | $5.17M | 0.48% | −22,429−13.6% | Reduced |
| Susquehanna International Group, LLP | 143,208 | $5.20M | 0.01% | +85,985+150.3% | Added |
| Burkehill Global Management, LP | 150,000 | $5.44M | 0.36% | 00.0% | Unchanged |
| Velan Capital Investment Management LP | 151,000 | $5.48M | 3.19% | −24,600−14.0% | Reduced |
| BNP Paribas Arbitrage, SA | 172,929 | $6.28M | 0.00% | −453,219−72.4% | Reduced |
| Buckley Capital Advisors, LLC | 174,300 | $6.33M | 5.50% | +174,300 | New |
| Russell Investments Group, Ltd. | 175,361 | $6.36M | 0.01% | +172,097+5,272.6% | Added |
| Ikarian Capital, LLC | 200,000 | $7.26M | 0.94% | +200,000 | New |
| UBS Group AG | 201,280 | $7.30M | 0.00% | +111,776+124.9% | Added |
| Davern Capital Partners, LP | 210,648 | $7.64M | 2.47% | +210,648 | New |
| Swedbank AB | 221,400 | $8.03M | 0.01% | −77,900−26.0% | Reduced |
| Barclays PLC | 223,283 | $8.10M | 0.00% | −430,547−65.8% | Reduced |
| SG Americas Securities, LLC | 230,795 | $8.38M | 0.01% | +130,758+130.7% | Added |
| Squarepoint Ops LLC | 246,804 | $8.96M | 0.02% | +203,791+473.8% | Added |
| Marshall Wace, LLP | 249,130 | $9.04M | 0.01% | +249,130 | New |
| Iron Triangle Partners LP | 257,085 | $9.33M | 1.07% | +257,085 | New |
| StemPoint Capital LP | 290,049 | $10.5M | 1.81% | +131,937+83.4% | Added |
| Northern Trust Corp | 299,863 | $10.9M | 0.00% | −90,944−23.3% | Reduced |
| Lord, Abbett & Co. LLC | 312,396 | $11.3M | 0.03% | +312,396 | New |
| Renaissance Technologies LLC | 322,100 | $11.7M | 0.02% | +274,700+579.5% | Added |
| Catalio Capital Management, LP | 331,849 | $12.0M | 2.13% | +331,849 | New |
| Two Sigma Advisers, LP | 353,700 | $12.8M | 0.02% | +353,700 | New |
| 22NW, LP | 358,325 | $13.0M | 10.02% | 00.0% | Unchanged |
| TimesSquare Capital Management, LLC | 380,100 | $13.8M | 0.21% | +380,100 | New |
| Citadel Advisors LLC | 399,919 | $14.5M | 0.01% | −1,667,308−80.7% | Reduced |
| Parkman Healthcare Partners LLC | 410,249 | $14.9M | 1.42% | −45,274−9.9% | Reduced |
| Rock Springs Capital Management LP | 427,596 | $15.5M | 0.80% | +19,283+4.7% | Added |
| Sphera Funds Management Ltd. | 449,003 | $16.3M | 3.41% | +229,093+104.2% | Added |
| Charles Schwab Investment Management Inc | 461,300 | $16.7M | 0.00% | +52,113+12.7% | Added |
| Qube Research & Technologies Ltd | 496,549 | $18.0M | 0.03% | +316,123+175.2% | Added |
| Two Sigma Investments, LP | 610,403 | $22.2M | 0.03% | +610,403 | New |
| Morgan Stanley | 639,507 | $23.2M | 0.00% | −737,491−53.6% | Reduced |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 659,076 | $23.9M | 2.12% | +659,076 | New |
| Armistice Capital, LLC | 676,035 | $24.5M | 0.60% | +168,385+33.2% | Added |
| Candriam Luxembourg S.C.A. | 678,387 | $24.6M | 0.12% | +110,606+19.5% | Added |
| Siren, L.L.C. | 699,999 | $25.4M | 0.76% | +699,999 | New |
| Affinity Asset Advisors, LLC | 730,000 | $26.5M | 1.90% | −20,000−2.7% | Reduced |
| Integral Health Asset Management, LLC | 750,000 | $27.2M | 1.38% | −750,000−50.0% | Reduced |
| Wellington Management Group LLP | 784,267 | $28.5M | 0.00% | +822+0.1% | Added |
| Farallon Capital Management, L.L.C. | 823,296 | $29.9M | 0.16% | −849,757−50.8% | Reduced |
| Pictet Asset Management Holding SA | 852,883 | $31.0M | 0.03% | −76,286−8.2% | Reduced |
| American Century Companies Inc | 908,093 | $33.0M | 0.02% | +28,411+3.2% | Added |
| Alliancebernstein L.P. | 922,516 | $33.5M | 0.01% | +40,101+4.5% | Added |
| OrbiMed Advisors LLC | 980,400 | $35.6M | 0.73% | −489,094−33.3% | Reduced |
| Bank of America Corp | 987,280 | $35.8M | 0.00% | +219,015+28.5% | Added |
| Boothbay Fund Management, LLC | 992,082 | $36.0M | 0.95% | +49,456+5.2% | Added |
| D. E. Shaw & Co., Inc. | 1,150,670 | $41.8M | 0.03% | +539,747+88.3% | Added |