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Caribou Biosciences, Inc.

CRBU
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001619856

No open-market purchases or sales by Caribou Biosciences, Inc. insiders were filed in the last 90 days; 137 institutions reported holding it in 13F filings for Q2 2026, worth $84.8M in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q3 2025

Institutional positions in Caribou Biosciences, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
117
−12 vs. Q2 2025
Shares held
37.2M
−3.61M (−8.8%) vs. Q2 2025
Total value
$87.0M
+$35.8M (+69.9%) vs. Q2 2025
New holders
16
21 more added
Sold out
28
47 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CRBU on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 117 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 88 institutionsQ4 2021: 93 institutionsQ1 2022: 104 institutionsQ2 2022: 120 institutionsQ3 2022: 113 institutionsQ4 2022: 133 institutionsQ1 2023: 126 institutionsQ2 2023: 121 institutionsQ3 2023: 126 institutionsQ4 2023: 144 institutionsQ1 2024: 151 institutionsQ2 2024: 140 institutionsQ3 2024: 129 institutionsQ4 2024: 133 institutionsQ1 2025: 131 institutionsQ2 2025: 129 institutionsQ3 2025: 117 institutionsQ4 2025: 124 institutionsQ1 2026: 137 institutionsQ2 2026: 137 institutions
Value heldQ3 2025: $87.0M
Q1 2021: $0Q2 2021: $0Q3 2021: $704.7MQ4 2021: $464.7MQ1 2022: $313.2MQ2 2022: $203.0MQ3 2022: $456.8MQ4 2022: $273.8MQ1 2023: $238.3MQ2 2023: $185.5MQ3 2023: $338.5MQ4 2023: $395.8MQ1 2024: $343.0MQ2 2024: $87.6MQ3 2024: $103.1MQ4 2024: $93.1MQ1 2025: $45.8MQ2 2025: $51.2MQ3 2025: $87.0MQ4 2025: $58.8MQ1 2026: $71.3MQ2 2026: $84.8M
Institutions holding CRBU and their total value by quarter
QuarterHoldersValue
Q2 2026137$84.8M
Q1 2026137$71.3M
Q4 2025124$58.8M
Q3 2025117$87.0M
Q2 2025129$51.2M
Q1 2025131$45.8M
Q4 2024133$93.1M
Q3 2024129$103.1M
Q2 2024140$87.6M
Q1 2024151$343.0M
Q4 2023144$395.8M
Q3 2023126$338.5M
Q2 2023121$185.5M
Q1 2023126$238.3M
Q4 2022133$273.8M
Q3 2022113$456.8M
Q2 2022120$203.0M
Q1 2022104$313.2M
Q4 202193$464.7M
Q3 202188$704.7M
Q2 20210$0
Q1 20210$0

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Caribou Biosciences, Inc.; share changes are against Q2 2025.

Institutions holding CRBU in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Cambridge Investment Research Advisors, Inc.582,387$1.36M0.00%−2,059−0.4%Reduced
Maverick Capital LtdSuperinvestorMaverick Capital652,542$1.52M0.02%00.0%Unchanged
FMR LLC729,002$1.70M0.00%−439−0.1%Reduced
Pale Fire Capital SE775,055$1.81M0.20%00.0%Unchanged
Renaissance Technologies LLC780,421$1.82M0.00%+248,300+46.7%Added
Two Sigma Investments, LP783,590$1.83M0.00%−144,935−15.6%Reduced
Geode Capital Management, LLC985,126$2.30M0.00%+4,197+0.4%Added
Bank of America Corp1,074,442$2.50M0.00%+265,542+32.8%Added
Dimensional Fund Advisors LP1,210,310$2.82M0.00%−97,045−7.4%Reduced
Two Sigma Advisers, LP1,227,400$2.86M0.01%−220,400−15.2%Reduced
PFM Health Sciences, LP1,358,831$3.17M0.27%00.0%Unchanged
Standard Life Aberdeen plc1,388,905$3.24M0.01%+491,326+54.7%Added
BlackRock, Inc.1,459,320$3.40M0.00%−424,156−22.5%Reduced
Kynam Capital Management, LP3,067,774$7.15M0.53%00.0%Unchanged
Millennium Management LLC3,216,535$7.49M0.01%+1,665,946+107.4%Added
Vanguard Group Inc4,226,926$9.85M0.00%+137,060+3.4%Added
Pfizer Inc4,690,431$10.9M2.50%00.0%Unchanged
Gsa Capital Partners LLP0$00.00%−166,396−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−155,521−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−137,211−100.0%Sold out
Woodline Partners LP0$00.00%−122,833−100.0%Sold out
HRT Financial LP0$00.00%−105,865−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−105,006−100.0%Sold out
Jain Global LLC0$00.00%−101,178−100.0%Sold out
Ieq Capital, LLC0$00.00%−100,198−100.0%Sold out
Quadrature Capital Ltd0$00.00%−91,110−100.0%Sold out
Keystone Financial Group0$00.00%−63,975−100.0%Sold out
Eqis Capital Management, Inc.0$00.00%−32,513−100.0%Sold out
Cerity Partners LLC0$00.00%−31,802−100.0%Sold out
Wealth Enhancement Advisory Services, LLC0$00.00%−22,083−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−23,738−100.0%Sold out
DRW Securities, LLC0$00.00%−22,200−100.0%Sold out
Ground Swell Capital, LLC0$00.00%−16,306−100.0%Sold out
Engineers Gate Manager LP0$00.00%−15,782−100.0%Sold out
Jump Financial, LLC0$00.00%−14,207−100.0%Sold out
Pathstone Holdings, LLC0$00.00%−13,011−100.0%Sold out
Prudential Financial Inc0$00.00%−10,600−100.0%Sold out
Raymond James Financial Inc0$00.00%−8,727−100.0%Sold out
Clear Street Markets LLC0$00.00%−2,735−100.0%Sold out
Federation des caisses Desjardins du Quebec0$00.00%−900−100.0%Sold out
True Wealth Design, LLC0$00.00%−791−100.0%Sold out
JPMorgan Chase & Co0$00.00%−710−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−351−100.0%Sold out
Allworth Financial LP0$00.00%−156−100.0%Sold out
Northwestern Mutual Wealth Management Co0$00.00%−4−100.0%Sold out