Opus Genetics, Inc.
IRD- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001228627
In the last 90 days, Opus Genetics, Inc. insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $236.4M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Opus Genetics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 79
- +22 vs. Q4 2025
- Shares held
- 45.4M
- +19.9M (+78.2%) vs. Q4 2025
- Total value
- $203.8M
- +$152.6M (+297.9%) vs. Q4 2025
- New holders
- 28
- 16 more added
- Sold out
- 6
- 15 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IRD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $236.4M |
| Q1 2026 | 79 | $203.8M |
| Q4 2025 | 59 | $55.9M |
| Q3 2025 | 48 | $31.9M |
| Q2 2025 | 43 | $16.5M |
| Q1 2025 | 46 | $14.7M |
| Q4 2024 | 43 | $4.38M |
| Q3 2024 | 38 | $3.32M |
| Q2 2024 | 37 | $4.13M |
| Q1 2024 | 49 | $6.78M |
| Q4 2023 | 50 | $11.2M |
| Q3 2023 | 50 | $12.6M |
| Q2 2023 | 49 | $16.0M |
| Q1 2023 | 41 | $13.0M |
| Q4 2022 | 35 | $10.9M |
| Q3 2022 | 37 | $5.69M |
| Q2 2022 | 38 | $4.62M |
| Q1 2022 | 41 | $6.69M |
| Q4 2021 | 40 | $8.07M |
| Q3 2021 | 30 | $8.62M |
| Q2 2021 | 36 | $5.61M |
| Q1 2021 | 27 | $5.27M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Opus Genetics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Caligan Partners LP | 6,075,028 | $27.6M | 1.96% | +6,075,028 | New |
| Adage Capital Partners GP, L.L.C. | 6,029,775 | $27.4M | 0.04% | +4,924,779+445.7% | Added |
| BIOS Capital Management, LP | 3,683,429 | $16.8M | 31.70% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 2,718,029 | $12.4M | 0.02% | 00.0% | Unchanged |
| Millennium Management LLC | 2,630,432 | $12.0M | 0.01% | +627,882+31.4% | Added |
| Vanguard Capital Management LLC | 2,449,987 | $11.1M | 0.00% | +2,449,987 | New |
| Marshall Wace, LLP | 2,313,380 | $10.5M | 0.01% | +2,155,732+1,367.4% | Added |
| Boxer Capital Management, LLC | 2,250,000 | $10.2M | 1.34% | +2,250,000 | New |
| ADAR1 Capital Management, LLC | 1,849,004 | $8.41M | 0.51% | +1,809,004+4,522.5% | Added |
| Perceptive Advisors LLC | 1,835,842 | $8.35M | 0.16% | −2,489,158−57.6% | Reduced |
| Nantahala Capital Management, LLC | 1,681,330 | $7.65M | 0.48% | −3,100,000−64.8% | Reduced |
| Woodline Partners LP | 1,354,030 | $6.16M | 0.02% | +1,354,030 | New |
| Boothbay Fund Management, LLC | 1,189,113 | $5.41M | 0.13% | +1,189,113 | New |
| Farallon Capital Management, L.L.C. | 1,000,000 | $4.55M | 0.03% | +1,000,000 | New |
| Susquehanna International Group, LLP | 823,383 | $3.75M | 0.00% | +621,748+308.4% | Added |
| Bleichroeder LP | 736,842 | $3.35M | 0.58% | 00.0% | Unchanged |
| Mink Brook Asset Management LLC | 590,552 | $2.69M | 1.50% | −1,075,079−64.5% | Reduced |
| Geode Capital Management, LLC | 538,347 | $2.45M | 0.00% | +33,364+6.6% | Added |
| Trails Edge Capital Partners, LP | 500,000 | $2.27M | 0.54% | +500,000 | New |
| Opaleye Management Inc. | 1,120,000 | $2.25M | 0.30% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 388,491 | $1.77M | 0.00% | +388,491 | New |
| Goldman Sachs Group Inc | 326,809 | $1.49M | 0.00% | +326,809 | New |
| Great Point Partners LLC | 324,340 | $1.48M | 0.36% | +324,340 | New |
| Vanguard Fiduciary Trust Co | 281,801 | $1.28M | 0.00% | +281,801 | New |
| UBS Group AG | 257,649 | $1.17M | 0.00% | +167,831+186.9% | Added |
| State Street Corp | 199,953 | $909.8K | 0.00% | +26,700+15.4% | Added |
| Jane Street Group, LLC | 158,103 | $719.4K | 0.00% | +158,103 | New |
| BlackRock, Inc. | 147,740 | $672.2K | 0.00% | +5,843+4.1% | Added |
| Voleon Capital Management LP | 143,796 | $654.3K | 0.01% | +143,796 | New |
| Seven Fleet Capital Management LP | 134,242 | $610.8K | 0.19% | +134,242 | New |
| Creative Planning | 128,366 | $584.1K | 0.00% | 00.0% | Unchanged |
| Citadel Advisors LLC | 120,900 | $550.1K | 0.00% | −59,821−33.1% | Reduced |
| Two Sigma Investments, LP | 108,641 | $494.3K | 0.00% | −42,671−28.2% | Reduced |
| Northern Trust Corp | 94,415 | $429.6K | 0.00% | +6,968+8.0% | Added |
| Texas Capital Bank Wealth Management Services Inc | 88,500 | $402.7K | 0.02% | +10,500+13.5% | Added |
| Simplex Trading, LLC | 82,480 | $375.3K | 0.01% | +73,417+810.1% | Added |
| Renaissance Technologies LLC | 73,209 | $333.1K | 0.00% | −53,100−42.0% | Reduced |
| Stonepine Capital Management, LLC | 68,688 | $312.5K | 0.27% | +68,688 | New |
| Regency Capital Management Inc. | 68,000 | $309.4K | 0.14% | +22,000+47.8% | Added |
| HRT Financial LP | 67,663 | $307.0K | 0.00% | +67,663 | New |
| Bank of America Corp | 67,015 | $304.9K | 0.00% | +64,829+2,965.6% | Added |
| Palogic Value Management, L.P. | 65,000 | $295.8K | 0.13% | +65,000 | New |
| Brevan Howard Capital Management LP | 61,313 | $279.0K | 0.00% | +61,313 | New |
| Bridgeway Capital Management, LLC | 42,065 | $191.4K | 0.00% | 00.0% | Unchanged |
| Empowered Funds, LLC | 42,065 | $191.4K | 0.00% | 00.0% | Unchanged |
| Mangrove Partners | 41,717 | $189.8K | 0.02% | +41,717 | New |
| Omers Administration Corp | 41,600 | $189.3K | 0.00% | −46,300−52.7% | Reduced |
| Morgan Stanley | 39,522 | $179.8K | 0.00% | +10,857+37.9% | Added |
| Charles Schwab Investment Management Inc | 35,000 | $159.3K | 0.00% | +35,000 | New |
| Captrust Financial Advisors | 32,000 | $145.6K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 28,741 | $130.8K | 0.00% | +28,741 | New |
| nVerses Capital, LLC | 28,564 | $130.0K | 0.12% | +28,564 | New |
| Vanguard Global Advisers, LLC | 22,225 | $101.1K | 0.00% | +22,225 | New |
| Miller Financial Services LLC | 22,000 | $100.1K | 0.11% | +12,000+120.0% | Added |
| Raymond James Financial Inc | 19,508 | $88.8K | 0.00% | −1,000−4.9% | Reduced |
| Persistent Asset Partners Ltd | 17,919 | $81.5K | 0.03% | +17,919 | New |
| XTX Topco Ltd | 16,704 | $76.0K | 0.00% | −7,033−29.6% | Reduced |
| James Investment Research Inc | 16,364 | $74.5K | 0.01% | 00.0% | Unchanged |
| GWM Advisors LLC | 16,364 | $74.5K | 0.00% | 00.0% | Unchanged |
| Bedel Financial Consulting, Inc. | 15,000 | $68.3K | 0.01% | 00.0% | Unchanged |
| Kestra Private Wealth Services, LLC | 12,800 | $58.2K | 0.00% | −3,200−20.0% | Reduced |
| Blair William & Co | 12,466 | $56.7K | 0.00% | −15,000−54.6% | Reduced |
| Stokes Family Office, LLC | 12,120 | $55.1K | 0.01% | 00.0% | Unchanged |
| Sanders Morris Harris LLC | 12,000 | $54.6K | 0.01% | +12,000 | New |
| First City Capital Management, Inc. | 11,836 | $53.9K | 0.03% | 00.0% | Unchanged |
| Group One Trading, L.P. | 10,594 | $48.2K | 0.00% | +10,594 | New |
| Annandale Capital, LLC | 10,000 | $46.0K | 0.01% | 00.0% | Unchanged |
| Reliant Investment Partners, LLC | 10,000 | $45.5K | 0.04% | 00.0% | Unchanged |
| Hilton Head Capital Partners, LLC | 4,472 | $20.3K | 0.01% | 00.0% | Unchanged |
| Wells Fargo & Company | 3,785 | $17.2K | 0.00% | −238,086−98.4% | Reduced |
| Farther Finance Advisors, LLC | 2,300 | $10.8K | 0.00% | +2,300 | New |
| Advisor Group Holdings, Inc. | 2,200 | $10.0K | 0.00% | −11,700−84.2% | Reduced |
| National Bank of Canada | 2,014 | $9.14K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 1,900 | $8.64K | 0.00% | 00.0% | Unchanged |
| International Assets Investment Management, LLC | 521 | $2.44K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 530 | $2.41K | 0.00% | −2,044−79.4% | Reduced |
| FMR LLC | 8 | $36 | 0.00% | +8 | New |
| Allworth Financial LP | 5 | $23 | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 5 | $0 | 0.00% | −294−98.3% | Reduced |
| Voss Capital, LLC | 0 | $0 | 0.00% | −441,891−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −39,978−100.0% | Sold out |
| Johnson Investment Counsel Inc | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −16,810−100.0% | Sold out |
| Occudo Quantitative Strategies LP | 0 | $0 | 0.00% | −12,205−100.0% | Sold out |
| Citigroup Inc | 0 | $0 | 0.00% | −496−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |
| Comerica Bank | – | – | – | – | Not filed |