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Avalo Therapeutics, Inc.

AVTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001534120

In the last 90 days, Avalo Therapeutics, Inc. insiders filed 0 open-market purchases and 9 sales; 126 institutions reported holding it in 13F filings for Q2 2026, worth $1.31B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Avalo Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
84
+18 vs. Q3 2025
Shares held
19.9M
+4.57M (+29.8%) vs. Q3 2025
Total value
$361.1M
+$166.4M (+85.5%) vs. Q3 2025
New holders
33
28 more added
Sold out
15
13 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AVTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 84 institutions
Q1 2021: 70 institutionsQ2 2021: 71 institutionsQ3 2021: 77 institutionsQ4 2021: 75 institutionsQ1 2022: 71 institutionsQ2 2022: 54 institutionsQ3 2022: 27 institutionsQ4 2022: 28 institutionsQ1 2023: 32 institutionsQ2 2023: 26 institutionsQ3 2023: 28 institutionsQ4 2023: 12 institutionsQ1 2024: 18 institutionsQ2 2024: 21 institutionsQ3 2024: 29 institutionsQ4 2024: 33 institutionsQ1 2025: 34 institutionsQ2 2025: 36 institutionsQ3 2025: 66 institutionsQ4 2025: 84 institutionsQ1 2026: 97 institutionsQ2 2026: 126 institutions
Value heldQ4 2025: $361.1M
Q1 2021: $180.4MQ2 2021: $218.1MQ3 2021: $175.5MQ4 2021: $136.0MQ1 2022: $56.2MQ2 2022: $34.7MQ3 2022: $18.4MQ4 2022: $28.0MQ1 2023: $16.0MQ2 2023: $862.7KQ3 2023: $158.9KQ4 2023: $209.4KQ1 2024: $1.90MQ2 2024: $9.62MQ3 2024: $63.2MQ4 2024: $56.0MQ1 2025: $66.1MQ2 2025: $39.1MQ3 2025: $194.7MQ4 2025: $361.1MQ1 2026: $469.6MQ2 2026: $1.31B
Institutions holding AVTX and their total value by quarter
QuarterHoldersValue
Q2 2026126$1.31B
Q1 202697$469.6M
Q4 202584$361.1M
Q3 202566$194.7M
Q2 202536$39.1M
Q1 202534$66.1M
Q4 202433$56.0M
Q3 202429$63.2M
Q2 202421$9.62M
Q1 202418$1.90M
Q4 202312$209.4K
Q3 202328$158.9K
Q2 202326$862.7K
Q1 202332$16.0M
Q4 202228$28.0M
Q3 202227$18.4M
Q2 202254$34.7M
Q1 202271$56.2M
Q4 202175$136.0M
Q3 202177$175.5M
Q2 202171$218.1M
Q1 202170$180.4M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Avalo Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding AVTX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BVF Inc1,355,257$24.6M0.83%+10.0%Added
Nantahala Capital Management, LLC1,235,000$22.4M1.34%00.0%Unchanged
OrbiMed Advisors LLC1,187,300$21.6M0.44%−162,000−12.0%Reduced
Affinity Asset Advisors, LLC1,051,054$19.1M1.37%+44,837+4.5%Added
Caligan Partners LP881,533$16.0M1.47%+48,200+5.8%Added
Vanguard Group Inc804,084$14.6M0.00%+111,447+16.1%Added
Ra Capital Management, L.P.662,968$12.0M0.12%00.0%Unchanged
Millennium Management LLC659,979$12.0M0.01%+522,548+380.2%Added
Point72 Asset Management, L.P.627,502$11.4M0.02%−426,481−40.5%Reduced
Bank of America Corp621,350$11.3M0.00%+15,508+2.6%Added
Adage Capital Partners GP, L.L.C.550,000$9.99M0.02%+291,231+112.5%Added
Silverarc Capital Management, LLC524,436$9.52M1.38%−196,486−27.3%Reduced
Marshall Wace, LLP507,550$9.22M0.01%+451,541+806.2%Added
Commodore Capital LP483,000$8.77M0.58%00.0%Unchanged
TCG Crossover Management, LLC483,000$8.77M0.29%00.0%Unchanged
UBS Group AG477,816$8.68M0.00%+432,608+956.9%Added
Jennison Associates LLC475,625$8.64M0.01%+475,625New
Soleus Capital Management, L.P.441,978$8.03M0.34%+441,978New
Balyasny Asset Management LLC439,312$7.98M0.01%−378,124−46.3%Reduced
Citadel Advisors LLC419,491$7.62M0.01%−62,178−12.9%Reduced
Patient Square Capital LP311,966$5.67M1.21%+211,966+212.0%Added
BlackRock, Inc.289,571$5.26M0.00%+135,320+87.7%Added
Boxer Capital Management, LLC275,000$4.99M1.09%+150,000+120.0%Added
Morgan Stanley264,907$4.81M0.00%+264,897+2,648,970.0%Added
Velan Capital Investment Management LP263,642$4.79M2.79%00.0%Unchanged
FMR LLC220,300$4.00M0.00%+220,300New
Ameriprise Financial Inc217,974$3.96M0.00%+4,402+2.1%Added
Jain Global LLC217,292$3.95M0.04%+217,292New
Susquehanna International Group, LLP210,994$3.83M0.01%+163,596+345.2%Added
Boothbay Fund Management, LLC202,127$3.67M0.10%−26,170−11.5%Reduced
BNP Paribas Arbitrage, SA197,747$3.59M0.00%+197,742+3,954,840.0%Added
SummitTX Capital, L.P.195,873$3.56M0.11%+195,873New
Nan Fung Trinity (HK) Ltd189,000$3.43M0.27%+189,000New
Jane Street Group, LLC178,855$3.25M0.00%+178,855New
Geode Capital Management, LLC166,152$3.02M0.00%+61,963+59.5%Added
Superstring Capital Management LP153,313$2.78M1.49%−34,767−18.5%Reduced
Deutsche Bank AG150,000$2.72M0.00%+150,000New
Two Sigma Investments, LP148,237$2.69M0.00%+98,995+201.0%Added
Perceptive Advisors LLC139,667$2.54M0.05%00.0%Unchanged
StemPoint Capital LP135,552$2.46M0.42%+135,552New
Moody Aldrich Partners LLC133,231$2.42M0.45%+133,231New
Squadron Capital Management LLC130,000$2.36M1.05%+130,000New
Great Point Partners LLC124,666$2.26M0.73%+124,666New
Barclays PLC105,814$1.92M0.00%+96,468+1,032.2%Added
HighVista Strategies LLC95,631$1.74M0.45%+67,853+244.3%Added
Standard Life Aberdeen plc95,426$1.73M0.00%+22,626+31.1%Added
Fred Alger Management, LLC80,092$1.45M0.01%+80,092New
State Street Corp79,254$1.44M0.00%+33,800+74.4%Added
Sio Capital Management, LLC72,173$1.31M0.22%00.0%Unchanged
Goldman Sachs Group Inc65,313$1.19M0.00%+65,313New
Qube Research & Technologies Ltd64,463$1.17M0.00%+64,463New
Seven Fleet Capital Management LP63,343$1.15M0.78%+63,343New
683 Capital Management, LLC56,850$1.03M0.09%+56,850New
Quadrature Capital Ltd53,044$963.3K0.01%−1,955−3.6%Reduced
Caption Management, LLC52,641$956.0K0.04%+52,641New
Woodline Partners LP52,041$945.1K0.00%+52,041New
Atom Investors LP51,194$929.7K0.07%+51,194New
Two Sigma Advisers, LP49,400$897.1K0.00%+49,400New
JPMorgan Chase & Co44,431$806.9K0.00%+42,858+2,724.6%Added
Walleye Capital LLC41,693$757.1K0.00%−3,050−6.8%Reduced
Artia Global Partners LP41,570$754.9K0.12%+41,570New
Squarepoint Ops LLC40,854$741.9K0.00%+40,854New
XTX Topco Ltd40,458$734.7K0.02%+26,508+190.0%Added
ExodusPoint Capital Management, LP32,267$586.0K0.01%+32,267New
Northern Trust Corp32,204$584.8K0.00%+13,629+73.4%Added
Ikarian Capital, LLC31,106$564.9K0.07%−128,671−80.5%Reduced
Glenmede Trust Co NA20,450$371.4K0.00%+20,450New
Omers Administration Corp19,600$355.9K0.00%+19,600New
Renaissance Technologies LLC18,300$332.3K0.00%−80,400−81.5%Reduced
Hudson Bay Capital Management LP16,771$304.6K0.00%+16,771New
Envestnet Asset Management Inc16,039$291.3K0.00%+16,039New
Persistent Asset Partners Ltd15,087$274.0K0.13%+15,087New
Jump Financial, LLC13,092$237.8K0.00%+13,092New
Tower Research Capital LLC (TRC)8,737$158.7K0.00%+8,711+33,503.8%Added
Belvedere Trading LLC4,526$82.2K0.02%+4,526New
US Bancorp2,733$49.6K0.00%+2,733New
PFS Partners, LLC2,000$36.3K0.02%+1,000+100.0%Added
Acadian Asset Management LLC1,471$26.0K0.00%+1,471New
Citigroup Inc1,143$20.8K0.00%+743+185.8%Added
Group One Trading, L.P.1$180.00%−280−99.6%Reduced
Advisor Group Holdings, Inc.1$180.00%−1−50.0%Reduced
Parallel Advisors, LLC1$180.00%00.0%Unchanged
Key Financial Inc1$180.00%00.0%Unchanged
Activest Wealth Management1$180.00%00.0%Unchanged
Ally Bridge Group (NY) LLC0$00.00%−178,100−100.0%Sold out
Deep Track Capital, LP0$00.00%−144,600−100.0%Sold out
Exome Asset Management LLC0$00.00%−100,036−100.0%Sold out
Adviser Investments LLC0$00.00%−86,516−100.0%Sold out
Cantor Fitzgerald, L. P.0$00.00%−85,247−100.0%Sold out
DLD Asset Management, LP0$00.00%−75,000−100.0%Sold out
Landscape Capital Management, L.L.C.0$00.00%−33,337−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−32,393−100.0%Sold out
Birchview Capital, LP0$00.00%−31,000−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−24,628−100.0%Sold out
Dimensional Fund Advisors LP0$00.00%−11,215−100.0%Sold out
BIT Capital GmbH0$00.00%−1,929−100.0%Sold out
Simplex Trading, LLC0$00.00%−748−100.0%Sold out
SBI Securities Co., Ltd.0$00.00%−23−100.0%Sold out
Avion Wealth0$00.00%−5−100.0%Sold out