Iovance Biotherapeutics, Inc.
IOVA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001425205
No open-market purchases or sales by Iovance Biotherapeutics, Inc. insiders were filed in the last 90 days; 293 institutions reported holding it in 13F filings for Q2 2026, worth $1.19B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Iovance Biotherapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 263
- +15 vs. Q3 2025
- Shares held
- 261.6M
- +48.6M (+22.8%) vs. Q3 2025
- Total value
- $713.7M
- +$251.6M (+54.4%) vs. Q3 2025
- New holders
- 51
- 103 more added
- Sold out
- 36
- 63 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IOVA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 293 | $1.19B |
| Q1 2026 | 286 | $943.8M |
| Q4 2025 | 263 | $713.7M |
| Q3 2025 | 253 | $462.3M |
| Q2 2025 | 255 | $379.3M |
| Q1 2025 | 303 | $798.9M |
| Q4 2024 | 302 | $1.79B |
| Q3 2024 | 286 | $2.21B |
| Q2 2024 | 295 | $1.86B |
| Q1 2024 | 273 | $3.22B |
| Q4 2023 | 236 | $1.69B |
| Q3 2023 | 228 | $970.0M |
| Q2 2023 | 219 | $1.44B |
| Q1 2023 | 230 | $1.25B |
| Q4 2022 | 218 | $1.11B |
| Q3 2022 | 242 | $1.48B |
| Q2 2022 | 238 | $1.75B |
| Q1 2022 | 248 | $2.60B |
| Q4 2021 | 246 | $2.96B |
| Q3 2021 | 244 | $3.88B |
| Q2 2021 | 234 | $4.22B |
| Q1 2021 | 252 | $4.98B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Iovance Biotherapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Stifel Financial Corp | 329,815 | $900.4K | 0.00% | −19,780−5.7% | Reduced |
| CM Management, LLC | 400,000 | $1.09M | 0.92% | −300,000−42.9% | Reduced |
| Raymond James Financial Inc | 404,441 | $1.10M | 0.00% | +68,285+20.3% | Added |
| Hennion & Walsh Asset Management, Inc. | 410,206 | $1.12M | 0.04% | −134,147−24.6% | Reduced |
| Algert Global LLC | 433,999 | $1.18M | 0.02% | +433,999 | New |
| Raiffeisen Bank International AG | 450,000 | $1.25M | 0.02% | +210,000+87.5% | Added |
| Cresset Asset Management, LLC | 457,786 | $1.25M | 0.01% | +267,300+140.3% | Added |
| Rhumbline Advisers | 461,284 | $1.26M | 0.00% | +67,207+17.1% | Added |
| UBS Asset Management Americas Inc | 469,706 | $1.28M | 0.00% | −12,075−2.5% | Reduced |
| XTX Topco Ltd | 522,934 | $1.43M | 0.04% | +312,413+148.4% | Added |
| Brevan Howard Capital Management LP | 525,519 | $1.43M | 0.03% | +253,552+93.2% | Added |
| Qube Research & Technologies Ltd | 564,519 | $1.54M | 0.00% | +564,519 | New |
| Woodline Partners LP | 567,680 | $1.55M | 0.01% | 00.0% | Unchanged |
| Swiss National Bank | 606,456 | $1.66M | 0.00% | +88,400+17.1% | Added |
| Royal Bank of Canada | 608,459 | $1.66M | 0.00% | −946,354−60.9% | Reduced |
| LPL Financial LLC | 623,072 | $1.70M | 0.00% | +11,675+1.9% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 628,537 | $1.72M | 0.00% | +497,537+379.8% | Added |
| Voleon Capital Management LP | 630,257 | $1.72M | 0.04% | +490,288+350.3% | Added |
| Renaissance Technologies LLC | 651,000 | $1.78M | 0.00% | +651,000 | New |
| QVT Financial LP | 678,564 | $1.85M | 0.18% | 00.0% | Unchanged |
| Deutsche Bank AG | 690,416 | $1.88M | 0.00% | +44,960+7.0% | Added |
| Rafferty Asset Management, LLC | 706,450 | $1.93M | 0.01% | +223,475+46.3% | Added |
| Standard Life Aberdeen plc | 759,522 | $2.07M | 0.00% | +152,312+25.1% | Added |
| UBS Group AG | 764,154 | $2.09M | 0.00% | −172,350−18.4% | Reduced |
| Walleye Capital LLC | 822,754 | $2.25M | 0.01% | +786,077+2,143.2% | Added |
| Gsa Capital Partners LLP | 872,985 | $2.38M | 0.21% | +793,763+1,001.9% | Added |
| Susquehanna Portfolio Strategies, LLC | 914,449 | $2.50M | 0.04% | +2,350+0.3% | Added |
| Bank of New York Mellon Corp | 955,467 | $2.61M | 0.00% | +148,283+18.4% | Added |
| Mirador Capital Partners LP | 1,034,544 | $2.82M | 0.39% | +519,519+100.9% | Added |
| Barclays PLC | 1,127,157 | $3.08M | 0.00% | +190,470+20.3% | Added |
| Price T Rowe Associates Inc | 1,191,828 | $3.25M | 0.00% | −866,190−42.1% | Reduced |
| Invesco Ltd. | 1,251,665 | $3.42M | 0.00% | +306,195+32.4% | Added |
| C WorldWide Group Holding A/S | 1,260,000 | $3.44M | 0.06% | 00.0% | Unchanged |
| Nuveen, LLC | 1,385,988 | $3.78M | 0.00% | +134,507+10.7% | Added |
| Rice Hall James & Associates, LLC | 1,425,088 | $3.89M | 0.21% | −26,284−1.8% | Reduced |
| B Group, Inc. | 1,500,000 | $4.09M | 3.03% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 1,539,110 | $4.20M | 0.00% | −1,283,648−45.5% | Reduced |
| Rhenman & Partners Asset Management AB | 1,595,327 | $4.36M | 0.41% | +497,500+45.3% | Added |
| Orion Investment Co | 1,856,934 | $5.07M | 1.55% | +5,150+0.3% | Added |
| Wells Fargo & Company | 1,993,337 | $5.44M | 0.00% | +475,973+31.4% | Added |
| Northern Trust Corp | 2,579,594 | $7.04M | 0.00% | +118,521+4.8% | Added |
| Charles Schwab Investment Management Inc | 2,753,343 | $7.52M | 0.00% | +248,801+9.9% | Added |
| JPMorgan Chase & Co | 3,001,502 | $8.19M | 0.00% | +1,777,671+145.3% | Added |
| Two Sigma Advisers, LP | 3,015,000 | $8.23M | 0.02% | +1,956,000+184.7% | Added |
| Citadel Advisors LLC | 3,143,091 | $8.58M | 0.01% | −677,273−17.7% | Reduced |
| Jane Street Group, LLC | 3,583,810 | $9.78M | 0.01% | +2,170,148+153.5% | Added |
| D. E. Shaw & Co., Inc. | 3,829,795 | $10.5M | 0.01% | +3,753,586+4,925.4% | Added |
| HRT Financial LP | 4,356,010 | $11.9M | 0.04% | +3,986,314+1,078.3% | Added |
| Two Sigma Investments, LP | 4,397,989 | $12.0M | 0.02% | +1,657,135+60.5% | Added |
| Susquehanna International Group, LLP | 4,948,614 | $13.5M | 0.02% | +1,642,098+49.7% | Added |
| Millennium Management LLC | 6,585,532 | $18.0M | 0.01% | +2,172,081+49.2% | Added |
| Palo Alto Investors LP | 7,116,676 | $19.4M | 2.70% | −501,456−6.6% | Reduced |
| Geode Capital Management, LLC | 7,991,640 | $21.8M | 0.00% | +1,123,337+16.4% | Added |
| Long Focus Capital Management, LLC | 8,600,000 | $23.5M | 1.17% | −516,507−5.7% | Reduced |
| Goldman Sachs Group Inc | 8,607,564 | $23.5M | 0.00% | +2,032,062+30.9% | Added |
| Morgan Stanley | 9,191,840 | $25.1M | 0.00% | +3,610,277+64.7% | Added |
| Invenomic Capital Management LP | 11,959,505 | $32.6M | 1.58% | +1,417,897+13.5% | Added |
| Bank of America Corp | 14,277,813 | $39.0M | 0.00% | +7,998,583+127.4% | Added |
| State Street Corp | 20,161,445 | $55.0M | 0.00% | +6,851,486+51.5% | Added |
| Vanguard Group Inc | 27,207,079 | $74.3M | 0.00% | +3,148,096+13.1% | Added |
| MHR Fund Management LLC | 28,967,103 | $79.1M | 6.81% | 00.0% | Unchanged |
| BlackRock, Inc. | 29,518,125 | $80.6M | 0.00% | +3,561,836+13.7% | Added |
| DekaBank Deutsche Girozentrale | 100,000 | – | – | 00.0% | Unchanged |
| Soleus Capital Management, L.P. | 0 | $0 | 0.00% | −976,707−100.0% | Sold out |
| Voss Capital, LLC | 0 | $0 | 0.00% | −650,000−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −543,760−100.0% | Sold out |
| Cinctive Capital Management LP | 0 | $0 | 0.00% | −195,290−100.0% | Sold out |
| NEOS Investment Management LLC | 0 | $0 | 0.00% | −173,872−100.0% | Sold out |
| Tema ETFs LLC | 0 | $0 | 0.00% | −173,872−100.0% | Sold out |
| DnB Asset Management AS | 0 | $0 | 0.00% | −124,045−100.0% | Sold out |
| Atom Investors LP | 0 | $0 | 0.00% | −113,921−100.0% | Sold out |
| Guggenheim Capital LLC | 0 | $0 | 0.00% | −110,380−100.0% | Sold out |
| Handelsbanken Fonder AB | 0 | $0 | 0.00% | −96,900−100.0% | Sold out |
| Polymer Capital Management (US) LLC | 0 | $0 | 0.00% | −75,803−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −38,515−100.0% | Sold out |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −40,445−100.0% | Sold out |
| Arete Wealth Advisors, LLC | 0 | $0 | 0.00% | −24,250−100.0% | Sold out |
| Mariner, LLC | 0 | $0 | 0.00% | −22,291−100.0% | Sold out |
| Saturna Capital CORP | 0 | $0 | 0.00% | −20,553−100.0% | Sold out |
| Natixis | 0 | $0 | 0.00% | −20,479−100.0% | Sold out |
| Arkadios Wealth Advisors | 0 | $0 | 0.00% | −20,100−100.0% | Sold out |
| HB Wealth Management, LLC | 0 | $0 | 0.00% | −19,297−100.0% | Sold out |
| Stoneridge Investment Partners LLC | 0 | $0 | 0.00% | −16,993−100.0% | Sold out |
| Wealthfront Advisers LLC | 0 | $0 | 0.00% | −15,492−100.0% | Sold out |
| Meeder Advisory Services, Inc. | 0 | $0 | 0.00% | −14,537−100.0% | Sold out |
| T. Rowe Price Investment Management, Inc. | 0 | $0 | 0.00% | −12,638−100.0% | Sold out |
| Vontobel Holding Ltd. | 0 | $0 | 0.00% | −12,067−100.0% | Sold out |
| Pine Valley Investments Ltd Liability Co | 0 | $0 | 0.00% | −11,078−100.0% | Sold out |
| Ground Swell Capital, LLC | 0 | $0 | 0.00% | −11,044−100.0% | Sold out |
| SummitTX Capital, L.P. | 0 | $0 | 0.00% | −10,300−100.0% | Sold out |
| Sanders Morris Harris LLC | 0 | $0 | 0.00% | −10,250−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Wealthspire Advisors, LLC | 0 | $0 | 0.00% | −5,545−100.0% | Sold out |
| Hopwood Financial Services, Inc. | 0 | $0 | 0.00% | −2,000−100.0% | Sold out |
| Mountain Hill Investment Partners Corp. | 0 | $0 | 0.00% | −1,100−100.0% | Sold out |
| Ameritas Advisory Services, LLC | 0 | $0 | 0.00% | −577−100.0% | Sold out |
| Quent Capital, LLC | 0 | $0 | 0.00% | −83−100.0% | Sold out |
| AdvisorNet Financial, Inc | 0 | $0 | 0.00% | −74−100.0% | Sold out |
| Global Retirement Partners, LLC | 0 | $0 | 0.00% | −5−100.0% | Sold out |
| CIBC Bancorp USA Inc. | – | – | – | – | Not filed |