Skip to main content

MBX Biosciences, Inc.

MBX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001776111

In the last 90 days, MBX Biosciences, Inc. insiders filed 0 open-market purchases and 1 sale; 172 institutions reported holding it in 13F filings for Q2 2026, worth $3.06B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in MBX Biosciences, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
172
+17 vs. Q1 2026
Shares held
55.5M
+2.46M (+4.6%) vs. Q1 2026
Total value
$3.06B
+$1.48B (+93.5%) vs. Q1 2026
New holders
38
64 more added
Sold out
21
49 more reduced

2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MBX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 172 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 45 institutionsQ4 2024: 63 institutionsQ1 2025: 79 institutionsQ2 2025: 88 institutionsQ3 2025: 118 institutionsQ4 2025: 138 institutionsQ1 2026: 157 institutionsQ2 2026: 172 institutions
Value heldQ2 2026: $3.06B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $784.1MQ4 2024: $606.5MQ1 2025: $263.2MQ2 2025: $420.7MQ3 2025: $836.5MQ4 2025: $1.53BQ1 2026: $1.58BQ2 2026: $3.06B
Institutions holding MBX and their total value by quarter
QuarterHoldersValue
Q2 2026172$3.06B
Q1 2026157$1.58B
Q4 2025138$1.53B
Q3 2025118$836.5M
Q2 202588$420.7M
Q1 202579$263.2M
Q4 202463$606.5M
Q3 202445$784.1M
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding MBX Biosciences, Inc.; share changes are against Q1 2026.

Institutions holding MBX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Frazier Life Sciences Management, L.P.6,652,013$367.2M8.00%00.0%Unchanged
FMR LLC5,322,885$293.8M0.01%+2,386,201+81.3%Added
Wellington Management Group LLP4,977,523$274.8M0.05%+1,785,699+55.9%Added
NEA Management Company, LLC3,614,486$199.5M12.56%00.0%Unchanged
OrbiMed Advisors LLC3,428,736$189.3M3.58%−209,151−5.7%Reduced
BlackRock, Inc.3,323,672$183.5M0.00%+382,266+13.0%Added
Paradigm Biocapital Advisors LP2,508,015$138.4M2.59%+2,508,015New
NVP Associates, LLC2,136,335$117.9M35.93%00.0%Unchanged
Deep Track Capital, LP1,732,569$95.6M1.41%−1,025,000−37.2%Reduced
Polar Capital Holdings Plc1,608,514$88.8M0.25%−13,672−0.8%Reduced
Vanguard Capital Management LLC1,477,388$81.6M0.00%−2040.0%Reduced
Aaron Wealth Advisors1,167,799$64.5M3.27%−3770.0%Reduced
Driehaus Capital Management LLC1,056,579$58.3M0.34%+38,367+3.8%Added
Kynam Capital Management, LP934,799$51.6M2.85%00.0%Unchanged
Woodline Partners LP900,092$49.7M0.15%+290.0%Added
Eventide Asset Management, LLC873,492$48.2M0.64%−16,508−1.9%Reduced
State Street Corp864,466$47.7M0.00%+77,258+9.8%Added
Price T Rowe Associates Inc814,807$45.0M0.00%−214,200−20.8%Reduced
Parkman Healthcare Partners LLC800,173$44.2M4.54%+1360.0%Added
Geode Capital Management, LLC773,072$42.7M0.00%+102,687+15.3%Added
Braidwell LP710,880$39.2M1.45%−781,587−52.4%Reduced
TCG Crossover Management, LLC650,000$35.9M0.86%00.0%Unchanged
Cormorant Asset Management, LP550,000$30.4M1.56%−570,000−50.9%Reduced
Soleus Capital Management, L.P.515,279$28.4M0.98%+336,382+188.0%Added
Goldman Sachs Group Inc459,005$25.3M0.00%+1,060+0.2%Added
Marshall Wace, LLP401,885$22.2M0.02%+339,182+540.9%Added
EcoR1 Capital, LLC388,500$21.4M1.06%−388,500−50.0%Reduced
Vanguard Portfolio Management LLC346,717$19.1M0.00%+53,422+18.2%Added
Bank of America Corp298,927$16.5M0.00%+270,177+939.7%Added
Rock Springs Capital Management LP298,218$16.5M0.80%+10,251+3.6%Added
Candriam Luxembourg S.C.A.289,893$16.0M0.07%−4,481−1.5%Reduced
UBS Group AG272,747$15.1M0.00%−74,167−21.4%Reduced
Opaleye Management Inc.260,000$14.4M1.30%00.0%Unchanged
Franklin Resources Inc252,665$13.9M0.00%+252,665New
Schonfeld Strategic Advisors LLC248,670$13.7M0.07%+124,856+100.8%Added
Morgan Stanley248,558$13.7M0.00%+216,996+687.5%Added
Northern Trust Corp246,678$13.6M0.00%+36,103+17.1%Added
Dimensional Fund Advisors LP233,700$12.9M0.00%+186,947+399.9%Added
Charles Schwab Investment Management Inc233,095$12.9M0.00%+18,187+8.5%Added
Millennium Management LLC226,151$12.5M0.01%−338,264−59.9%Reduced
Polygon Management Ltd.203,543$11.2M1.83%+58,063+39.9%Added
Vanguard Fiduciary Trust Co201,429$11.1M0.00%+31,275+18.4%Added
Caligan Partners LP200,000$11.0M0.53%−648,590−76.4%Reduced
D. E. Shaw & Co., Inc.182,767$10.1M0.01%−106,122−36.7%Reduced
JPMorgan Chase & Co139,611$7.52M0.00%−7,446−5.1%Reduced
KVP Capital Advisors, LP121,524$6.71M4.92%00.0%Unchanged
Two Sigma Investments, LP113,475$6.26M0.00%−1,600−1.4%Reduced
Burkehill Global Management, LP100,000$5.52M0.20%00.0%Unchanged
Nuveen, LLC98,733$5.45M0.00%+16,941+20.7%Added
TD Asset Management Inc95,598$5.28M0.00%−20,400−17.6%Reduced
Elmind Capital, LP91,000$5.02M1.26%−120,000−56.9%Reduced
Bank of New York Mellon Corp88,927$4.91M0.00%+8,705+10.9%Added
Prudential Financial Inc88,045$4.86M0.01%+88,045New
Barclays PLC87,854$4.85M0.00%+76,016+642.1%Added
Affinity Asset Advisors, LLC75,000$4.14M0.20%−75,000−50.0%Reduced
PFM Health Sciences, LP70,971$3.92M0.34%−923−1.3%Reduced
Boothbay Fund Management, LLC70,353$3.88M0.07%−137,696−66.2%Reduced
Manufacturers Life Insurance Company, The66,112$3.65M0.00%−24,522−27.1%Reduced
Moore Capital Management, LP64,893$3.58M0.08%+64,893New
Rhenman & Partners Asset Management AB62,000$3.42M0.32%+62,000New
Invesco Ltd.50,678$2.80M0.00%+23,153+84.1%Added
Alps Advisors Inc48,012$2.65M0.01%+11,462+31.4%Added
Platinum Investment Management Ltd43,597$2.41M0.59%00.0%Unchanged
Swiss National Bank42,900$2.37M0.00%−1,500−3.4%Reduced
Ensign Peak Advisors, Inc42,156$2.33M0.00%+42,156New
Algert Global LLC42,070$2.32M0.03%+6,050+16.8%Added
Creative Planning39,524$2.18M0.00%+3,554+9.9%Added
Rhumbline Advisers37,196$2.05M0.00%+3,325+9.8%Added
Deutsche Bank AG31,693$1.75M0.00%+8,743+38.1%Added
Wells Fargo & Company28,313$1.56M0.00%+17,551+163.1%Added
Exchange Traded Concepts, LLC27,421$1.51M0.01%−6,843−20.0%Reduced
Susquehanna International Group, LLP26,684$1.47M0.00%+17,197+181.3%Added
Voya Investment Management LLC26,132$1.44M0.00%+26,132New
Universal- Beteiligungs- und Servicegesellschaft mbH25,800$1.42M0.00%+25,800New
Teachers Retirement System of the State of Kentucky25,377$1.40M0.01%+25,377New
Citigroup Inc25,122$1.39M0.00%+11,623+86.1%Added
California State Teachers Retirement System23,376$1.29M0.00%+611+2.7%Added
American Century Companies Inc22,680$1.25M0.00%+13,954+159.9%Added
AQR Capital Management LLC22,591$1.25M0.00%−4,796−17.5%Reduced
Legal & General Group Plc21,583$1.19M0.00%+2,225+11.5%Added
UBS Asset Management Americas Inc21,344$1.18M0.00%+14,106+194.9%Added
Cerity Partners LLC20,997$1.16M0.00%−166−0.8%Reduced
Vanguard Global Advisers, LLC18,969$1.05M0.00%+2,941+18.3%Added
MetLife Investment Management18,250$1.01M0.00%+2,232+13.9%Added
Russell Investments Group, Ltd.18,162$1.00M0.00%+14,306+371.0%Added
Koa Wealth Management, LLC17,113$944.6K0.64%−800−4.5%Reduced
Alliancebernstein L.P.31,000$925.4K0.00%+500+1.6%Added
State of Wisconsin Investment Board15,971$881.6K0.00%−3,291−17.1%Reduced
Vanguard Asset Management, Ltd14,752$814.3K0.00%00.0%Unchanged
Optimize Financial Inc14,458$798.1K0.29%−50−0.3%Reduced
Sound Capital Solutions LLC14,458$798.1K0.19%+14,458New
Mirae Asset Global ETFs Holdings Ltd.14,292$788.9K0.00%+967+7.3%Added
DAFNA Capital Management LLC11,809$651.9K0.12%−163,656−93.3%Reduced
HighVista Strategies LLC11,634$642.2K0.15%+162+1.4%Added
New York State Common Retirement Fund11,000$607.2K0.00%+2,000+22.2%Added
Jupiter Topco LLC10,300$568.3K0.00%+10,300New
Fred Alger Management, LLC9,877$545.2K0.00%+9,877New
BNP Paribas Arbitrage, SA9,860$544.3K0.00%−524−5.0%Reduced
State Board of Administration of Florida Retirement System9,777$539.7K0.00%+9,777New
Virtus Investment Advisers, Inc.9,215$508.7K0.12%+84+0.9%Added