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CRISPR Therapeutics AG

CRSP
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001674416

In the last 90 days, CRISPR Therapeutics AG insiders filed 0 open-market purchases and 2 sales; 525 institutions reported holding it in 13F filings for Q2 2026, worth $4.16B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q3 2025

Institutional positions in CRISPR Therapeutics AG as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
442
+16 vs. Q2 2025
Shares held
72.2M
+343.2K (+0.5%) vs. Q2 2025
Total value
$4.68B
+$1.19B (+33.9%) vs. Q2 2025
New holders
73
148 more added
Sold out
57
118 more reduced

9 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CRSP on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 442 institutions
Q1 2021: 446 institutionsQ2 2021: 501 institutionsQ3 2021: 477 institutionsQ4 2021: 448 institutionsQ1 2022: 446 institutionsQ2 2022: 437 institutionsQ3 2022: 436 institutionsQ4 2022: 399 institutionsQ1 2023: 383 institutionsQ2 2023: 420 institutionsQ3 2023: 410 institutionsQ4 2023: 472 institutionsQ1 2024: 483 institutionsQ2 2024: 450 institutionsQ3 2024: 417 institutionsQ4 2024: 406 institutionsQ1 2025: 398 institutionsQ2 2025: 435 institutionsQ3 2025: 442 institutionsQ4 2025: 482 institutionsQ1 2026: 494 institutionsQ2 2026: 525 institutions
Value heldQ3 2025: $4.68B
Q1 2021: $5.20BQ2 2021: $6.57BQ3 2021: $4.53BQ4 2021: $3.25BQ1 2022: $3.10BQ2 2022: $3.35BQ3 2022: $3.70BQ4 2022: $2.26BQ1 2023: $2.54BQ2 2023: $3.07BQ3 2023: $2.50BQ4 2023: $3.48BQ1 2024: $4.10BQ2 2024: $3.22BQ3 2024: $2.81BQ4 2024: $2.54BQ1 2025: $2.20BQ2 2025: $3.52BQ3 2025: $4.68BQ4 2025: $4.01BQ1 2026: $3.67BQ2 2026: $4.16B
Institutions holding CRSP and their total value by quarter
QuarterHoldersValue
Q2 2026525$4.16B
Q1 2026494$3.67B
Q4 2025482$4.01B
Q3 2025442$4.68B
Q2 2025435$3.52B
Q1 2025398$2.20B
Q4 2024406$2.54B
Q3 2024417$2.81B
Q2 2024450$3.22B
Q1 2024483$4.10B
Q4 2023472$3.48B
Q3 2023410$2.50B
Q2 2023420$3.07B
Q1 2023383$2.54B
Q4 2022399$2.26B
Q3 2022436$3.70B
Q2 2022437$3.35B
Q1 2022446$3.10B
Q4 2021448$3.25B
Q3 2021477$4.53B
Q2 2021501$6.57B
Q1 2021446$5.20B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding CRISPR Therapeutics AG; share changes are against Q2 2025.

Institutions holding CRSP in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
ARK Investment Management LLCSuperinvestorARK Invest9,786,973$634.3M3.78%−395,617−3.9%Reduced
BlackRock, Inc.7,050,145$456.9M0.01%+983,787+16.2%Added
Capital International Investors5,649,258$366.1M0.06%+55,511+1.0%Added
Orbis Allan Gray Ltd4,982,085$322.9M1.39%+2,217,553+80.2%Added
State Street Corp4,007,233$259.7M0.01%+736,637+22.5%Added
T. Rowe Price Investment Management, Inc.3,282,584$212.7M0.13%−400,442−10.9%Reduced
Vanguard Group Inc2,364,645$153.3M0.00%+66,556+2.9%Added
UBS Group AG2,339,056$151.6M0.03%−504,521−17.7%Reduced
Sumitomo Mitsui Trust Holdings, Inc.2,163,675$140.2M0.08%−251,163−10.4%Reduced
Nikko Asset Management Americas, Inc.2,163,675$140.2M1.36%−250,596−10.4%Reduced
Geode Capital Management, LLC2,141,170$138.8M0.01%+69,287+3.3%Added
Sr One Capital Management, LP2,038,763$132.1M19.11%+989,812+94.4%Added
FMR LLC1,885,663$122.2M0.01%−43,491−2.3%Reduced
Morgan Stanley1,397,859$90.6M0.01%+886,479+173.4%Added
EcoR1 Capital, LLC1,389,276$90.0M4.33%00.0%Unchanged
Bank of America Corp1,124,119$72.9M0.01%−324,296−22.4%Reduced
NEA Management Company, LLC1,058,570$68.6M3.76%−529,284−33.3%Reduced
Two Sigma Investments, LP1,044,689$67.7M0.10%−501,277−32.4%Reduced
Charles Schwab Investment Management Inc985,770$63.9M0.01%+52,566+5.6%Added
Loomis Sayles & Co L P909,714$59.0M0.07%+52,827+6.2%Added
Dimensional Fund Advisors LP877,029$56.8M0.01%−40,683−4.4%Reduced
Susquehanna International Group, LLP814,324$52.8M0.08%+44,379+5.8%Added
Northern Trust Corp779,930$50.5M0.01%+18,815+2.5%Added
JPMorgan Chase & Co593,416$38.5M0.00%+272,322+84.8%Added
Two Sigma Advisers, LP572,972$37.1M0.07%−771,728−57.4%Reduced
Royal Bank of Canada466,170$30.2M0.01%+129,032+38.3%Added
Barclays PLC349,851$22.7M0.01%−30,772−8.1%Reduced
Ameriprise Financial Inc311,863$20.3M0.00%+49,774+19.0%Added
Bank of New York Mellon Corp304,607$19.7M0.00%+2,648+0.9%Added
Wells Fargo & Company303,178$19.6M0.00%+67,438+28.6%Added
Davy Global Fund Management Ltd283,111$18.3M1.24%+87,509+44.7%Added
Contrarius Group Holdings Ltd270,350$17.5M0.79%−104,604−27.9%Reduced
Vestmark Advisory Solutions, Inc.238,962$15.5M0.30%−246,013−50.7%Reduced
Goldman Sachs Group Inc233,542$15.1M0.00%+12,942+5.9%Added
LPL Financial LLC211,061$13.7M0.00%+16,482+8.5%Added
Pictet Asset Management Holding SA192,593$12.3M0.01%−43,327−18.4%Reduced
Bank of Montreal187,219$12.1M0.01%−306,524−62.1%Reduced
Nuveen, LLC182,841$11.8M0.00%−2,012−1.1%Reduced
TD Asset Management Inc174,616$11.3M0.01%−53,800−23.6%Reduced
O'Neil Global Advisors, Inc.168,715$10.9M2.01%+168,715New
Citadel Advisors LLC167,101$10.8M0.01%+148,223+785.2%Added
Swiss National Bank159,100$10.3M0.01%+2,700+1.7%Added
Rafferty Asset Management, LLC154,295$10.0M0.03%+39,947+34.9%Added
Versant Venture Management, LLC148,831$9.65M4.54%−349,727−70.1%Reduced
Rockefeller Capital Management L.P.148,531$9.63M0.02%+33,175+28.8%Added
Woodline Partners LP143,575$9.31M0.04%−5,692−3.8%Reduced
Nordea Investment Management AB131,300$8.39M0.01%+3,800+3.0%Added
Rhumbline Advisers123,907$8.03M0.01%+140.0%Added
Marex Group plc123,769$8.02M0.10%+104,286+535.3%Added
Private Advisor Group, LLC118,113$7.65M0.04%+6,164+5.5%Added
Nwam LLC101,769$7.53M0.41%+83,454+455.7%Added
Reynders McVeigh Capital Management, LLC113,000$7.32M0.34%+1,569+1.4%Added
Raymond James Financial Inc109,830$7.12M0.00%+12,257+12.6%Added
California Public Employees Retirement System109,372$7.09M0.00%+5,744+5.5%Added
Tang Capital Management LLC100,000$6.48M0.25%+100,000New
Capital International Sarl99,657$6.46M0.11%+8,140+8.9%Added
Mirae Asset Global ETFs Holdings Ltd.99,204$6.42M0.01%−6,194−5.9%Reduced
EverSource Wealth Advisors, LLC97,434$6.31M0.25%+4,491+4.8%Added
Group One Trading, L.P.97,242$6.30M0.19%+91,530+1,602.4%Added
Baker Chad R93,205$6.04M1.04%00.0%Unchanged
Legal & General Group Plc92,479$5.99M0.00%−37,088−28.6%Reduced
Wealth Enhancement Advisory Services, LLC84,016$5.93M0.01%+1,409+1.7%Added
Alliancebernstein L.P.86,334$5.60M0.00%−286−0.3%Reduced
Millennium Management LLC86,282$5.59M0.00%+16,189+23.1%Added
Van Eck Associates Corp83,644$5.42M0.01%+634+0.8%Added
Price T Rowe Associates Inc76,535$4.96M0.00%+10,168+15.3%Added
California State Teachers Retirement System74,911$4.85M0.00%+40.0%Added
Slow Capital, Inc.73,287$4.75M0.56%−2,109−2.8%Reduced
Himension Fund72,339$4.69M0.29%−10,781−13.0%Reduced
Envestnet Asset Management Inc70,389$4.56M0.00%+2,447+3.6%Added
Commonwealth Equity Services, LLC69,097$4.48M0.01%+6,523+10.4%Added
Congress Asset Management Co68,110$4.41M0.03%−294−0.4%Reduced
Invesco Ltd.65,327$4.23M0.00%−1,321−2.0%Reduced
Tower Research Capital LLC (TRC)64,946$4.21M0.12%+42,477+189.0%Added
Deutsche Bank AG64,802$4.20M0.00%+7,542+13.2%Added
Cetera Investment Advisers63,830$4.14M0.00%+15,815+32.9%Added
Del-Sette Capital Management, LLC62,494$4.05M2.52%−1,349−2.1%Reduced
Capital International Ltd61,552$3.99M0.14%00.0%Unchanged
Citigroup Inc60,489$3.92M0.00%−66,403−52.3%Reduced
Lazard Asset Management LLC58,326$3.78M0.01%−1,007−1.7%Reduced
Guggenheim Capital LLC57,461$3.72M0.03%−1,027−1.8%Reduced
Green Alpha Advisors, LLC55,012$3.57M3.44%−3,451−5.9%Reduced
Benjamin Edwards Inc54,220$3.51M0.04%−3,540−6.1%Reduced
State of Wisconsin Investment Board51,667$3.35M0.01%+102+0.2%Added
RMB Capital Management, LLC51,483$3.34M0.06%+66+0.1%Added
Pathway Capital Management, LP50,049$3.24M15.95%+50,049New
Advisor Group Holdings, Inc.55,935$3.21M0.00%+3,900+7.5%Added
MetLife Investment Management48,235$3.13M0.02%−1,104−2.2%Reduced
Cambridge Investment Research Advisors, Inc.46,587$3.02M0.01%+1,120+2.5%Added
Jones Financial Companies LLLP44,715$2.76M0.00%+14,948+50.2%Added
Russell Investments Group, Ltd.42,033$2.72M0.00%+42,033New
Manufacturers Life Insurance Company, The42,010$2.72M0.00%+2,697+6.9%Added
Palo Alto Investors LP41,226$2.67M0.49%−3,399−7.6%Reduced
State of New Jersey Common Pension Fund D40,270$2.61M0.01%−9,915−19.8%Reduced
DekaBank Deutsche Girozentrale40,745$2.61M0.00%00.0%Unchanged
Privium Fund Management B.V.40,000$2.59M0.47%−4,700−10.5%Reduced
Stifel Financial Corp38,550$2.50M0.00%−4,400−10.2%Reduced
Susquehanna Portfolio Strategies, LLC37,494$2.43M0.04%+6,479+20.9%Added
Wellington Management Group LLP36,486$2.36M0.00%+36,486New
West Family Investments, Inc.35,500$2.30M0.51%00.0%Unchanged