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CRISPR Therapeutics AG

CRSP
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001674416

In the last 90 days, CRISPR Therapeutics AG insiders filed 0 open-market purchases and 2 sales; 525 institutions reported holding it in 13F filings for Q2 2026, worth $4.16B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in CRISPR Therapeutics AG as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
482
+44 vs. Q3 2025
Shares held
76.5M
+4.26M (+5.9%) vs. Q3 2025
Total value
$4.01B
−$669.3M (−14.3%) vs. Q3 2025
New holders
96
149 more added
Sold out
52
129 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CRSP on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 482 institutions
Q1 2021: 446 institutionsQ2 2021: 501 institutionsQ3 2021: 477 institutionsQ4 2021: 448 institutionsQ1 2022: 446 institutionsQ2 2022: 437 institutionsQ3 2022: 436 institutionsQ4 2022: 399 institutionsQ1 2023: 383 institutionsQ2 2023: 420 institutionsQ3 2023: 410 institutionsQ4 2023: 472 institutionsQ1 2024: 483 institutionsQ2 2024: 450 institutionsQ3 2024: 417 institutionsQ4 2024: 406 institutionsQ1 2025: 398 institutionsQ2 2025: 435 institutionsQ3 2025: 442 institutionsQ4 2025: 482 institutionsQ1 2026: 494 institutionsQ2 2026: 525 institutions
Value heldQ4 2025: $4.01B
Q1 2021: $5.20BQ2 2021: $6.57BQ3 2021: $4.53BQ4 2021: $3.25BQ1 2022: $3.10BQ2 2022: $3.35BQ3 2022: $3.70BQ4 2022: $2.26BQ1 2023: $2.54BQ2 2023: $3.07BQ3 2023: $2.50BQ4 2023: $3.48BQ1 2024: $4.10BQ2 2024: $3.22BQ3 2024: $2.81BQ4 2024: $2.54BQ1 2025: $2.20BQ2 2025: $3.52BQ3 2025: $4.68BQ4 2025: $4.01BQ1 2026: $3.67BQ2 2026: $4.16B
Institutions holding CRSP and their total value by quarter
QuarterHoldersValue
Q2 2026525$4.16B
Q1 2026494$3.67B
Q4 2025482$4.01B
Q3 2025442$4.68B
Q2 2025435$3.52B
Q1 2025398$2.20B
Q4 2024406$2.54B
Q3 2024417$2.81B
Q2 2024450$3.22B
Q1 2024483$4.10B
Q4 2023472$3.48B
Q3 2023410$2.50B
Q2 2023420$3.07B
Q1 2023383$2.54B
Q4 2022399$2.26B
Q3 2022436$3.70B
Q2 2022437$3.35B
Q1 2022446$3.10B
Q4 2021448$3.25B
Q3 2021477$4.53B
Q2 2021501$6.57B
Q1 2021446$5.20B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding CRISPR Therapeutics AG; share changes are against Q3 2025.

Institutions holding CRSP in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Profund Advisors LLC38,110$2.00M0.06%+4,766+14.3%Added
West Family Investments, Inc.35,500$1.86M0.44%00.0%Unchanged
MML Investors Services, LLC34,761$1.82M0.00%+29,712+588.5%Added
Janus Henderson Group PLC34,774$1.82M0.00%00.0%Unchanged
Wellington Management Group LLP34,072$1.79M0.00%−2,414−6.6%Reduced
Blair William & Co33,424$1.75M0.00%−315−0.9%Reduced
Capital International Inc32,979$1.73M0.01%−725−2.2%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)32,039$1.68M0.00%−117−0.4%Reduced
Bouvel Investment Partners, LLC31,590$1.66M0.48%−157−0.5%Reduced
Susquehanna Portfolio Strategies, LLC31,015$1.63M0.03%−6,479−17.3%Reduced
Millennium Management LLC30,492$1.60M0.00%−55,790−64.7%Reduced
Russell Investments Group, Ltd.30,444$1.60M0.00%−11,589−27.6%Reduced
Mercer Global Advisors Inc28,412$1.49M0.00%+93+0.3%Added
Intech Investment Management LLC28,044$1.47M0.01%+5,140+22.4%Added
Blue Jean Financial LLC28,037$1.47M1.19%+28,037New
New York State Common Retirement Fund28,000$1.47M0.00%+1,800+6.9%Added
HRT Financial LP27,972$1.47M0.00%+27,972New
Hennion & Walsh Asset Management, Inc.27,711$1.45M0.05%+3,751+15.7%Added
PEAK6 LLC27,574$1.45M0.04%+27,574New
HighTower Advisors, LLC27,509$1.44M0.00%+783+2.9%Added
BNP Paribas Arbitrage, SA26,987$1.42M0.00%+1,961+7.8%Added
Handelsbanken Fonder AB26,900$1.41M0.00%+3,000+12.6%Added
Creative Planning26,889$1.41M0.00%−2,714−9.2%Reduced
Concurrent Investment Advisors, LLC26,341$1.38M0.02%+8,926+51.3%Added
Engineers Gate Manager LP25,950$1.36M0.02%+25,950New
B & T Capital Management DBA Alpha Capital Management25,803$1.35M0.19%+17,718+219.1%Added
Ipswich Investment Management Co., Inc.25,033$1.31M0.30%−165−0.7%Reduced
Franklin Resources Inc24,546$1.29M0.00%−1,271−4.9%Reduced
Westwood Holdings Group Inc.23,915$1.25M0.01%−1,204−4.8%Reduced
Leavell Investment Management, Inc.23,566$1.24M0.05%+400+1.7%Added
STRS Ohio23,523$1.23M0.00%00.0%Unchanged
Voya Investment Management LLC23,515$1.23M0.00%−5,296−18.4%Reduced
Police & Firemen's Retirement System of New Jersey23,481$1.23M0.01%+580+2.5%Added
Patriot Financial Group Insurance Agency, LLC23,234$1.22M0.15%−52−0.2%Reduced
Clough Capital Partners L P23,000$1.21M0.11%00.0%Unchanged
Asset Management One Co.,Ltd.22,132$1.19M0.00%00.0%Unchanged
Hedges Asset Management LLC22,775$1.19M0.84%+275+1.2%Added
Arizona State Retirement System22,677$1.19M0.01%−1,590−6.6%Reduced
Janney Montgomery Scott LLC22,292$1.17M0.00%+2,925+15.1%Added
Leonteq Securities AG22,020$1.15M0.06%+22,020New
State Board of Administration of Florida Retirement System21,361$1.12M0.00%00.0%Unchanged
Intesa Sanpaolo S.p.A.21,000$1.12M0.07%+21,000New
Balyasny Asset Management LLC21,202$1.11M0.00%+21,202New
Captrust Financial Advisors20,825$1.09M0.00%+2,843+15.8%Added
AQR Capital Management LLC20,746$1.09M0.00%−7,626−26.9%Reduced
Kestra Advisory Services, LLC20,636$1.08M0.00%+1,528+8.0%Added
China Universal Asset Management Co., Ltd.20,529$1.08M0.08%+4,587+28.8%Added
ProShare Advisors LLC20,447$1.07M0.00%+2,594+14.5%Added
Dark Forest Capital Management LP19,939$1.05M0.05%+19,939New
Virginia Retirement Systems Et Al19,880$1.04M0.01%+5,550+38.7%Added
Perigon Wealth Management, LLC19,059$999.5K0.02%+367+2.0%Added
Brave Asset Management Inc18,034$945.7K0.22%+5,000+38.4%Added
American Century Companies Inc18,021$945.0K0.00%00.0%Unchanged
Main Management ETF Advisors, LLC18,009$944.0K0.03%+184+1.0%Added
Walleye Trading LLC17,710$928.7K0.01%+17,710New
Banque Cantonale Vaudoise17,690$928.0K0.03%+127+0.7%Added
Nano Cap New Millennium Growth Fund L P17,500$917.7K0.78%+17,500New
KLP Kapitalforvaltning AS17,200$902.0K0.00%00.0%Unchanged
Generali Investments Towarzystwo Funduszy Inwestycyjnych17,000$891.5K0.43%−1,000−5.6%Reduced
Mariner, LLC16,909$885.8K0.00%+2,877+20.5%Added
Moran Wealth Management, LLC16,585$869.7K0.03%−5,112−23.6%Reduced
Virtu Financial LLC16,444$862.0K0.03%+16,444New
Inspire Advisors, LLC16,372$858.5K0.08%+2,513+18.1%Added
Farrow Financial Inc.16,130$845.9K0.49%−570−3.4%Reduced
Kassira Wealth Management LLC15,188$796.5K0.76%−557−3.5%Reduced
Advisory Services Network, LLC14,844$778.4K0.01%+1,024+7.4%Added
Warren Averett Asset Management, LLC14,507$760.7K0.01%+114+0.8%Added
Verition Fund Management LLC13,934$730.7K0.00%−10,844−43.8%Reduced
SG Americas Securities, LLC13,834$725.0K0.00%−6,885−33.2%Reduced
Bank Julius Baer & Co. Ltd, Zurich13,811$724.3K0.00%+984+7.7%Added
HSBC Holdings PLC13,720$722.5K0.00%+4,114+42.8%Added
Axxcess Wealth Management, LLC13,022$682.9K0.01%+764+6.2%Added
Vontobel Holding Ltd.13,002$681.8K0.00%+8,301+176.6%Added
Beacon Pointe Advisors, LLC12,936$678.4K0.00%+110+0.9%Added
SEI Investments Co12,658$663.6K0.00%+516+4.2%Added
SFE Investment Counsel12,600$660.7K0.10%+1,040+9.0%Added
Brinker Capital Investments, LLC12,591$660.3K0.00%+4,489+55.4%Added
Teacher Retirement System of Texas12,150$637.1K0.00%−7,985−39.7%Reduced
Jacobs Equity LLC12,090$634.0K0.61%+12,090New
Virtus Investment Advisers, Inc.12,056$632.2K0.17%+1,291+12.0%Added
Steel Peak Wealth Management LLC12,032$631.0K0.02%+3,095+34.6%Added
Capital Investment Advisory Services, LLC11,948$626.6K0.04%−4,290−26.4%Reduced
Capital Group Investment Management Pte. Ltd.11,707$613.9K0.10%−1,236−9.5%Reduced
Kestra Private Wealth Services, LLC11,458$600.9K0.01%+1,250+12.2%Added
Northwestern Mutual Wealth Management Co11,446$600.2K0.00%+2,033+21.6%Added
Koss-Olinger Consulting, LLC11,447$600.0K0.05%−30,750−72.9%Reduced
Sanctuary Advisors, LLC11,176$586.1K0.00%+1,517+15.7%Added
Bartlett & Co. Wealth Management LLC11,100$582.1K0.01%00.0%Unchanged
WCG Wealth Advisors LLC10,937$573.5K0.02%+10,937New
Federated Hermes, Inc.10,931$573.2K0.00%−11,614−51.5%Reduced
Bank of Montreal10,468$548.9K0.00%−176,751−94.4%Reduced
Hilltop Holdings Inc.10,322$541.3K0.03%+10,322New
Horizon Kinetics Asset Management LLC10,239$536.9K0.01%−443−4.1%Reduced
CIBC World Markets Inc.10,018$525.3K0.00%−1,934−16.2%Reduced
NLB Skladi, upravljanje premozenja, d.o.o.10,000$524.4K0.02%+10,000New
Merit Financial Group, LLC9,933$520.9K0.00%−524−5.0%Reduced
Wincap Financial LLC9,790$513.4K0.35%+378+4.0%Added
Prudential Financial Inc9,580$502.4K0.00%+1,045+12.2%Added
PSP Research LLC9,580$502.4K0.44%+9,580New
Allworth Financial LP9,550$500.8K0.00%+249+2.7%Added