Opus Genetics, Inc.
IRD- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001228627
In the last 90 days, Opus Genetics, Inc. insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $236.4M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Opus Genetics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 59
- +11 vs. Q3 2025
- Shares held
- 27.8M
- +8.78M (+46.1%) vs. Q3 2025
- Total value
- $55.9M
- +$24.0M (+75.1%) vs. Q3 2025
- New holders
- 16
- 19 more added
- Sold out
- 5
- 8 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IRD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $236.4M |
| Q1 2026 | 79 | $203.8M |
| Q4 2025 | 59 | $55.9M |
| Q3 2025 | 48 | $31.9M |
| Q2 2025 | 43 | $16.5M |
| Q1 2025 | 46 | $14.7M |
| Q4 2024 | 43 | $4.38M |
| Q3 2024 | 38 | $3.32M |
| Q2 2024 | 37 | $4.13M |
| Q1 2024 | 49 | $6.78M |
| Q4 2023 | 50 | $11.2M |
| Q3 2023 | 50 | $12.6M |
| Q2 2023 | 49 | $16.0M |
| Q1 2023 | 41 | $13.0M |
| Q4 2022 | 35 | $10.9M |
| Q3 2022 | 37 | $5.69M |
| Q2 2022 | 38 | $4.62M |
| Q1 2022 | 41 | $6.69M |
| Q4 2021 | 40 | $8.07M |
| Q3 2021 | 30 | $8.62M |
| Q2 2021 | 36 | $5.61M |
| Q1 2021 | 27 | $5.27M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Opus Genetics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 4,781,330 | $9.61M | 0.57% | +1,435,407+42.9% | Added |
| Perceptive Advisors LLC | 4,325,000 | $8.69M | 0.16% | 00.0% | Unchanged |
| BIOS Capital Management, LP | 3,683,429 | $7.40M | 8.96% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 2,718,029 | $5.46M | 0.01% | +2,718,029 | New |
| Vanguard Group Inc | 2,322,897 | $4.67M | 0.00% | +980,872+73.1% | Added |
| Millennium Management LLC | 2,002,550 | $4.03M | 0.00% | +2,002,550 | New |
| Mink Brook Asset Management LLC | 1,665,631 | $3.35M | 2.12% | +427,684+34.5% | Added |
| Opaleye Management Inc. | 1,120,000 | $2.25M | 0.30% | +20,000+1.8% | Added |
| Adage Capital Partners GP, L.L.C. | 1,104,996 | $2.22M | 0.00% | +150,000+15.7% | Added |
| Bleichroeder LP | 736,842 | $1.48M | 0.26% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 504,983 | $1.02M | 0.00% | +36,046+7.7% | Added |
| Voss Capital, LLC | 441,891 | $888.2K | 0.05% | −120,486−21.4% | Reduced |
| Wells Fargo & Company | 241,871 | $486.2K | 0.00% | +238,086+6,290.3% | Added |
| Susquehanna International Group, LLP | 201,635 | $405.3K | 0.00% | +181,422+897.6% | Added |
| Citadel Advisors LLC | 180,721 | $363.3K | 0.00% | +67,305+59.3% | Added |
| State Street Corp | 173,253 | $348.2K | 0.00% | +27,380+18.8% | Added |
| Marshall Wace, LLP | 157,648 | $316.9K | 0.00% | +157,648 | New |
| Two Sigma Investments, LP | 151,312 | $304.1K | 0.00% | +42,974+39.7% | Added |
| BlackRock, Inc. | 141,897 | $285.2K | 0.00% | +95,803+207.8% | Added |
| Creative Planning | 128,366 | $258.0K | 0.00% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 126,309 | $253.9K | 0.00% | −47,500−27.3% | Reduced |
| UBS Group AG | 89,818 | $180.5K | 0.00% | +88,934+10,060.4% | Added |
| Omers Administration Corp | 87,900 | $176.7K | 0.00% | +87,900 | New |
| Northern Trust Corp | 87,447 | $175.8K | 0.00% | +19,219+28.2% | Added |
| Texas Capital Bank Wealth Management Services Inc | 78,000 | $156.8K | 0.01% | +78,000 | New |
| Regency Capital Management Inc. | 46,000 | $92.5K | 0.04% | +46,000 | New |
| Bridgeway Capital Management, LLC | 42,065 | $84.6K | 0.00% | 00.0% | Unchanged |
| Empowered Funds, LLC | 42,065 | $84.6K | 0.00% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 40,000 | $80.4K | 0.01% | +40,000 | New |
| Qube Research & Technologies Ltd | 39,978 | $80.4K | 0.00% | +39,978 | New |
| Captrust Financial Advisors | 32,000 | $64.3K | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 28,665 | $57.6K | 0.00% | +59+0.2% | Added |
| Blair William & Co | 27,466 | $55.2K | 0.00% | +3,000+12.3% | Added |
| XTX Topco Ltd | 23,737 | $47.7K | 0.00% | −28,020−54.1% | Reduced |
| Raymond James Financial Inc | 20,508 | $41.2K | 0.00% | −2,000−8.9% | Reduced |
| Johnson Investment Counsel Inc | 20,000 | $40.2K | 0.00% | +20,000 | New |
| Virtu Financial LLC | 16,810 | $34.0K | 0.00% | +16,810 | New |
| James Investment Research Inc | 16,364 | $32.9K | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 16,364 | $32.9K | 0.00% | 00.0% | Unchanged |
| Kestra Private Wealth Services, LLC | 16,000 | $32.2K | 0.00% | −3,000−15.8% | Reduced |
| Bedel Financial Consulting, Inc. | 15,000 | $30.1K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 13,900 | $27.9K | 0.00% | −40.0% | Reduced |
| Occudo Quantitative Strategies LP | 12,205 | $24.5K | 0.00% | +12,205 | New |
| Stokes Family Office, LLC | 12,120 | $24.4K | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 12,000 | $24.1K | 0.00% | 00.0% | Unchanged |
| First City Capital Management, Inc. | 11,836 | $23.8K | 0.01% | +11,836 | New |
| Reliant Investment Partners, LLC | 10,000 | $20.1K | 0.02% | 00.0% | Unchanged |
| Miller Financial Services LLC | 10,000 | $20.1K | 0.02% | +10,000 | New |
| Annandale Capital, LLC | 10,000 | $20.0K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 9,063 | $18.2K | 0.00% | −23,784−72.4% | Reduced |
| Hilton Head Capital Partners, LLC | 4,472 | $8.99K | 0.01% | +4,472 | New |
| SBI Securities Co., Ltd. | 2,574 | $5.17K | 0.00% | −8−0.3% | Reduced |
| Bank of America Corp | 2,186 | $4.39K | 0.00% | +1,803+470.8% | Added |
| National Bank of Canada | 2,014 | $4.03K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 1,900 | $3.82K | 0.00% | 00.0% | Unchanged |
| International Assets Investment Management, LLC | 521 | $1.05K | 0.00% | +521 | New |
| Royal Bank of Canada | 299 | $1.00K | 0.00% | +269+896.7% | Added |
| Citigroup Inc | 496 | $997 | 0.00% | +495+49,500.0% | Added |
| Allworth Financial LP | 5 | $11 | 0.00% | +5 | New |
| HRT Financial LP | 0 | $0 | 0.00% | −20,677−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −17,746−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −13,100−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −10,200−100.0% | Sold out |
| MAI Capital Management | 0 | $0 | 0.00% | −123−100.0% | Sold out |