Opus Genetics, Inc.
IRD- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001228627
In the last 90 days, Opus Genetics, Inc. insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $236.4M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Opus Genetics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 48
- +6 vs. Q2 2025
- Shares held
- 19.0M
- +1.55M (+8.9%) vs. Q2 2025
- Total value
- $31.9M
- +$15.5M (+93.9%) vs. Q2 2025
- New holders
- 10
- 12 more added
- Sold out
- 4
- 4 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IRD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $236.4M |
| Q1 2026 | 79 | $203.8M |
| Q4 2025 | 59 | $55.9M |
| Q3 2025 | 48 | $31.9M |
| Q2 2025 | 43 | $16.5M |
| Q1 2025 | 46 | $14.7M |
| Q4 2024 | 43 | $4.38M |
| Q3 2024 | 38 | $3.32M |
| Q2 2024 | 37 | $4.13M |
| Q1 2024 | 49 | $6.78M |
| Q4 2023 | 50 | $11.2M |
| Q3 2023 | 50 | $12.6M |
| Q2 2023 | 49 | $16.0M |
| Q1 2023 | 41 | $13.0M |
| Q4 2022 | 35 | $10.9M |
| Q3 2022 | 37 | $5.69M |
| Q2 2022 | 38 | $4.62M |
| Q1 2022 | 41 | $6.69M |
| Q4 2021 | 40 | $8.07M |
| Q3 2021 | 30 | $8.62M |
| Q2 2021 | 36 | $5.61M |
| Q1 2021 | 27 | $5.27M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Opus Genetics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 4,325,000 | $7.14M | 0.21% | 00.0% | Unchanged |
| BIOS Capital Management, LP | 3,683,429 | $6.59M | 7.42% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 3,345,923 | $5.52M | 0.34% | 00.0% | Unchanged |
| Vanguard Group Inc | 1,342,025 | $2.21M | 0.00% | +349,825+35.3% | Added |
| Mink Brook Asset Management LLC | 1,237,947 | $2.04M | 1.38% | +40,331+3.4% | Added |
| Opaleye Management Inc. | 1,100,000 | $1.81M | 0.26% | −120,000−9.8% | Reduced |
| Adage Capital Partners GP, L.L.C. | 954,996 | $1.58M | 0.00% | +954,996 | New |
| Bleichroeder LP | 736,842 | $1.22M | 0.24% | 00.0% | Unchanged |
| Voss Capital, LLC | 562,377 | $927.9K | 0.05% | +21,218+3.9% | Added |
| Geode Capital Management, LLC | 468,937 | $773.8K | 0.00% | +113,260+31.8% | Added |
| Renaissance Technologies LLC | 173,809 | $286.8K | 0.00% | +20,500+13.4% | Added |
| State Street Corp | 145,873 | $240.7K | 0.00% | +75,400+107.0% | Added |
| Creative Planning | 128,366 | $211.8K | 0.00% | +128,366 | New |
| Citadel Advisors LLC | 113,416 | $187.1K | 0.00% | +113,416 | New |
| Two Sigma Investments, LP | 108,338 | $178.8K | 0.00% | +68,148+169.6% | Added |
| Northern Trust Corp | 68,228 | $112.6K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 51,757 | $85.4K | 0.00% | +35,949+227.4% | Added |
| BlackRock, Inc. | 46,094 | $76.1K | 0.00% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 42,065 | $69.4K | 0.00% | 00.0% | Unchanged |
| Empowered Funds, LLC | 42,065 | $69.4K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 32,847 | $54.0K | 0.00% | +32,847 | New |
| Captrust Financial Advisors | 32,000 | $52.8K | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 28,606 | $47.2K | 0.00% | 00.0% | Unchanged |
| Blair William & Co | 24,466 | $40.4K | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Inc | 22,508 | $37.1K | 0.00% | +11,000+95.6% | Added |
| HRT Financial LP | 20,677 | $34.0K | 0.00% | +20,677 | New |
| Susquehanna International Group, LLP | 20,213 | $33.4K | 0.00% | +2,910+16.8% | Added |
| Kestra Private Wealth Services, LLC | 19,000 | $31.4K | 0.00% | 00.0% | Unchanged |
| Two Sigma Securities, LLC | 17,746 | $29.3K | 0.00% | +17,746 | New |
| James Investment Research Inc | 16,364 | $27.0K | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 16,364 | $27.0K | 0.00% | 00.0% | Unchanged |
| Bedel Financial Consulting, Inc. | 15,000 | $24.8K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 13,904 | $23.7K | 0.00% | +40.0% | Added |
| Prudential Financial Inc | 13,100 | $21.6K | 0.00% | +13,100 | New |
| Stokes Family Office, LLC | 12,120 | $20.0K | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 12,000 | $19.8K | 0.00% | 00.0% | Unchanged |
| Reliant Investment Partners, LLC | 10,000 | $18.8K | 0.01% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 10,200 | $16.8K | 0.00% | +10,200 | New |
| Annandale Capital, LLC | 10,000 | $16.5K | 0.00% | +10,000 | New |
| Wells Fargo & Company | 3,785 | $6.25K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 2,582 | $4.26K | 0.00% | −1,000−27.9% | Reduced |
| National Bank of Canada | 2,014 | $3.30K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 1,900 | $3.13K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 884 | $1.46K | 0.00% | −27,226−96.9% | Reduced |
| Bank of America Corp | 383 | $632 | 0.00% | +98+34.4% | Added |
| MAI Capital Management | 123 | $203 | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 1 | $2 | 0.00% | +1 | New |
| Royal Bank of Canada | 30 | $0 | 0.00% | −127,220−100.0% | Reduced |
| Millennium Management LLC | 0 | $0 | 0.00% | −127,844−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −79,346−100.0% | Sold out |
| Tower Research Capital LLC (TRC) | 0 | $0 | 0.00% | −6,698−100.0% | Sold out |
| CarsonAllaria Wealth Management, Ltd. | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| Financial Gravity Companies, Inc. | – | – | – | – | Not filed |