CRISPR Therapeutics AG
CRSP- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001674416
In the last 90 days, CRISPR Therapeutics AG insiders filed 0 open-market purchases and 2 sales; 525 institutions reported holding it in 13F filings for Q2 2026, worth $4.16B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in CRISPR Therapeutics AG as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 482
- +44 vs. Q3 2025
- Shares held
- 76.5M
- +4.26M (+5.9%) vs. Q3 2025
- Total value
- $4.01B
- −$669.3M (−14.3%) vs. Q3 2025
- New holders
- 96
- 149 more added
- Sold out
- 52
- 129 more reduced
4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CRSP on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 525 | $4.16B |
| Q1 2026 | 494 | $3.67B |
| Q4 2025 | 482 | $4.01B |
| Q3 2025 | 442 | $4.68B |
| Q2 2025 | 435 | $3.52B |
| Q1 2025 | 398 | $2.20B |
| Q4 2024 | 406 | $2.54B |
| Q3 2024 | 417 | $2.81B |
| Q2 2024 | 450 | $3.22B |
| Q1 2024 | 483 | $4.10B |
| Q4 2023 | 472 | $3.48B |
| Q3 2023 | 410 | $2.50B |
| Q2 2023 | 420 | $3.07B |
| Q1 2023 | 383 | $2.54B |
| Q4 2022 | 399 | $2.26B |
| Q3 2022 | 436 | $3.70B |
| Q2 2022 | 437 | $3.35B |
| Q1 2022 | 446 | $3.10B |
| Q4 2021 | 448 | $3.25B |
| Q3 2021 | 477 | $4.53B |
| Q2 2021 | 501 | $6.57B |
| Q1 2021 | 446 | $5.20B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding CRISPR Therapeutics AG; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| ARK Investment Management LLCSuperinvestorARK Invest | 10,522,057 | $551.8M | 3.66% | +735,084+7.5% | Added |
| BlackRock, Inc. | 7,508,178 | $393.7M | 0.01% | +458,033+6.5% | Added |
| Orbis Allan Gray Ltd | 5,950,145 | $312.0M | 1.31% | +968,060+19.4% | Added |
| Capital International Investors | 5,892,745 | $309.0M | 0.05% | +243,487+4.3% | Added |
| State Street Corp | 3,753,440 | $196.8M | 0.01% | −253,793−6.3% | Reduced |
| T. Rowe Price Investment Management, Inc. | 3,226,595 | $169.2M | 0.11% | −55,989−1.7% | Reduced |
| GSK plc | 3,220,627 | $168.9M | 21.14% | +3,220,627 | New |
| UBS Group AG | 2,524,144 | $132.4M | 0.03% | +185,088+7.9% | Added |
| Vanguard Group Inc | 2,268,394 | $119.0M | 0.00% | −96,251−4.1% | Reduced |
| Geode Capital Management, LLC | 2,249,223 | $118.0M | 0.01% | +108,053+5.0% | Added |
| Sr One Capital Management, LP | 2,038,763 | $106.9M | 15.14% | 00.0% | Unchanged |
| Sumitomo Mitsui Trust Holdings, Inc. | 1,958,111 | $102.7M | 0.06% | −205,564−9.5% | Reduced |
| Nikko Asset Management Americas, Inc. | 1,958,111 | $102.6M | 1.19% | −205,564−9.5% | Reduced |
| FMR LLC | 1,953,957 | $102.5M | 0.01% | +68,294+3.6% | Added |
| EcoR1 Capital, LLC | 1,389,276 | $72.9M | 3.34% | 00.0% | Unchanged |
| Bank of America Corp | 1,096,887 | $57.5M | 0.00% | −27,232−2.4% | Reduced |
| NEA Management Company, LLC | 1,058,570 | $55.5M | 2.83% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 1,030,182 | $54.0M | 0.01% | +44,412+4.5% | Added |
| Dimensional Fund Advisors LP | 907,107 | $47.6M | 0.01% | +30,078+3.4% | Added |
| Loomis Sayles & Co L P | 899,331 | $47.2M | 0.06% | −10,383−1.1% | Reduced |
| Susquehanna International Group, LLP | 853,971 | $44.8M | 0.06% | +39,647+4.9% | Added |
| Northern Trust Corp | 755,105 | $39.6M | 0.01% | −24,825−3.2% | Reduced |
| Morgan Stanley | 667,060 | $35.0M | 0.00% | −730,799−52.3% | Reduced |
| Squarepoint Ops LLC | 581,108 | $30.5M | 0.06% | +581,108 | New |
| JPMorgan Chase & Co | 542,954 | $28.5M | 0.00% | −50,462−8.5% | Reduced |
| Norges Bank | 490,206 | $25.7M | 0.00% | +490,206 | New |
| Two Sigma Investments, LP | 470,621 | $24.7M | 0.04% | −574,068−55.0% | Reduced |
| Davy Global Fund Management Ltd | 389,519 | $20.4M | 1.41% | +106,408+37.6% | Added |
| Wells Fargo & Company | 318,878 | $16.7M | 0.00% | +15,700+5.2% | Added |
| Bank of New York Mellon Corp | 310,954 | $16.3M | 0.00% | +6,347+2.1% | Added |
| Ameriprise Financial Inc | 297,244 | $15.6M | 0.00% | −14,619−4.7% | Reduced |
| Goldman Sachs Group Inc | 275,632 | $14.5M | 0.00% | +42,090+18.0% | Added |
| Citadel Advisors LLC | 267,685 | $14.0M | 0.01% | +100,584+60.2% | Added |
| Barclays PLC | 249,988 | $13.1M | 0.01% | −99,863−28.5% | Reduced |
| Vestmark Advisory Solutions, Inc. | 249,548 | $13.1M | 0.18% | +10,586+4.4% | Added |
| Nuveen, LLC | 183,384 | $9.62M | 0.00% | +543+0.3% | Added |
| Pictet Asset Management Holding SA | 167,464 | $9.02M | 0.01% | −25,129−13.0% | Reduced |
| LPL Financial LLC | 170,831 | $8.96M | 0.00% | −40,230−19.1% | Reduced |
| Raymond James Financial Inc | 167,148 | $8.77M | 0.00% | +57,318+52.2% | Added |
| Royal Bank of Canada | 165,565 | $8.68M | 0.00% | −300,605−64.5% | Reduced |
| Two Sigma Advisers, LP | 162,400 | $8.52M | 0.02% | −410,572−71.7% | Reduced |
| Swiss National Bank | 161,500 | $8.47M | 0.01% | +2,400+1.5% | Added |
| TD Asset Management Inc | 158,416 | $8.31M | 0.01% | −16,200−9.3% | Reduced |
| Contrarius Group Holdings Ltd | 156,605 | $8.21M | 0.40% | −113,745−42.1% | Reduced |
| UBS Asset Management Americas Inc | 148,901 | $7.81M | 0.00% | +148,901 | New |
| Versant Venture Management, LLC | 148,831 | $7.80M | 5.17% | 00.0% | Unchanged |
| Citigroup Inc | 132,693 | $6.96M | 0.00% | +72,204+119.4% | Added |
| Marex Group plc | 127,546 | $6.69M | 0.07% | +3,777+3.1% | Added |
| No Street GP LP | 125,000 | $6.55M | 0.44% | +125,000 | New |
| Rhumbline Advisers | 118,778 | $6.23M | 0.01% | −5,129−4.1% | Reduced |
| Reynders McVeigh Capital Management, LLC | 116,514 | $6.11M | 0.29% | +3,514+3.1% | Added |
| California Public Employees Retirement System | 116,104 | $6.09M | 0.00% | +6,732+6.2% | Added |
| Rockefeller Capital Management L.P. | 112,667 | $5.91M | 0.01% | −35,864−24.1% | Reduced |
| Private Advisor Group, LLC | 107,259 | $5.62M | 0.03% | −10,854−9.2% | Reduced |
| Algert Global LLC | 102,850 | $5.39M | 0.08% | +102,850 | New |
| Rafferty Asset Management, LLC | 101,014 | $5.30M | 0.02% | −53,281−34.5% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 89,356 | $5.20M | 0.01% | +5,340+6.4% | Added |
| Beck Bode, LLC | 98,801 | $5.18M | 0.86% | +98,801 | New |
| Alliancebernstein L.P. | 96,357 | $5.05M | 0.00% | +10,023+11.6% | Added |
| Capital International Sarl | 94,769 | $4.97M | 0.08% | −4,888−4.9% | Reduced |
| Baker Chad R | 93,270 | $4.96M | 0.89% | +65+0.1% | Added |
| Group One Trading, L.P. | 93,954 | $4.93M | 0.15% | −3,288−3.4% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 89,708 | $4.71M | 0.01% | −9,496−9.6% | Reduced |
| Legal & General Group Plc | 87,911 | $4.61M | 0.00% | −4,568−4.9% | Reduced |
| Van Eck Associates Corp | 85,831 | $4.50M | 0.00% | +2,187+2.6% | Added |
| Price T Rowe Associates Inc | 84,940 | $4.46M | 0.00% | +8,405+11.0% | Added |
| Himension Fund | 84,390 | $4.43M | 0.27% | +12,051+16.7% | Added |
| Neo Ivy Capital Management | 78,726 | $4.13M | 0.65% | +78,726 | New |
| California State Teachers Retirement System | 78,123 | $4.10M | 0.00% | +3,212+4.3% | Added |
| Commonwealth Equity Services, LLC | 78,113 | $4.10M | 0.01% | +9,016+13.0% | Added |
| Slow Capital, Inc. | 76,630 | $4.02M | 0.48% | +3,343+4.6% | Added |
| Deutsche Bank AG | 70,492 | $3.70M | 0.00% | +5,690+8.8% | Added |
| Nwam LLC | 61,843 | $3.38M | 0.19% | −39,926−39.2% | Reduced |
| Cetera Investment Advisers | 63,913 | $3.35M | 0.00% | +83+0.1% | Added |
| Congress Asset Management Co | 63,336 | $3.32M | 0.02% | −4,774−7.0% | Reduced |
| Invesco Ltd. | 60,796 | $3.19M | 0.00% | −4,531−6.9% | Reduced |
| Advisor Group Holdings, Inc. | 59,211 | $3.10M | 0.00% | +3,276+5.9% | Added |
| Jones Financial Companies LLLP | 57,489 | $3.01M | 0.00% | +12,774+28.6% | Added |
| EverSource Wealth Advisors, LLC | 57,465 | $3.01M | 0.11% | −39,969−41.0% | Reduced |
| Guggenheim Capital LLC | 57,021 | $2.99M | 0.02% | −440−0.8% | Reduced |
| Envestnet Asset Management Inc | 56,572 | $2.97M | 0.00% | −13,817−19.6% | Reduced |
| Green Alpha Advisors, LLC | 55,737 | $2.92M | 2.68% | +725+1.3% | Added |
| Capital International Ltd | 55,519 | $2.91M | 0.10% | −6,033−9.8% | Reduced |
| Benjamin Edwards Inc | 54,636 | $2.87M | 0.03% | +416+0.8% | Added |
| First Trust Advisors LP | 54,325 | $2.85M | 0.00% | +54,325 | New |
| National Bank of Canada | 53,525 | $2.81M | 0.00% | +43,704+445.0% | Added |
| Stifel Financial Corp | 52,180 | $2.74M | 0.00% | +13,630+35.4% | Added |
| RMB Capital Management, LLC | 50,591 | $2.65M | 0.05% | −892−1.7% | Reduced |
| Lazard Asset Management LLC | 50,246 | $2.63M | 0.00% | −8,080−13.9% | Reduced |
| State of Wisconsin Investment Board | 48,172 | $2.53M | 0.01% | −3,495−6.8% | Reduced |
| MetLife Investment Management | 48,011 | $2.52M | 0.01% | −224−0.5% | Reduced |
| DekaBank Deutsche Girozentrale | 40,745 | $2.40M | 0.00% | 00.0% | Unchanged |
| Cambridge Investment Research Advisors, Inc. | 44,408 | $2.33M | 0.01% | −2,179−4.7% | Reduced |
| Privium Fund Management B.V. | 42,874 | $2.25M | 0.41% | +2,874+7.2% | Added |
| Manufacturers Life Insurance Company, The | 41,530 | $2.18M | 0.00% | −480−1.1% | Reduced |
| Palo Alto Investors LP | 41,226 | $2.16M | 0.30% | 00.0% | Unchanged |
| Qsemble Capital Management, LP | 40,586 | $2.13M | 0.18% | +40,586 | New |
| State of New Jersey Common Pension Fund D | 40,338 | $2.12M | 0.01% | +68+0.2% | Added |
| Tudor Investment Corp Et Al | 39,468 | $2.07M | 0.01% | +39,468 | New |
| Wealth Enhancement Trust Services, Inc. | 38,753 | $2.03M | 0.26% | +38,753 | New |