Biocryst Pharmaceuticals Inc
BCRX- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0000882796
No open-market purchases or sales by Biocryst Pharmaceuticals Inc insiders were filed in the last 90 days; 319 institutions reported holding it in 13F filings for Q2 2026, worth $2.61B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Biocryst Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 273
- −8 vs. Q3 2025
- Shares held
- 212.5M
- +19.7M (+10.2%) vs. Q3 2025
- Total value
- $1.66B
- +$193.5M (+13.2%) vs. Q3 2025
- New holders
- 49
- 91 more added
- Sold out
- 57
- 101 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting BCRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 319 | $2.61B |
| Q1 2026 | 303 | $2.37B |
| Q4 2025 | 273 | $1.66B |
| Q3 2025 | 286 | $1.47B |
| Q2 2025 | 294 | $1.77B |
| Q1 2025 | 274 | $1.32B |
| Q4 2024 | 258 | $1.26B |
| Q3 2024 | 257 | $1.32B |
| Q2 2024 | 242 | $1.08B |
| Q1 2024 | 238 | $915.0M |
| Q4 2023 | 236 | $1.06B |
| Q3 2023 | 233 | $1.24B |
| Q2 2023 | 236 | $1.23B |
| Q1 2023 | 242 | $1.42B |
| Q4 2022 | 230 | $1.80B |
| Q3 2022 | 234 | $1.87B |
| Q2 2022 | 221 | $1.61B |
| Q1 2022 | 233 | $2.07B |
| Q4 2021 | 206 | $1.63B |
| Q3 2021 | 197 | $1.48B |
| Q2 2021 | 195 | $1.65B |
| Q1 2021 | 191 | $1.06B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Biocryst Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Los Angeles Capital Management LLC | 355,055 | $2.57M | 0.01% | +45,945+14.9% | Added |
| State of Wisconsin Investment Board | 347,190 | $2.71M | 0.01% | −28,661−7.6% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 357,086 | $2.79M | 0.01% | −491,476−57.9% | Reduced |
| Assenagon Asset Management S.A. | 359,580 | $2.80M | 0.00% | −2,733,012−88.4% | Reduced |
| First Trust Advisors LP | 374,961 | $2.92M | 0.00% | −360,026−49.0% | Reduced |
| Principal Financial Group Inc | 376,568 | $2.94M | 0.00% | +132,159+54.1% | Added |
| UBS Asset Management Americas Inc | 378,853 | $2.96M | 0.00% | −15,887−4.0% | Reduced |
| Rafferty Asset Management, LLC | 382,556 | $2.98M | 0.01% | +13,234+3.6% | Added |
| Swiss National Bank | 394,368 | $3.08M | 0.00% | +9,000+2.3% | Added |
| Man Group plc | 407,850 | $3.18M | 0.01% | +53,366+15.1% | Added |
| DAFNA Capital Management LLC | 418,255 | $3.26M | 0.76% | +200,000+91.6% | Added |
| Voloridge Investment Management, LLC | 449,743 | $3.51M | 0.01% | −507,278−53.0% | Reduced |
| Deutsche Bank AG | 491,086 | $3.83M | 0.00% | −577,929−54.1% | Reduced |
| Hillsdale Investment Management Inc. | 559,100 | $4.36M | 0.12% | −2,500−0.4% | Reduced |
| FMR LLC | 560,182 | $4.37M | 0.00% | −93,632−14.3% | Reduced |
| Franklin Resources Inc | 570,189 | $4.45M | 0.00% | +104,851+22.5% | Added |
| Bank of New York Mellon Corp | 607,992 | $4.74M | 0.00% | −11,996−1.9% | Reduced |
| Voya Investment Management LLC | 625,490 | $4.88M | 0.00% | +169,899+37.3% | Added |
| Jane Street Group, LLC | 649,357 | $5.06M | 0.01% | −1,198,989−64.9% | Reduced |
| Susquehanna International Group, LLP | 671,693 | $5.24M | 0.01% | +425,932+173.3% | Added |
| PDT Partners, LLC | 683,416 | $5.33M | 0.35% | 00.0% | Unchanged |
| AQR Capital Management LLC | 704,291 | $5.49M | 0.00% | −295,494−29.6% | Reduced |
| HRT Financial LP | 716,826 | $5.59M | 0.02% | +658,920+1,137.9% | Added |
| Barclays PLC | 726,367 | $5.67M | 0.00% | −55,865−7.1% | Reduced |
| Pictet Asset Management Holding SA | 740,510 | $5.71M | 0.01% | −455,809−38.1% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 778,521 | $6.07M | 0.09% | +778,521 | New |
| Tang Capital Management LLC | 800,000 | $6.24M | 0.31% | 00.0% | Unchanged |
| Sphera Funds Management Ltd. | 837,889 | $6.54M | 1.37% | +837,889 | New |
| JPMorgan Chase & Co | 843,370 | $6.58M | 0.00% | −289,007−25.5% | Reduced |
| Parkman Healthcare Partners LLC | 900,057 | $7.02M | 0.67% | −112,607−11.1% | Reduced |
| Jump Financial, LLC | 910,930 | $7.11M | 0.09% | −13,846−1.5% | Reduced |
| Standard Life Aberdeen plc | 913,593 | $7.13M | 0.01% | +913,593 | New |
| Hudson Bay Capital Management LP | 1,017,374 | $7.94M | 0.05% | +1,017,374 | New |
| Jacobs Levy Equity Management, Inc | 1,031,488 | $8.05M | 0.03% | +661,025+178.4% | Added |
| Jupiter Asset Management Ltd | 1,197,619 | $9.34M | 0.07% | −858,296−41.7% | Reduced |
| Point72 Asset Management, L.P. | 1,213,576 | $9.47M | 0.01% | +975,389+409.5% | Added |
| Dimensional Fund Advisors LP | 1,228,852 | $9.59M | 0.00% | +1,228,852 | New |
| D. E. Shaw & Co., Inc. | 1,247,466 | $9.73M | 0.01% | −461,870−27.0% | Reduced |
| Citadel Advisors LLC | 1,298,902 | $10.1M | 0.01% | −60,980−4.5% | Reduced |
| Invesco Ltd. | 1,354,897 | $10.6M | 0.00% | +392,521+40.8% | Added |
| Nantahala Capital Management, LLC | 1,356,377 | $10.6M | 0.63% | +1,356,377 | New |
| Bank of America Corp | 1,535,557 | $12.0M | 0.00% | −367,262−19.3% | Reduced |
| Squarepoint Ops LLC | 1,659,192 | $12.9M | 0.03% | +550,532+49.7% | Added |
| OrbiMed Advisors LLC | 1,741,800 | $13.6M | 0.28% | +840,300+93.2% | Added |
| Morgan Stanley | 1,745,563 | $13.6M | 0.00% | −3,457,396−66.5% | Reduced |
| Stifel Financial Corp | 1,824,517 | $14.2M | 0.01% | +1,525+0.1% | Added |
| Northern Trust Corp | 1,856,903 | $14.5M | 0.00% | −35,140−1.9% | Reduced |
| Rice Hall James & Associates, LLC | 1,904,146 | $14.9M | 0.82% | +23,757+1.3% | Added |
| Charles Schwab Investment Management Inc | 2,004,939 | $15.6M | 0.00% | +10,535+0.5% | Added |
| Renaissance Technologies LLC | 2,128,821 | $16.6M | 0.03% | −11,713−0.5% | Reduced |
| Elmind Capital, LP | 2,150,000 | $16.8M | 4.95% | +2,150,000 | New |
| Qube Research & Technologies Ltd | 2,164,162 | $16.9M | 0.02% | −246,200−10.2% | Reduced |
| Vestal Point Capital, LP | 2,250,000 | $17.6M | 0.64% | +2,250,000 | New |
| Fisher Asset Management, LLC | 2,467,567 | $19.2M | 0.01% | −165,129−6.3% | Reduced |
| BNP Paribas Arbitrage, SA | 2,542,714 | $19.8M | 0.01% | +448,436+21.4% | Added |
| Baker Bros. Advisors LP | 2,822,727 | $22.0M | 0.13% | +2,822,727 | New |
| Eversept Partners, LP | 2,992,895 | $23.3M | 1.31% | +1,619,270+117.9% | Added |
| GW&K Investment Management, LLC | 3,160,924 | $24.7M | 0.21% | +963,159+43.8% | Added |
| Perceptive Advisors LLC | 3,162,529 | $24.7M | 0.45% | +3,162,529 | New |
| Goldman Sachs Group Inc | 3,212,785 | $25.1M | 0.00% | +500,979+18.5% | Added |
| Nuveen, LLC | 3,612,366 | $28.2M | 0.01% | −5,516−0.2% | Reduced |
| Royalty Pharma Sub-Manager, LLC | 3,846,154 | $30.0M | 17.51% | +3,846,154 | New |
| Two Sigma Advisers, LP | 4,089,112 | $31.9M | 0.06% | −151,600−3.6% | Reduced |
| Two Sigma Investments, LP | 4,515,317 | $35.2M | 0.05% | +95,688+2.2% | Added |
| Geode Capital Management, LLC | 5,053,786 | $39.4M | 0.00% | +1,4790.0% | Added |
| UBS Group AG | 5,263,914 | $41.1M | 0.01% | −703,823−11.8% | Reduced |
| Janus Henderson Group PLC | 7,404,386 | $57.8M | 0.03% | +7,310,745+7,807.2% | Added |
| Kynam Capital Management, LP | 9,366,526 | $73.1M | 4.76% | −23,744−0.3% | Reduced |
| State Street Corp | 11,073,211 | $86.4M | 0.00% | +1,265,773+12.9% | Added |
| Deerfield Management Company, L.P. (Series C) | 14,341,000 | $111.9M | 1.43% | +2,172,000+17.8% | Added |
| Ra Capital Management, L.P. | 15,827,186 | $123.5M | 1.26% | +15,827,186 | New |
| BlackRock, Inc. | 21,137,791 | $164.9M | 0.00% | −108,085−0.5% | Reduced |
| Vanguard Group Inc | 22,273,375 | $173.7M | 0.00% | +482,494+2.2% | Added |
| Alkeon Capital Management LLC | 0 | $0 | 0.00% | −5,464,021−100.0% | Sold out |
| Hood River Capital Management LLC | 0 | $0 | 0.00% | −3,620,261−100.0% | Sold out |
| Avoro Capital Advisors LLC | 0 | $0 | 0.00% | −1,250,000−100.0% | Sold out |
| Segall Bryant & Hamill, LLC | 0 | $0 | 0.00% | −1,134,813−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −731,411−100.0% | Sold out |
| Algert Global LLC | 0 | $0 | 0.00% | −713,088−100.0% | Sold out |
| Schroder Investment Management Group | 0 | $0 | 0.00% | −535,968−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −434,531−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −364,457−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −325,795−100.0% | Sold out |
| Public Sector Pension Investment Board | 0 | $0 | 0.00% | −264,800−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −262,465−100.0% | Sold out |
| Massachusetts Financial Services Co | 0 | $0 | 0.00% | −131,711−100.0% | Sold out |
| Magnetar Financial LLC | 0 | $0 | 0.00% | −116,020−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −107,192−100.0% | Sold out |
| Cantor Fitzgerald, L. P. | 0 | $0 | 0.00% | −106,307−100.0% | Sold out |
| Alps Advisors Inc | 0 | $0 | 0.00% | −101,125−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −87,048−100.0% | Sold out |
| Ieq Capital, LLC | 0 | $0 | 0.00% | −71,950−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −63,242−100.0% | Sold out |
| Axq Capital, LP | 0 | $0 | 0.00% | −58,423−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −57,451−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Moody National Bank Trust Division | 0 | $0 | 0.00% | −46,011−100.0% | Sold out |
| Semanteon Capital Management, LP | 0 | $0 | 0.00% | −43,544−100.0% | Sold out |
| STRS Ohio | 0 | $0 | 0.00% | −40,700−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −40,602−100.0% | Sold out |