Mineralys Therapeutics, Inc.
MLYS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001933414
In the last 90 days, Mineralys Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 225 institutions reported holding it in 13F filings for Q2 2026, worth $2.69B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Mineralys Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 193
- +27 vs. Q2 2025
- Shares held
- 79.3M
- +13.6M (+20.8%) vs. Q2 2025
- Total value
- $3.01B
- +$2.12B (+238.4%) vs. Q2 2025
- New holders
- 42
- 69 more added
- Sold out
- 15
- 63 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MLYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 225 | $2.69B |
| Q1 2026 | 215 | $2.46B |
| Q4 2025 | 223 | $3.21B |
| Q3 2025 | 193 | $3.01B |
| Q2 2025 | 166 | $888.8M |
| Q1 2025 | 149 | $966.2M |
| Q4 2024 | 109 | $572.2M |
| Q3 2024 | 106 | $540.1M |
| Q2 2024 | 94 | $516.6M |
| Q1 2024 | 92 | $540.6M |
| Q4 2023 | 87 | $298.5M |
| Q3 2023 | 77 | $252.1M |
| Q2 2023 | 68 | $429.2M |
| Q1 2023 | 68 | $385.4M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Mineralys Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Legal & General Group Plc | 45,429 | $1.72M | 0.00% | +9,380+26.0% | Added |
| Erste Asset Management GmbH | 45,000 | $1.77M | 0.02% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 47,400 | $1.80M | 0.00% | −129,526−73.2% | Reduced |
| Algert Global LLC | 47,500 | $1.80M | 0.03% | +47,500 | New |
| Prudential Financial Inc | 50,425 | $1.91M | 0.00% | −301,800−85.7% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 52,848 | $2.00M | 0.07% | +21,753+70.0% | Added |
| Rhumbline Advisers | 55,291 | $2.10M | 0.00% | +1,695+3.2% | Added |
| Artia Global Partners LP | 56,600 | $2.15M | 0.38% | +15,500+37.7% | Added |
| Susquehanna International Group, LLP | 57,223 | $2.17M | 0.00% | +1,137+2.0% | Added |
| UBS Asset Management Americas Inc | 59,042 | $2.24M | 0.00% | +34,638+141.9% | Added |
| Cinctive Capital Management LP | 71,713 | $2.72M | 0.14% | +55,600+345.1% | Added |
| Hudson Bay Capital Management LP | 75,768 | $2.87M | 0.02% | +75,768 | New |
| Susquehanna Portfolio Strategies, LLC | 78,092 | $2.96M | 0.05% | −83,042−51.5% | Reduced |
| ADAR1 Capital Management, LLC | 78,238 | $2.97M | 0.29% | −223,887−74.1% | Reduced |
| Silverarc Capital Management, LLC | 80,000 | $3.03M | 0.44% | −35,282−30.6% | Reduced |
| DAFNA Capital Management LLC | 83,490 | $3.17M | 0.78% | −288,033−77.5% | Reduced |
| Nuveen, LLC | 86,916 | $3.30M | 0.00% | +9,269+11.9% | Added |
| Swiss National Bank | 88,500 | $3.36M | 0.00% | +26,600+43.0% | Added |
| UBS Group AG | 89,504 | $3.39M | 0.00% | −25,635−22.3% | Reduced |
| Ameriprise Financial Inc | 97,147 | $3.68M | 0.00% | +46,290+91.0% | Added |
| Zimmer Partners, LP | 100,000 | $3.79M | 0.09% | −62,733−38.5% | Reduced |
| SG Americas Securities, LLC | 100,037 | $3.79M | 0.01% | −23,950−19.3% | Reduced |
| Blue Owl Capital Holdings LP | 100,944 | $3.83M | 1.19% | −235,000−70.0% | Reduced |
| Adage Capital Partners GP, L.L.C. | 105,000 | $3.98M | 0.01% | +105,000 | New |
| Greenland Capital Management LP | 105,853 | $4.01M | 0.59% | +95,853+958.5% | Added |
| Ensign Peak Advisors, Inc | 107,640 | $4.08M | 0.01% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 113,797 | $4.32M | 0.00% | +17,382+18.0% | Added |
| Jain Global LLC | 120,854 | $4.58M | 0.06% | +120,854 | New |
| EAM Investors, LLC | 127,547 | $4.76M | 0.55% | +127,547 | New |
| HRT Financial LP | 134,038 | $5.08M | 0.02% | +123,961+1,230.1% | Added |
| Voya Investment Management LLC | 138,526 | $5.25M | 0.01% | +88,050+174.4% | Added |
| Dimensional Fund Advisors LP | 146,778 | $5.57M | 0.00% | −40,606−21.7% | Reduced |
| Burkehill Global Management, LP | 150,000 | $5.69M | 0.32% | +150,000 | New |
| StemPoint Capital LP | 158,112 | $6.00M | 1.21% | −473,474−75.0% | Reduced |
| Nantahala Capital Management, LLC | 158,713 | $6.02M | 0.37% | −195,269−55.2% | Reduced |
| Citigroup Inc | 163,168 | $6.19M | 0.00% | +136,050+501.7% | Added |
| Moore Capital Management, LP | 165,000 | $6.26M | 0.12% | +165,000 | New |
| Rhenman & Partners Asset Management AB | 165,000 | $6.26M | 0.69% | +165,000 | New |
| Atika Capital Management LLC | 174,000 | $6.60M | 0.56% | +174,000 | New |
| Velan Capital Investment Management LP | 175,600 | $6.66M | 6.25% | +1,000+0.6% | Added |
| Qube Research & Technologies Ltd | 180,426 | $6.84M | 0.01% | −170,687−48.6% | Reduced |
| JPMorgan Chase & Co | 183,680 | $6.97M | 0.00% | +158,180+620.3% | Added |
| Invesco Ltd. | 187,986 | $7.13M | 0.00% | +162,243+630.2% | Added |
| Tang Capital Management LLC | 200,000 | $7.58M | 0.29% | 00.0% | Unchanged |
| HighVista Strategies LLC | 209,829 | $7.96M | 1.95% | +59,691+39.8% | Added |
| Simplify Asset Management Inc. | 218,726 | $8.29M | 0.17% | +218,726 | New |
| Sphera Funds Management Ltd. | 219,910 | $8.34M | 1.98% | −261,064−54.3% | Reduced |
| Findell Capital Management LLC | 250,000 | $9.48M | 4.33% | +250,000 | New |
| Swedbank AB | 299,300 | $11.3M | 0.01% | −84,500−22.0% | Reduced |
| 22NW, LP | 358,325 | $13.6M | 7.07% | −201,717−36.0% | Reduced |
| Jennison Associates LLC | 376,346 | $14.3M | 0.01% | −858,976−69.5% | Reduced |
| Northern Trust Corp | 390,807 | $14.8M | 0.00% | +51,782+15.3% | Added |
| Millennium Management LLC | 404,589 | $15.3M | 0.01% | +161,020+66.1% | Added |
| Rock Springs Capital Management LP | 408,313 | $15.5M | 0.91% | +83,800+25.8% | Added |
| Charles Schwab Investment Management Inc | 409,187 | $15.5M | 0.00% | +84,982+26.2% | Added |
| Nearwater Capital Markets, Ltd | 450,000 | $17.1M | 0.23% | +450,000 | New |
| Parkman Healthcare Partners LLC | 455,523 | $17.3M | 1.90% | −8,078−1.7% | Reduced |
| Armistice Capital, LLC | 507,650 | $19.3M | 0.60% | +329,650+185.2% | Added |
| Pale Fire Capital SE | 532,407 | $20.2M | 2.21% | +85,781+19.2% | Added |
| Candriam Luxembourg S.C.A. | 567,781 | $21.5M | 0.11% | −256,406−31.1% | Reduced |
| D. E. Shaw & Co., Inc. | 610,923 | $23.2M | 0.02% | +36,716+6.4% | Added |
| BNP Paribas Arbitrage, SA | 626,148 | $23.7M | 0.02% | +622,040+15,142.2% | Added |
| Barclays PLC | 653,830 | $24.8M | 0.01% | +509,946+354.4% | Added |
| Goldman Sachs Group Inc | 711,661 | $27.0M | 0.00% | +84,874+13.5% | Added |
| Affinity Asset Advisors, LLC | 750,000 | $28.4M | 2.65% | −150,000−16.7% | Reduced |
| Bank of America Corp | 768,265 | $29.1M | 0.00% | +504,909+191.7% | Added |
| Wellington Management Group LLP | 783,445 | $29.7M | 0.01% | +667,997+578.6% | Added |
| American Century Companies Inc | 879,682 | $33.4M | 0.02% | +44,901+5.4% | Added |
| Alliancebernstein L.P. | 882,415 | $33.5M | 0.01% | +855,348+3,160.1% | Added |
| Pictet Asset Management Holding SA | 929,169 | $35.2M | 0.03% | −338,824−26.7% | Reduced |
| Boothbay Fund Management, LLC | 942,626 | $35.7M | 0.92% | +125,700+15.4% | Added |
| Polar Capital Holdings Plc | 1,058,776 | $40.1M | 0.19% | +1,058,776 | New |
| Geode Capital Management, LLC | 1,123,411 | $42.6M | 0.00% | +168,851+17.7% | Added |
| Holocene Advisors, LP | 1,205,377 | $45.7M | 0.11% | +1,205,377 | New |
| State Street Corp | 1,303,023 | $49.4M | 0.00% | −140,536−9.7% | Reduced |
| Morgan Stanley | 1,376,998 | $52.2M | 0.00% | +789,168+134.3% | Added |
| OrbiMed Advisors LLC | 1,469,494 | $55.7M | 1.34% | +709,143+93.3% | Added |
| Integral Health Asset Management, LLC | 1,500,000 | $56.9M | 4.15% | −1,200,000−44.4% | Reduced |
| Farallon Capital Management, L.L.C. | 1,673,053 | $63.4M | 0.36% | +1,673,053 | New |
| Laurion Capital Management LP | 1,720,445 | $65.2M | 8.90% | −42,137−2.4% | Reduced |
| Point72 Asset Management, L.P. | 1,799,628 | $68.2M | 0.15% | +1,799,628 | New |
| Franklin Resources Inc | 1,809,768 | $68.6M | 0.02% | +6,171+0.3% | Added |
| Citadel Advisors LLC | 2,067,227 | $78.4M | 0.06% | +2,052,845+14,273.7% | Added |
| FMR LLC | 2,071,255 | $78.5M | 0.00% | +1,766,369+579.4% | Added |
| Sr One Capital Management, LP | 2,113,933 | $80.2M | 11.59% | −1,014,000−32.4% | Reduced |
| Suvretta Capital Management, LLC | 2,132,133 | $80.9M | 2.45% | +387,641+22.2% | Added |
| Capital International Investors | 2,393,396 | $90.8M | 0.01% | −505,624−17.4% | Reduced |
| Caligan Partners LP | 2,772,654 | $105.1M | 14.59% | +755,302+37.4% | Added |
| Vanguard Group Inc | 3,018,999 | $114.5M | 0.00% | +692,550+29.8% | Added |
| BlackRock, Inc. | 3,671,614 | $139.2M | 0.00% | +573,854+18.5% | Added |
| Samsara BioCapital, LLC | 6,263,151 | $237.5M | 31.01% | +588,235+10.4% | Added |
| Ra Capital Management, L.P. | 7,323,750 | $277.7M | 3.42% | +1,176,470+19.1% | Added |
| Catalys Pacific, LLC | 8,903,838 | $337.6M | 96.09% | 00.0% | Unchanged |
| Dark Forest Capital Management LP | 0 | $0 | 0.00% | −126,726−100.0% | Sold out |
| Woodline Partners LP | 0 | $0 | 0.00% | −87,868−100.0% | Sold out |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −79,723−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −73,921−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −48,401−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −21,852−100.0% | Sold out |
| Intech Investment Management LLC | 0 | $0 | 0.00% | −21,629−100.0% | Sold out |