Opus Genetics, Inc.
IRD- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001228627
In the last 90 days, Opus Genetics, Inc. insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $236.4M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Opus Genetics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 79
- +22 vs. Q4 2025
- Shares held
- 45.4M
- +19.9M (+78.2%) vs. Q4 2025
- Total value
- $203.8M
- +$152.6M (+297.9%) vs. Q4 2025
- New holders
- 28
- 16 more added
- Sold out
- 6
- 15 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IRD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $236.4M |
| Q1 2026 | 79 | $203.8M |
| Q4 2025 | 59 | $55.9M |
| Q3 2025 | 48 | $31.9M |
| Q2 2025 | 43 | $16.5M |
| Q1 2025 | 46 | $14.7M |
| Q4 2024 | 43 | $4.38M |
| Q3 2024 | 38 | $3.32M |
| Q2 2024 | 37 | $4.13M |
| Q1 2024 | 49 | $6.78M |
| Q4 2023 | 50 | $11.2M |
| Q3 2023 | 50 | $12.6M |
| Q2 2023 | 49 | $16.0M |
| Q1 2023 | 41 | $13.0M |
| Q4 2022 | 35 | $10.9M |
| Q3 2022 | 37 | $5.69M |
| Q2 2022 | 38 | $4.62M |
| Q1 2022 | 41 | $6.69M |
| Q4 2021 | 40 | $8.07M |
| Q3 2021 | 30 | $8.62M |
| Q2 2021 | 36 | $5.61M |
| Q1 2021 | 27 | $5.27M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Opus Genetics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Royal Bank of Canada | 5 | $0 | 0.00% | −294−98.3% | Reduced |
| Allworth Financial LP | 5 | $23 | 0.00% | 00.0% | Unchanged |
| FMR LLC | 8 | $36 | 0.00% | +8 | New |
| SBI Securities Co., Ltd. | 530 | $2.41K | 0.00% | −2,044−79.4% | Reduced |
| International Assets Investment Management, LLC | 521 | $2.44K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 1,900 | $8.64K | 0.00% | 00.0% | Unchanged |
| National Bank of Canada | 2,014 | $9.14K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 2,200 | $10.0K | 0.00% | −11,700−84.2% | Reduced |
| Farther Finance Advisors, LLC | 2,300 | $10.8K | 0.00% | +2,300 | New |
| Wells Fargo & Company | 3,785 | $17.2K | 0.00% | −238,086−98.4% | Reduced |
| Hilton Head Capital Partners, LLC | 4,472 | $20.3K | 0.01% | 00.0% | Unchanged |
| Reliant Investment Partners, LLC | 10,000 | $45.5K | 0.04% | 00.0% | Unchanged |
| Annandale Capital, LLC | 10,000 | $46.0K | 0.01% | 00.0% | Unchanged |
| Group One Trading, L.P. | 10,594 | $48.2K | 0.00% | +10,594 | New |
| First City Capital Management, Inc. | 11,836 | $53.9K | 0.03% | 00.0% | Unchanged |
| Sanders Morris Harris LLC | 12,000 | $54.6K | 0.01% | +12,000 | New |
| Stokes Family Office, LLC | 12,120 | $55.1K | 0.01% | 00.0% | Unchanged |
| Blair William & Co | 12,466 | $56.7K | 0.00% | −15,000−54.6% | Reduced |
| Kestra Private Wealth Services, LLC | 12,800 | $58.2K | 0.00% | −3,200−20.0% | Reduced |
| Bedel Financial Consulting, Inc. | 15,000 | $68.3K | 0.01% | 00.0% | Unchanged |
| James Investment Research Inc | 16,364 | $74.5K | 0.01% | 00.0% | Unchanged |
| GWM Advisors LLC | 16,364 | $74.5K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 16,704 | $76.0K | 0.00% | −7,033−29.6% | Reduced |
| Persistent Asset Partners Ltd | 17,919 | $81.5K | 0.03% | +17,919 | New |
| Raymond James Financial Inc | 19,508 | $88.8K | 0.00% | −1,000−4.9% | Reduced |
| Miller Financial Services LLC | 22,000 | $100.1K | 0.11% | +12,000+120.0% | Added |
| Vanguard Global Advisers, LLC | 22,225 | $101.1K | 0.00% | +22,225 | New |
| nVerses Capital, LLC | 28,564 | $130.0K | 0.12% | +28,564 | New |
| Tower Research Capital LLC (TRC) | 28,741 | $130.8K | 0.00% | +28,741 | New |
| Captrust Financial Advisors | 32,000 | $145.6K | 0.00% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 35,000 | $159.3K | 0.00% | +35,000 | New |
| Morgan Stanley | 39,522 | $179.8K | 0.00% | +10,857+37.9% | Added |
| Omers Administration Corp | 41,600 | $189.3K | 0.00% | −46,300−52.7% | Reduced |
| Mangrove Partners | 41,717 | $189.8K | 0.02% | +41,717 | New |
| Bridgeway Capital Management, LLC | 42,065 | $191.4K | 0.00% | 00.0% | Unchanged |
| Empowered Funds, LLC | 42,065 | $191.4K | 0.00% | 00.0% | Unchanged |
| Brevan Howard Capital Management LP | 61,313 | $279.0K | 0.00% | +61,313 | New |
| Palogic Value Management, L.P. | 65,000 | $295.8K | 0.13% | +65,000 | New |
| Bank of America Corp | 67,015 | $304.9K | 0.00% | +64,829+2,965.6% | Added |
| HRT Financial LP | 67,663 | $307.0K | 0.00% | +67,663 | New |
| Regency Capital Management Inc. | 68,000 | $309.4K | 0.14% | +22,000+47.8% | Added |
| Stonepine Capital Management, LLC | 68,688 | $312.5K | 0.27% | +68,688 | New |
| Renaissance Technologies LLC | 73,209 | $333.1K | 0.00% | −53,100−42.0% | Reduced |
| Simplex Trading, LLC | 82,480 | $375.3K | 0.01% | +73,417+810.1% | Added |
| Texas Capital Bank Wealth Management Services Inc | 88,500 | $402.7K | 0.02% | +10,500+13.5% | Added |
| Northern Trust Corp | 94,415 | $429.6K | 0.00% | +6,968+8.0% | Added |
| Two Sigma Investments, LP | 108,641 | $494.3K | 0.00% | −42,671−28.2% | Reduced |
| Citadel Advisors LLC | 120,900 | $550.1K | 0.00% | −59,821−33.1% | Reduced |
| Creative Planning | 128,366 | $584.1K | 0.00% | 00.0% | Unchanged |
| Seven Fleet Capital Management LP | 134,242 | $610.8K | 0.19% | +134,242 | New |
| Voleon Capital Management LP | 143,796 | $654.3K | 0.01% | +143,796 | New |
| BlackRock, Inc. | 147,740 | $672.2K | 0.00% | +5,843+4.1% | Added |
| Jane Street Group, LLC | 158,103 | $719.4K | 0.00% | +158,103 | New |
| State Street Corp | 199,953 | $909.8K | 0.00% | +26,700+15.4% | Added |
| UBS Group AG | 257,649 | $1.17M | 0.00% | +167,831+186.9% | Added |
| Vanguard Fiduciary Trust Co | 281,801 | $1.28M | 0.00% | +281,801 | New |
| Great Point Partners LLC | 324,340 | $1.48M | 0.36% | +324,340 | New |
| Goldman Sachs Group Inc | 326,809 | $1.49M | 0.00% | +326,809 | New |
| Ameriprise Financial Inc | 388,491 | $1.77M | 0.00% | +388,491 | New |
| Opaleye Management Inc. | 1,120,000 | $2.25M | 0.30% | 00.0% | Unchanged |
| Trails Edge Capital Partners, LP | 500,000 | $2.27M | 0.54% | +500,000 | New |
| Geode Capital Management, LLC | 538,347 | $2.45M | 0.00% | +33,364+6.6% | Added |
| Mink Brook Asset Management LLC | 590,552 | $2.69M | 1.50% | −1,075,079−64.5% | Reduced |
| Bleichroeder LP | 736,842 | $3.35M | 0.58% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 823,383 | $3.75M | 0.00% | +621,748+308.4% | Added |
| Farallon Capital Management, L.L.C. | 1,000,000 | $4.55M | 0.03% | +1,000,000 | New |
| Boothbay Fund Management, LLC | 1,189,113 | $5.41M | 0.13% | +1,189,113 | New |
| Woodline Partners LP | 1,354,030 | $6.16M | 0.02% | +1,354,030 | New |
| Nantahala Capital Management, LLC | 1,681,330 | $7.65M | 0.48% | −3,100,000−64.8% | Reduced |
| Perceptive Advisors LLC | 1,835,842 | $8.35M | 0.16% | −2,489,158−57.6% | Reduced |
| ADAR1 Capital Management, LLC | 1,849,004 | $8.41M | 0.51% | +1,809,004+4,522.5% | Added |
| Boxer Capital Management, LLC | 2,250,000 | $10.2M | 1.34% | +2,250,000 | New |
| Marshall Wace, LLP | 2,313,380 | $10.5M | 0.01% | +2,155,732+1,367.4% | Added |
| Vanguard Capital Management LLC | 2,449,987 | $11.1M | 0.00% | +2,449,987 | New |
| Millennium Management LLC | 2,630,432 | $12.0M | 0.01% | +627,882+31.4% | Added |
| Balyasny Asset Management LLC | 2,718,029 | $12.4M | 0.02% | 00.0% | Unchanged |
| BIOS Capital Management, LP | 3,683,429 | $16.8M | 31.70% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 6,029,775 | $27.4M | 0.04% | +4,924,779+445.7% | Added |
| Caligan Partners LP | 6,075,028 | $27.6M | 1.96% | +6,075,028 | New |
| Voss Capital, LLC | 0 | $0 | 0.00% | −441,891−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −39,978−100.0% | Sold out |
| Johnson Investment Counsel Inc | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −16,810−100.0% | Sold out |
| Occudo Quantitative Strategies LP | 0 | $0 | 0.00% | −12,205−100.0% | Sold out |
| Citigroup Inc | 0 | $0 | 0.00% | −496−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |
| Comerica Bank | – | – | – | – | Not filed |