Opus Genetics, Inc.
IRD- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001228627
In the last 90 days, Opus Genetics, Inc. insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $236.4M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Opus Genetics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 59
- +11 vs. Q3 2025
- Shares held
- 27.8M
- +8.78M (+46.1%) vs. Q3 2025
- Total value
- $55.9M
- +$24.0M (+75.1%) vs. Q3 2025
- New holders
- 16
- 19 more added
- Sold out
- 5
- 8 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IRD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $236.4M |
| Q1 2026 | 79 | $203.8M |
| Q4 2025 | 59 | $55.9M |
| Q3 2025 | 48 | $31.9M |
| Q2 2025 | 43 | $16.5M |
| Q1 2025 | 46 | $14.7M |
| Q4 2024 | 43 | $4.38M |
| Q3 2024 | 38 | $3.32M |
| Q2 2024 | 37 | $4.13M |
| Q1 2024 | 49 | $6.78M |
| Q4 2023 | 50 | $11.2M |
| Q3 2023 | 50 | $12.6M |
| Q2 2023 | 49 | $16.0M |
| Q1 2023 | 41 | $13.0M |
| Q4 2022 | 35 | $10.9M |
| Q3 2022 | 37 | $5.69M |
| Q2 2022 | 38 | $4.62M |
| Q1 2022 | 41 | $6.69M |
| Q4 2021 | 40 | $8.07M |
| Q3 2021 | 30 | $8.62M |
| Q2 2021 | 36 | $5.61M |
| Q1 2021 | 27 | $5.27M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Opus Genetics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Allworth Financial LP | 5 | $11 | 0.00% | +5 | New |
| Citigroup Inc | 496 | $997 | 0.00% | +495+49,500.0% | Added |
| Royal Bank of Canada | 299 | $1.00K | 0.00% | +269+896.7% | Added |
| International Assets Investment Management, LLC | 521 | $1.05K | 0.00% | +521 | New |
| Barclays PLC | 1,900 | $3.82K | 0.00% | 00.0% | Unchanged |
| National Bank of Canada | 2,014 | $4.03K | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 2,186 | $4.39K | 0.00% | +1,803+470.8% | Added |
| SBI Securities Co., Ltd. | 2,574 | $5.17K | 0.00% | −8−0.3% | Reduced |
| Hilton Head Capital Partners, LLC | 4,472 | $8.99K | 0.01% | +4,472 | New |
| Simplex Trading, LLC | 9,063 | $18.2K | 0.00% | −23,784−72.4% | Reduced |
| Annandale Capital, LLC | 10,000 | $20.0K | 0.00% | 00.0% | Unchanged |
| Reliant Investment Partners, LLC | 10,000 | $20.1K | 0.02% | 00.0% | Unchanged |
| Miller Financial Services LLC | 10,000 | $20.1K | 0.02% | +10,000 | New |
| First City Capital Management, Inc. | 11,836 | $23.8K | 0.01% | +11,836 | New |
| Comerica Bank | 12,000 | $24.1K | 0.00% | 00.0% | Unchanged |
| Stokes Family Office, LLC | 12,120 | $24.4K | 0.00% | 00.0% | Unchanged |
| Occudo Quantitative Strategies LP | 12,205 | $24.5K | 0.00% | +12,205 | New |
| Advisor Group Holdings, Inc. | 13,900 | $27.9K | 0.00% | −40.0% | Reduced |
| Bedel Financial Consulting, Inc. | 15,000 | $30.1K | 0.00% | 00.0% | Unchanged |
| Kestra Private Wealth Services, LLC | 16,000 | $32.2K | 0.00% | −3,000−15.8% | Reduced |
| James Investment Research Inc | 16,364 | $32.9K | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 16,364 | $32.9K | 0.00% | 00.0% | Unchanged |
| Virtu Financial LLC | 16,810 | $34.0K | 0.00% | +16,810 | New |
| Johnson Investment Counsel Inc | 20,000 | $40.2K | 0.00% | +20,000 | New |
| Raymond James Financial Inc | 20,508 | $41.2K | 0.00% | −2,000−8.9% | Reduced |
| XTX Topco Ltd | 23,737 | $47.7K | 0.00% | −28,020−54.1% | Reduced |
| Blair William & Co | 27,466 | $55.2K | 0.00% | +3,000+12.3% | Added |
| Morgan Stanley | 28,665 | $57.6K | 0.00% | +59+0.2% | Added |
| Captrust Financial Advisors | 32,000 | $64.3K | 0.00% | 00.0% | Unchanged |
| Qube Research & Technologies Ltd | 39,978 | $80.4K | 0.00% | +39,978 | New |
| ADAR1 Capital Management, LLC | 40,000 | $80.4K | 0.01% | +40,000 | New |
| Bridgeway Capital Management, LLC | 42,065 | $84.6K | 0.00% | 00.0% | Unchanged |
| Empowered Funds, LLC | 42,065 | $84.6K | 0.00% | 00.0% | Unchanged |
| Regency Capital Management Inc. | 46,000 | $92.5K | 0.04% | +46,000 | New |
| Texas Capital Bank Wealth Management Services Inc | 78,000 | $156.8K | 0.01% | +78,000 | New |
| Northern Trust Corp | 87,447 | $175.8K | 0.00% | +19,219+28.2% | Added |
| Omers Administration Corp | 87,900 | $176.7K | 0.00% | +87,900 | New |
| UBS Group AG | 89,818 | $180.5K | 0.00% | +88,934+10,060.4% | Added |
| Renaissance Technologies LLC | 126,309 | $253.9K | 0.00% | −47,500−27.3% | Reduced |
| Creative Planning | 128,366 | $258.0K | 0.00% | 00.0% | Unchanged |
| BlackRock, Inc. | 141,897 | $285.2K | 0.00% | +95,803+207.8% | Added |
| Two Sigma Investments, LP | 151,312 | $304.1K | 0.00% | +42,974+39.7% | Added |
| Marshall Wace, LLP | 157,648 | $316.9K | 0.00% | +157,648 | New |
| State Street Corp | 173,253 | $348.2K | 0.00% | +27,380+18.8% | Added |
| Citadel Advisors LLC | 180,721 | $363.3K | 0.00% | +67,305+59.3% | Added |
| Susquehanna International Group, LLP | 201,635 | $405.3K | 0.00% | +181,422+897.6% | Added |
| Wells Fargo & Company | 241,871 | $486.2K | 0.00% | +238,086+6,290.3% | Added |
| Voss Capital, LLC | 441,891 | $888.2K | 0.05% | −120,486−21.4% | Reduced |
| Geode Capital Management, LLC | 504,983 | $1.02M | 0.00% | +36,046+7.7% | Added |
| Bleichroeder LP | 736,842 | $1.48M | 0.26% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 1,104,996 | $2.22M | 0.00% | +150,000+15.7% | Added |
| Opaleye Management Inc. | 1,120,000 | $2.25M | 0.30% | +20,000+1.8% | Added |
| Mink Brook Asset Management LLC | 1,665,631 | $3.35M | 2.12% | +427,684+34.5% | Added |
| Millennium Management LLC | 2,002,550 | $4.03M | 0.00% | +2,002,550 | New |
| Vanguard Group Inc | 2,322,897 | $4.67M | 0.00% | +980,872+73.1% | Added |
| Balyasny Asset Management LLC | 2,718,029 | $5.46M | 0.01% | +2,718,029 | New |
| BIOS Capital Management, LP | 3,683,429 | $7.40M | 8.96% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 4,325,000 | $8.69M | 0.16% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 4,781,330 | $9.61M | 0.57% | +1,435,407+42.9% | Added |
| HRT Financial LP | 0 | $0 | 0.00% | −20,677−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −17,746−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −13,100−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −10,200−100.0% | Sold out |
| MAI Capital Management | 0 | $0 | 0.00% | −123−100.0% | Sold out |