MBX Biosciences, Inc.
MBX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001776111
In the last 90 days, MBX Biosciences, Inc. insiders filed 0 open-market purchases and 1 sale; 172 institutions reported holding it in 13F filings for Q2 2026, worth $3.06B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in MBX Biosciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 157
- +21 vs. Q4 2025
- Shares held
- 52.5M
- +5.92M (+12.7%) vs. Q4 2025
- Total value
- $1.57B
- +$98.0M (+6.7%) vs. Q4 2025
- New holders
- 39
- 43 more added
- Sold out
- 18
- 47 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MBX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 172 | $3.06B |
| Q1 2026 | 157 | $1.57B |
| Q4 2025 | 138 | $1.53B |
| Q3 2025 | 118 | $836.4M |
| Q2 2025 | 88 | $420.3M |
| Q1 2025 | 79 | $263.2M |
| Q4 2024 | 63 | $606.5M |
| Q3 2024 | 45 | $784.1M |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding MBX Biosciences, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | 6,652,013 | $198.6M | 5.11% | 00.0% | Unchanged |
| OrbiMed Advisors LLC | 3,637,887 | $108.6M | 2.47% | −297,316−7.6% | Reduced |
| NEA Management Company, LLC | 3,614,486 | $107.9M | 6.13% | 00.0% | Unchanged |
| Wellington Management Group LLP | 3,191,824 | $95.3M | 0.02% | −158,137−4.7% | Reduced |
| BlackRock, Inc. | 2,941,406 | $87.8M | 0.00% | +21,650+0.7% | Added |
| FMR LLC | 2,936,684 | $87.7M | 0.00% | +2,920,938+18,550.3% | Added |
| Deep Track Capital, LP | 2,757,569 | $82.3M | 1.70% | −492,221−15.1% | Reduced |
| NVP Associates, LLC | 2,136,335 | $63.8M | 36.20% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 1,622,186 | $48.4M | 0.21% | +1,622,186 | New |
| Braidwell LP | 1,492,467 | $44.6M | 1.49% | +473,867+46.5% | Added |
| Vanguard Capital Management LLC | 1,477,592 | $44.1M | 0.00% | +1,477,592 | New |
| Aaron Wealth Advisors | 1,168,176 | $34.9M | 2.01% | +1,098,176+1,568.8% | Added |
| Cormorant Asset Management, LP | 1,120,000 | $33.4M | 1.69% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 1,029,007 | $30.7M | 0.00% | +188,501+22.4% | Added |
| Driehaus Capital Management LLC | 1,018,212 | $30.4M | 0.22% | −389,947−27.7% | Reduced |
| Kynam Capital Management, LP | 934,799 | $27.9M | 1.77% | 00.0% | Unchanged |
| Citadel Advisors LLC | 932,833 | $27.8M | 0.02% | +122,976+15.2% | Added |
| Woodline Partners LP | 900,063 | $26.9M | 0.10% | −100,000−10.0% | Reduced |
| Eventide Asset Management, LLC | 890,000 | $26.6M | 0.44% | 00.0% | Unchanged |
| Caligan Partners LP | 848,590 | $25.3M | 1.79% | +848,590 | New |
| Parkman Healthcare Partners LLC | 800,037 | $23.9M | 2.48% | −85,602−9.7% | Reduced |
| State Street Corp | 787,208 | $23.5M | 0.00% | +114,468+17.0% | Added |
| EcoR1 Capital, LLC | 777,000 | $23.2M | 0.99% | −1,346,604−63.4% | Reduced |
| Geode Capital Management, LLC | 670,385 | $20.0M | 0.00% | +20,994+3.2% | Added |
| TCG Crossover Management, LLC | 650,000 | $19.4M | 0.56% | 00.0% | Unchanged |
| Millennium Management LLC | 564,415 | $16.8M | 0.01% | +102,366+22.2% | Added |
| StemPoint Capital LP | 499,469 | $14.9M | 2.87% | +420,916+535.8% | Added |
| Goldman Sachs Group Inc | 457,945 | $13.7M | 0.00% | +126,007+38.0% | Added |
| UBS Group AG | 346,914 | $10.4M | 0.00% | +65,702+23.4% | Added |
| Candriam Luxembourg S.C.A. | 294,374 | $8.79M | 0.05% | +294,374 | New |
| Vanguard Portfolio Management LLC | 293,295 | $8.75M | 0.00% | +293,295 | New |
| D. E. Shaw & Co., Inc. | 288,889 | $8.62M | 0.01% | −382,949−57.0% | Reduced |
| Rock Springs Capital Management LP | 287,967 | $8.60M | 0.51% | +5,343+1.9% | Added |
| Opaleye Management Inc. | 260,000 | $7.76M | 1.02% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 214,908 | $6.42M | 0.00% | −7,272−3.3% | Reduced |
| Elmind Capital, LP | 211,000 | $6.30M | 1.79% | 00.0% | Unchanged |
| Northern Trust Corp | 210,575 | $6.29M | 0.00% | +19,694+10.3% | Added |
| Boothbay Fund Management, LLC | 208,049 | $6.21M | 0.15% | +208,049 | New |
| Soleus Capital Management, L.P. | 178,897 | $5.34M | 0.22% | −230,003−56.2% | Reduced |
| DAFNA Capital Management LLC | 175,465 | $5.24M | 1.19% | +10,200+6.2% | Added |
| Vanguard Fiduciary Trust Co | 170,154 | $5.08M | 0.00% | +170,154 | New |
| Goelzer Investment Management, Inc. | 164,172 | $4.90M | 0.24% | −57,500−25.9% | Reduced |
| Affinity Asset Advisors, LLC | 150,000 | $4.48M | 0.26% | −100,000−40.0% | Reduced |
| Polygon Management Ltd. | 145,480 | $4.34M | 0.85% | +2,153+1.5% | Added |
| JPMorgan Chase & Co | 147,057 | $3.96M | 0.00% | +132,412+904.1% | Added |
| Schonfeld Strategic Advisors LLC | 123,814 | $3.70M | 0.03% | −43,311−25.9% | Reduced |
| KVP Capital Advisors, LP | 121,524 | $3.63M | 2.71% | 00.0% | Unchanged |
| TD Asset Management Inc | 115,998 | $3.46M | 0.00% | +14,548+14.3% | Added |
| Two Sigma Investments, LP | 115,075 | $3.43M | 0.00% | −23,496−17.0% | Reduced |
| Burkehill Global Management, LP | 100,000 | $2.98M | 0.15% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 97,215 | $2.90M | 0.01% | +50,513+108.2% | Added |
| Manufacturers Life Insurance Company, The | 90,634 | $2.71M | 0.00% | +21,083+30.3% | Added |
| Nuveen, LLC | 81,792 | $2.44M | 0.00% | +6,227+8.2% | Added |
| Bank of New York Mellon Corp | 80,222 | $2.39M | 0.00% | +4,960+6.6% | Added |
| PFM Health Sciences, LP | 71,894 | $2.15M | 0.23% | −7,416−9.4% | Reduced |
| Victory Capital Management Inc | 71,028 | $2.12M | 0.00% | +71,028 | New |
| Marshall Wace, LLP | 62,703 | $1.87M | 0.00% | +62,703 | New |
| XTX Topco Ltd | 53,210 | $1.59M | 0.03% | +33,071+164.2% | Added |
| Schroder Investment Management Group | 57,322 | $1.54M | 0.00% | −16,414−22.3% | Reduced |
| Dimensional Fund Advisors LP | 46,753 | $1.40M | 0.00% | +46,753 | New |
| Swiss National Bank | 44,400 | $1.33M | 0.00% | +44,400 | New |
| Platinum Investment Management Ltd | 43,597 | $1.30M | 0.33% | 00.0% | Unchanged |
| Alps Advisors Inc | 36,550 | $1.09M | 0.01% | −322−0.9% | Reduced |
| Algert Global LLC | 36,020 | $1.08M | 0.02% | +36,020 | New |
| Creative Planning | 35,970 | $1.07M | 0.00% | +2,319+6.9% | Added |
| Exchange Traded Concepts, LLC | 34,264 | $1.02M | 0.01% | +34,264 | New |
| Rhumbline Advisers | 33,871 | $1.01M | 0.00% | +451+1.3% | Added |
| Alliancebernstein L.P. | 30,500 | $962.0K | 0.00% | +2,600+9.3% | Added |
| Morgan Stanley | 31,562 | $942.1K | 0.00% | −27,464−46.5% | Reduced |
| Bank of America Corp | 28,750 | $858.2K | 0.00% | −9,144−24.1% | Reduced |
| ExodusPoint Capital Management, LP | 28,087 | $838.4K | 0.01% | −28,918−50.7% | Reduced |
| Invesco Ltd. | 27,525 | $821.6K | 0.00% | +6,322+29.8% | Added |
| AQR Capital Management LLC | 27,387 | $817.5K | 0.00% | −4,022−12.8% | Reduced |
| Deutsche Bank AG | 22,950 | $685.1K | 0.00% | +2,923+14.6% | Added |
| California State Teachers Retirement System | 22,765 | $679.5K | 0.00% | +21,011+1,197.9% | Added |
| Swiss Life Asset Management Ltd | 12,130 | $657.2K | 0.00% | +12,130 | New |
| Cerity Partners LLC | 21,163 | $631.7K | 0.00% | −160−0.8% | Reduced |
| Legal & General Group Plc | 19,358 | $577.8K | 0.00% | +16,819+662.4% | Added |
| State of Wisconsin Investment Board | 19,262 | $575.0K | 0.00% | +19,262 | New |
| Koa Wealth Management, LLC | 17,913 | $534.7K | 0.39% | −500−2.7% | Reduced |
| Engineers Gate Manager LP | 17,380 | $518.8K | 0.01% | +17,380 | New |
| Qube Research & Technologies Ltd | 17,187 | $513.0K | 0.00% | −6,026−26.0% | Reduced |
| Vanguard Global Advisers, LLC | 16,028 | $478.4K | 0.00% | +16,028 | New |
| MetLife Investment Management | 16,018 | $478.1K | 0.00% | 00.0% | Unchanged |
| Vanguard Asset Management, Ltd | 14,752 | $440.3K | 0.00% | +14,752 | New |
| Optimize Financial Inc | 14,508 | $433.1K | 0.21% | +14,508 | New |
| Citigroup Inc | 13,499 | $402.9K | 0.00% | −2,892−17.6% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 13,325 | $397.8K | 0.00% | +67+0.5% | Added |
| Jump Financial, LLC | 12,700 | $379.1K | 0.01% | +12,700 | New |
| Barclays PLC | 11,838 | $353.4K | 0.00% | −40,853−77.5% | Reduced |
| HighVista Strategies LLC | 11,472 | $342.4K | 0.09% | +11,472 | New |
| Canada Pension Plan Investment Board | 10,900 | $325.4K | 0.00% | −700−6.0% | Reduced |
| Wells Fargo & Company | 10,762 | $321.2K | 0.00% | −21,169−66.3% | Reduced |
| BNP Paribas Arbitrage, SA | 10,384 | $310.0K | 0.00% | +3,600+53.1% | Added |
| Janus Henderson Group PLC | 10,300 | $308.2K | 0.00% | +10,300 | New |
| Verition Fund Management LLC | 10,222 | $305.1K | 0.00% | −47,353−82.2% | Reduced |
| Aquatic Capital Management LLC | 10,155 | $303.1K | 0.01% | +10,155 | New |
| Susquehanna International Group, LLP | 9,487 | $283.2K | 0.00% | −67,041−87.6% | Reduced |
| Virtus Investment Advisers, Inc. | 9,131 | $272.6K | 0.08% | +221+2.5% | Added |
| New York State Common Retirement Fund | 9,000 | $268.6K | 0.00% | +4,700+109.3% | Added |