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MBX Biosciences, Inc.

MBX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001776111

In the last 90 days, MBX Biosciences, Inc. insiders filed 0 open-market purchases and 1 sale; 172 institutions reported holding it in 13F filings for Q2 2026, worth $3.06B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in MBX Biosciences, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
118
+30 vs. Q2 2025
Shares held
47.8M
+11.0M (+29.7%) vs. Q2 2025
Total value
$836.4M
+$416.0M (+99.0%) vs. Q2 2025
New holders
39
29 more added
Sold out
9
30 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MBX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 118 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 45 institutionsQ4 2024: 63 institutionsQ1 2025: 79 institutionsQ2 2025: 88 institutionsQ3 2025: 118 institutionsQ4 2025: 138 institutionsQ1 2026: 157 institutionsQ2 2026: 172 institutions
Value heldQ3 2025: $836.4M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $784.1MQ4 2024: $606.5MQ1 2025: $263.2MQ2 2025: $420.3MQ3 2025: $836.4MQ4 2025: $1.53BQ1 2026: $1.57BQ2 2026: $3.06B
Institutions holding MBX and their total value by quarter
QuarterHoldersValue
Q2 2026172$3.06B
Q1 2026157$1.57B
Q4 2025138$1.53B
Q3 2025118$836.4M
Q2 202588$420.3M
Q1 202579$263.2M
Q4 202463$606.5M
Q3 202445$784.1M
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding MBX Biosciences, Inc.; share changes are against Q2 2025.

Institutions holding MBX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Essential Partners LLC2$350.00%00.0%Unchanged
Rothschild Investment LLC20$3500.00%00.0%Unchanged
EverSource Wealth Advisors, LLC23$4030.00%−6−20.7%Reduced
Allworth Financial LP25$4380.00%00.0%Unchanged
Parallel Advisors, LLC61$1.07K0.00%−47−43.5%Reduced
Rise Advisors, LLC68$1.19K0.00%00.0%Unchanged
Comerica Bank76$1.33K0.00%+76New
Washington Trust Advisors, Inc.83$1.45K0.00%+83New
UMA Financial Services, Inc.109$1.91K0.00%00.0%Unchanged
Citigroup Inc178$3.12K0.00%−5,545−96.9%Reduced
Signaturefd, LLC179$3.13K0.00%+78+77.2%Added
The PNC Financial Services Group, Inc.252$4.41K0.00%+252New
GAMMA Investing LLC299$5.23K0.00%00.0%Unchanged
Farther Finance Advisors, LLC328$5.74K0.00%+328New
US Bancorp337$5.90K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.398$6.96K0.00%+398New
Amalgamated Bank384$7.00K0.00%00.0%Unchanged
STRS Ohio700$12.3K0.00%00.0%Unchanged
Royal Bank of Canada960$17.0K0.00%−338−26.0%Reduced
Sterling Capital Management LLC1,058$18.5K0.00%+598+130.0%Added
California State Teachers Retirement System1,065$18.6K0.00%+1+0.1%Added
Ameritas Investment Partners, Inc.1,177$20.6K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,267$22.2K0.00%−843−40.0%Reduced
Legal & General Group Plc1,328$23.2K0.00%−223−14.4%Reduced
CWM, LLC1,384$24.0K0.00%−418−23.2%Reduced
Russell Investments Group, Ltd.1,481$25.9K0.00%+1,446+4,131.4%Added
FNY Investment Advisers, LLC1,575$27.0K0.01%+1,575New
Nisa Investment Advisors, LLC1,592$27.9K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA2,896$50.7K0.00%+1,567+117.9%Added
Rockefeller Capital Management L.P.3,000$52.5K0.00%−31,135−91.2%Reduced
New York State Common Retirement Fund4,300$75.3K0.00%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey4,509$78.9K0.00%+2,366+110.4%Added
Acadian Asset Management LLC5,009$86.0K0.00%+5,009New
China Universal Asset Management Co., Ltd.5,000$87.5K0.01%+5,000New
JPMorgan Chase & Co6,175$108.1K0.00%−2,009−24.5%Reduced
Quarry LP6,499$113.7K0.03%−1,501−18.8%Reduced
Mirae Asset Global ETFs Holdings Ltd.7,120$124.6K0.00%−2,209−23.7%Reduced
Symmetry Investments LP10,000$175.0K0.01%+10,000New
Man Group plc10,225$178.9K0.00%+10,225New
Alliancebernstein L.P.10,500$183.8K0.00%00.0%Unchanged
Virtus Investment Advisers, Inc.10,614$185.7K0.05%+1,842+21.0%Added
Deutsche Bank AG10,923$191.2K0.00%+2,161+24.7%Added
MetLife Investment Management11,018$192.8K0.00%00.0%Unchanged
Wells Fargo & Company11,755$205.7K0.00%+812+7.4%Added
Invesco Ltd.11,788$206.3K0.00%+11,788New
Two Sigma Investments, LP13,587$237.8K0.00%+13,587New
Bridgeway Capital Management, LLC14,200$248.5K0.01%−15,000−51.4%Reduced
Silverarc Capital Management, LLC15,000$262.5K0.04%+15,000New
Walleye Capital LLC15,176$265.6K0.00%−55,157−78.4%Reduced
AQR Capital Management LLC15,764$275.9K0.00%−2,237−12.4%Reduced
Alps Advisors Inc16,840$294.7K0.00%−1,208−6.7%Reduced
Caption Management, LLC20,000$350.0K0.02%+20,000New
Barclays PLC21,626$378.5K0.00%−36,915−63.1%Reduced
Rhumbline Advisers21,821$381.9K0.00%−1,841−7.8%Reduced
Nuveen, LLC22,143$387.5K0.00%00.0%Unchanged
Balyasny Asset Management LLC25,641$448.7K0.00%+25,641New
Bank of America Corp26,616$465.8K0.00%−15,771−37.2%Reduced
Koa Wealth Management, LLC26,713$467.5K0.35%−5,039−15.9%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH28,461$498.1K0.00%+28,461New
Creative Planning28,732$502.8K0.00%+28,732New
SummitTX Capital, L.P.29,310$512.9K0.02%+29,310New
Weiss Asset Management LP30,823$539.4K0.01%+30,823New
Ghisallo Capital Management LLC38,250$669.4K0.02%+38,250New
XTX Topco Ltd38,378$671.6K0.03%+26,517+223.6%Added
Readystate Asset Management LP38,500$673.8K0.03%+38,500New
Boothbay Fund Management, LLC39,498$691.2K0.02%+39,498New
Morgan Stanley44,868$785.2K0.00%+20,860+86.9%Added
Bank of New York Mellon Corp47,735$835.4K0.00%+9,703+25.5%Added
Ikarian Capital, LLC48,071$841.2K0.19%+48,071New
Aaron Wealth Advisors50,000$875.0K0.05%00.0%Unchanged
Exome Asset Management LLC52,402$917.0K0.61%−10,674−16.9%Reduced
UBS Group AG60,725$1.06M0.00%+29,758+96.1%Added
Manufacturers Life Insurance Company, The68,376$1.20M0.00%−18,721−21.5%Reduced
FMR LLC68,976$1.21M0.00%+7,643+12.5%Added
Platinum Investment Management Ltd69,428$1.21M0.08%−43,315−38.4%Reduced
StemPoint Capital LP75,000$1.31M0.26%−66,021−46.8%Reduced
Murchinson Ltd.80,000$1.40M0.27%+80,000New
DAFNA Capital Management LLC85,000$1.49M0.37%+85,000New
Hudson Bay Capital Management LP85,000$1.49M0.01%+85,000New
Schroder Investment Management Group83,766$1.50M0.00%+83,766New
ExodusPoint Capital Management, LP100,000$1.75M0.02%+100,000New
Burkehill Global Management, LP100,000$1.75M0.10%+100,000New
TD Asset Management Inc118,792$2.08M0.00%−52,512−30.7%Reduced
Northern Trust Corp133,265$2.33M0.00%+17,671+15.3%Added
Affinity Asset Advisors, LLC165,000$2.89M0.27%+165,000New
Charles Schwab Investment Management Inc170,006$2.98M0.00%+62,523+58.2%Added
Polygon Management Ltd.177,840$3.11M0.45%+177,840New
Sectoral Asset Management Inc194,898$3.41M2.11%+3,073+1.6%Added
PFM Health Sciences, LP221,505$3.88M0.33%+221,505New
Longaeva Partners L.P.224,433$3.93M0.84%+224,433New
Opaleye Management Inc.253,000$4.43M0.63%+13,681+5.7%Added
Soleus Capital Management, L.P.275,000$4.81M0.26%+275,000New
Baker Bros. Advisors LP277,777$4.86M0.04%+277,777New
Rock Springs Capital Management LP282,624$4.95M0.29%+282,624New
Schonfeld Strategic Advisors LLC282,677$4.95M0.03%−348,736−55.2%Reduced
State Street Corp319,274$5.59M0.00%+54,155+20.4%Added
Goldman Sachs Group Inc358,121$6.27M0.00%+358,121New
Geode Capital Management, LLC473,932$8.30M0.00%+125,485+36.0%Added
Point72 Asset Management, L.P.627,667$11.0M0.02%−346,120−35.5%Reduced
TCG Crossover Management, LLC650,000$11.4M0.56%00.0%Unchanged