Sphera Funds Management Ltd.
- SEC CIK
- 0001496201
- Latest filing
- Aug 14, 2026
Holdings in Q2 2026
Holdings as of Jun 30, 2026, filed Aug 14, 2026. Long positions only; changes compare share counts with Q1 2026.
- Positions
- 97
- +5 vs. Q1 2026
- Portfolio value
- $698.8M
- +$117.3M (+20.2%) vs. Q1 2026
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| TEVATeva Pharmaceutical Industries Ltd | SPONSORED ADS | 1,500,082 | $50.8M | 7.3% | +363,107+31.9% | Added | History |
| MLYSMineralys Therapeutics, Inc. | COM | 1,469,971 | $39.7M | 5.7% | +130,000+9.7% | Added | History |
| TSEMTower Semiconductor Ltd | SHS NEW | 108,265 | $28.2M | 4.0% | −37,470−25.7% | Reduced | History |
| SNDXSyndax Pharmaceuticals Inc | COM | 1,014,606 | $22.2M | 3.2% | +290,043+40.0% | Added | History |
| BIIBBiogen Inc. | COM | 96,626 | $20.9M | 3.0% | +4,100+4.4% | Added | History |
| RAREUltragenyx Pharmaceutical Inc. | COM | 588,494 | $19.6M | 2.8% | −220,839−27.3% | Reduced | History |
| BMRNBiomarin Pharmaceutical Inc | COM | 328,550 | $18.8M | 2.7% | +188,650+134.8% | Added | History |
| CYTKCytokinetics Inc | COM NEW | 219,987 | $18.7M | 2.7% | +180,170+452.5% | Added | History |
| BBIOBridgeBio Pharma, Inc. | COM | 245,346 | $18.3M | 2.6% | +1000.0% | Added | History |
| COGTCogent Biosciences, Inc. | COM | 459,340 | $17.8M | 2.5% | +43,000+10.3% | Added | History |
| NVMINova Ltd. | COM | 25,169 | $13.7M | 2.0% | −28,197−52.8% | Reduced | History |
| INSMINSMED Inc | COM PAR $.01 | 118,800 | $12.7M | 1.8% | +118,800 | New | History |
| MAZEMaze Therapeutics, Inc. | COM | 417,564 | $12.5M | 1.8% | +190,221+83.7% | Added | History |
| AZNAstraZeneca PLC | ADR | 62,530 | $11.9M | 1.7% | 00.0% | Unchanged | History |
| SNYSanofi | SPONSORED ADR | 269,515 | $11.5M | 1.6% | 00.0% | Unchanged | History |
| HELPCybin Inc. | COM NEW | 1,620,753 | $10.7M | 1.5% | +633,663+64.2% | Added | History |
| LLYEli Lilly & Co | Stock | 8,040 | $9.64M | 1.4% | −1,000−11.1% | Reduced | History |
| MDGLMadrigal Pharmaceuticals, Inc. | COM | 17,419 | $9.35M | 1.3% | +8,379+92.7% | Added | History |
| TRVITrevi Therapeutics, Inc. | COM | 499,029 | $9.31M | 1.3% | −75,000−13.1% | Reduced | History |
| ACADAcadia Pharmaceuticals Inc | COM | 356,534 | $9.02M | 1.3% | +100,332+39.2% | Added | History |
| CLDXCelldex Therapeutics, Inc. | COM NEW | 240,868 | $8.96M | 1.3% | −2,707−1.1% | Reduced | History |
| RYTMRhythm Pharmaceuticals, Inc. | COM | 80,400 | $8.93M | 1.3% | +80,400 | New | History |
| ORICOric Pharmaceuticals, Inc. | COM | 752,983 | $8.15M | 1.2% | +215,355+40.1% | Added | History |
| LRCXLam Research Corp | Stock | 18,470 | $8.00M | 1.1% | +18,470 | New | History |
| AMATApplied Materials Inc | Stock | 11,040 | $7.98M | 1.1% | +11,040 | New | History |
| TNGXTango Therapeutics, Inc. | COM | 254,250 | $7.95M | 1.1% | −89,313−26.0% | Reduced | History |
| NVSNovartis AG | ADR | 50,000 | $7.83M | 1.1% | +13,000+35.1% | Added | History |
| Solaredge Technologies, Inc.83417MAE4 | NOTE 2.250% 7/0 | 4,000,000 | $7.75M | 1.1% | 00.0% | Unchanged | – |
| VORVor Biopharma Inc. | COM NEW | 416,417 | $7.67M | 1.1% | +94,500+29.4% | Added | History |
| ABBVAbbVie Inc. | Stock | 30,256 | $7.61M | 1.1% | 00.0% | Unchanged | History |
| MRKMerck & Co., Inc. | Stock | 58,600 | $7.53M | 1.1% | +10,000+20.6% | Added | History |
| JNJJohnson & Johnson | Stock | 28,831 | $7.32M | 1.0% | 00.0% | Unchanged | History |
| IDYAIDEAYA Biosciences, Inc. | COM | 196,408 | $7.32M | 1.0% | +196,408 | New | History |
| IMTXImmatics N.V. | SHS | 720,057 | $7.29M | 1.0% | +23,952+3.4% | Added | History |
| NVCTNuvectis Pharma, Inc. | COM | 382,945 | $7.04M | 1.0% | +382,945 | New | History |
| PFEPfizer Inc | Stock | 286,000 | $6.89M | 1.0% | +100,000+53.8% | Added | History |
| HRMYHarmony Biosciences Holdings, Inc. | COM | 176,663 | $6.43M | 0.9% | +176,663 | New | History |
| XENEXenon Pharmaceuticals Inc. | COM | 105,000 | $6.34M | 0.9% | −22,000−17.3% | Reduced | History |
| CLYMClimb Bio, Inc. | COM | 483,747 | $6.31M | 0.9% | +64,500+15.4% | Added | History |
| ZBIOZenas BioPharma, Inc. | COM | 230,834 | $5.86M | 0.8% | +16,500+7.7% | Added | History |
| NVONovo Nordisk A S | ADR | 120,677 | $5.79M | 0.8% | 00.0% | Unchanged | History |
| ELVNEnliven Therapeutics, Inc. | COM | 112,765 | $5.72M | 0.8% | −40,500−26.4% | Reduced | History |
| PRLDPrelude Therapeutics Inc | COM | 1,019,832 | $5.44M | 0.8% | +461,493+82.7% | Added | History |
| GSKGSK plc | ADR | 102,000 | $5.35M | 0.8% | −20,000−16.4% | Reduced | History |
| FBRXForte Biosciences, Inc. | COM NEW | 249,693 | $5.31M | 0.8% | +64,709+35.0% | Added | History |
| BIOABioAge Labs, Inc. | COM | 213,671 | $5.24M | 0.7% | +127,153+147.0% | Added | History |
| SRRKScholar Rock Holding Corp | COM | 94,265 | $5.18M | 0.7% | 00.0% | Unchanged | History |
| MSLESatellos Bioscience Inc. | COM | 652,590 | $5.07M | 0.7% | +163,383+33.4% | Added | History |
| PALIPalisade Bio, Inc. | COM | 2,257,106 | $4.72M | 0.7% | +523,635+30.2% | Added | History |
| ELDNEledon Pharmaceuticals, Inc. | COM | 1,191,187 | $4.69M | 0.7% | −580,944−32.8% | Reduced | History |
| VSTVistra Corp. | Stock | 29,450 | $4.67M | 0.7% | +29,450 | New | History |
| TLNTalen Energy Corp | COM | 12,135 | $4.66M | 0.7% | +12,135 | New | History |
| SVRASavara Inc | COM | 756,164 | $4.66M | 0.7% | +17,000+2.3% | Added | History |
| IRONDisc Medicine, Inc. | COM | 63,538 | $4.65M | 0.7% | +10,000+18.7% | Added | History |
| Global X FDS37954Y442 | CLOUD COMPUTNG | 195,900 | $4.45M | 0.6% | +195,900 | New | – |
| DYNDyne Therapeutics, Inc. | COM | 199,594 | $4.43M | 0.6% | +39,000+24.3% | Added | History |
| RLAYRelay Therapeutics, Inc. | COM | 233,836 | $4.38M | 0.6% | −174,600−42.7% | Reduced | History |
| AVTXAvalo Therapeutics, Inc. | COM NEW | 232,294 | $4.29M | 0.6% | +232,294 | New | History |
| PMNProMIS Neurosciences Inc. | COM SHS | 325,591 | $4.28M | 0.6% | 00.0% | Unchanged | History |
| BCRXBiocryst Pharmaceuticals Inc | COM | 422,051 | $4.22M | 0.6% | −444,413−51.3% | Reduced | History |
| RVMDRevolution Medicines, Inc. | COM | 22,400 | $4.20M | 0.6% | −32,710−59.4% | Reduced | History |
| CABACabaletta Bio, Inc. | COM | 1,329,012 | $4.13M | 0.6% | +1,329,012 | New | History |
| GENBGenerate Biomedicines, Inc. | COM SHS | 245,000 | $4.13M | 0.6% | +60,000+32.4% | Added | History |
| MDWDMediWound Ltd. | SHS NEW | 273,192 | $4.02M | 0.6% | 00.0% | Unchanged | History |
| ACOGAlpha Cognition Inc. | COM NEW | 545,816 | $3.94M | 0.6% | −21,800−3.8% | Reduced | History |
| WVEWave Life Sciences, Inc. | SHS | 638,272 | $3.71M | 0.5% | +90,000+16.4% | Added | History |
| CRVSCorvus Pharmaceuticals, Inc. | COM | 244,961 | $3.66M | 0.5% | −3,000−1.2% | Reduced | History |
| OVIDOvid Therapeutics Inc. | COM | 1,353,000 | $3.64M | 0.5% | −269,828−16.6% | Reduced | History |
| BBOTBridgeBio Oncology Therapeutics, Inc. | COM NEW | 460,985 | $3.51M | 0.5% | +460,985 | New | History |
| CTMXCytomX Therapeutics, Inc. | COM | 879,000 | $3.30M | 0.5% | +659,000+299.5% | Added | History |
| PRQRProQR Therapeutics N.V. | SHS EURO | 1,757,458 | $3.27M | 0.5% | +1,757,458 | New | History |
| ALNYAlnylam Pharmaceuticals, Inc. | COM | 10,800 | $3.25M | 0.5% | +10,800 | New | History |
| KURAKura Oncology, Inc. | COM | 295,039 | $3.24M | 0.5% | −483−0.2% | Reduced | History |
| KODKodiak Sciences Inc. | COM | 81,796 | $3.19M | 0.5% | −33,000−28.7% | Reduced | History |
| ORAOrmat Technologies, Inc. | COM | 28,015 | $3.05M | 0.4% | −40,235−59.0% | Reduced | History |
| CTNMContineum Therapeutics, Inc. | CL A | 183,475 | $3.01M | 0.4% | +10,000+5.8% | Added | History |
| LRMRLarimar Therapeutics, Inc. | COM | 926,004 | $2.82M | 0.4% | +926,004 | New | History |
| IMMXImmix Biopharma, Inc. | COM | 270,000 | $2.78M | 0.4% | +270,000 | New | History |
| AMGNAmgen Inc | Stock | 7,500 | $2.72M | 0.4% | 00.0% | Unchanged | History |
| BHVNBiohaven Ltd. | COM | 164,437 | $2.45M | 0.4% | −429,563−72.3% | Reduced | History |
| CEGConstellation Energy Corp | Stock | 9,850 | $2.45M | 0.4% | +9,850 | New | History |
| VSTMVerastem, Inc. | COM NEW | 632,632 | $2.42M | 0.3% | +288,954+84.1% | Added | History |
| TENXTenax Therapeutics, Inc. | COM NEW | 120,200 | $1.75M | 0.3% | −15,815−11.6% | Reduced | History |
| TSHATaysha Gene Therapies, Inc. | COM SHS | 250,000 | $1.70M | 0.2% | +250,000 | New | History |
| GPCRStructure Therapeutics Inc. | SPONSORED ADS | 28,600 | $1.53M | 0.2% | −22,200−43.7% | Reduced | History |
| UPBUpstream Bio, Inc. | COM | 219,700 | $1.52M | 0.2% | −138,300−38.6% | Reduced | History |
| VYGRVoyager Therapeutics, Inc. | COM | 427,554 | $1.50M | 0.2% | −42,207−9.0% | Reduced | History |
| ORGOOrganogenesis Holdings Inc. | COM | 550,000 | $1.34M | 0.2% | 00.0% | Unchanged | History |
| IKTInhibikase Therapeutics, Inc. | COM NEW | 649,309 | $1.32M | 0.2% | +649,309 | New | History |
| CRISCuris Inc | COM | 98,996 | $1.03M | 0.1% | −1,895,941−95.0% | Reduced | History |
| STTKShattuck Labs, Inc. | COM | 86,461 | $600.0K | 0.1% | −194,325−69.2% | Reduced | History |
| TRAXFirst Tracks Biotherapeutics, Inc. | ORD SHS | 27,876 | $560.9K | 0.1% | +27,876 | New | History |
| SKYESkye Bioscience, Inc. | COM NEW | 678,928 | $470.7K | 0.1% | 00.0% | Unchanged | History |
| TRAWTraws Pharma, Inc. | COM NEW | 398,486 | $336.0K | <0.1% | +398,486 | New | History |
| EVMNEvommune, Inc. | COM SHS | 22,632 | $300.8K | <0.1% | −55,602−71.1% | Reduced | History |
| HOWLWerewolf Therapeutics, Inc. | COM | 626,810 | $225.6K | <0.1% | 00.0% | Unchanged | History |
| APREAprea Therapeutics, Inc. | COM NEW | 270,000 | $216.6K | <0.1% | 00.0% | Unchanged | History |
Options (8)
Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.
| Security | Class | Puts | Calls |
|---|---|---|---|
| State Street SPDR S&P Biotech ETF78464A870 | ETF | $23.7M | – |
| BIIBBiogen Inc. | COM | – | $21.6M |
| CYTKCytokinetics Inc | COM NEW | – | $8.52M |
| PRAXPraxis Precision Medicines, Inc. | COM NEW | – | $4.18M |
| iShares Tr464287432 | 20 YR TR BD ETF | – | $4.06M |
| ABVXAbivax S.A. | SPONSORED ADS | $2.67M | – |
| TENXTenax Therapeutics, Inc. | COM NEW | – | $1.86M |
| ORICOric Pharmaceuticals, Inc. | COM | – | $1.08M |
Sold out since Q1 2026 (17)
Positions held at the end of Q1 2026 that are gone from this filing.
| Security | Class | Shares in Q1 2026 | Value in Q1 2026 | % of portfolio in Q1 2026 | History |
|---|---|---|---|---|---|
| FOLDAmicus Therapeutics, Inc. | COM | 603,377 | $8.72M | 1.5% | History |
| CLBTCellebrite DI Ltd. | ORDINARY SHARES | 631,521 | $8.70M | 1.5% | History |
| APLSApellis Pharmaceuticals, Inc. | COM | 214,914 | $8.65M | 1.5% | History |
| PANWPalo Alto Networks Inc | Stock | 52,800 | $8.46M | 1.5% | History |
| CAMTCamtek Ltd | ORD | 53,020 | $8.04M | 1.4% | History |
| SLNOSoleno Therapeutics Inc | COM | 216,281 | $7.24M | 1.2% | History |
| AMZNAmazon Com Inc | Stock | 31,940 | $6.65M | 1.1% | History |
| AAOIApplied Optoelectronics, Inc. | COM | 73,400 | $6.21M | 1.1% | History |
| ENPHEnphase Energy, Inc. | Stock | 142,419 | $5.38M | 0.9% | History |
| ZIMZIM Integrated Shipping Services Ltd. | SHS | 105,950 | $2.79M | 0.5% | History |
| SEDGSolaredge Technologies, Inc. | COM | 52,836 | $2.70M | 0.5% | History |
| IBITiShares Bitcoin Trust ETF | ETF | 59,505 | $2.29M | 0.4% | History |
| ASNDAscendis Pharma A/S | SPONSORED ADR | 8,000 | $1.83M | 0.3% | History |
| BMYBristol Myers Squibb Co | Stock | 17,500 | $1.06M | 0.2% | History |
| NICENICE Ltd. | SPONSORED ADR | 5,611 | $618.7K | 0.1% | History |
| DTILPrecision Biosciences Inc | COM NEW | 40,000 | $220.0K | <0.1% | History |
| FHTXFoghorn Therapeutics Inc. | COM | 12,224 | $58.4K | <0.1% | History |