Opus Genetics, Inc.
IRD- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001228627
In the last 90 days, Opus Genetics, Inc. insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $236.4M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Opus Genetics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 48
- +6 vs. Q2 2025
- Shares held
- 19.0M
- +1.55M (+8.9%) vs. Q2 2025
- Total value
- $31.9M
- +$15.5M (+93.9%) vs. Q2 2025
- New holders
- 10
- 12 more added
- Sold out
- 4
- 4 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IRD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $236.4M |
| Q1 2026 | 79 | $203.8M |
| Q4 2025 | 59 | $55.9M |
| Q3 2025 | 48 | $31.9M |
| Q2 2025 | 43 | $16.5M |
| Q1 2025 | 46 | $14.7M |
| Q4 2024 | 43 | $4.38M |
| Q3 2024 | 38 | $3.32M |
| Q2 2024 | 37 | $4.13M |
| Q1 2024 | 49 | $6.78M |
| Q4 2023 | 50 | $11.2M |
| Q3 2023 | 50 | $12.6M |
| Q2 2023 | 49 | $16.0M |
| Q1 2023 | 41 | $13.0M |
| Q4 2022 | 35 | $10.9M |
| Q3 2022 | 37 | $5.69M |
| Q2 2022 | 38 | $4.62M |
| Q1 2022 | 41 | $6.69M |
| Q4 2021 | 40 | $8.07M |
| Q3 2021 | 30 | $8.62M |
| Q2 2021 | 36 | $5.61M |
| Q1 2021 | 27 | $5.27M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Opus Genetics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Royal Bank of Canada | 30 | $0 | 0.00% | −127,220−100.0% | Reduced |
| Citigroup Inc | 1 | $2 | 0.00% | +1 | New |
| MAI Capital Management | 123 | $203 | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 383 | $632 | 0.00% | +98+34.4% | Added |
| UBS Group AG | 884 | $1.46K | 0.00% | −27,226−96.9% | Reduced |
| Barclays PLC | 1,900 | $3.13K | 0.00% | 00.0% | Unchanged |
| National Bank of Canada | 2,014 | $3.30K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 2,582 | $4.26K | 0.00% | −1,000−27.9% | Reduced |
| Wells Fargo & Company | 3,785 | $6.25K | 0.00% | 00.0% | Unchanged |
| Annandale Capital, LLC | 10,000 | $16.5K | 0.00% | +10,000 | New |
| Two Sigma Advisers, LP | 10,200 | $16.8K | 0.00% | +10,200 | New |
| Reliant Investment Partners, LLC | 10,000 | $18.8K | 0.01% | 00.0% | Unchanged |
| Comerica Bank | 12,000 | $19.8K | 0.00% | 00.0% | Unchanged |
| Stokes Family Office, LLC | 12,120 | $20.0K | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 13,100 | $21.6K | 0.00% | +13,100 | New |
| Advisor Group Holdings, Inc. | 13,904 | $23.7K | 0.00% | +40.0% | Added |
| Bedel Financial Consulting, Inc. | 15,000 | $24.8K | 0.00% | 00.0% | Unchanged |
| James Investment Research Inc | 16,364 | $27.0K | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 16,364 | $27.0K | 0.00% | 00.0% | Unchanged |
| Two Sigma Securities, LLC | 17,746 | $29.3K | 0.00% | +17,746 | New |
| Kestra Private Wealth Services, LLC | 19,000 | $31.4K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 20,213 | $33.4K | 0.00% | +2,910+16.8% | Added |
| HRT Financial LP | 20,677 | $34.0K | 0.00% | +20,677 | New |
| Raymond James Financial Inc | 22,508 | $37.1K | 0.00% | +11,000+95.6% | Added |
| Blair William & Co | 24,466 | $40.4K | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 28,606 | $47.2K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 32,000 | $52.8K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 32,847 | $54.0K | 0.00% | +32,847 | New |
| Bridgeway Capital Management, LLC | 42,065 | $69.4K | 0.00% | 00.0% | Unchanged |
| Empowered Funds, LLC | 42,065 | $69.4K | 0.00% | 00.0% | Unchanged |
| BlackRock, Inc. | 46,094 | $76.1K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 51,757 | $85.4K | 0.00% | +35,949+227.4% | Added |
| Northern Trust Corp | 68,228 | $112.6K | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 108,338 | $178.8K | 0.00% | +68,148+169.6% | Added |
| Citadel Advisors LLC | 113,416 | $187.1K | 0.00% | +113,416 | New |
| Creative Planning | 128,366 | $211.8K | 0.00% | +128,366 | New |
| State Street Corp | 145,873 | $240.7K | 0.00% | +75,400+107.0% | Added |
| Renaissance Technologies LLC | 173,809 | $286.8K | 0.00% | +20,500+13.4% | Added |
| Geode Capital Management, LLC | 468,937 | $773.8K | 0.00% | +113,260+31.8% | Added |
| Voss Capital, LLC | 562,377 | $927.9K | 0.05% | +21,218+3.9% | Added |
| Bleichroeder LP | 736,842 | $1.22M | 0.24% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 954,996 | $1.58M | 0.00% | +954,996 | New |
| Opaleye Management Inc. | 1,100,000 | $1.81M | 0.26% | −120,000−9.8% | Reduced |
| Mink Brook Asset Management LLC | 1,237,947 | $2.04M | 1.38% | +40,331+3.4% | Added |
| Vanguard Group Inc | 1,342,025 | $2.21M | 0.00% | +349,825+35.3% | Added |
| Nantahala Capital Management, LLC | 3,345,923 | $5.52M | 0.34% | 00.0% | Unchanged |
| BIOS Capital Management, LP | 3,683,429 | $6.59M | 7.42% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 4,325,000 | $7.14M | 0.21% | 00.0% | Unchanged |
| Millennium Management LLC | 0 | $0 | 0.00% | −127,844−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −79,346−100.0% | Sold out |
| Tower Research Capital LLC (TRC) | 0 | $0 | 0.00% | −6,698−100.0% | Sold out |
| CarsonAllaria Wealth Management, Ltd. | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| Financial Gravity Companies, Inc. | – | – | – | – | Not filed |