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Gyre Therapeutics, Inc.

GYRE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001124105

No open-market purchases or sales by Gyre Therapeutics, Inc. insiders were filed in the last 90 days; 59 institutions reported holding it in 13F filings for Q2 2026, worth $57.1M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Gyre Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
56
+13 vs. Q4 2025
Shares held
3.41M
+1.26M (+59.0%) vs. Q4 2025
Total value
$23.8M
+$8.62M (+57.0%) vs. Q4 2025
New holders
15
18 more added
Sold out
2
11 more reduced

1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GYRE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 56 institutions
Q1 2021: 89 institutionsQ2 2021: 69 institutionsQ3 2021: 66 institutionsQ4 2021: 51 institutionsQ1 2022: 43 institutionsQ2 2022: 41 institutionsQ3 2022: 35 institutionsQ4 2022: 35 institutionsQ1 2023: 40 institutionsQ2 2023: 29 institutionsQ3 2023: 32 institutionsQ4 2023: 16 institutionsQ1 2024: 21 institutionsQ2 2024: 30 institutionsQ3 2024: 37 institutionsQ4 2024: 41 institutionsQ1 2025: 46 institutionsQ2 2025: 48 institutionsQ3 2025: 48 institutionsQ4 2025: 44 institutionsQ1 2026: 56 institutionsQ2 2026: 59 institutions
Value heldQ1 2026: $23.8M
Q1 2021: $113.0MQ2 2021: $87.7MQ3 2021: $75.7MQ4 2021: $13.7MQ1 2022: $6.39MQ2 2022: $14.2MQ3 2022: $3.90MQ4 2022: $2.63MQ1 2023: $707.6KQ2 2023: $796.3KQ3 2023: $1.04MQ4 2023: $15.6MQ1 2024: $14.3MQ2 2024: $15.0MQ3 2024: $20.2MQ4 2024: $21.6MQ1 2025: $20.1MQ2 2025: $25.1MQ3 2025: $23.1MQ4 2025: $23.6MQ1 2026: $23.8MQ2 2026: $57.1M
Institutions holding GYRE and their total value by quarter
QuarterHoldersValue
Q2 202659$57.1M
Q1 202656$23.8M
Q4 202544$23.6M
Q3 202548$23.1M
Q2 202548$25.1M
Q1 202546$20.1M
Q4 202441$21.6M
Q3 202437$20.2M
Q2 202430$15.0M
Q1 202421$14.3M
Q4 202316$15.6M
Q3 202332$1.04M
Q2 202329$796.3K
Q1 202340$707.6K
Q4 202235$2.63M
Q3 202235$3.90M
Q2 202241$14.2M
Q1 202243$6.39M
Q4 202151$13.7M
Q3 202166$75.7M
Q2 202169$87.7M
Q1 202189$113.0M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Gyre Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding GYRE in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd14$00.00%+8+133.3%Added
EverSource Wealth Advisors, LLC3$210.00%+3New
Caitong International Asset Management Co., Ltd3$210.00%+3New
MAI Capital Management4$280.00%+4New
Essential Partners LLC4$280.00%+4New
Smartleaf Asset Management LLC6$410.00%00.0%Unchanged
Massmutual Trust Co FSB12$840.00%+12New
Advisor Group Holdings, Inc.38$2650.00%00.0%Unchanged
GoalVest Advisory LLC50$3490.00%+50New
Sterling Capital Management LLC59$4110.00%00.0%Unchanged
Advisory Services Network, LLC66$4600.00%+66New
GAMMA Investing LLC82$5720.00%+82New
US Bancorp98$6830.00%+98New
Optiver Holding B.V.102$7110.00%−120−54.1%Reduced
Nisa Investment Advisors, LLC102$7110.00%00.0%Unchanged
CWM, LLC104$7250.00%+68+188.9%Added
Activest Wealth Management533$3.71K0.00%00.0%Unchanged
Citigroup Inc629$4.38K0.00%+361+134.7%Added
California State Teachers Retirement System639$4.45K0.00%−87−12.0%Reduced
Simplex Trading, LLC674$4.70K0.00%−165−19.7%Reduced
Ameritas Investment Partners, Inc.683$4.76K0.00%00.0%Unchanged
Allworth Financial LP721$5.03K0.00%+721New
Russell Investments Group, Ltd.1,124$7.83K0.00%−879−43.9%Reduced
Legal & General Group Plc1,251$8.71K0.00%−154−11.0%Reduced
Police & Firemen's Retirement System of New Jersey2,097$14.6K0.00%00.0%Unchanged
Barclays PLC2,300$16.0K0.00%−16,231−87.6%Reduced
BNP Paribas Arbitrage, SA2,571$17.9K0.00%+20+0.8%Added
New York State Common Retirement Fund2,700$18.8K0.00%00.0%Unchanged
Wells Fargo & Company4,290$29.9K0.00%−8,629−66.8%Reduced
JPMorgan Chase & Co5,181$35.4K0.00%+68+1.3%Added
State of Alaska, Department of Revenue5,219$36.0K0.00%00.0%Unchanged
Royal Bank of Canada5,605$39.0K0.00%−7,160−56.1%Reduced
Mirae Asset Global ETFs Holdings Ltd.5,617$39.1K0.00%+136+2.5%Added
Tower Research Capital LLC (TRC)5,763$40.2K0.00%+3,686+177.5%Added
Morgan Stanley8,641$60.2K0.00%−45,857−84.1%Reduced
Vanguard Global Advisers, LLC9,983$69.6K0.00%+9,983New
Bank of America Corp10,538$73.5K0.00%+779+8.0%Added
Deutsche Bank AG10,613$74.0K0.00%00.0%Unchanged
Rhumbline Advisers13,116$91.4K0.00%−916−6.5%Reduced
Brevan Howard Capital Management LP13,808$96.2K0.00%+13,808New
FMR LLC18,717$130.5K0.00%+8,413+81.6%Added
UBS Group AG21,087$147.0K0.00%+11,503+120.0%Added
STRS Ohio21,100$147.1K0.00%00.0%Unchanged
Alliancebernstein L.P.21,830$154.1K0.00%00.0%Unchanged
Dimensional Fund Advisors LP25,268$176.1K0.00%+14,365+131.8%Added
Bank of New York Mellon Corp43,144$300.7K0.00%+1,941+4.7%Added
Vanguard Portfolio Management LLC69,814$486.6K0.00%+69,814New
Goldman Sachs Group Inc73,122$509.7K0.00%+42,014+135.1%Added
Northern Trust Corp133,841$932.9K0.00%+4,986+3.9%Added
Vanguard Fiduciary Trust Co137,682$959.6K0.00%+137,682New
Charles Schwab Investment Management Inc165,238$1.15M0.00%−3,920−2.3%Reduced
SBI Securities Co., Ltd.170,837$1.19M0.03%+7,922+4.9%Added
State Street Corp216,326$1.51M0.00%+14,101+7.0%Added
Geode Capital Management, LLC431,414$3.01M0.00%+8,192+1.9%Added
BlackRock, Inc.758,630$5.29M0.00%+38,339+5.3%Added
Vanguard Capital Management LLC984,204$6.86M0.00%+984,204New
State of Wisconsin Investment Board0$00.00%−24,800−100.0%Sold out
Amalgamated Bank0$00.00%−371−100.0%Sold out
Vanguard Group Inc––––Not filed