Heron Therapeutics, Inc.
HRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000818033
No open-market purchases or sales by Heron Therapeutics, Inc. insiders were filed in the last 90 days; 163 institutions reported holding it in 13F filings for Q2 2026, worth $57.1M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Heron Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 170
- 0 vs. Q3 2025
- Shares held
- 156.5M
- +3.93M (+2.6%) vs. Q3 2025
- Total value
- $203.2M
- +$11.0M (+5.7%) vs. Q3 2025
- New holders
- 25
- 56 more added
- Sold out
- 25
- 44 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting HRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 163 | $57.1M |
| Q1 2026 | 167 | $125.6M |
| Q4 2025 | 170 | $203.2M |
| Q3 2025 | 172 | $192.4M |
| Q2 2025 | 171 | $272.1M |
| Q1 2025 | 165 | $274.5M |
| Q4 2024 | 161 | $175.8M |
| Q3 2024 | 173 | $242.4M |
| Q2 2024 | 190 | $453.7M |
| Q1 2024 | 161 | $330.5M |
| Q4 2023 | 151 | $191.2M |
| Q3 2023 | 141 | $121.9M |
| Q2 2023 | 149 | $114.7M |
| Q1 2023 | 162 | $163.1M |
| Q4 2022 | 176 | $289.5M |
| Q3 2022 | 186 | $514.2M |
| Q2 2022 | 174 | $321.6M |
| Q1 2022 | 186 | $620.5M |
| Q4 2021 | 200 | $1.07B |
| Q3 2021 | 197 | $1.16B |
| Q2 2021 | 189 | $1.61B |
| Q1 2021 | 193 | $1.48B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Heron Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Redwood Family Wealth LLC | 64,500 | $83.8K | 0.08% | +64,500 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 71,369 | $92.8K | 0.00% | −491−0.7% | Reduced |
| Price T Rowe Associates Inc | 76,638 | $100.0K | 0.00% | 00.0% | Unchanged |
| Glenmede Trust Co NA | 82,189 | $106.8K | 0.00% | +82,189 | New |
| FMR LLC | 84,197 | $109.5K | 0.00% | +36,803+77.7% | Added |
| Searle & Co. | 86,250 | $112.1K | 0.03% | 00.0% | Unchanged |
| MetLife Investment Management | 87,754 | $114.1K | 0.00% | −4,672−5.1% | Reduced |
| Deutsche Bank AG | 93,081 | $121.0K | 0.00% | +7,923+9.3% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 94,009 | $122.2K | 0.00% | +10,314+12.3% | Added |
| Integrated Wealth Concepts LLC | 95,174 | $123.7K | 0.00% | −2,421−2.5% | Reduced |
| Biltmore Family Office, LLC | 100,000 | $130.0K | 0.02% | 00.0% | Unchanged |
| Simplex Trading, LLC | 114,604 | $149.0K | 0.00% | +87,734+326.5% | Added |
| Raymond James Financial Inc | 120,199 | $156.3K | 0.00% | +8,527+7.6% | Added |
| Bank of America Corp | 134,445 | $174.8K | 0.00% | −597,628−81.6% | Reduced |
| Gsa Capital Partners LLP | 135,089 | $176.0K | 0.02% | +34,908+34.8% | Added |
| Capital Planning Advisors, LLC | 144,095 | $187.3K | 0.03% | 00.0% | Unchanged |
| Group One Trading, L.P. | 145,167 | $188.7K | 0.01% | +145,167 | New |
| Quinn Opportunity Partners LLC | 175,344 | $227.9K | 0.01% | 00.0% | Unchanged |
| Wells Fargo & Company | 179,620 | $233.5K | 0.00% | +56,488+45.9% | Added |
| Alliancebernstein L.P. | 198,550 | $258.1K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 203,319 | $264.3K | 0.00% | −21,334−9.5% | Reduced |
| Los Angeles Capital Management LLC | 248,567 | $283.4K | 0.00% | +2,154+0.9% | Added |
| Quadrature Capital Ltd | 227,784 | $296.1K | 0.00% | +227,784 | New |
| XTX Topco Ltd | 240,197 | $312.3K | 0.01% | +209,700+687.6% | Added |
| Bridgeway Capital Management, LLC | 242,000 | $314.6K | 0.01% | −458,000−65.4% | Reduced |
| Cyndeo Wealth Partners, LLC | 248,087 | $322.5K | 0.02% | 00.0% | Unchanged |
| Palumbo Wealth Management LLC | 259,413 | $337.2K | 0.08% | +42,907+19.8% | Added |
| Apeiron RIA LLC | 259,968 | $358.8K | 0.07% | +37,090+16.6% | Added |
| Barclays PLC | 303,209 | $394.2K | 0.00% | +23,852+8.5% | Added |
| Invesco Ltd. | 307,861 | $400.2K | 0.00% | +76,466+33.0% | Added |
| Susquehanna International Group, LLP | 340,246 | $442.3K | 0.00% | +11,279+3.4% | Added |
| Nuveen, LLC | 347,065 | $451.2K | 0.00% | 00.0% | Unchanged |
| AQR Capital Management LLC | 376,300 | $489.2K | 0.00% | −1,560,389−80.6% | Reduced |
| Bank of New York Mellon Corp | 418,477 | $544.0K | 0.00% | +6,003+1.5% | Added |
| Panagora Asset Management Inc | 440,252 | $572.3K | 0.00% | +440,252 | New |
| Highland Capital Management Fund Advisors, L.P. | 475,750 | $618.5K | 0.04% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 519,571 | $675.4K | 0.00% | +337,500+185.4% | Added |
| Richmond Brothers, Inc. | 572,118 | $743.8K | 0.47% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 677,947 | $881.3K | 0.00% | +462,840+215.2% | Added |
| Orchard Capital Managment, LLC | 680,432 | $884.6K | 0.77% | +3,142+0.5% | Added |
| CM Management, LLC | 750,000 | $975.0K | 0.82% | 00.0% | Unchanged |
| Morgan Stanley | 963,851 | $1.25M | 0.00% | −1,504,190−60.9% | Reduced |
| Goldman Sachs Group Inc | 989,796 | $1.29M | 0.00% | −335,006−25.3% | Reduced |
| Two Sigma Investments, LP | 999,509 | $1.30M | 0.00% | +307,230+44.4% | Added |
| Northern Trust Corp | 1,091,411 | $1.42M | 0.00% | −66,162−5.7% | Reduced |
| Monaco Asset Management SAM | 1,233,022 | $1.60M | 0.48% | +230,546+23.0% | Added |
| Stonepine Capital Management, LLC | 1,237,802 | $1.61M | 1.27% | +387,702+45.6% | Added |
| Jane Street Group, LLC | 1,367,891 | $1.78M | 0.00% | +1,147,583+520.9% | Added |
| Charles Schwab Investment Management Inc | 1,415,336 | $1.84M | 0.00% | +138,295+10.8% | Added |
| Pale Fire Capital SE | 1,469,655 | $1.91M | 0.25% | +998,465+211.9% | Added |
| Renaissance Technologies LLC | 1,915,900 | $2.49M | 0.00% | −939,099−32.9% | Reduced |
| UBS Group AG | 2,091,669 | $2.72M | 0.00% | −842,412−28.7% | Reduced |
| Citadel Advisors LLC | 2,095,045 | $2.72M | 0.00% | −613,412−22.6% | Reduced |
| New York State Common Retirement Fund | 2,576,716 | $3.35M | 0.00% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 3,004,640 | $3.91M | 0.00% | −83,852−2.7% | Reduced |
| Congress Park Capital LLC | 3,067,475 | $3.99M | 1.19% | +177,318+6.1% | Added |
| JW Asset Management, LLC | 3,671,073 | $4.77M | 1.55% | +378,440+11.5% | Added |
| State Street Corp | 3,778,043 | $4.91M | 0.00% | +126,540+3.5% | Added |
| Geode Capital Management, LLC | 4,081,222 | $5.31M | 0.00% | +438,240+12.0% | Added |
| Tejara Capital Ltd | 5,131,426 | $6.67M | 2.77% | +541,711+11.8% | Added |
| Tang Capital Management LLC | 6,250,000 | $8.13M | 0.40% | +2,800,000+81.2% | Added |
| Palisade Capital Management LLC | 6,326,113 | $8.22M | 0.24% | −1,001,334−13.7% | Reduced |
| Millennium Management LLC | 7,169,908 | $9.32M | 0.01% | +6,921,405+2,785.2% | Added |
| Velan Capital Investment Management LP | 8,753,290 | $11.4M | 6.62% | 00.0% | Unchanged |
| Vanguard Group Inc | 9,820,384 | $12.8M | 0.00% | +1,360,600+16.1% | Added |
| BlackRock, Inc. | 10,218,236 | $13.3M | 0.00% | +230,776+2.3% | Added |
| Adage Capital Partners GP, L.L.C. | 11,185,325 | $14.5M | 0.02% | +946,100+9.2% | Added |
| Clearline Capital LP | 12,235,239 | $15.9M | 1.20% | +2,522,712+26.0% | Added |
| Rubric Capital Management LP | 30,046,828 | $39.1M | 0.47% | +946,100+3.3% | Added |
| Colony Group, LLC | 148,470 | – | – | +129,855+697.6% | Added |
| Baker Bros. Advisors LP | 0 | $0 | 0.00% | −4,251,951−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −1,308,861−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −734,297−100.0% | Sold out |
| Wellington Management Group LLP | 0 | $0 | 0.00% | −525,774−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −99,335−100.0% | Sold out |
| Motiv8 Investments LLC | 0 | $0 | 0.00% | −69,245−100.0% | Sold out |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −67,592−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −34,465−100.0% | Sold out |
| Wealth Alliance | 0 | $0 | 0.00% | −32,000−100.0% | Sold out |
| GWM Advisors LLC | 0 | $0 | 0.00% | −28,187−100.0% | Sold out |
| Voleon Capital Management LP | 0 | $0 | 0.00% | −26,940−100.0% | Sold out |
| Wealth Enhancement Advisory Services, LLC | 0 | $0 | 0.00% | −25,577−100.0% | Sold out |
| PKS Advisory Services, LLC | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −16,928−100.0% | Sold out |
| Bank of Montreal | 0 | $0 | 0.00% | −15,495−100.0% | Sold out |
| R Squared Ltd | 0 | $0 | 0.00% | −15,219−100.0% | Sold out |
| Envestnet Asset Management Inc | 0 | $0 | 0.00% | −14,780−100.0% | Sold out |
| AE Wealth Management LLC | 0 | $0 | 0.00% | −14,651−100.0% | Sold out |
| D.A. Davidson & Co. | 0 | $0 | 0.00% | −13,500−100.0% | Sold out |
| Creative Planning | 0 | $0 | 0.00% | −12,409−100.0% | Sold out |
| Principal Financial Group Inc | 0 | $0 | 0.00% | −11,654−100.0% | Sold out |
| Gleason Group, Inc. | 0 | $0 | 0.00% | −6,670−100.0% | Sold out |
| Future Financial Wealth Managment LLC | 0 | $0 | 0.00% | −3,500−100.0% | Sold out |
| Financial Consulate, Inc | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| CNB Bank | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| Glenmede Investment Management, LP | – | – | – | – | Not filed |
| CIBC Bancorp USA Inc. | – | – | – | – | Not filed |