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Lexeo Therapeutics, Inc.

LXEO
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001907108

In the last 90 days, Lexeo Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 141 institutions reported holding it in 13F filings for Q2 2026, worth $410.9M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Lexeo Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
109
+19 vs. Q2 2025
Shares held
49.3M
+7.08M (+16.8%) vs. Q2 2025
Total value
$327.5M
+$157.6M (+92.8%) vs. Q2 2025
New holders
26
50 more added
Sold out
7
15 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXEO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 109 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 31 institutionsQ1 2024: 54 institutionsQ2 2024: 60 institutionsQ3 2024: 69 institutionsQ4 2024: 90 institutionsQ1 2025: 88 institutionsQ2 2025: 90 institutionsQ3 2025: 109 institutionsQ4 2025: 146 institutionsQ1 2026: 139 institutionsQ2 2026: 141 institutions
Value heldQ3 2025: $327.5M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $217.1MQ1 2024: $361.5MQ2 2024: $426.3MQ3 2024: $268.8MQ4 2024: $194.2MQ1 2025: $100.0MQ2 2025: $169.9MQ3 2025: $327.5MQ4 2025: $759.2MQ1 2026: $458.7MQ2 2026: $410.9M
Institutions holding LXEO and their total value by quarter
QuarterHoldersValue
Q2 2026141$410.9M
Q1 2026139$458.7M
Q4 2025146$759.2M
Q3 2025109$327.5M
Q2 202590$169.9M
Q1 202588$100.0M
Q4 202490$194.2M
Q3 202469$268.8M
Q2 202460$426.3M
Q1 202454$361.5M
Q4 202331$217.1M
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Lexeo Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding LXEO in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc2,226,290$14.8M0.00%+223,424+11.2%Added
Millennium Management LLC2,313,642$15.4M0.01%−522,650−18.4%Reduced
Woodline Partners LP2,572,162$17.1M0.08%00.0%Unchanged
Vestal Point Capital, LP3,250,000$21.6M0.98%+21,839+0.7%Added
Citadel Advisors LLC3,719,043$24.7M0.02%+111,076+3.1%Added
Affinity Asset Advisors, LLC3,870,527$25.7M2.39%+281,172+7.8%Added
Balyasny Asset Management LLC3,913,788$26.0M0.05%−95,349−2.4%Reduced
Frazier Life Sciences Management, L.P.4,424,725$29.4M0.88%00.0%Unchanged
Janus Henderson Group PLC6,105,527$40.5M0.02%+2,421,144+65.7%Added
Omega Fund Management, LLC0$00.00%−1,184,636−100.0%Sold out
Ally Bridge Group (NY) LLC0$00.00%−867,302−100.0%Sold out
Quadrature Capital Ltd0$00.00%−29,779−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−14,528−100.0%Sold out
FNY Investment Advisers, LLC0$00.00%−5,000−100.0%Sold out
Skopos Labs, Inc.0$00.00%−3,852−100.0%Sold out
Caitong International Asset Management Co., Ltd0$00.00%−1−100.0%Sold out