Skip to main content
Livermore
Livermore
ZHEN

Ikarian Capital, LLC

SEC CIK
0001778253
Latest filing
Aug 14, 2026

Holdings in Q2 2024

Holdings as of Jun 30, 2024, filed Aug 14, 2024. Long positions only; changes compare share counts with Q1 2024.

Institution overview
Positions
85
+3 vs. Q1 2024
Portfolio value
$320.5M
−$47.2M (−12.8%) vs. Q1 2024
Filed
Aug 14, 2024
SEC
Holdings of Ikarian Capital, LLC in Q2 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
SRPTSarepta Therapeutics, Inc.COM203,612$32.2M10.0%+51,334+33.7%AddedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM588,818$26.4M8.2%−54,933−8.5%ReducedHistory
TARSTarsus Pharmaceuticals, Inc.COM800,277$21.8M6.8%+90,000+12.7%AddedHistory
SLNOSoleno Therapeutics IncCOM445,451$18.2M5.7%−119,960−21.2%ReducedHistory
CRBPCorbus Pharmaceuticals Holdings, Inc.COM NEW309,540$14.0M4.4%−249,731−44.7%ReducedHistory
ELVNEnliven Therapeutics, Inc.COM586,552$13.7M4.3%+586,552NewHistory
AMGNAmgen IncStock38,300$12.0M3.7%+38,300NewHistory
NUVLNuvalent, Inc.COM151,601$11.5M3.6%+50,000+49.2%AddedHistory
CYTKCytokinetics IncCOM NEW170,147$9.22M2.9%+25,000+17.2%AddedHistory
NRIXNurix Therapeutics, Inc.COM440,500$9.19M2.9%+140,500+46.8%AddedHistory
BBIOBridgeBio Pharma, Inc.COM332,013$8.41M2.6%+50,000+17.7%AddedHistory
CPRXCatalyst Pharmaceuticals, Inc.COM518,386$8.03M2.5%00.0%UnchangedHistory
VKTXViking Therapeutics, Inc.COM138,262$7.33M2.3%+138,262NewHistory
IMVTImmunovant, Inc.COM276,925$7.31M2.3%00.0%UnchangedHistory
RNACCartesian Therapeutics, Inc.COM NEW242,370$6.55M2.0%+242,370NewHistory
SLRNACELYRIN, Inc.COM1,475,074$6.51M2.0%−89,266−5.7%ReducedHistory
NBIXNeurocrine Biosciences IncStock40,000$5.51M1.7%+40,000NewHistory
PYXSPyxis Oncology, Inc.COMMON STOCK1,662,408$5.50M1.7%00.0%UnchangedHistory
ARQTArcutis Biotherapeutics, Inc.COM489,642$4.55M1.4%−100,000−17.0%ReducedHistory
RCKTRocket Pharmaceuticals, Inc.COM197,096$4.24M1.3%−100,000−33.7%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM107,187$4.18M1.3%00.0%UnchangedHistory
CRVOCervoMed Inc.COM237,345$4.06M1.3%00.0%UnchangedHistory
RZLTRezolute, Inc.COM NEW903,744$3.89M1.2%+903,744NewHistory
Cybin Ord23256X100COM13,953,488$3.78M1.2%00.0%Unchanged–
LENZLENZ Therapeutics, Inc.COM204,513$3.54M1.1%+119,513+140.6%AddedHistory
SLNSilence Therapeutics plcADS506,665$3.29M1.0%+506,665NewHistory
INBXInhibrx Biosciences, Inc.COM230,000$3.26M1.0%+230,000NewHistory
ABEOAbeona Therapeutics Inc.COM NEW768,593$3.26M1.0%−120,000−13.5%ReducedHistory
INSMINSMED IncCOM PAR $.0147,835$3.20M1.0%−3,500−6.8%ReducedHistory
TERNTerns Pharmaceuticals, Inc.COM458,497$3.12M1.0%+370,000+418.1%AddedHistory
VRNAVerona Pharma plcSPONSORED ADS201,116$2.91M0.9%−174,194−46.4%ReducedHistory
WVEWave Life Sciences, Inc.SHS575,088$2.87M0.9%−15,000−2.5%ReducedHistory
JSPRJasper Therapeutics, Inc.COM NEW105,175$2.39M0.7%00.0%UnchangedHistory
LRMRLarimar Therapeutics, Inc.COM323,528$2.35M0.7%−115,000−26.2%ReducedHistory
RCUSArcus Biosciences, Inc.COM145,000$2.21M0.7%+145,000NewHistory
QTTBQ32 Bio Inc.COM109,094$1.96M0.6%+86,759+388.4%AddedHistory
ELEVElevation Acquisition Group Inc.COM690,089$1.86M0.6%+542,000+366.0%AddedHistory
ANNXAnnexon, Inc.COM380,000$1.86M0.6%−1,025,000−73.0%ReducedHistory
CMPSCOMPASS Pathways plcSPONSORED ADS302,908$1.83M0.6%+302,908NewHistory
NKTRNektar TherapeuticsCOM1,312,405$1.63M0.5%+1,312,405NewHistory
SRRKScholar Rock Holding CorpCOM183,701$1.53M0.5%−108,000−37.0%ReducedHistory
SGMTSagimet Biosciences Inc.COM SER A412,565$1.41M0.4%00.0%UnchangedHistory
TRMLTourmaline Bio, Inc.COM108,483$1.40M0.4%00.0%UnchangedHistory
IBIOiBio, Inc.COM NEW600,000$1.27M0.4%00.0%UnchangedHistory
IFRXInflaRx N.V.COM704,987$1.23M0.4%00.0%UnchangedHistory
Achilles Therapeutics PLC00449L102SPONSORED ADS1,443,181$1.18M0.4%00.0%Unchanged–
DFTXDefinium Therapeutics, Inc.Stock162,481$1.17M0.4%−135,000−45.4%ReducedHistory
ITOSiTeos Therapeutics, Inc.COM78,574$1.17M0.4%−22,751−22.5%ReducedHistory
KODKodiak Sciences Inc.COM476,586$1.12M0.3%00.0%UnchangedHistory
ROIVRoivant Sciences Ltd.SHS100,609$1.06M0.3%00.0%UnchangedHistory
NUVBNuvation Bio Inc.COM CL A358,282$1.05M0.3%−275,000−43.4%ReducedHistory
TECXTectonic Therapeutic, Inc.COM62,836$1.03M0.3%00.0%UnchangedConverted for a 1-for-12 splitHistory
VTYXVentyx Biosciences, Inc.COM442,647$1.02M0.3%−65,000−12.8%ReducedHistory
ALLKAllakos Inc.COM972,675$972.7K0.3%+40,000+4.3%AddedHistory
MGNXMacrogenics IncCOM200,079$850.3K0.3%−118,088−37.1%ReducedHistory
DCTHDelcath Systems, Inc.COM NEW100,370$840.1K0.3%+100,370NewHistory
MRNSMarinus Pharmaceuticals, Inc.COM NEW706,154$826.2K0.3%+168,229+31.3%AddedHistory
PRQRProQR Therapeutics N.V.SHS EURO483,583$802.7K0.3%00.0%UnchangedHistory
VERUVeru Inc.COM946,382$796.2K0.2%00.0%UnchangedHistory
LYELLyell Immunopharma, Inc.COM526,066$762.8K0.2%+526,066NewHistory
CLYMClimb Bio, Inc.COM100,000$711.0K0.2%+100,000NewHistory
AVTXAvalo Therapeutics, Inc.COM NEW54,730$682.5K0.2%+8,082+17.3%AddedHistory
ABOSAcumen Pharmaceuticals, Inc.COM266,435$644.8K0.2%00.0%UnchangedHistory
MISTMilestone Pharmaceuticals Inc.COM466,019$619.8K0.2%00.0%UnchangedHistory
JBIOJade Biosciences, Inc.COM367,965$610.8K0.2%00.0%UnchangedHistory
IMTXImmatics N.V.SHS49,415$574.2K0.2%00.0%UnchangedHistory
IMUXImmunic, Inc.COM493,496$547.8K0.2%−1,118,882−69.4%ReducedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM274,551$521.6K0.2%−56,900−17.2%ReducedHistory
KZRKezar Life Sciences, Inc.COM868,992$521.4K0.2%00.0%UnchangedHistory
RAPTRAPT Therapeutics, Inc.COM154,625$471.6K0.1%00.0%UnchangedHistory
VYGRVoyager Therapeutics, Inc.COM55,857$441.8K0.1%−125,000−69.1%ReducedHistory
ANEBAnebulo Pharmaceuticals, Inc.COM157,862$431.0K0.1%00.0%UnchangedHistory
FTHFaeth Therapeutics, Inc.COM650,000$403.1K0.1%+650,000NewHistory
TARAProtara Therapeutics, Inc.COM STK180,712$375.9K0.1%−21,989−10.8%ReducedHistory
NYXHNyxoah SACOMMONSTOCK50,699$356.9K0.1%00.0%UnchangedHistory
KPTIKaryopharm Therapeutics Inc.COM409,355$355.2K0.1%00.0%UnchangedHistory
LYRALyra Therapeutics, Inc.COM1,056,829$292.4K0.1%00.0%UnchangedHistory
AEONAEON Biopharma, Inc.CL A257,977$270.9K0.1%00.0%UnchangedHistory
TPSTTempest Therapeutics, Inc.COM105,600$231.3K0.1%00.0%UnchangedHistory
CMMBChemomab Therapeutics Ltd.SPONSORED ADS213,392$196.3K0.1%00.0%UnchangedHistory
RLMDRelmada Therapeutics, Inc.COM40,369$121.1K<0.1%00.0%UnchangedHistory
STOKStoke Therapeutics, Inc.COM6,816$92.1K<0.1%00.0%UnchangedHistory
SYBXSynlogic, Inc.COM NEW20,448$30.7K<0.1%00.0%UnchangedHistory
BCLIBrainstorm Cell Therapeutics Inc.COM NEW90,242$30.5K<0.1%00.0%UnchangedHistory
CTMXCytomX Therapeutics, Inc.COM8,924$10.9K<0.1%+8,924NewHistory

Options (20)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Ikarian Capital, LLC in Q2 2024
SecurityClassPutsCalls
ALNYAlnylam Pharmaceuticals, Inc.COM$36.5M$36.5M
INSMINSMED IncCOM PAR $.01$4.75M$34.0M
PRAXPraxis Precision Medicines, Inc.COM NEW$17.5M$12.4M
AMGNAmgen IncStock–$18.7M
SRPTSarepta Therapeutics, Inc.COM–$15.8M
BBIOBridgeBio Pharma, Inc.COM–$15.2M
NBIXNeurocrine Biosciences IncStock–$13.8M
AREAlexandria Real Estate Equities, Inc.COM$8.57M–
AZNAstraZeneca PLCSPONSORED ADR–$8.52M
CORTCorcept Therapeutics IncCOM–$6.04M
GTHXG1 Therapeutics, Inc.COM$2.93M$2.79M
VRDNViridian Therapeutics, Inc.COM$3.63M$1.30M
SANASana Biotechnology, Inc.COM$2.18M$2.18M
ANVSAnnovis Bio, Inc.COM$3.18M$297.8K
IMVTImmunovant, Inc.COM–$2.64M
GPCRStructure Therapeutics Inc.SPONSORED ADS$1.14M$1.14M
PYXSPyxis Oncology, Inc.COMMON STOCK–$1.19M
RAPTRAPT Therapeutics, Inc.COM–$610.0K
JBIOJade Biosciences, Inc.COM–$166.0K
ABEOAbeona Therapeutics Inc.COM NEW–$72.5K

Sold out since Q1 2024 (13)

Positions held at the end of Q1 2024 that are gone from this filing.

Positions of Ikarian Capital, LLC sold out since Q1 2024
SecurityClassShares in Q1 2024Value in Q1 2024% of portfolio in Q1 2024History
ALPNAlpine Immune Sciences, Inc.COM261,365$10.4M2.8%History
PRAXPraxis Precision Medicines, Inc.COM NEW168,388$10.3M2.8%History
ALNYAlnylam Pharmaceuticals, Inc.COM51,541$7.70M2.1%History
QUREuniQure N.V.SHS469,133$2.44M0.7%History
APLSApellis Pharmaceuticals, Inc.COM35,092$2.06M0.6%History
ATXSAstria Therapeutics, Inc.COM140,687$1.98M0.5%History
IRONDisc Medicine, Inc.COM25,372$1.58M0.4%History
HOOKHOOKIPA Pharma Inc.COM530,776$377.9K0.1%History
EYPTEyePoint, Inc.COM NEW1,047$21.6K<0.1%History
FNCHFinch Therapeutics Group, Inc.COM NEW6,892$18.1K<0.1%History
TYRATyra Biosciences, Inc.COM501$8.22K<0.1%History
Aslan Pharmaceuticals Ltd04522R200SPON ADS NEW35,420$6.27K<0.1%–
LBPHLongboard Pharmaceuticals, Inc.COM236$5.10K<0.1%History